| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0009749 |
| Description | A measurement of the age at which a person has the first sexual intercourse. | Trait category |
Other measurement
|
| Mapped term | PMID:27089180 |
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS001007 (GBE_INI2139) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Age at first sexual intercourse | age at first sexual intercourse measurement | 9,997 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001007/ScoringFiles/PGS001007.txt.gz |
| PGS001938 (portability-PLR_log_age_first_sex) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Age first had sexual intercourse | age at first sexual intercourse measurement | 64,164 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001938/ScoringFiles/PGS001938.txt.gz |
| PGS002156 (portability-ldpred2_log_age_first_sex) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Age first had sexual intercourse | age at first sexual intercourse measurement | 972,919 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002156/ScoringFiles/PGS002156.txt.gz |
| PGS002215 (portability-ldpred2_no_sex) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Age first had sexual intercourse | age at first sexual intercourse measurement | 633,660 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002215/ScoringFiles/PGS002215.txt.gz |
| PGS003520 (cont-decay-log_age_first_sex) |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Age first had sexual intercourse | age at first sexual intercourse measurement | 979,739 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003520/ScoringFiles/PGS003520.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM007798 | PGS001007 (GBE_INI2139) |
PSS004951| African Ancestry| 4,771 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | R²: 0.01638 [0.01026, 0.0225] Incremental R2 (full-covars): -0.00625 PGS R2 (no covariates): 0.0 [-0.00008, 0.00008] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007799 | PGS001007 (GBE_INI2139) |
PSS004952| East Asian Ancestry| 1,050 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | R²: 0.02181 [0.00812, 0.0355] Incremental R2 (full-covars): -0.00042 PGS R2 (no covariates): 0.00235 [-0.00223, 0.00693] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007800 | PGS001007 (GBE_INI2139) |
PSS004953| European Ancestry| 21,597 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | R²: 0.05384 [0.04839, 0.0593] Incremental R2 (full-covars): 0.02018 PGS R2 (no covariates): 0.02045 [0.01697, 0.02393] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007801 | PGS001007 (GBE_INI2139) |
PSS004954| South Asian Ancestry| 4,838 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | R²: 0.05962 [0.04945, 0.06979] Incremental R2 (full-covars): 0.00524 PGS R2 (no covariates): 0.00685 [0.00321, 0.01049] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007802 | PGS001007 (GBE_INI2139) |
PSS004955| European Ancestry| 59,599 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | R²: 0.06968 [0.06597, 0.07339] Incremental R2 (full-covars): 0.02181 PGS R2 (no covariates): 0.0245 [0.02219, 0.0268] |
age, sex, UKB array type, Genotype PCs | — |
| PPM010379 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS009437| European Ancestry| 17,510 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.2244 [0.2103, 0.2384] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010381 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS008765| European Ancestry| 5,704 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.162 [0.1366, 0.1872] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010382 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS008539| Greater Middle Eastern Ancestry| 781 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0725 [0.0014, 0.1428] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010383 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS008317| South Asian Ancestry| 3,788 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.1471 [0.1157, 0.1782] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010384 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS008094| East Asian Ancestry| 1,127 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0776 [0.0188, 0.1359] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010385 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS007881| African Ancestry| 1,805 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0537 [0.0073, 0.0999] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010386 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS008985| African Ancestry| 2,741 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0705 [0.033, 0.1078] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010380 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS009211| European Ancestry| 3,425 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.1979 [0.1654, 0.2299] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012097 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS008765| European Ancestry| 5,704 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.1716 [0.1463, 0.1967] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012098 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS008539| Greater Middle Eastern Ancestry| 781 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0837 [0.0127, 0.1539] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012095 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS009437| European Ancestry| 17,510 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.2443 [0.2304, 0.2582] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012096 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS009211| European Ancestry| 3,425 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.2086 [0.1763, 0.2405] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012099 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS008317| South Asian Ancestry| 3,788 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.1587 [0.1274, 0.1897] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012100 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS008094| East Asian Ancestry| 1,127 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0976 [0.0389, 0.1556] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012101 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS007881| African Ancestry| 1,805 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0626 [0.0163, 0.1087] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012102 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS008985| African Ancestry| 2,741 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0793 [0.0419, 0.1166] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012567 | PGS002215 (portability-ldpred2_no_sex) |
PSS009481| European Ancestry| 17,730 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0313 [0.0166, 0.046] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012570 | PGS002215 (portability-ldpred2_no_sex) |
PSS008583| Greater Middle Eastern Ancestry| 792 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): -0.0493 [-0.1194, 0.0213] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012571 | PGS002215 (portability-ldpred2_no_sex) |
PSS008361| South Asian Ancestry| 3,837 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): -0.0125 [-0.0442, 0.0192] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012572 | PGS002215 (portability-ldpred2_no_sex) |
PSS008138| East Asian Ancestry| 1,146 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.015 [-0.0434, 0.0734] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012573 | PGS002215 (portability-ldpred2_no_sex) |
PSS007925| African Ancestry| 1,855 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.012 [-0.0338, 0.0578] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012574 | PGS002215 (portability-ldpred2_no_sex) |
PSS009029| African Ancestry| 2,796 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): -0.0112 [-0.0484, 0.026] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012568 | PGS002215 (portability-ldpred2_no_sex) |
PSS009255| European Ancestry| 3,466 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.027 [-0.0064, 0.0603] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012569 | PGS002215 (portability-ldpred2_no_sex) |
PSS008809| European Ancestry| 5,786 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0161 [-0.0098, 0.0419] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM017448 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010883| European Ancestry| 17,510 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.05 | sex, age, deprivation index, PC1-16 | — |
| PPM017532 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010799| European Ancestry| 3,426 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.04 | sex, age, deprivation index, PC1-16 | — |
| PPM017700 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010547| Greater Middle Eastern Ancestry| 781 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM017784 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010211| European Ancestry| 2,080 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
| PPM017868 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010463| South Asian Ancestry| 3,788 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.02 | sex, age, deprivation index, PC1-16 | — |
| PPM017952 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010379| East Asian Ancestry| 1,128 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM018036 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010295| African Ancestry| 1,805 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM018120 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010715| African Ancestry| 2,741 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM017616 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010631| European Ancestry| 5,575 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS009029 | — | — | 2,796 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS007881 | — | — | 1,805 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS008138 | — | — | 1,146 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS010799 | — | — | 3,426 individuals, 38.0 % Male samples |
Mean = 54.2 years Sd = 7.5 years |
European | Polish | UKB | — |
| PSS010547 | — | — | 781 individuals, 60.0 % Male samples |
Mean = 52.6 years Sd = 7.9 years |
Greater Middle Eastern (Middle Eastern, North African or Persian) | Iranian | UKB | — |
| PSS008539 | — | — | 781 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS009437 | — | — | 17,510 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS010295 | — | — | 1,805 individuals, 36.0 % Male samples |
Mean = 51.7 years Sd = 7.7 years |
African American or Afro-Caribbean | Caribbean | UKB | — |
| PSS004951 | — | — | 4,771 individuals | — | African unspecified | — | UKB | — |
| PSS004952 | — | — | 1,050 individuals | — | East Asian | — | UKB | — |
| PSS004953 | — | — | 21,597 individuals | — | European | non-white British ancestry | UKB | — |
| PSS004954 | — | — | 4,838 individuals | — | South Asian | — | UKB | — |
| PSS004955 | — | — | 59,599 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS008809 | — | — | 5,786 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS007925 | — | — | 1,855 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS009211 | — | — | 3,425 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS008317 | — | — | 3,788 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS010715 | — | — | 2,741 individuals, 48.0 % Male samples |
Mean = 51.1 years Sd = 7.7 years |
African unspecified | Nigerian | UKB | — |
| PSS010463 | — | — | 3,788 individuals, 58.0 % Male samples |
Mean = 52.4 years Sd = 8.3 years |
South Asian | Indian | UKB | — |
| PSS008583 | — | — | 792 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS009481 | — | — | 17,730 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS010211 | — | — | 2,080 individuals, 45.0 % Male samples |
Mean = 58.0 years Sd = 7.1 years |
European | Ashkenazi | UKB | — |
| PSS008985 | — | — | 2,741 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS008094 | — | — | 1,127 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS009255 | — | — | 3,466 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS008361 | — | — | 3,837 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS010883 | — | — | 17,510 individuals, 46.0 % Male samples |
Mean = 56.5 years Sd = 7.9 years |
European | white British | UKB | — |
| PSS010631 | — | — | 5,575 individuals, 45.0 % Male samples |
Mean = 54.2 years Sd = 8.3 years |
European | Italian | UKB | — |
| PSS010379 | — | — | 1,128 individuals, 36.0 % Male samples |
Mean = 51.7 years Sd = 7.7 years |
East Asian | Chinese | UKB | — |
| PSS008765 | — | — | 5,704 individuals | — | European | Italy (South Europe) | UKB | — |