| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0004584 |
| Description | A measurement of mean platelet volume is a machine-calculated measurement of the average size of platelets found in blood | Trait category |
Hematological measurement
|
| Mapped terms |
2 mapped terms
|
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS000104 (mpv) |
PGP000051 | Xu Y et al. Cell Genom (2022) |
Mean platelet volume | mean platelet volume | 25,745 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000104/ScoringFiles/PGS000104.txt.gz | |
| PGS000179 (mpv) |
PGP000078 | Vuckovic D et al. Cell (2020) |
Mean platelet volume | mean platelet volume | 654 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000179/ScoringFiles/PGS000179.txt.gz |
| PGS001200 (GBE_INI30100) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Mean platelet volume | mean platelet volume | 24,114 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001200/ScoringFiles/PGS001200.txt.gz |
| PGS001971 (portability-PLR_log_platelet_volume) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Mean platelet (thrombocyte) volume | mean platelet volume | 65,450 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001971/ScoringFiles/PGS001971.txt.gz |
| PGS002189 (portability-ldpred2_log_platelet_volume) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Mean platelet (thrombocyte) volume | mean platelet volume | 462,934 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002189/ScoringFiles/PGS002189.txt.gz |
| PGS002340 (blood_MEAN_PLATELET_VOL.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Mean platelet volume | mean platelet volume | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002340/ScoringFiles/PGS002340.txt.gz |
| PGS002412 (blood_MEAN_PLATELET_VOL.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Mean platelet volume | mean platelet volume | 36,285 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002412/ScoringFiles/PGS002412.txt.gz |
| PGS002461 (blood_MEAN_PLATELET_VOL.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Mean platelet volume | mean platelet volume | 65,237 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002461/ScoringFiles/PGS002461.txt.gz |
| PGS002510 (blood_MEAN_PLATELET_VOL.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Mean platelet volume | mean platelet volume | 183,887 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002510/ScoringFiles/PGS002510.txt.gz |
| PGS002559 (blood_MEAN_PLATELET_VOL.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Mean platelet volume | mean platelet volume | 19,124 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002559/ScoringFiles/PGS002559.txt.gz |
| PGS002608 (blood_MEAN_PLATELET_VOL.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Mean platelet volume | mean platelet volume | 14,380 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002608/ScoringFiles/PGS002608.txt.gz |
| PGS002657 (blood_MEAN_PLATELET_VOL.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Mean platelet volume | mean platelet volume | 354,280 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002657/ScoringFiles/PGS002657.txt.gz |
| PGS002706 (blood_MEAN_PLATELET_VOL.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Mean platelet volume | mean platelet volume | 973,986 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002706/ScoringFiles/PGS002706.txt.gz |
| PGS003548 (cont-decay-log_platelet_volume) |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Mean platelet (thrombocyte) volume | mean platelet volume | 979,739 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003548/ScoringFiles/PGS003548.txt.gz |
| PGS003934 (INI30100) |
PGP000502 | Tanigawa Y et al. AJHG (2023) |
Mean platelet (thrombocyte) volume | mean platelet volume | 31,032 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003934/ScoringFiles/PGS003934.txt.gz |
| PGS004354 (X30100.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
Mean platelet (thrombocyte) volume | mean platelet volume | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004354/ScoringFiles/PGS004354.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM000240 | PGS000104 (mpv) |
PSS000169| European Ancestry| 78,320 individuals |
PGP000051 | Xu Y et al. Cell Genom (2022) |
Reported Trait: Mean platelet volume | — | — | Pearson correlation coefficent (r): 0.61214 | age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment) | UKB Testing Set - these samples were held out from Score Development (regression training) but overlap with the samples used for variant selection (GWAS) |
| PPM000241 | PGS000104 (mpv) |
PSS000143| European Ancestry| 37,224 individuals |
PGP000051 | Xu Y et al. Cell Genom (2022) |
Reported Trait: Mean platelet volume | — | — | Pearson correlation coefficent (r): 0.60875 | age, sex, 10 PCs of ancestry, lifestyle factors (diet, smoking, alcohol consumption), technical covariates (the time between venepuncture and full blood cell analysis, seasonal effects, centre of sample collection, time dependent drift of equipment, systematic differences in equipment) | — |
| PPM000555 | PGS000179 (mpv) |
PSS000290| European Ancestry| 2,314 individuals |
PGP000078 | Vuckovic D et al. Cell (2020) |
Reported Trait: Mean platelet volume | — | — | R²: 0.19379 | sex, age, 10 genetic PCs | — |
| PPM000535 | PGS000179 (mpv) |
PSS000291| European Ancestry| 39,260 individuals |
PGP000078 | Vuckovic D et al. Cell (2020) |
Reported Trait: Mean platelet volume | — | — | R²: 0.27306 | sex, age, 10 genetic PCs | — |
| PPM001776 | PGS000179 (mpv) |
PSS000911| Greater Middle Eastern Ancestry| 13,989 individuals |
PGP000147 | Thareja G et al. Nat Commun (2021) |Ext. |
Reported Trait: Mean platelet volume | — | — | Pearson correlation coefficent (r): 0.51 | — | — |
| PPM008619 | PGS001200 (GBE_INI30100) |
PSS006956| African Ancestry| 6,139 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean platelet volume | — | — | R²: 0.11523 [0.10064, 0.12983] Incremental R2 (full-covars): 0.10713 PGS R2 (no covariates): 0.10764 [0.09341, 0.12187] |
age, sex, UKB array type, Genotype PCs | — |
| PPM008620 | PGS001200 (GBE_INI30100) |
PSS006957| East Asian Ancestry| 1,655 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean platelet volume | — | — | R²: 0.22982 [0.19483, 0.26481] Incremental R2 (full-covars): 0.1912 PGS R2 (no covariates): 0.20572 [0.17158, 0.23986] |
age, sex, UKB array type, Genotype PCs | — |
| PPM008621 | PGS001200 (GBE_INI30100) |
PSS006958| European Ancestry| 24,175 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean platelet volume | — | — | R²: 0.36048 [0.35094, 0.37001] Incremental R2 (full-covars): 0.35332 PGS R2 (no covariates): 0.3577 [0.34816, 0.36724] |
age, sex, UKB array type, Genotype PCs | — |
| PPM008622 | PGS001200 (GBE_INI30100) |
PSS006959| South Asian Ancestry| 7,520 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean platelet volume | — | — | R²: 0.26489 [0.24813, 0.28164] Incremental R2 (full-covars): 0.25606 PGS R2 (no covariates): 0.25974 [0.24303, 0.27644] |
age, sex, UKB array type, Genotype PCs | — |
| PPM008623 | PGS001200 (GBE_INI30100) |
PSS006960| European Ancestry| 65,636 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean platelet volume | — | — | R²: 0.36177 [0.35598, 0.36757] Incremental R2 (full-covars): 0.35994 PGS R2 (no covariates): 0.36024 [0.35444, 0.36603] |
age, sex, UKB array type, Genotype PCs | — |
| PPM010643 | PGS001971 (portability-PLR_log_platelet_volume) |
PSS009461| European Ancestry| 19,423 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.6032 [0.5942, 0.6121] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010644 | PGS001971 (portability-PLR_log_platelet_volume) |
PSS009235| European Ancestry| 4,002 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.6067 [0.5867, 0.626] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010645 | PGS001971 (portability-PLR_log_platelet_volume) |
PSS008789| European Ancestry| 6,437 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.5713 [0.5546, 0.5875] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010646 | PGS001971 (portability-PLR_log_platelet_volume) |
PSS008563| Greater Middle Eastern Ancestry| 1,153 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.5283 [0.485, 0.5691] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010647 | PGS001971 (portability-PLR_log_platelet_volume) |
PSS008341| South Asian Ancestry| 6,078 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.5282 [0.5098, 0.5461] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010648 | PGS001971 (portability-PLR_log_platelet_volume) |
PSS008118| East Asian Ancestry| 1,762 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.4452 [0.4067, 0.4821] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010649 | PGS001971 (portability-PLR_log_platelet_volume) |
PSS007905| African Ancestry| 2,343 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.3353 [0.2987, 0.3709] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010650 | PGS001971 (portability-PLR_log_platelet_volume) |
PSS009009| African Ancestry| 3,711 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.3125 [0.2831, 0.3414] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012359 | PGS002189 (portability-ldpred2_log_platelet_volume) |
PSS009461| European Ancestry| 19,423 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.5923 [0.5831, 0.6013] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012360 | PGS002189 (portability-ldpred2_log_platelet_volume) |
PSS009235| European Ancestry| 4,002 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.5914 [0.5709, 0.6113] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012361 | PGS002189 (portability-ldpred2_log_platelet_volume) |
PSS008789| European Ancestry| 6,437 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.5603 [0.5433, 0.5769] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012362 | PGS002189 (portability-ldpred2_log_platelet_volume) |
PSS008563| Greater Middle Eastern Ancestry| 1,153 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.5196 [0.4758, 0.5609] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012363 | PGS002189 (portability-ldpred2_log_platelet_volume) |
PSS008341| South Asian Ancestry| 6,078 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.5166 [0.4979, 0.5348] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012364 | PGS002189 (portability-ldpred2_log_platelet_volume) |
PSS008118| East Asian Ancestry| 1,762 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.444 [0.4054, 0.4809] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012365 | PGS002189 (portability-ldpred2_log_platelet_volume) |
PSS007905| African Ancestry| 2,343 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.3231 [0.2862, 0.3591] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012366 | PGS002189 (portability-ldpred2_log_platelet_volume) |
PSS009009| African Ancestry| 3,711 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | Partial Correlation (partial-r): 0.2907 [0.2609, 0.3199] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM013105 | PGS002340 (blood_MEAN_PLATELET_VOL.BOLT-LMM) |
PSS009803| African Ancestry| 6,153 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1049 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013154 | PGS002340 (blood_MEAN_PLATELET_VOL.BOLT-LMM) |
PSS009804| East Asian Ancestry| 892 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1872 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013203 | PGS002340 (blood_MEAN_PLATELET_VOL.BOLT-LMM) |
PSS009805| European Ancestry| 42,078 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.3575 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013252 | PGS002340 (blood_MEAN_PLATELET_VOL.BOLT-LMM) |
PSS009806| South Asian Ancestry| 7,770 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.259 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013393 | PGS002412 (blood_MEAN_PLATELET_VOL.P+T.0.0001) |
PSS009803| African Ancestry| 6,153 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.0202 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013442 | PGS002412 (blood_MEAN_PLATELET_VOL.P+T.0.0001) |
PSS009804| East Asian Ancestry| 892 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1256 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013491 | PGS002412 (blood_MEAN_PLATELET_VOL.P+T.0.0001) |
PSS009805| European Ancestry| 42,078 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.2484 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013540 | PGS002412 (blood_MEAN_PLATELET_VOL.P+T.0.0001) |
PSS009806| South Asian Ancestry| 7,770 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1677 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013638 | PGS002461 (blood_MEAN_PLATELET_VOL.P+T.0.001) |
PSS009804| East Asian Ancestry| 892 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1171 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013687 | PGS002461 (blood_MEAN_PLATELET_VOL.P+T.0.001) |
PSS009805| European Ancestry| 42,078 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.2478 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013736 | PGS002461 (blood_MEAN_PLATELET_VOL.P+T.0.001) |
PSS009806| South Asian Ancestry| 7,770 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1579 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013589 | PGS002461 (blood_MEAN_PLATELET_VOL.P+T.0.001) |
PSS009803| African Ancestry| 6,153 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.0039 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013785 | PGS002510 (blood_MEAN_PLATELET_VOL.P+T.0.01) |
PSS009803| African Ancestry| 6,153 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.0014 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013834 | PGS002510 (blood_MEAN_PLATELET_VOL.P+T.0.01) |
PSS009804| East Asian Ancestry| 892 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.0417 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013883 | PGS002510 (blood_MEAN_PLATELET_VOL.P+T.0.01) |
PSS009805| European Ancestry| 42,078 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1998 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013932 | PGS002510 (blood_MEAN_PLATELET_VOL.P+T.0.01) |
PSS009806| South Asian Ancestry| 7,770 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.0686 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013981 | PGS002559 (blood_MEAN_PLATELET_VOL.P+T.1e-06) |
PSS009803| African Ancestry| 6,153 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.0539 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014030 | PGS002559 (blood_MEAN_PLATELET_VOL.P+T.1e-06) |
PSS009804| East Asian Ancestry| 892 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.114 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014079 | PGS002559 (blood_MEAN_PLATELET_VOL.P+T.1e-06) |
PSS009805| European Ancestry| 42,078 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.2375 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014128 | PGS002559 (blood_MEAN_PLATELET_VOL.P+T.1e-06) |
PSS009806| South Asian Ancestry| 7,770 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1648 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014177 | PGS002608 (blood_MEAN_PLATELET_VOL.P+T.5e-08) |
PSS009803| African Ancestry| 6,153 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.0528 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014226 | PGS002608 (blood_MEAN_PLATELET_VOL.P+T.5e-08) |
PSS009804| East Asian Ancestry| 892 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1077 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014275 | PGS002608 (blood_MEAN_PLATELET_VOL.P+T.5e-08) |
PSS009805| European Ancestry| 42,078 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.2311 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014324 | PGS002608 (blood_MEAN_PLATELET_VOL.P+T.5e-08) |
PSS009806| South Asian Ancestry| 7,770 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1619 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014373 | PGS002657 (blood_MEAN_PLATELET_VOL.PolyFun-pred) |
PSS009803| African Ancestry| 6,153 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.1611 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See blood_MEAN_PLATELET_VOL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014422 | PGS002657 (blood_MEAN_PLATELET_VOL.PolyFun-pred) |
PSS009804| East Asian Ancestry| 892 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.2269 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See blood_MEAN_PLATELET_VOL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014471 | PGS002657 (blood_MEAN_PLATELET_VOL.PolyFun-pred) |
PSS009805| European Ancestry| 42,078 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.3972 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See blood_MEAN_PLATELET_VOL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014520 | PGS002657 (blood_MEAN_PLATELET_VOL.PolyFun-pred) |
PSS009806| South Asian Ancestry| 7,770 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.2957 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See blood_MEAN_PLATELET_VOL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014569 | PGS002706 (blood_MEAN_PLATELET_VOL.SBayesR) |
PSS009803| African Ancestry| 6,153 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1127 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014618 | PGS002706 (blood_MEAN_PLATELET_VOL.SBayesR) |
PSS009804| East Asian Ancestry| 892 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.1723 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014667 | PGS002706 (blood_MEAN_PLATELET_VOL.SBayesR) |
PSS009805| European Ancestry| 42,078 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.3475 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014716 | PGS002706 (blood_MEAN_PLATELET_VOL.SBayesR) |
PSS009806| South Asian Ancestry| 7,770 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Mean Platelet Volume | — | — | Incremental R2 (full model vs. covariates alone): 0.2571 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM017560 | PGS003548 (cont-decay-log_platelet_volume) |
PSS010829| European Ancestry| 3,991 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | partial-R2: 0.35 | sex, age, deprivation index, PC1-16 | — |
| PPM017644 | PGS003548 (cont-decay-log_platelet_volume) |
PSS010661| European Ancestry| 6,278 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | partial-R2: 0.31 | sex, age, deprivation index, PC1-16 | — |
| PPM017812 | PGS003548 (cont-decay-log_platelet_volume) |
PSS010241| European Ancestry| 2,264 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | partial-R2: 0.28 | sex, age, deprivation index, PC1-16 | — |
| PPM017896 | PGS003548 (cont-decay-log_platelet_volume) |
PSS010493| South Asian Ancestry| 6,026 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | partial-R2: 0.26 | sex, age, deprivation index, PC1-16 | — |
| PPM017980 | PGS003548 (cont-decay-log_platelet_volume) |
PSS010409| East Asian Ancestry| 1,750 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | partial-R2: 0.19 | sex, age, deprivation index, PC1-16 | — |
| PPM018064 | PGS003548 (cont-decay-log_platelet_volume) |
PSS010325| African Ancestry| 2,330 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | partial-R2: 0.1 | sex, age, deprivation index, PC1-16 | — |
| PPM018148 | PGS003548 (cont-decay-log_platelet_volume) |
PSS010745| African Ancestry| 3,682 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | partial-R2: 0.09 | sex, age, deprivation index, PC1-16 | — |
| PPM017476 | PGS003548 (cont-decay-log_platelet_volume) |
PSS010913| European Ancestry| 19,418 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | partial-R2: 0.34 | sex, age, deprivation index, PC1-16 | — |
| PPM017728 | PGS003548 (cont-decay-log_platelet_volume) |
PSS010577| Greater Middle Eastern Ancestry| 1,123 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | partial-R2: 0.26 | sex, age, deprivation index, PC1-16 | — |
| PPM018989 | PGS003934 (INI30100) |
PSS011144| European Ancestry| 65,930 individuals |
PGP000502 | Tanigawa Y et al. AJHG (2023) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | R²: 0.36086 [0.35507, 0.36664] PGS R2 (no covariates): 0.35829 [0.35251, 0.36408] Incremental R2 (full-covars): 0.35783 |
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) | — |
| PPM018990 | PGS003934 (INI30100) |
PSS011109| European Ancestry| 2,813 individuals |
PGP000502 | Tanigawa Y et al. AJHG (2023) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | R²: 0.36427 [0.33635, 0.3922] PGS R2 (no covariates): 0.35942 [0.33147, 0.38737] Incremental R2 (full-covars): 0.35587 |
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) | — |
| PPM018991 | PGS003934 (INI30100) |
PSS011113| South Asian Ancestry| 1,433 individuals |
PGP000502 | Tanigawa Y et al. AJHG (2023) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | R²: 0.2322 [0.19468, 0.26972] PGS R2 (no covariates): 0.23172 [0.19421, 0.26922] Incremental R2 (full-covars): 0.22951 |
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) | — |
| PPM018993 | PGS003934 (INI30100) |
PSS011166| Multi-ancestry (excluding European)| 7,746 individuals |
PGP000502 | Tanigawa Y et al. AJHG (2023) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | R²: 0.30944 [0.29261, 0.32626] PGS R2 (no covariates): 0.31539 [0.29855, 0.33222] Incremental R2 (full-covars): 0.2903 |
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) | — |
| PPM018992 | PGS003934 (INI30100) |
PSS011155| African Ancestry| 1,157 individuals |
PGP000502 | Tanigawa Y et al. AJHG (2023) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | R²: 0.10997 [0.07685, 0.1431] PGS R2 (no covariates): 0.10936 [0.0763, 0.14241] Incremental R2 (full-covars): 0.10916 |
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) | — |
| PPM020469 | PGS004354 (X30100.score) |
PSS011364| European Ancestry| 56,192 individuals |
PGP000561 | Jung H et al. Commun Biol (2024) |
Reported Trait: Mean platelet (thrombocyte) volume | — | — | PGS R2 (no covariates): 0.39954 | — | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS010913 | — | — | 19,418 individuals, 46.0 % Male samples |
Mean = 56.9 years Sd = 7.9 years |
European | white British | UKB | — |
| PSS011144 | — | — | 65,930 individuals | — | European (white British ancestry) |
— | UKB | — |
| PSS010661 | — | — | 6,278 individuals, 45.0 % Male samples |
Mean = 54.5 years Sd = 8.4 years |
European | Italian | UKB | — |
| PSS010409 | — | — | 1,750 individuals, 33.0 % Male samples |
Mean = 52.5 years Sd = 7.8 years |
East Asian | Chinese | UKB | — |
| PSS011155 | — | — | 1,157 individuals | — | African unspecified | — | UKB | — |
| PSS008789 | — | — | 6,437 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS011166 | — | — | 7,746 individuals | — | East Asian, Other admixed ancestry | East Asian, Other admixed ancestry | UKB | — |
| PSS007905 | — | — | 2,343 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS000290 | — | — | 2,314 individuals | — | European (French Canadian) |
— | CARTaGENE | — |
| PSS000291 | — | — | 39,260 individuals | — | European | — | INTERVAL | — |
| PSS008563 | — | — | 1,153 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS000911 | — | — | 13,989 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) (Qatari) |
— | QBB | — |
| PSS009461 | — | — | 19,423 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS010829 | — | — | 3,991 individuals, 38.0 % Male samples |
Mean = 54.3 years Sd = 7.5 years |
European | Polish | UKB | — |
| PSS010577 | — | — | 1,123 individuals, 59.0 % Male samples |
Mean = 52.0 years Sd = 8.0 years |
Greater Middle Eastern (Middle Eastern, North African or Persian) | Iranian | UKB | — |
| PSS010325 | — | — | 2,330 individuals, 37.0 % Male samples |
Mean = 52.4 years Sd = 8.0 years |
African American or Afro-Caribbean | Caribbean | UKB | — |
| PSS009803 | — | — | 6,153 individuals | — | African unspecified | — | UKB | — |
| PSS009804 | — | — | 892 individuals | — | East Asian | — | UKB | — |
| PSS009805 | — | — | 42,078 individuals | — | European | Non-British European | UKB | — |
| PSS009806 | — | — | 7,770 individuals | — | South Asian | — | UKB | — |
| PSS000143 | — | — | 37,224 individuals, 50.0 % Male samples |
Mean = 43.8 years Range = [18.0, 75.7] years |
European | — | INTERVAL | — |
| PSS009235 | — | — | 4,002 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS008341 | — | — | 6,078 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS010745 | — | — | 3,682 individuals, 47.0 % Male samples |
Mean = 51.9 years Sd = 8.1 years |
African unspecified | Nigerian | UKB | — |
| PSS011364 | — | — | 56,192 individuals | — | European | — | UKB | — |
| PSS010493 | — | — | 6,026 individuals, 55.0 % Male samples |
Mean = 53.3 years Sd = 8.4 years |
South Asian | Indian | UKB | — |
| PSS011109 | — | — | 2,813 individuals | — | European (non-white British ancestry) |
— | UKB | — |
| PSS010241 | — | — | 2,264 individuals, 45.0 % Male samples |
Mean = 58.0 years Sd = 7.1 years |
European | Ashkenazi | UKB | — |
| PSS000169 | — | — | 78,320 individuals, 46.0 % Male samples |
Mean = 57.26 years Range = [38.87, 70.99] years |
European | — | UKB | — |
| PSS011113 | — | — | 1,433 individuals | — | South Asian | — | UKB | — |
| PSS009009 | — | — | 3,711 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS006956 | — | — | 6,139 individuals | — | African unspecified | — | UKB | — |
| PSS006957 | — | — | 1,655 individuals | — | East Asian | — | UKB | — |
| PSS006958 | — | — | 24,175 individuals | — | European | non-white British ancestry | UKB | — |
| PSS006959 | — | — | 7,520 individuals | — | South Asian | — | UKB | — |
| PSS006960 | — | — | 65,636 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS008118 | — | — | 1,762 individuals | — | East Asian | China (East Asia) | UKB | — |