Predicted Trait | |
Reported Trait | Total cholesterol |
Mapped Trait(s) | total cholesterol measurement (EFO_0004574) |
Score Construction | |
PGS Name | TC_EAS_LDpred2 |
Development Method | |
Name | LDpred2 |
Parameters | causal SNPs protions vary with length 17 that are evened spaced on a logorithmic sale from 1E-04 to 1 |
Variants | |
Original Genome Build | GRCh37 |
Number of Variants | 820,996 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000489 |
Citation (link to publication) | Zhang H et al. Nat Genet (2023) |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) |
---|---|---|---|
GWAS Catalog: GCST90239649 Europe PMC: 34887591 |
146,492 individuals | East Asian | NR |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) | Phenotype Definitions & Methods | Age of Study Participants | Participant Follow-up Time | Additional Ancestry Description | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
— | 951 individuals, 32.0 % Male samples |
East Asian | UKB | — | Mean = 52.47 years Sd = 7.81 years |
— | — | — |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM018633 | PSS011048| East Asian Ancestry| 971 individuals |
PGP000489 | Zhang H et al. Nat Genet (2023) |
Reported Trait: Total cholesterol | — | — | R²: 0.07017 | — | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS011048 | — | — | 971 individuals, 32.0 % Male samples |
Mean = 52.47 years Sd = 7.81 years |
East Asian | — | UKB | — |