Trait: insulin like growth factor measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004628
Description Is a quantification of any of the insulin like growth factors
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002295
(GRS413_IGF-1)
 PGP000325 |
Tsai CW et al. American Journal of Cancer Research (2022)
 Insulin growth-like factor-1 level insulin like growth factor measurement 413
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002295/ScoringFiles/PGS002295.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM013023 PGS002295
(GRS413_IGF-1)
 PSS009653|
European Ancestry|
1,010 individuals
 PGP000325 |
Tsai CW et al. American Journal of Cancer Research (2022)
 Reported Trait: Recurrence in renal cell carcinoma HR: 0.63 [0.42, 0.93] — Hazard Ratio (HR, above vs. below median): 0.63 [0.42, 0.93]
Odds Ratio (OR, above vs. below 75th percentile GRS): 0.73 [0.55, 0.96]		 Age, gender, smoking status, BMI, histology, stage, grade, and treatment —
PPM013024 PGS002295
(GRS413_IGF-1)
 PSS009653|
European Ancestry|
1,010 individuals
 PGP000325 |
Tsai CW et al. American Journal of Cancer Research (2022)
 Reported Trait: Survival in renal cell carcinoma HR: 0.65 [0.44, 0.95] — Hazard Ratio (HR, above vs. below median): 0.65 [0.44, 0.95]
Odds Ratio (OR, above vs. below 75th percentile GRS): 0.66 [0.5, 0.87]		 Age, gender, smoking status, BMI, histology, stage, grade, and treatment —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009653 — — 1,010 individuals — European — NR —