Trait Information | |
Identifier | MONDO_0001056 |
Description | A primary or metastatic malignant neoplasm involving the stomach. [NCIT: C9331] | Trait categories |
Cancer
Digestive system disorder
|
Synonyms |
29 synonyms
|
Mapped terms |
11 mapped terms
|
Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
---|---|---|---|---|---|---|
PGS002299 (PRS3_gastric) |
PGP000328 | Choi J et al. Int J Cancer (2020) |
Gastric cancer | gastric cancer | 3 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002299/ScoringFiles/PGS002299.txt.gz |
PGS005161 (PRS-GC) |
PGP000711 | Zhu M et al. PLoS Med (2025) |
Stomach cancer | gastric cancer | 12 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005161/ScoringFiles/PGS005161.txt.gz |
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|---|
PPM013028 | PGS002299 (PRS3_gastric) |
PSS009662| European Ancestry| 272 individuals |
PGP000328 | Choi J et al. Int J Cancer (2020) |
Reported Trait: Gastric cancer | — | AUROC: 0.56 [0.54, 0.58] | — | — | — |
PPM013036 | PGS002299 (PRS3_gastric) |
PSS009662| European Ancestry| 272 individuals |
PGP000328 | Choi J et al. Int J Cancer (2020) |
Reported Trait: Gastric cancer | — | — | Hazard ratio (HR top 5% vs average): 1.27 [0.75, 2.15] | Age, birth cohort, genotyping array, top 10 PCs for ancestry and sex (for nonsex specific cancer only) | — |
PPM022398 | PGS005161 (PRS-GC) |
PSS011938| East Asian Ancestry| 100,219 individuals |
PGP000711 | Zhu M et al. PLoS Med (2025) |
Reported Trait: Stomach Cancer | HR: 1.27 [1.18, 1.38] β: 0.239 |
C-index: 0.572 | — | Age,Sex (if applicable),Region,Top 10 genetic ancestry principal components | The HR and C-index values were derived from Cox proportional hazards regression models. |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS011938 | ICD-10: C16 | Median = 11.33 years Range = [10.18, 12.26] years |
[ ,
42.8 % Male samples |
Mean = 53.69 years Sd = 11.01 years |
East Asian (Chinese) |
— | CKB | — |
PSS009662 | gastric cancer (ICD- 9 = 151 or ICD-10 = C16) | — | 272 individuals | — | European | — | UKB | — |