Trait: Waldenstrom macroglobulinemia

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009441
Trait categories
Cancer
Immune system disorder
Metabolic disorder
Synonyms 9 synonyms
  • Waldenstroem's macroglobulinemia
  • Waldenstrom macroglobulinemia
  • Waldenstrom's macroglobulinaemia
  • Waldenstrom's macroglobulinemia
  • Waldenstrom's syndrome
  • Waldenström Macroglobulinemia
  • Waldenström macroglobulinemia
  • lymphoplasmacytic lymphoma with IgM gammopathy
  • macroglobulinemia of Waldenstrom
Mapped terms 15 mapped terms
  • DOID:0060901
  • GARD:0007872
  • GARD:7872
  • ICD10:C88.0
  • ICD10CM:C88.0
  • MEDGEN:6174
  • MESH:D008258
  • MONDO:0100280
  • MedDRA:10047801
  • NCIT:C80307
  • NORD:1834
  • OMIMPS:153600
  • ONCOTREE:WM
  • Orphanet:33226
  • UMLS:C0024419

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003452
(PRS2_WM)
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Waldenström macroglobulinemia Waldenstrom macroglobulinemia 2
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003452/ScoringFiles/PGS003452.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM017228 PGS003452
(PRS2_WM)
 PSS010176|
European Ancestry|
20,134 individuals
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Reported Trait: Chronic lymphocytic leukemia OR: 1.07 [1.01, 1.14] — — — —
PPM017236 PGS003452
(PRS2_WM)
 PSS010176|
European Ancestry|
20,134 individuals
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Reported Trait: Diffuse large B-cell lymphoma OR: 1.24 [1.18, 1.31] — — — —
PPM017244 PGS003452
(PRS2_WM)
 PSS010176|
European Ancestry|
20,134 individuals
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Reported Trait: Follicular lymphoma OR: 1.12 [1.05, 1.19] — — — —
PPM017252 PGS003452
(PRS2_WM)
 PSS010176|
European Ancestry|
20,134 individuals
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Reported Trait: Marginal zone lymphoma OR: 1.18 [1.07, 1.3] — — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS010176 — —
[
  • 10,629 cases
  • , 9,505 controls
]
 — European — NR Inter- Lymph Consortium