PGS Publication: PGP000487

Publication Information (EuropePMC)
Title Multi-ancestry genome-wide analysis identifies shared genetic effects and common genetic variants for self-reported sleep duration.
PubMed ID 37384397(Europe PMC)
doi 10.1093/hmg/ddad101
Publication Date June 29, 2023
Journal Hum Mol Genet
Author(s) Scammell BH, Tchio C, Song Y, Nishiyama T, Louie TL, Dashti HS, Nakatochi M, Zee PC, Daghlas I, Momozawa Y, Cai J, Ollila HM, Redline S, Wakai K, Sofer T, Suzuki S, Lane JM, Saxena R.
Released in PGS Catalog: Aug. 4, 2023

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003764
(PRS78_sleep duration)
 PGP000487 |
Scammell BH et al. Hum Mol Genet (2023)
 Sleep duration sleep duration 78
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003764/ScoringFiles/PGS003764.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM018565 PGS003764
(PRS78_sleep duration)
 PSS011028|
East Asian Ancestry|
13,618 individuals
 PGP000487 |
Scammell BH et al. Hum Mol Genet (2023)
 Reported Trait: sleep duration β: 0.38 [0.22, 0.54] — — — beta calculated as min/allele
PPM018566 PGS003764
(PRS78_sleep duration)
 PSS011027|
African Ancestry|
7,288 individuals
 PGP000487 |
Scammell BH et al. Hum Mol Genet (2023)
 Reported Trait: sleep duration β: 0.62 [0.41, 0.83] — — — beta calculated as min/allele
PPM018567 PGS003764
(PRS78_sleep duration)
 PSS011029|
South Asian Ancestry|
7,485 individuals
 PGP000487 |
Scammell BH et al. Hum Mol Genet (2023)
 Reported Trait: sleep duration β: 0.39 [0.04, 0.74] — — — beta calculated as min/allele

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011029 — — 7,485 individuals,
53.9 % Male samples
 Mean = 53.39 years
Sd = 8.46 years		 South Asian — UKB —
PSS011027 — — 7,288 individuals,
42.1 % Male samples
 Mean = 51.82 years
Sd = 8.06 years		 African unspecified — UKB —
PSS011028 — — 13,618 individuals,
45.3 % Male samples
 Mean = 54.6 years
Sd = 9.4 years		 East Asian — J-MICC —