Polygenic Score (PGS) ID: PGS005121

Predicted Trait
Reported Trait Asthma
Mapped Trait(s) asthma (MONDO_0004979)
Released in PGS Catalog: Feb. 4, 2025
Download Score FTP directory
Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name forAFR_fromAFR
Development Method
Name PRS-CSx
Parameters NR
Variants
Original Genome Build GRCh37
Number of Variants 1,008,855
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000703
Citation (link to publication) Tsuo K et al. Cell Genom (2022)
Ancestry Distribution
Source of Variant
Associations (GWAS)
African: 100%
26,619 individuals (100%)
PGS Evaluation
African: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
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Study Identifiers
Sample Numbers
Sample Ancestry
Cohort(s)
[
  • 4,202 cases
  • , 22,417 controls
]
African unspecified6 cohorts
  • BioMe
  • ,BioVU
  • ,CCPM
  • ,MGI
  • ,UCLA
  • ,UKB
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM022341PSS011916|
African Ancestry|
6,039 individuals
PGP000703 |
Tsuo K et al. Cell Genom (2022)
Reported Trait: Asthma: 0.01355age, sex, 20 genetic principal components
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS011916
[
  • 849 cases
  • , 5,190 controls
]
African unspecifiedUKB
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