Trait: feeling nervous measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009597
Description Quantification of whether an individual feels or felt nervous or "suffered from nerves".
Trait category
Other measurement
Mapped term PMID:29500382

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001017
(GBE_BIN2010)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Suffer from 'nerves' feeling nervous measurement 3,348
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001017/ScoringFiles/PGS001017.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007848 PGS001017
(GBE_BIN2010)
 PSS003652|
African Ancestry|
5,987 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Suffer from 'nerves' — AUROC: 0.51358 [0.49307, 0.53409] R²: 0.00091
Incremental AUROC (full-covars): -0.01868
PGS R2 (no covariates): 0.0002
PGS AUROC (no covariates): 0.49271 [0.47201, 0.51341]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007849 PGS001017
(GBE_BIN2010)
 PSS003653|
East Asian Ancestry|
1,473 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Suffer from 'nerves' — AUROC: 0.56758 [0.53117, 0.604] R²: 0.01953
Incremental AUROC (full-covars): -0.01086
PGS R2 (no covariates): 0.00022
PGS AUROC (no covariates): 0.51056 [0.47283, 0.54828]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007850 PGS001017
(GBE_BIN2010)
 PSS003654|
European Ancestry|
23,768 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Suffer from 'nerves' — AUROC: 0.56488 [0.556, 0.57377] R²: 0.01344
Incremental AUROC (full-covars): 0.00629
PGS R2 (no covariates): 0.00341
PGS AUROC (no covariates): 0.53323 [0.52425, 0.54221]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007851 PGS001017
(GBE_BIN2010)
 PSS003655|
South Asian Ancestry|
6,958 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Suffer from 'nerves' — AUROC: 0.58706 [0.57106, 0.60305] R²: 0.02294
Incremental AUROC (full-covars): -0.00056
PGS R2 (no covariates): 0.00138
PGS AUROC (no covariates): 0.52168 [0.50524, 0.53812]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007852 PGS001017
(GBE_BIN2010)
 PSS003656|
European Ancestry|
65,185 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Suffer from 'nerves' — AUROC: 0.55991 [0.55463, 0.56519] R²: 0.01151
Incremental AUROC (full-covars): 0.01586
PGS R2 (no covariates): 0.00563
PGS AUROC (no covariates): 0.5416 [0.53628, 0.54693]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS003652 — —
[
  • 915 cases
  • , 5,072 controls
]
 — African unspecified — UKB —
PSS003653 — —
[
  • 294 cases
  • , 1,179 controls
]
 — East Asian — UKB —
PSS003654 — —
[
  • 4,960 cases
  • , 18,808 controls
]
 — European non-white British ancestry UKB —
PSS003655 — —
[
  • 1,471 cases
  • , 5,487 controls
]
 — South Asian — UKB —
PSS003656 — —
[
  • 14,228 cases
  • , 50,957 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)