PGS Publication: PGP000549

Publication Information (EuropePMC)
Title A Gene-Acculturation Study of Obesity Among US Hispanic/Latinos: The Hispanic Community Health Study/Study of Latinos.
PubMed ID 36917487(Europe PMC)
doi 10.1097/psy.0000000000001193
Publication Date March 15, 2023
Journal Psychosom Med
Author(s) Fernández-Rhodes L, McArdle CE, Rao H, Wang Y, Martinez-Miller EE, Ward JB, Cai J, Sofer T, Isasi CR, North KE.
Released in PGS Catalog: Jan. 11, 2024

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004319
(GRS103_BMI)
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Body mass index body mass index 103
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004319/ScoringFiles/PGS004319.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM020403 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index — — Beta (per effect allele): 0.34 — —
PPM020404 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index in females — — Beta (per effect allele): 0.37 — —
PPM020405 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index in males — — Beta (per effect allele): 0.27 — —
PPM020406 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index x SASH language use subscale interaction — — Beta (per effect allele): 0.17 (0.02) age, sex, top 5 principal components, and study site —
PPM020407 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index x SASH language use subscale interaction in females — — Beta (per effect allele): 0.15 (0.03) age, sex, top 5 principal components, and study site —
PPM020408 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index x SASH language use subscale interaction in males — — Beta (per effect allele): 0.22 (0.03) age, sex, top 5 principal components, and study site —
PPM020409 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index x nativity interaction — — Beta (per effect allele): 0.19 (0.03) age, sex, top 5 principal components, and study site —
PPM020410 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index x nativity interaction in females — — Beta (per effect allele): 0.23 (0.04) age, sex, top 5 principal components, and study site —
PPM020411 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index x nativity interaction in males — — Beta (per effect allele): 0.15 (0.03) age, sex, top 5 principal components, and study site —
PPM020412 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index x time in United States interaction — — Beta (per effect allele): 0.09 (0.01) age, sex, top 5 principal components, and study site —
PPM020413 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index x time in United States interaction in females — — Beta (per effect allele): 0.11 (0.01) age, sex, top 5 principal components, and study site —
PPM020414 PGS004319
(GRS103_BMI)
 PSS011351|
Hispanic or Latin American Ancestry|
11,747 individuals
 PGP000549 |
Fernández-Rhodes L et al. Psychosom Med (2023)
 Reported Trait: Body mass index x time in United States interaction in males — — Beta (per effect allele): 0.06 (0.01) age, sex, top 5 principal components, and study site —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011351 — — 11,747 individuals,
49.1 % Male samples
 Mean = 43.0 years Hispanic or Latin American — HCHS, SOL —