Trait: appendectomy

Experimental Factor Ontology (EFO) Information
Identifier EFO_0600086
Description Procedure to remove the appendix.
Trait category
Other trait
Mapped terms 3 mapped terms
  • NCIT:C51687
  • SNOMEDCT:80146002
  • doi:10.1101/2021.11.19.21266436

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
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Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001786
(1kgeur_gbmi_leaveUKBBout_Appendectomy_pst_eff_a1_b0.5_phiauto)
 PGP000262 |
Wang Y et al. Cell Genom (2023)
 Appendectomy appendectomy 899,660
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001786/ScoringFiles/PGS001786.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM009290 PGS001786
(1kgeur_gbmi_leaveUKBBout_Appendectomy_pst_eff_a1_b0.5_phiauto)
 PSS007709|
European Ancestry|
357,112 individuals
 PGP000262 |
Wang Y et al. Cell Genom (2023)
 Reported Trait: Appendectomy — AUROC: 0.574 Nagelkerke's R2 (covariates regressed out): 0.00175 sex,age,age2,age*sex,age^2*sex, 20PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007709 — —
[
  • 2,173 cases
  • , 354,938 controls
]
 — European — UKB —