Trait: Tinnitus

Trait Information
Identifier HP_0000360
Description Tinnitus is an auditory perception that can be described as the experience of sound, in the ear or i... n the head, in the absence of external acoustic stimulation.Show more
Trait category
Other trait
Synonyms 2 synonyms
  • Ringing in ears
  • Ringing in the ears
Mapped terms 4 mapped terms
  • SNOMEDCT_US:162349004
  • SNOMEDCT_US:162352007
  • SNOMEDCT_US:60862001
  • UMLS:C0040264

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
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Polygenic Score ID & Name
PGS Publication ID (PGP)
Reported Trait
Mapped Trait(s) (Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS001533
(GBE_QT_FC1004803)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Tinnitus severityTinnitus343
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001533/ScoringFiles/PGS001533.txt.gz
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
Evaluated Score
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM007260PGS001533
(GBE_QT_FC1004803)
PSS007611|
African Ancestry|
3,651 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Tinnitus severity——R²: 0.00963 [0.00491, 0.01435]
Incremental R2 (full-covars): 0.00027
PGS R2 (no covariates): 0.00038 [-0.00057, 0.00132]		age, sex, UKB array type, Genotype PCs—
PPM007261PGS001533
(GBE_QT_FC1004803)
PSS007612|
East Asian Ancestry|
770 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Tinnitus severity——R²: 0.04047 [0.02218, 0.05877]
Incremental R2 (full-covars): 0.0031
PGS R2 (no covariates): 0.00478 [-0.00174, 0.01131]		age, sex, UKB array type, Genotype PCs—
PPM007262PGS001533
(GBE_QT_FC1004803)
PSS007613|
European Ancestry|
11,174 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Tinnitus severity——R²: 0.01906 [0.0157, 0.02243]
Incremental R2 (full-covars): 0.00143
PGS R2 (no covariates): 0.00167 [0.00066, 0.00268]		age, sex, UKB array type, Genotype PCs—
PPM007263PGS001533
(GBE_QT_FC1004803)
PSS007614|
South Asian Ancestry|
4,731 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Tinnitus severity——R²: 0.02195 [0.01553, 0.02837]
Incremental R2 (full-covars): 0.00113
PGS R2 (no covariates): 0.00165 [-0.00014, 0.00345]		age, sex, UKB array type, Genotype PCs—
PPM007264PGS001533
(GBE_QT_FC1004803)
PSS007615|
European Ancestry|
27,484 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Tinnitus severity——R²: 0.01575 [0.01388, 0.01761]
Incremental R2 (full-covars): 0.0008
PGS R2 (no covariates): 0.00073 [0.00032, 0.00114]		age, sex, UKB array type, Genotype PCs—
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS007611——3,651 individuals—African unspecified—UKB—
PSS007612——770 individuals—East Asian—UKB—
PSS007613——11,174 individuals—Europeannon-white British ancestryUKB—
PSS007614——4,731 individuals—South Asian—UKB—
PSS007615——27,484 individuals—Europeanwhite British ancestryUKBTesting cohort (heldout set)
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