Experimental Factor Ontology (EFO) Information | |
Identifier | EFO_0004723 |
Description | Calcification of the coronary artery, used as a measure of coronary atherosclerosis, a risk factor for myocardial infarction. | Trait category |
Cardiovascular disease
|
Mapped term | MedDRA:10064747 |
Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
---|---|---|---|---|---|---|
PGS005096 (CAC_GRS) |
PGP000689 | Mishra PP et al. Am J Prev Cardiol (2024) |
Coronary artery calcification | coronary artery calcification | 11 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005096/ScoringFiles/PGS005096.txt.gz |
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|---|
PPM022192 | PGS005096 (CAC_GRS) |
PSS011838| European Ancestry| 2,742 individuals |
PGP000689 | Mishra PP et al. Am J Prev Cardiol (2024) |
Reported Trait: Coronary artery disease | OR: 1.41 [1.28, 1.55] | — | — | Age, sex, systolic blood pressure, total cholesterol, HDL cholesterol, smoking status, hypertension medication, 5 PCs | — |
PPM022193 | PGS005096 (CAC_GRS) |
PSS011839| European Ancestry| 622 individuals |
PGP000689 | Mishra PP et al. Am J Prev Cardiol (2024) |
Reported Trait: Coronary artery disease | OR: 4.2 [1.74, 10.52] | — | — | Age, sex, BMI, smoking status, hypertension medication, 5 PCs | — |
PPM022194 | PGS005096 (CAC_GRS) |
PSS011840| European Ancestry| 133 individuals |
PGP000689 | Mishra PP et al. Am J Prev Cardiol (2024) |
Reported Trait: Coronary artery disease | OR: 1.79 [1.05, 3.21] | — | — | Age, sex, systolic blood pressure, total cholesterol, HDL cholesterol, smoking status, hypertension medication, 5 PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS011839 | — | — | [ ,
75.0 % Male samples |
— | European | — | TSDS | — |
PSS011840 | — | — | [ ,
71.0 % Male samples |
— | European | — | TVS | — |
PSS011838 | — | — | [ ,
71.0 % Male samples |
— | European | — | LURIC | — |