Trait: Self-injurious behavior

Trait Information
Identifier HP_0100716
Description
  • Self-aggression.
  • All of these actions can be impulsive, compulsive, or planned.
Trait category
Neurological disorder
Synonyms 6 synonyms
  • Autoagression
  • Self injury
  • Self-harm
  • Self-injurious behavior
  • Self-injurious behaviors
  • Self-injurious behaviours
Mapped terms 2 mapped terms
  • SNOMEDCT_US:248062006
  • UMLS:C0085271

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002222
(portability-ldpred2_self_harm_thoughts)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ever contemplated self-harm / Recent thoughts of suicide or self-harm Self-injurious behavior 761,279
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002222/ScoringFiles/PGS002222.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM012622 PGS002222
(portability-ldpred2_self_harm_thoughts)
 PSS009488|
European Ancestry|
6,459 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ever contemplated self-harm / Recent thoughts of suicide or self-harm — — Partial Correlation (partial-r): 0.0516 [0.0272, 0.076] sex, age, birth date, deprivation index, 16 PCs —
PPM012623 PGS002222
(portability-ldpred2_self_harm_thoughts)
 PSS009262|
European Ancestry|
1,242 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ever contemplated self-harm / Recent thoughts of suicide or self-harm — — Partial Correlation (partial-r): 0.0807 [0.0247, 0.1362] sex, age, birth date, deprivation index, 16 PCs —
PPM012624 PGS002222
(portability-ldpred2_self_harm_thoughts)
 PSS008816|
European Ancestry|
2,261 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ever contemplated self-harm / Recent thoughts of suicide or self-harm — — Partial Correlation (partial-r): 0.108 [0.0669, 0.1488] sex, age, birth date, deprivation index, 16 PCs —
PPM012626 PGS002222
(portability-ldpred2_self_harm_thoughts)
 PSS008368|
South Asian Ancestry|
818 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ever contemplated self-harm / Recent thoughts of suicide or self-harm — — Partial Correlation (partial-r): 0.0771 [0.0077, 0.1457] sex, age, birth date, deprivation index, 16 PCs —
PPM012627 PGS002222
(portability-ldpred2_self_harm_thoughts)
 PSS008144|
East Asian Ancestry|
428 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ever contemplated self-harm / Recent thoughts of suicide or self-harm — — Partial Correlation (partial-r): 0.063 [-0.0343, 0.1591] sex, age, birth date, deprivation index, 16 PCs —
PPM012628 PGS002222
(portability-ldpred2_self_harm_thoughts)
 PSS007932|
African Ancestry|
374 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ever contemplated self-harm / Recent thoughts of suicide or self-harm — — Partial Correlation (partial-r): 0.0884 [-0.0159, 0.1909] sex, age, birth date, deprivation index, 16 PCs —
PPM012629 PGS002222
(portability-ldpred2_self_harm_thoughts)
 PSS009036|
African Ancestry|
512 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ever contemplated self-harm / Recent thoughts of suicide or self-harm — — Partial Correlation (partial-r): -0.0688 [-0.1562, 0.0198] sex, age, birth date, deprivation index, 16 PCs —
PPM012625 PGS002222
(portability-ldpred2_self_harm_thoughts)
 PSS008590|
Greater Middle Eastern Ancestry|
203 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ever contemplated self-harm / Recent thoughts of suicide or self-harm — — Partial Correlation (partial-r): 0.1064 [-0.0392, 0.2477] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009036 — — 512 individuals — African unspecified Nigeria (West Africa) UKB —
PSS009262 — — 1,242 individuals — European Poland (NE Europe) UKB —
PSS008590 — — 203 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS008816 — — 2,261 individuals — European Italy (South Europe) UKB —
PSS008368 — — 818 individuals — South Asian India (South Asia) UKB —
PSS009488 — — 6,459 individuals — European UK (+ Ireland) UKB —
PSS008144 — — 428 individuals — East Asian China (East Asia) UKB —
PSS007932 — — 374 individuals — African American or Afro-Caribbean Carribean UKB —