Trait: cystatin C measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004617
Description is a quantification of serum cystatin C C (formerly gamma trace, post-gamma-globulin or neuroendocrine basic polypeptide),[1] a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function and kidney disease.
Trait category
Other measurement
Mapped term NCIt:C92290

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS000680
(snpnet.Cystatin_C)
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Cystatin C [mg/L] cystatin C measurement 24,487
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000680/ScoringFiles/PGS000680.txt.gz - Check Terms/Licenses
PGS001947
(portability-PLR_log_cystatinC)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 84,459
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001947/ScoringFiles/PGS001947.txt.gz
PGS002165
(portability-ldpred2_log_cystatinC)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 781,302
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002165/ScoringFiles/PGS002165.txt.gz
PGS003279
(ExPRSweb_CysC_30720-irnt_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 879,560
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003279/ScoringFiles/PGS003279.txt.gz
PGS003280
(ExPRSweb_CysC_30720-irnt_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 346
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003280/ScoringFiles/PGS003280.txt.gz
PGS003281
(ExPRSweb_CysC_30720-irnt_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 415
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003281/ScoringFiles/PGS003281.txt.gz
PGS003282
(ExPRSweb_CysC_30720-irnt_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 7,451,904
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003282/ScoringFiles/PGS003282.txt.gz
PGS003283
(ExPRSweb_CysC_30720-irnt_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 1,113,831
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003283/ScoringFiles/PGS003283.txt.gz
PGS003284
(ExPRSweb_CysC_30720-raw_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 735,756
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003284/ScoringFiles/PGS003284.txt.gz
PGS003285
(ExPRSweb_CysC_30720-raw_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 931
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003285/ScoringFiles/PGS003285.txt.gz
PGS003286
(ExPRSweb_CysC_30720-raw_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 1,057
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003286/ScoringFiles/PGS003286.txt.gz
PGS003287
(ExPRSweb_CysC_30720-raw_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 7,451,726
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003287/ScoringFiles/PGS003287.txt.gz
PGS003288
(ExPRSweb_CysC_30720-raw_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Cystatin C cystatin C measurement 1,113,831
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003288/ScoringFiles/PGS003288.txt.gz
PGS003289
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
162,595
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003289/ScoringFiles/PGS003289.txt.gz
PGS003290
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
48
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003290/ScoringFiles/PGS003290.txt.gz
PGS003291
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
49
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003291/ScoringFiles/PGS003291.txt.gz
PGS003292
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
88,980
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003292/ScoringFiles/PGS003292.txt.gz
PGS003293
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
1,114,109
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003293/ScoringFiles/PGS003293.txt.gz
PGS003294
(ExPRSweb_CysC_eGFRcys-overall-EA_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
1,954
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003294/ScoringFiles/PGS003294.txt.gz
PGS003295
(ExPRSweb_CysC_eGFRcys-overall-EA_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
42
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003295/ScoringFiles/PGS003295.txt.gz
PGS003296
(ExPRSweb_CysC_eGFRcys-overall-EA_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
87
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003296/ScoringFiles/PGS003296.txt.gz
PGS003297
(ExPRSweb_CysC_eGFRcys-overall-EA_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
7,372
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003297/ScoringFiles/PGS003297.txt.gz
PGS003298
(ExPRSweb_CysC_eGFRcys-overall-EA_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
16,681
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003298/ScoringFiles/PGS003298.txt.gz
PGS003299
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
62,133
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003299/ScoringFiles/PGS003299.txt.gz
PGS003300
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
203
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003300/ScoringFiles/PGS003300.txt.gz
PGS003301
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
204
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003301/ScoringFiles/PGS003301.txt.gz
PGS003302
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
695,827
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003302/ScoringFiles/PGS003302.txt.gz
PGS003303
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
933,013
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003303/ScoringFiles/PGS003303.txt.gz
PGS003304
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_LASSOSUM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
174,315
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003304/ScoringFiles/PGS003304.txt.gz
PGS003305
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PT_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003305/ScoringFiles/PGS003305.txt.gz
PGS003306
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PLINK_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003306/ScoringFiles/PGS003306.txt.gz
PGS003307
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_DBSLMM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
11,672
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003307/ScoringFiles/PGS003307.txt.gz
PGS003308
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
1,114,999
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003308/ScoringFiles/PGS003308.txt.gz
PGS003309
(ExPRSweb_CysC_eGFRcys-overall-EA_LASSOSUM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
1,954
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003309/ScoringFiles/PGS003309.txt.gz
PGS003310
(ExPRSweb_CysC_eGFRcys-overall-EA_PT_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
6
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003310/ScoringFiles/PGS003310.txt.gz
PGS003311
(ExPRSweb_CysC_eGFRcys-overall-EA_PLINK_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003311/ScoringFiles/PGS003311.txt.gz
PGS003312
(ExPRSweb_CysC_eGFRcys-overall-EA_DBSLMM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
6,375
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003312/ScoringFiles/PGS003312.txt.gz
PGS003313
(ExPRSweb_CysC_eGFRcys-overall-EA_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
16,685
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003313/ScoringFiles/PGS003313.txt.gz
PGS003314
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_LASSOSUM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
62,626
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003314/ScoringFiles/PGS003314.txt.gz
PGS003315
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PT_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
2
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003315/ScoringFiles/PGS003315.txt.gz
PGS003316
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PLINK_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
2
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003316/ScoringFiles/PGS003316.txt.gz
PGS003317
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_DBSLMM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
594,334
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003317/ScoringFiles/PGS003317.txt.gz
PGS003318
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
933,341
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003318/ScoringFiles/PGS003318.txt.gz
PGS003528
(cont-decay-log_cystatinC)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Cystatin C cystatin C measurement 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003528/ScoringFiles/PGS003528.txt.gz
PGS003589
(UKB_cycproduction_EUR)
PGP000463 |
Kleeman SO et al. Cell Genom (2023)
Cystatin C production cystatin C measurement 1,031,527
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003589/ScoringFiles/PGS003589.txt.gz
PGS003590
(UKB_cycproduction_EUR_exome)
PGP000463 |
Kleeman SO et al. Cell Genom (2023)
Cystatin C production cystatin C measurement 352,549
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003590/ScoringFiles/PGS003590.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM001408 PGS000680
(snpnet.Cystatin_C)
PSS000677|
African Ancestry|
6,015 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Cystatin C [mg/L] : 0.17697
Spearman's ρ: 0.196
Age, sex, PCs(1-40)
PPM001443 PGS000680
(snpnet.Cystatin_C)
PSS000678|
East Asian Ancestry|
1,082 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Cystatin C [mg/L] : 0.28853
Spearman's ρ: 0.274
Age, sex, PCs(1-40)
PPM001478 PGS000680
(snpnet.Cystatin_C)
PSS000679|
European Ancestry|
23,580 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Cystatin C [mg/L] Spearman's ρ: 0.391
: 0.30498
Age, sex, PCs(1-40)
PPM001513 PGS000680
(snpnet.Cystatin_C)
PSS000680|
South Asian Ancestry|
7,338 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Cystatin C [mg/L] : 0.26742
Spearman's ρ: 0.323
Age, sex, PCs(1-40)
PPM001548 PGS000680
(snpnet.Cystatin_C)
PSS000681|
European Ancestry|
63,762 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Cystatin C [mg/L] : 0.29509
Spearman's ρ: 0.405
Age, sex, PCs(1-40)
PPM001591 PGS000680
(snpnet.Cystatin_C)
PSS000802|
European Ancestry|
2,116 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Cystatin C [mg/L] Spearman's ρ: 0.255 Age, sex
PPM007325 PGS000680
(snpnet.Cystatin_C)
PSS007141|
African Ancestry|
6,098 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Cystatin C : 0.11726 [0.10257, 0.13195]
Incremental R2 (full-covars): 0.00628
PGS R2 (no covariates): 0.01457 [0.00879, 0.02036]
age, sex, UKB array type, Genotype PCs
PPM007326 PGS000680
(snpnet.Cystatin_C)
PSS007142|
East Asian Ancestry|
1,617 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Cystatin C : 0.22897 [0.194, 0.26393]
Incremental R2 (full-covars): 0.02178
PGS R2 (no covariates): 0.03277 [0.01618, 0.04936]
age, sex, UKB array type, Genotype PCs
PPM007327 PGS000680
(snpnet.Cystatin_C)
PSS007143|
European Ancestry|
23,779 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Cystatin C : 0.20012 [0.19124, 0.20901]
Incremental R2 (full-covars): 0.07378
PGS R2 (no covariates): 0.07907 [0.07263, 0.0855]
age, sex, UKB array type, Genotype PCs
PPM007328 PGS000680
(snpnet.Cystatin_C)
PSS007144|
South Asian Ancestry|
7,426 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Cystatin C : 0.16627 [0.15122, 0.18132]
Incremental R2 (full-covars): 0.03349
PGS R2 (no covariates): 0.03448 [0.02654, 0.04242]
age, sex, UKB array type, Genotype PCs
PPM007329 PGS000680
(snpnet.Cystatin_C)
PSS007145|
European Ancestry|
64,468 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.
Reported Trait: Cystatin C : 0.21975 [0.21423, 0.22528]
Incremental R2 (full-covars): 0.09316
PGS R2 (no covariates): 0.09133 [0.08718, 0.09548]
age, sex, UKB array type, Genotype PCs
PPM010455 PGS001947
(portability-PLR_log_cystatinC)
PSS008321|
South Asian Ancestry|
6,001 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.3057 [0.2826, 0.3285] sex, age, birth date, deprivation index, 16 PCs
PPM010451 PGS001947
(portability-PLR_log_cystatinC)
PSS009441|
European Ancestry|
18,996 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.418 [0.4062, 0.4297] sex, age, birth date, deprivation index, 16 PCs
PPM010452 PGS001947
(portability-PLR_log_cystatinC)
PSS009215|
European Ancestry|
3,953 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.4317 [0.4059, 0.4568] sex, age, birth date, deprivation index, 16 PCs
PPM010454 PGS001947
(portability-PLR_log_cystatinC)
PSS008543|
Greater Middle Eastern Ancestry|
1,126 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.3385 [0.2852, 0.3897] sex, age, birth date, deprivation index, 16 PCs
PPM010457 PGS001947
(portability-PLR_log_cystatinC)
PSS007885|
African Ancestry|
2,342 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.1917 [0.1522, 0.2306] sex, age, birth date, deprivation index, 16 PCs
PPM010458 PGS001947
(portability-PLR_log_cystatinC)
PSS008989|
African Ancestry|
3,658 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.1856 [0.1541, 0.2168] sex, age, birth date, deprivation index, 16 PCs
PPM010453 PGS001947
(portability-PLR_log_cystatinC)
PSS008769|
European Ancestry|
6,319 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.3864 [0.3652, 0.4072] sex, age, birth date, deprivation index, 16 PCs
PPM010456 PGS001947
(portability-PLR_log_cystatinC)
PSS008098|
East Asian Ancestry|
1,718 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.2689 [0.2242, 0.3125] sex, age, birth date, deprivation index, 16 PCs
PPM012167 PGS002165
(portability-ldpred2_log_cystatinC)
PSS009441|
European Ancestry|
18,996 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.4072 [0.3953, 0.419] sex, age, birth date, deprivation index, 16 PCs
PPM012168 PGS002165
(portability-ldpred2_log_cystatinC)
PSS009215|
European Ancestry|
3,953 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.4276 [0.4017, 0.4528] sex, age, birth date, deprivation index, 16 PCs
PPM012169 PGS002165
(portability-ldpred2_log_cystatinC)
PSS008769|
European Ancestry|
6,319 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.371 [0.3495, 0.3921] sex, age, birth date, deprivation index, 16 PCs
PPM012170 PGS002165
(portability-ldpred2_log_cystatinC)
PSS008543|
Greater Middle Eastern Ancestry|
1,126 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.3446 [0.2916, 0.3956] sex, age, birth date, deprivation index, 16 PCs
PPM012171 PGS002165
(portability-ldpred2_log_cystatinC)
PSS008321|
South Asian Ancestry|
6,001 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.3009 [0.2777, 0.3238] sex, age, birth date, deprivation index, 16 PCs
PPM012173 PGS002165
(portability-ldpred2_log_cystatinC)
PSS007885|
African Ancestry|
2,342 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.181 [0.1414, 0.2201] sex, age, birth date, deprivation index, 16 PCs
PPM012174 PGS002165
(portability-ldpred2_log_cystatinC)
PSS008989|
African Ancestry|
3,658 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.1653 [0.1335, 0.1967] sex, age, birth date, deprivation index, 16 PCs
PPM012172 PGS002165
(portability-ldpred2_log_cystatinC)
PSS008098|
East Asian Ancestry|
1,718 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C Partial Correlation (partial-r): 0.2565 [0.2115, 0.3004] sex, age, birth date, deprivation index, 16 PCs
PPM015728 PGS003279
(ExPRSweb_CysC_30720-irnt_LASSOSUM_MGI_20211120)
PSS010000|
Ancestry Not Reported|
213 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0115 (0.0535) : 0.00174 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015731 PGS003280
(ExPRSweb_CysC_30720-irnt_PT_MGI_20211120)
PSS010000|
Ancestry Not Reported|
213 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0229 (0.0513) : 4e-05 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015729 PGS003281
(ExPRSweb_CysC_30720-irnt_PLINK_MGI_20211120)
PSS010000|
Ancestry Not Reported|
213 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0217 (0.0481) : 7.56e-07 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015727 PGS003282
(ExPRSweb_CysC_30720-irnt_DBSLMM_MGI_20211120)
PSS010000|
Ancestry Not Reported|
213 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0119 (0.0509) : 0.00026 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015730 PGS003283
(ExPRSweb_CysC_30720-irnt_PRSCS_MGI_20211120)
PSS010000|
Ancestry Not Reported|
213 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.00096 (0.0523) : 0.00308 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015733 PGS003284
(ExPRSweb_CysC_30720-raw_LASSOSUM_MGI_20211120)
PSS010000|
Ancestry Not Reported|
213 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0222 (0.0552) : 0.00215 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015736 PGS003285
(ExPRSweb_CysC_30720-raw_PT_MGI_20211120)
PSS010000|
Ancestry Not Reported|
213 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0277 (0.049) : 6.50e-07 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015734 PGS003286
(ExPRSweb_CysC_30720-raw_PLINK_MGI_20211120)
PSS010000|
Ancestry Not Reported|
213 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0177 (0.0484) : 0.00011 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015732 PGS003287
(ExPRSweb_CysC_30720-raw_DBSLMM_MGI_20211120)
PSS010000|
Ancestry Not Reported|
213 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0205 (0.051) : 4e-05 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015735 PGS003288
(ExPRSweb_CysC_30720-raw_PRSCS_MGI_20211120)
PSS010000|
Ancestry Not Reported|
213 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: 0.0125 (0.0558) : 0.00245 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015739 PGS003289
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_LASSOSUM_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: -0.0524 (0.0525) : 0.00038 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015745 PGS003290
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PT_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: -0.0298 (0.0525) : 2e-05 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015741 PGS003291
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PLINK_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: -0.0339 (0.0521) : 0.0001 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015737 PGS003292
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_DBSLMM_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: 0.0339 (0.0485) : 0.00258 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015743 PGS003293
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PRSCS_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: 0.00954 (0.0537) : 0.0131 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015749 PGS003294
(ExPRSweb_CysC_eGFRcys-overall-EA_LASSOSUM_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: -0.0131 (0.0552) : 0.00398 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015755 PGS003295
(ExPRSweb_CysC_eGFRcys-overall-EA_PT_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: 0.0475 (0.0562) : 0.00743 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015751 PGS003296
(ExPRSweb_CysC_eGFRcys-overall-EA_PLINK_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: -0.0261 (0.0529) : 3e-05 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015747 PGS003297
(ExPRSweb_CysC_eGFRcys-overall-EA_DBSLMM_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: -0.0371 (0.0545) : 0.00926 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015753 PGS003298
(ExPRSweb_CysC_eGFRcys-overall-EA_PRSCS_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: 0.0457 (0.049) : 0.0103 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015759 PGS003299
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_LASSOSUM_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: -0.021 (0.0515) : 0.015 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015765 PGS003300
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PT_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: 0.0484 (0.0519) : 0.00015 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015761 PGS003301
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PLINK_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: 0.0486 (0.0519) : 7e-05 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015757 PGS003302
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_DBSLMM_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: 0.0163 (0.0472) : 0.00069 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015763 PGS003303
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PRSCS_MGI_20211120)
PSS010020|
European Ancestry|
19,504 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: eGFR β: -0.0446 (0.0567) : 0.0349 SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015740 PGS003304
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_LASSOSUM_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: 0.0328 (0.000358) : 0.0356 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015746 PGS003305
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PT_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: 0.0314 (0.000359) : 0.0326 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015742 PGS003306
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PLINK_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: 0.0314 (0.000359) : 0.0326 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015738 PGS003307
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_DBSLMM_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.00171 (0.000365) : 0.0001 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015744 PGS003308
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PRSCS_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: 0.0275 (0.00036) : 0.0251 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015750 PGS003309
(ExPRSweb_CysC_eGFRcys-overall-EA_LASSOSUM_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0311 (0.000352) : 0.0335 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015756 PGS003310
(ExPRSweb_CysC_eGFRcys-overall-EA_PT_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0294 (0.000353) : 0.03 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015752 PGS003311
(ExPRSweb_CysC_eGFRcys-overall-EA_PLINK_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0297 (0.000353) : 0.0304 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015748 PGS003312
(ExPRSweb_CysC_eGFRcys-overall-EA_DBSLMM_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0285 (0.000353) : 0.0282 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015754 PGS003313
(ExPRSweb_CysC_eGFRcys-overall-EA_PRSCS_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0101 (0.000359) : 0.00374 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015760 PGS003314
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_LASSOSUM_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0329 (0.000351) : 0.0375 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015766 PGS003315
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PT_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0312 (0.000352) : 0.0336 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015762 PGS003316
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PLINK_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0312 (0.000352) : 0.0336 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015758 PGS003317
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_DBSLMM_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0155 (0.000358) : 0.0084 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015764 PGS003318
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PRSCS_UKB_20211120)
PSS010026|
European Ancestry|
390,221 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Cystatin C β: -0.0272 (0.000354) : 0.0255 Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM017456 PGS003528
(cont-decay-log_cystatinC)
PSS010891|
European Ancestry|
19,120 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Cystatin C partial-R2: 0.16 sex, age, deprivation index, PC1-16
PPM017540 PGS003528
(cont-decay-log_cystatinC)
PSS010807|
European Ancestry|
3,942 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Cystatin C partial-R2: 0.18 sex, age, deprivation index, PC1-16
PPM017624 PGS003528
(cont-decay-log_cystatinC)
PSS010639|
European Ancestry|
6,167 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Cystatin C partial-R2: 0.14 sex, age, deprivation index, PC1-16
PPM017708 PGS003528
(cont-decay-log_cystatinC)
PSS010555|
Greater Middle Eastern Ancestry|
1,097 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Cystatin C partial-R2: 0.12 sex, age, deprivation index, PC1-16
PPM017792 PGS003528
(cont-decay-log_cystatinC)
PSS010219|
European Ancestry|
2,236 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Cystatin C partial-R2: 0.12 sex, age, deprivation index, PC1-16
PPM017876 PGS003528
(cont-decay-log_cystatinC)
PSS010471|
South Asian Ancestry|
5,948 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Cystatin C partial-R2: 0.09 sex, age, deprivation index, PC1-16
PPM017960 PGS003528
(cont-decay-log_cystatinC)
PSS010387|
East Asian Ancestry|
1,707 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Cystatin C partial-R2: 0.06 sex, age, deprivation index, PC1-16
PPM018044 PGS003528
(cont-decay-log_cystatinC)
PSS010303|
African Ancestry|
2,330 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Cystatin C partial-R2: 0.03 sex, age, deprivation index, PC1-16
PPM018128 PGS003528
(cont-decay-log_cystatinC)
PSS010723|
African Ancestry|
3,629 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Cystatin C partial-R2: 0.03 sex, age, deprivation index, PC1-16
PPM018283 PGS003589
(UKB_cycproduction_EUR)
PSS010957|
European Ancestry|
50,000 individuals
PGP000463 |
Kleeman SO et al. Cell Genom (2023)
Reported Trait: Cystatin C production : 0.08 Age, sex, PC1-4, recruitment center, genotyping array
PPM018284 PGS003590
(UKB_cycproduction_EUR_exome)
PSS010957|
European Ancestry|
50,000 individuals
PGP000463 |
Kleeman SO et al. Cell Genom (2023)
Reported Trait: Cystatin C production : 0.04 Age, sex, PC1-4, recruitment center, genotyping array

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000679 23,580 individuals European Non-British White UKB
PSS000680 7,338 individuals South Asian UKB
PSS000681 63,762 individuals European
(British)
UKB
PSS007885 2,342 individuals African American or Afro-Caribbean Carribean UKB
PSS010807 3,942 individuals,
38.0 % Male samples
Mean = 54.4 years
Sd = 7.5 years
European Polish UKB
PSS008543 1,126 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009441 18,996 individuals European UK (+ Ireland) UKB
PSS010555 1,097 individuals,
60.0 % Male samples
Mean = 51.9 years
Sd = 8.0 years
Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB
PSS010303 2,330 individuals,
37.0 % Male samples
Mean = 52.5 years
Sd = 8.1 years
African American or Afro-Caribbean Caribbean UKB
PSS007141 6,098 individuals African unspecified UKB
PSS007142 1,617 individuals East Asian UKB
PSS007143 23,779 individuals European non-white British ancestry UKB
PSS007144 7,426 individuals South Asian UKB
PSS007145 64,468 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS010000 213 individuals Not reported MGI
PSS009215 3,953 individuals European Poland (NE Europe) UKB
PSS008321 6,001 individuals South Asian India (South Asia) UKB
PSS010020 Estimated GFR, Non-Black (LOINC: 48642-3); Quantitative 19,504 individuals European MGI
PSS010723 3,629 individuals,
46.0 % Male samples
Mean = 51.9 years
Sd = 8.1 years
African unspecified Nigerian UKB
PSS010471 5,948 individuals,
54.0 % Male samples
Mean = 53.3 years
Sd = 8.4 years
South Asian Indian UKB
PSS010957 50,000 individuals European UKB
PSS010026 Field ID: 30720; Quantitative 195,103 individuals European UKB
PSS010026 Field ID: 30720; Quantitative 195,118 individuals European UKB
PSS010219 2,236 individuals,
45.0 % Male samples
Mean = 58.1 years
Sd = 7.1 years
European Ashkenazi UKB
PSS008989 3,658 individuals African unspecified Nigeria (West Africa) UKB
PSS008098 1,718 individuals East Asian China (East Asia) UKB
PSS010891 19,120 individuals,
46.0 % Male samples
Mean = 56.9 years
Sd = 7.9 years
European white British UKB
PSS010639 6,167 individuals,
45.0 % Male samples
Mean = 54.5 years
Sd = 8.4 years
European Italian UKB
PSS010387 1,707 individuals,
33.0 % Male samples
Mean = 52.4 years
Sd = 7.8 years
East Asian Chinese UKB
PSS000802 2,116 individuals European Participants self-identifying as white MESA
PSS008769 6,319 individuals European Italy (South Europe) UKB
PSS000677 6,015 individuals African unspecified UKB
PSS000678 1,082 individuals East Asian UKB