PGS Publication: PGP000241

Publication Information (EuropePMC)
Title A genome-wide association and polygenic risk score study on abnormal electrocardiogram in a Chinese population.
PubMed ID 33633301(Europe PMC)
doi 10.1038/s41598-021-84135-7
Publication Date Feb. 25, 2021
Journal Sci Rep
Author(s) Wang M, Gao J, Shi Y, Zhao X.
Released in PGS Catalog: Oct. 7, 2021

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
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Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000914
(PRS6_EC)
 PGP000241 |
Wang M et al. Sci Rep (2021)
 Abnormal electrocardiogram Abnormal EKG 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000914/ScoringFiles/PGS000914.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM002983 PGS000914
(PRS6_EC)
 PSS001451|
East Asian Ancestry|
100 individuals
 PGP000241 |
Wang M et al. Sci Rep (2021)
 Reported Trait: Abnormal electrocardiogram — AUROC: 0.72 Youden's index: 0.4 Age, sex —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS001451 — — 100 individuals — East Asian
(Han Chinese)		 — NR —