| Publication Information (EuropePMC) | |
| Title | The sulfur microbial diet and increased risk of obesity: Findings from a population-based prospective cohort study. |
| PubMed ID | 37003050(Europe PMC) |
| doi | 10.1016/j.clnu.2023.03.011 |
| Publication Date | March 17, 2023 |
| Journal | Clin Nutr |
| Author(s) | Liu X, Wan X, Zhang L, Li Y, Ao Y, Zhuang P, Wu Y, Zhang Y, Jiao J. |
Polygenic Score ID & Name
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PGS Publication ID (PGP)
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Reported Trait
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Mapped Trait(s) (Ontology)
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Number of Variants
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Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link)
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|---|---|---|---|---|---|---|
| PGS003959 (GRS940_obesity) | PGP000507 | Liu X et al. Clin Nutr (2023) | Obesity | obesity | 940 | - | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003959/ScoringFiles/PGS003959.txt.gz |
PGS Performance Metric ID (PPM) |
Evaluated Score
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PGS Sample Set ID (PSS) |
Performance Source
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Trait
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PGS Effect Sizes (per SD change) |
Classification Metrics
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Other Metrics
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Covariates Included in the Model
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PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM019107 | PGS003959 (GRS940_obesity) | PSS011184| Multi-ancestry (including European)| 27,429 individuals | PGP000507 | Liu X et al. Clin Nutr (2023) | Reported Trait: Obesity | β: 0.149 (0.028) | — | — | Age, sex, race, centres, education, Townsend deprivation index, household income, smoking, alcohol c... onsumption, physical activity, sleep pattern, energy intake, and BMI, WC or BF% at baselineShow more | — |
| PPM019108 | PGS003959 (GRS940_obesity) | PSS011184| Multi-ancestry (including European)| 27,429 individuals | PGP000507 | Liu X et al. Clin Nutr (2023) | Reported Trait: Abdominal obesity | β: 0.078 (0.019) | — | — | Age, sex, race, centres, education, Townsend deprivation index, household income, smoking, alcohol c... onsumption, physical activity, sleep pattern, energy intake, and BMI, WC or BF% at baselineShow more | — |
| PPM019109 | PGS003959 (GRS940_obesity) | PSS011184| Multi-ancestry (including European)| 27,429 individuals | PGP000507 | Liu X et al. Clin Nutr (2023) | Reported Trait: Body mass index increase | β: 0.157 (0.013) | — | — | Age, sex, race, centres, education, Townsend deprivation index, household income, smoking, alcohol c... onsumption, physical activity, sleep pattern, energy intake, and BMI, WC or BF% at baselineShow more | — |
| PPM019110 | PGS003959 (GRS940_obesity) | PSS011184| Multi-ancestry (including European)| 27,429 individuals | PGP000507 | Liu X et al. Clin Nutr (2023) | Reported Trait: Wasit circumference increase | β: 0.213 (0.039) | — | — | Age, sex, race, centres, education, Townsend deprivation index, household income, smoking, alcohol c... onsumption, physical activity, sleep pattern, energy intake, and BMI, WC or BF% at baselineShow more | — |
| PPM019111 | PGS003959 (GRS940_obesity) | PSS011184| Multi-ancestry (including European)| 27,429 individuals | PGP000507 | Liu X et al. Clin Nutr (2023) | Reported Trait: Body fat percentage increase | β: 0.042 (0.021) | — | — | Age, sex, race, centres, education, Townsend deprivation index, household income, smoking, alcohol c... onsumption, physical activity, sleep pattern, energy intake, and BMI, WC or BF% at baselineShow more | — |
| PPM019112 | PGS003959 (GRS940_obesity) | PSS011184| Multi-ancestry (including European)| 27,429 individuals | PGP000507 | Liu X et al. Clin Nutr (2023) | Reported Trait: Obesity with sulfur microbial diet score | — | — | Hazard ratio (HR, Q4 sulphur microbial diet score and high PRS vs. Q1 sulphur microbial diet score and low PRS): 1.74 [1.33, 2.29] | age, sex, race, centers, household income, Townsend deprivation index, smoking, alcohol consumption,... physical activity, sleep pattern, energy intake and body mass index or waist circumstanceShow more | — |
| PPM019113 | PGS003959 (GRS940_obesity) | PSS011184| Multi-ancestry (including European)| 27,429 individuals | PGP000507 | Liu X et al. Clin Nutr (2023) | Reported Trait: Abdominal obesity with sulfur microbial diet score | — | — | Hazard ratio (HR, Q4 sulphur microbial diet score and high PRS vs. Q1 sulphur microbial diet score and low PRS): 1.41 [1.17, 1.71] | age, sex, race, centers, household income, Townsend deprivation index, smoking, alcohol consumption,... physical activity, sleep pattern, energy intake and body mass index or waist circumstanceShow more | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods
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Participant Follow-up Time
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Sample Numbers
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Age of Study Participants
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Sample Ancestry
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Additional Ancestry Description
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Cohort(s)
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Additional Sample/Cohort Information
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|---|---|---|---|---|---|---|---|---|
| PSS011184 | — | — | 27,429 individuals, 47.0 % Male samples | Mean = 55.3 years Sd = 7.6 years | European, Not reported | — | UKB | — |