Trait: social interaction measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009592
Description Quantification, typically by a questionnaire, of some aspect of social interaction, such as engagement in social activities, or degree of contact with friends and family.
Trait category
Other measurement
Mapped term PMID:29970889

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001018
(GBE_BIN_FC10006160)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Attending social / leisure activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) social interaction measurement 2,912
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001018/ScoringFiles/PGS001018.txt.gz
PGS001019
(GBE_BIN_FC20006160)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Attending social / leisure activities (regular attendance at a gym or sports club) social interaction measurement 11,361
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001019/ScoringFiles/PGS001019.txt.gz
PGS001020
(GBE_BIN_FC50006160)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Attending social / leisure activities (regular attendance at an adult education class) social interaction measurement 220
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001020/ScoringFiles/PGS001020.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007853 PGS001018
(GBE_BIN_FC10006160)
 PSS003741|
African Ancestry|
6,383 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) — AUROC: 0.57396 [0.5576, 0.59032] R²: 0.01675
Incremental AUROC (full-covars): -0.00782
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.49703 [0.48018, 0.51389]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007854 PGS001018
(GBE_BIN_FC10006160)
 PSS003742|
East Asian Ancestry|
1,633 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) — AUROC: 0.57527 [0.54681, 0.60374] R²: 0.02162
Incremental AUROC (full-covars): -0.01137
PGS R2 (no covariates): 0.00034
PGS AUROC (no covariates): 0.48407 [0.4551, 0.51303]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007855 PGS001018
(GBE_BIN_FC10006160)
 PSS003743|
European Ancestry|
24,772 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) — AUROC: 0.58275 [0.57492, 0.59058] R²: 0.02479
Incremental AUROC (full-covars): 0.00287
PGS R2 (no covariates): 0.00278
PGS AUROC (no covariates): 0.52778 [0.51977, 0.53579]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007856 PGS001018
(GBE_BIN_FC10006160)
 PSS003744|
South Asian Ancestry|
7,477 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) — AUROC: 0.55963 [0.54607, 0.5732] R²: 0.01282
Incremental AUROC (full-covars): -0.00061
PGS R2 (no covariates): 0.00074
PGS AUROC (no covariates): 0.51312 [0.49938, 0.52686]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007857 PGS001018
(GBE_BIN_FC10006160)
 PSS003745|
European Ancestry|
67,254 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) — AUROC: 0.54214 [0.53736, 0.54692] R²: 0.00644
Incremental AUROC (full-covars): 0.00852
PGS R2 (no covariates): 0.00253
PGS AUROC (no covariates): 0.52663 [0.52182, 0.53145]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007858 PGS001019
(GBE_BIN_FC20006160)
 PSS003835|
African Ancestry|
3,021 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend sports club or gym in once a week or more often) — AUROC: 0.54407 [0.52357, 0.56457] R²: 0.00813
Incremental AUROC (full-covars): -0.00783
PGS R2 (no covariates): 0.00123
PGS AUROC (no covariates): 0.51554 [0.49496, 0.53612]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007859 PGS001019
(GBE_BIN_FC20006160)
 PSS003836|
East Asian Ancestry|
1,085 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend sports club or gym in once a week or more often) — AUROC: 0.58246 [0.5482, 0.61672] R²: 0.0292
Incremental AUROC (full-covars): 0.02535
PGS R2 (no covariates): 0.01412
PGS AUROC (no covariates): 0.55974 [0.52518, 0.5943]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007860 PGS001019
(GBE_BIN_FC20006160)
 PSS003837|
European Ancestry|
15,258 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend sports club or gym in once a week or more often) — AUROC: 0.57507 [0.56602, 0.58412] R²: 0.02282
Incremental AUROC (full-covars): 0.00636
PGS R2 (no covariates): 0.00715
PGS AUROC (no covariates): 0.54225 [0.53311, 0.55138]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007861 PGS001019
(GBE_BIN_FC20006160)
 PSS003838|
South Asian Ancestry|
4,460 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend sports club or gym in once a week or more often) — AUROC: 0.5442 [0.527, 0.5614] R²: 0.00767
Incremental AUROC (full-covars): -0.01443
PGS R2 (no covariates): 0.00058
PGS AUROC (no covariates): 0.50999 [0.49273, 0.52726]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007862 PGS001019
(GBE_BIN_FC20006160)
 PSS003839|
European Ancestry|
41,646 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend sports club or gym in once a week or more often) — AUROC: 0.55465 [0.54914, 0.56015] R²: 0.01246
Incremental AUROC (full-covars): 0.02052
PGS R2 (no covariates): 0.0089
PGS AUROC (no covariates): 0.54635 [0.54083, 0.55186]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007863 PGS001020
(GBE_BIN_FC50006160)
 PSS003964|
African Ancestry|
2,080 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend adult edication class in once a week or more often) — AUROC: 0.62457 [0.59746, 0.65168] R²: 0.05611
Incremental AUROC (full-covars): -0.00161
PGS R2 (no covariates): 4e-05
PGS AUROC (no covariates): 0.50528 [0.47691, 0.53364]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007864 PGS001020
(GBE_BIN_FC50006160)
 PSS003965|
East Asian Ancestry|
779 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend adult edication class in once a week or more often) — AUROC: 0.65214 [0.60399, 0.70029] R²: 0.08858
Incremental AUROC (full-covars): -0.016
PGS R2 (no covariates): 0.00657
PGS AUROC (no covariates): 0.44592 [0.39358, 0.49825]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007865 PGS001020
(GBE_BIN_FC50006160)
 PSS003966|
European Ancestry|
9,800 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend adult edication class in once a week or more often) — AUROC: 0.63249 [0.61991, 0.64506] R²: 0.05833
Incremental AUROC (full-covars): 0.00299
PGS R2 (no covariates): 0.00271
PGS AUROC (no covariates): 0.52692 [0.51362, 0.54021]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007866 PGS001020
(GBE_BIN_FC50006160)
 PSS003967|
South Asian Ancestry|
3,118 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend adult edication class in once a week or more often) — AUROC: 0.60534 [0.57645, 0.63422] R²: 0.03531
Incremental AUROC (full-covars): 0.00261
PGS R2 (no covariates): 0.00153
PGS AUROC (no covariates): 0.52735 [0.49684, 0.55785]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007867 PGS001020
(GBE_BIN_FC50006160)
 PSS003968|
European Ancestry|
26,122 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Leisure/social activities (attend adult edication class in once a week or more often) — AUROC: 0.63479 [0.62646, 0.64311] R²: 0.05542
Incremental AUROC (full-covars): 0.00193
PGS R2 (no covariates): 0.00149
PGS AUROC (no covariates): 0.5218 [0.51302, 0.53058]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS003836 — —
[
  • 456 cases
  • , 629 controls
]
 — East Asian — UKB —
PSS003741 — —
[
  • 4,891 cases
  • , 1,492 controls
]
 — African unspecified — UKB —
PSS003742 — —
[
  • 1,018 cases
  • , 615 controls
]
 — East Asian — UKB —
PSS003743 — —
[
  • 17,791 cases
  • , 6,981 controls
]
 — European non-white British ancestry UKB —
PSS003744 — —
[
  • 4,862 cases
  • , 2,615 controls
]
 — South Asian — UKB —
PSS003745 — —
[
  • 47,929 cases
  • , 19,325 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS003837 — —
[
  • 8,025 cases
  • , 7,233 controls
]
 — European non-white British ancestry UKB —
PSS003838 — —
[
  • 1,790 cases
  • , 2,670 controls
]
 — South Asian — UKB —
PSS003839 — —
[
  • 21,289 cases
  • , 20,357 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS003964 — —
[
  • 535 cases
  • , 1,545 controls
]
 — African unspecified — UKB —
PSS003965 — —
[
  • 135 cases
  • , 644 controls
]
 — East Asian — UKB —
PSS003966 — —
[
  • 2,403 cases
  • , 7,397 controls
]
 — European non-white British ancestry UKB —
PSS003967 — —
[
  • 405 cases
  • , 2,713 controls
]
 — South Asian — UKB —
PSS003968 — —
[
  • 5,233 cases
  • , 20,889 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS003835 — —
[
  • 1,494 cases
  • , 1,527 controls
]
 — African unspecified — UKB —