Predicted Trait | |
Reported Trait | Abnormal electrocardiogram |
Mapped Trait(s) | Abnormal EKG (HP_0003115) |
Score Construction | |
PGS Name | PRS6_EC |
Development Method | |
Name | Candidate SNPs significantly associated with an abnormal electrocardiogram |
Parameters | NR |
Variants | |
Original Genome Build | GRCh37 |
Number of Variants | 6 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000241 |
Citation (link to publication) | Wang M et al. Sci Rep (2021) |
Ancestry Distribution | |
Source of Variant Associations (GWAS) | East Asian: 100% 1,006 individuals (100%) |
PGS Evaluation | East Asian: 100% 1 Sample Sets |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) |
---|---|---|---|
GWAS Catalog: GCST012208 Europe PMC: 33633301 |
1,006 individuals | East Asian | NR |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM002983 | PSS001451| East Asian Ancestry| 100 individuals |
PGP000241 | Wang M et al. Sci Rep (2021) |
Reported Trait: Abnormal electrocardiogram | — | AUROC: 0.72 | Youden's index: 0.4 | Age, sex | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS001451 | — | — | 100 individuals | — | East Asian (Han Chinese) |
— | NR | — |