Trait: congestive heart failure

Experimental Factor Ontology (EFO) Information
Identifier EFO_0000373
Description Failure of the heart to pump a sufficient amount of blood to meet the needs of the body tissues, resulting in tissue congestion and edema. Signs and symptoms include shortness of breath, pitting edema, enlarged tender liver, engorged neck veins, and pulmonary rales. [NCIT: C3080]
Trait category
Cardiovascular disease
Synonyms 22 synonyms
  • CCF - Congestive cardiac failure
  • CHF
  • CHF - Congestive heart failure
  • CHF NOS
  • Cardiac Failure
  • Cardiac Failure Congestive
  • Congestive cardiac failure
  • Congestive heart disease
  • Congestive heart failure (disorder)
  • Congestive heart failure, unspecified
  • Congetive cardiac failure
  • Decompensation, Heart
  • FAILURE, CONGESTIVE HEART
  • Heart Decompensation
  • Heart Failure, Congestive
  • Myocardial Failure
  • cardiac failure, congestive
  • congestive heart disease
  • congestive heart failure
  • failure, congestive heart
  • heart failure, congestive
  • weak heart
Mapped terms 16 mapped terms
  • DOID:6000
  • ICD9:404.01
  • ICD9:404.11
  • ICD9:404.13
  • ICD9:428
  • ICD9:428.0
  • ICD9:428.9
  • MEDGEN:9169
  • MONDO:0005009
  • MedDRA:10010684
  • NCIT:C3080
  • NCIt:C3080
  • SCTID:42343007
  • SNOMEDCT:42343007
  • UMLS:C0018802
  • icd11.foundation:2136808878
Child trait(s) cor pulmonale

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "congestive heart failure" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001840
(portability-PLR_415)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Pulmonary heart disease cor pulmonale 330
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001840/ScoringFiles/PGS001840.txt.gz
PGS001842
(portability-PLR_428)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Congestive heart failure; nonhypertensive congestive heart failure 2,759
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001842/ScoringFiles/PGS001842.txt.gz
PGS002049
(portability-ldpred2_415)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Pulmonary heart disease cor pulmonale 222,371
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002049/ScoringFiles/PGS002049.txt.gz
PGS002051
(portability-ldpred2_428)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Congestive heart failure; nonhypertensive congestive heart failure 642,241
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002051/ScoringFiles/PGS002051.txt.gz
PGS005073
(Phe_428_1_ldpred_AFRss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005073/ScoringFiles/PGS005073.txt.gz
PGS005074
(Phe_428_1_ldpred_EURss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005074/ScoringFiles/PGS005074.txt.gz
PGS005075
(Phe_428_1_ldpred_HISss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005075/ScoringFiles/PGS005075.txt.gz
PGS005076
(Phe_428_1_ldpred_METAss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005076/ScoringFiles/PGS005076.txt.gz
PGS005077
(Phe_428_1_ldpred_METAss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005077/ScoringFiles/PGS005077.txt.gz
PGS005078
(Phe_428_1_ldpred_METAss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,286,612
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005078/ScoringFiles/PGS005078.txt.gz
PGS005079
(Phe_428_1_prscs_AFRss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,273,897
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005079/ScoringFiles/PGS005079.txt.gz
PGS005080
(Phe_428_1_prscs_EURss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,273,897
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005080/ScoringFiles/PGS005080.txt.gz
PGS005081
(Phe_428_1_prscs_HISss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,273,897
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005081/ScoringFiles/PGS005081.txt.gz
PGS005082
(Phe_428_1_prscs_METAss_afrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,273,897
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005082/ScoringFiles/PGS005082.txt.gz
PGS005083
(Phe_428_1_prscs_METAss_amrld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,273,897
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005083/ScoringFiles/PGS005083.txt.gz
PGS005084
(Phe_428_1_prscs_METAss_eurld)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,273,897
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005084/ScoringFiles/PGS005084.txt.gz
PGS005085
(Phe_428_1_prscsx_METAweight)
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Congestive heart failure (CHF), NOS (PheCode 428.1) congestive heart failure 1,256,161
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005085/ScoringFiles/PGS005085.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM009610 PGS001840
(portability-PLR_415)
 PSS009312|
European Ancestry|
19,808 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0355 [0.0216, 0.0494] sex, age, birth date, deprivation index, 16 PCs —
PPM009611 PGS001840
(portability-PLR_415)
 PSS009086|
European Ancestry|
4,113 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0647 [0.0341, 0.0952] sex, age, birth date, deprivation index, 16 PCs —
PPM009612 PGS001840
(portability-PLR_415)
 PSS008640|
European Ancestry|
6,617 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.038 [0.0139, 0.0621] sex, age, birth date, deprivation index, 16 PCs —
PPM009613 PGS001840
(portability-PLR_415)
 PSS008414|
Greater Middle Eastern Ancestry|
1,190 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): -0.0071 [-0.0643, 0.0503] sex, age, birth date, deprivation index, 16 PCs —
PPM009614 PGS001840
(portability-PLR_415)
 PSS008194|
South Asian Ancestry|
6,283 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.03 [0.0052, 0.0547] sex, age, birth date, deprivation index, 16 PCs —
PPM009615 PGS001840
(portability-PLR_415)
 PSS007976|
East Asian Ancestry|
1,805 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0109 [-0.0355, 0.0572] sex, age, birth date, deprivation index, 16 PCs —
PPM009616 PGS001840
(portability-PLR_415)
 PSS007759|
African Ancestry|
2,457 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0171 [-0.0226, 0.0568] sex, age, birth date, deprivation index, 16 PCs —
PPM009617 PGS001840
(portability-PLR_415)
 PSS008863|
African Ancestry|
3,858 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0366 [0.005, 0.0682] sex, age, birth date, deprivation index, 16 PCs —
PPM009626 PGS001842
(portability-PLR_428)
 PSS009314|
European Ancestry|
19,961 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0293 [0.0154, 0.0432] sex, age, birth date, deprivation index, 16 PCs —
PPM009627 PGS001842
(portability-PLR_428)
 PSS009088|
European Ancestry|
4,128 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0213 [-0.0093, 0.0519] sex, age, birth date, deprivation index, 16 PCs —
PPM009628 PGS001842
(portability-PLR_428)
 PSS008642|
European Ancestry|
6,648 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0227 [-0.0014, 0.0467] sex, age, birth date, deprivation index, 16 PCs —
PPM009629 PGS001842
(portability-PLR_428)
 PSS008416|
Greater Middle Eastern Ancestry|
1,197 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0369 [-0.0203, 0.0938] sex, age, birth date, deprivation index, 16 PCs —
PPM009631 PGS001842
(portability-PLR_428)
 PSS007978|
East Asian Ancestry|
1,808 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0692 [0.023, 0.1152] sex, age, birth date, deprivation index, 16 PCs —
PPM009632 PGS001842
(portability-PLR_428)
 PSS007761|
African Ancestry|
2,472 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0218 [-0.0178, 0.0613] sex, age, birth date, deprivation index, 16 PCs —
PPM009633 PGS001842
(portability-PLR_428)
 PSS008865|
African Ancestry|
3,905 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): -0.0133 [-0.0447, 0.0182] sex, age, birth date, deprivation index, 16 PCs —
PPM009630 PGS001842
(portability-PLR_428)
 PSS008196|
South Asian Ancestry|
6,294 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0004 [-0.0244, 0.0251] sex, age, birth date, deprivation index, 16 PCs —
PPM011254 PGS002049
(portability-ldpred2_415)
 PSS009312|
European Ancestry|
19,808 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0397 [0.0258, 0.0536] sex, age, birth date, deprivation index, 16 PCs —
PPM011255 PGS002049
(portability-ldpred2_415)
 PSS009086|
European Ancestry|
4,113 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0663 [0.0357, 0.0967] sex, age, birth date, deprivation index, 16 PCs —
PPM011256 PGS002049
(portability-ldpred2_415)
 PSS008640|
European Ancestry|
6,617 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0336 [0.0095, 0.0577] sex, age, birth date, deprivation index, 16 PCs —
PPM011257 PGS002049
(portability-ldpred2_415)
 PSS008414|
Greater Middle Eastern Ancestry|
1,190 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): -0.0019 [-0.0592, 0.0554] sex, age, birth date, deprivation index, 16 PCs —
PPM011258 PGS002049
(portability-ldpred2_415)
 PSS008194|
South Asian Ancestry|
6,283 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0331 [0.0083, 0.0578] sex, age, birth date, deprivation index, 16 PCs —
PPM011259 PGS002049
(portability-ldpred2_415)
 PSS007976|
East Asian Ancestry|
1,805 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0075 [-0.0389, 0.0539] sex, age, birth date, deprivation index, 16 PCs —
PPM011260 PGS002049
(portability-ldpred2_415)
 PSS007759|
African Ancestry|
2,457 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.014 [-0.0257, 0.0537] sex, age, birth date, deprivation index, 16 PCs —
PPM011261 PGS002049
(portability-ldpred2_415)
 PSS008863|
African Ancestry|
3,858 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Pulmonary heart disease — — Partial Correlation (partial-r): 0.0322 sex, age, birth date, deprivation index, 16 PCs —
PPM011270 PGS002051
(portability-ldpred2_428)
 PSS009314|
European Ancestry|
19,961 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0235 [0.0097, 0.0374] sex, age, birth date, deprivation index, 16 PCs —
PPM011271 PGS002051
(portability-ldpred2_428)
 PSS009088|
European Ancestry|
4,128 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0368 [0.0062, 0.0673] sex, age, birth date, deprivation index, 16 PCs —
PPM011272 PGS002051
(portability-ldpred2_428)
 PSS008642|
European Ancestry|
6,648 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0327 [0.0086, 0.0567] sex, age, birth date, deprivation index, 16 PCs —
PPM011274 PGS002051
(portability-ldpred2_428)
 PSS008196|
South Asian Ancestry|
6,294 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0021 [-0.0226, 0.0269] sex, age, birth date, deprivation index, 16 PCs —
PPM011275 PGS002051
(portability-ldpred2_428)
 PSS007978|
East Asian Ancestry|
1,808 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0376 [-0.0087, 0.0838] sex, age, birth date, deprivation index, 16 PCs —
PPM011276 PGS002051
(portability-ldpred2_428)
 PSS007761|
African Ancestry|
2,472 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.025 [-0.0146, 0.0645] sex, age, birth date, deprivation index, 16 PCs —
PPM011277 PGS002051
(portability-ldpred2_428)
 PSS008865|
African Ancestry|
3,905 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): 0.0121 [-0.0193, 0.0436] sex, age, birth date, deprivation index, 16 PCs —
PPM011273 PGS002051
(portability-ldpred2_428)
 PSS008416|
Greater Middle Eastern Ancestry|
1,197 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Congestive heart failure; nonhypertensive — — Partial Correlation (partial-r): -0.0001 [-0.0572, 0.0571] sex, age, birth date, deprivation index, 16 PCs —
PPM021956 PGS005073
(Phe_428_1_ldpred_AFRss_afrld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.139 [1.01, 1.29] C-index: 0.79007 — age, sex, 20 PCs —
PPM021962 PGS005073
(Phe_428_1_ldpred_AFRss_afrld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.128 [1.07, 1.19] C-index: 0.74096 — age, sex, 20 PCs —
PPM021968 PGS005073
(Phe_428_1_ldpred_AFRss_afrld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.22 [1.12, 1.33] C-index: 0.71526 — age, sex, 20 PCs —
PPM021958 PGS005074
(Phe_428_1_ldpred_EURss_eurld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.386 [1.14, 1.68] C-index: 0.79052 — age, sex, 20 PCs —
PPM021964 PGS005074
(Phe_428_1_ldpred_EURss_eurld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.427 [1.35, 1.51] C-index: 0.75177 — age, sex, 20 PCs —
PPM021970 PGS005074
(Phe_428_1_ldpred_EURss_eurld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.291 [1.11, 1.5] C-index: 0.71208 — age, sex, 20 PCs —
PPM021957 PGS005075
(Phe_428_1_ldpred_HISss_amrld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.052 [0.92, 1.2] C-index: 0.78786 — age, sex, 20 PCs —
PPM021963 PGS005075
(Phe_428_1_ldpred_HISss_amrld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.095 [1.04, 1.15] C-index: 0.73981 — age, sex, 20 PCs —
PPM021969 PGS005075
(Phe_428_1_ldpred_HISss_amrld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.089 [1.0, 1.19] C-index: 0.70971 — age, sex, 20 PCs —
PPM021953 PGS005076
(Phe_428_1_ldpred_METAss_afrld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.354 [1.17, 1.57] C-index: 0.79231 — age, sex, 20 PCs —
PPM021965 PGS005076
(Phe_428_1_ldpred_METAss_afrld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.369 [1.23, 1.52] C-index: 0.71935 — age, sex, 20 PCs —
PPM021959 PGS005076
(Phe_428_1_ldpred_METAss_afrld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.443 [1.37, 1.52] C-index: 0.75325 — age, sex, 20 PCs —
PPM021954 PGS005077
(Phe_428_1_ldpred_METAss_amrld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.315 [1.14, 1.52] C-index: 0.7917 — age, sex, 20 PCs —
PPM021960 PGS005077
(Phe_428_1_ldpred_METAss_amrld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.452 [1.38, 1.53] C-index: 0.75358 — age, sex, 20 PCs —
PPM021966 PGS005077
(Phe_428_1_ldpred_METAss_amrld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.37 [1.24, 1.52] C-index: 0.7197 — age, sex, 20 PCs —
PPM021955 PGS005078
(Phe_428_1_ldpred_METAss_eurld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.371 [1.18, 1.59] C-index: 0.79286 — age, sex, 20 PCs —
PPM021961 PGS005078
(Phe_428_1_ldpred_METAss_eurld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.442 [1.37, 1.52] C-index: 0.75253 — age, sex, 20 PCs —
PPM021967 PGS005078
(Phe_428_1_ldpred_METAss_eurld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.38 [1.24, 1.54] C-index: 0.71824 — age, sex, 20 PCs —
PPM021870 PGS005079
(Phe_428_1_prscs_AFRss_afrld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.127 [1.07, 1.19] C-index: 0.7408 — age, sex, 20 PCs —
PPM021863 PGS005079
(Phe_428_1_prscs_AFRss_afrld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.098 [0.97, 1.24] C-index: 0.78907 — age, sex, 20 PCs —
PPM021877 PGS005079
(Phe_428_1_prscs_AFRss_afrld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.24 [1.13, 1.36] C-index: 0.71475 — age, sex, 20 PCs —
PPM021872 PGS005080
(Phe_428_1_prscs_EURss_eurld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.44 [1.37, 1.52] C-index: 0.75317 — age, sex, 20 PCs —
PPM021865 PGS005080
(Phe_428_1_prscs_EURss_eurld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.364 [1.15, 1.62] C-index: 0.79082 — age, sex, 20 PCs —
PPM021879 PGS005080
(Phe_428_1_prscs_EURss_eurld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.287 [1.13, 1.47] C-index: 0.71297 — age, sex, 20 PCs —
PPM021871 PGS005081
(Phe_428_1_prscs_HISss_amrld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.09 [1.04, 1.15] C-index: 0.73963 — age, sex, 20 PCs —
PPM021864 PGS005081
(Phe_428_1_prscs_HISss_amrld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.033 [0.91, 1.18] C-index: 0.78774 — age, sex, 20 PCs —
PPM021878 PGS005081
(Phe_428_1_prscs_HISss_amrld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.07 [0.98, 1.17] C-index: 0.70939 — age, sex, 20 PCs —
PPM021867 PGS005082
(Phe_428_1_prscs_METAss_afrld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.39 [1.32, 1.47] C-index: 0.75065 — age, sex, 20 PCs —
PPM021874 PGS005082
(Phe_428_1_prscs_METAss_afrld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.317 [1.19, 1.46] C-index: 0.7165 — age, sex, 20 PCs —
PPM021860 PGS005082
(Phe_428_1_prscs_METAss_afrld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.31 [1.14, 1.5] C-index: 0.79176 — age, sex, 20 PCs —
PPM021861 PGS005083
(Phe_428_1_prscs_METAss_amrld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.319 [1.14, 1.53] C-index: 0.79127 — age, sex, 20 PCs —
PPM021868 PGS005083
(Phe_428_1_prscs_METAss_amrld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.455 [1.38, 1.54] C-index: 0.75368 — age, sex, 20 PCs —
PPM021875 PGS005083
(Phe_428_1_prscs_METAss_amrld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.314 [1.18, 1.46] C-index: 0.71674 — age, sex, 20 PCs —
PPM021862 PGS005084
(Phe_428_1_prscs_METAss_eurld)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.396 [1.2, 1.62] C-index: 0.79297 — age, sex, 20 PCs —
PPM021876 PGS005084
(Phe_428_1_prscs_METAss_eurld)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.385 [1.24, 1.54] C-index: 0.71868 — age, sex, 20 PCs —
PPM021869 PGS005084
(Phe_428_1_prscs_METAss_eurld)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.45 [1.37, 1.53] C-index: 0.75272 — age, sex, 20 PCs —
PPM021866 PGS005085
(Phe_428_1_prscsx_METAweight)
 PSS011811|
Hispanic or Latin American Ancestry|
8,119 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.303 [1.14, 1.49] C-index: 0.79251 — age, sex, 20 PCs —
PPM021873 PGS005085
(Phe_428_1_prscsx_METAweight)
 PSS011821|
European Ancestry|
31,804 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.437 [1.36, 1.51] C-index: 0.7528 — age, sex, 20 PCs —
PPM021880 PGS005085
(Phe_428_1_prscsx_METAweight)
 PSS011801|
African Ancestry|
10,682 individuals
 PGP000679 |
Gunn S et al. HGG Adv (2024)
 Reported Trait: Congestive heart failure (CHF), NOS OR: 1.333 [1.21, 1.47] C-index: 0.71878 — age, sex, 20 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007759 — — 2,457 individuals — African American or Afro-Caribbean Carribean UKB —
PSS007761 — — 2,472 individuals — African American or Afro-Caribbean Carribean UKB —
PSS008414 — — 1,190 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009312 — — 19,808 individuals — European UK (+ Ireland) UKB —
PSS008416 — — 1,197 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009314 — — 19,961 individuals — European UK (+ Ireland) UKB —
PSS008640 — — 6,617 individuals — European Italy (South Europe) UKB —
PSS009086 — — 4,113 individuals — European Poland (NE Europe) UKB —
PSS009088 — — 4,128 individuals — European Poland (NE Europe) UKB —
PSS008194 — — 6,283 individuals — South Asian India (South Asia) UKB —
PSS008196 — — 6,294 individuals — South Asian India (South Asia) UKB —
PSS008863 — — 3,858 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008865 — — 3,905 individuals — African unspecified Nigeria (West Africa) UKB —
PSS007976 — — 1,805 individuals — East Asian China (East Asia) UKB —
PSS007978 — — 1,808 individuals — East Asian China (East Asia) UKB —
PSS011801 — —
[
  • 741 cases
  • , 9,941 controls
]
 — African American or Afro-Caribbean — AllofUs —
PSS011811 — —
[
  • 315 cases
  • , 7,804 controls
]
 — Hispanic or Latin American — AllofUs —
PSS011821 — —
[
  • 1,687 cases
  • , 30,117 controls
]
 — European — AllofUs —
PSS008642 — — 6,648 individuals — European Italy (South Europe) UKB —