Trait: hippocampal volume

Experimental Factor Ontology (EFO) Information
Identifier EFO_0005035
Description Measurement of the volume of the hippocampus
Trait category
Other measurement
Child trait(s) 4 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "hippocampal volume" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001630
(GBE_INI25019)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Volume of hippocampus (L) neuroimaging measurement,
hippocampal volume		 442
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001630/ScoringFiles/PGS001630.txt.gz
PGS003603
(L_HATA_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampus-amygdala transition area volume hippocampal amigdala transition area volume 83,449
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003603/ScoringFiles/PGS003603.txt.gz
PGS003604
(R_HATA_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampus-amygdala transition area volume hippocampal amigdala transition area volume 1,363
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003604/ScoringFiles/PGS003604.txt.gz
PGS003605
(L_HATA_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampus-amygdala transition area volume hippocampal amigdala transition area volume 30,268
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003605/ScoringFiles/PGS003605.txt.gz
PGS003606
(R_HATA_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampus-amygdala transition area volume hippocampal amigdala transition area volume 61,932
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003606/ScoringFiles/PGS003606.txt.gz
PGS003607
(L_HATA_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampus-amygdala transition area volume hippocampal amigdala transition area volume 67,474
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003607/ScoringFiles/PGS003607.txt.gz
PGS003608
(R_HATA_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampus-amygdala transition area volume hippocampal amigdala transition area volume 138,503
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003608/ScoringFiles/PGS003608.txt.gz
PGS003609
(L_CA1_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA1 body volume hippocampal CA1 volume 40,494
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003609/ScoringFiles/PGS003609.txt.gz
PGS003610
(L_CA1_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA1 head volume hippocampal CA1 volume 792
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003610/ScoringFiles/PGS003610.txt.gz
PGS003611
(R_CA1_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA1 body volume hippocampal CA1 volume 7,104
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003611/ScoringFiles/PGS003611.txt.gz
PGS003612
(R_CA1_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA1 head volume hippocampal CA1 volume 6,252
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003612/ScoringFiles/PGS003612.txt.gz
PGS003613
(L_CA1_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA1 body volume hippocampal CA1 volume 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003613/ScoringFiles/PGS003613.txt.gz
PGS003614
(L_CA1_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA1 head volume hippocampal CA1 volume 8,634
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003614/ScoringFiles/PGS003614.txt.gz
PGS003615
(R_CA1_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA1 body volume hippocampal CA1 volume 123,648
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003615/ScoringFiles/PGS003615.txt.gz
PGS003616
(R_CA1_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA1 head volume hippocampal CA1 volume 19,937
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003616/ScoringFiles/PGS003616.txt.gz
PGS003617
(L_CA1_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA1 body volume hippocampal CA1 volume 205
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003617/ScoringFiles/PGS003617.txt.gz
PGS003618
(L_CA1_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA1 head volume hippocampal CA1 volume 57
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003618/ScoringFiles/PGS003618.txt.gz
PGS003619
(R_CA1_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA1 body volume hippocampal CA1 volume 189
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003619/ScoringFiles/PGS003619.txt.gz
PGS003620
(R_CA1_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA1 head volume hippocampal CA1 volume 19,628
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003620/ScoringFiles/PGS003620.txt.gz
PGS003621
(L_CA3_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA3 body volume hippocampal CA3 volume 20,796
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003621/ScoringFiles/PGS003621.txt.gz
PGS003622
(L_CA3_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA3 head volume hippocampal CA3 volume 14,099
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003622/ScoringFiles/PGS003622.txt.gz
PGS003623
(R_CA3_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA3 body volume hippocampal CA3 volume 9,398
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003623/ScoringFiles/PGS003623.txt.gz
PGS003624
(R_CA3_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA3 head volume hippocampal CA3 volume 594
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003624/ScoringFiles/PGS003624.txt.gz
PGS003625
(L_CA3_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA3 body volume hippocampal CA3 volume 1,034
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003625/ScoringFiles/PGS003625.txt.gz
PGS003626
(L_CA3_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA3 head volume hippocampal CA3 volume 14,199
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003626/ScoringFiles/PGS003626.txt.gz
PGS003627
(R_CA3_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA3 body volume hippocampal CA3 volume 3,205
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003627/ScoringFiles/PGS003627.txt.gz
PGS003628
(R_CA3_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA3 head volume hippocampal CA3 volume 19,760
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003628/ScoringFiles/PGS003628.txt.gz
PGS003629
(L_CA3_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA3 body volume hippocampal CA3 volume 24,206
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003629/ScoringFiles/PGS003629.txt.gz
PGS003630
(L_CA3_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA3 head volume hippocampal CA3 volume 2,341
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003630/ScoringFiles/PGS003630.txt.gz
PGS003631
(R_CA3_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA3 body volume hippocampal CA3 volume 6,731
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003631/ScoringFiles/PGS003631.txt.gz
PGS003632
(R_CA3_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA3 head volume hippocampal CA3 volume 38,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003632/ScoringFiles/PGS003632.txt.gz
PGS003633
(L_CA4_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA4 head volume hippocampal CA4 volume 22,605
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003633/ScoringFiles/PGS003633.txt.gz
PGS003634
(L_CA4_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA4 body volume hippocampal CA4 volume 375
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003634/ScoringFiles/PGS003634.txt.gz
PGS003635
(R_CA4_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA4 head volume hippocampal CA4 volume 12,506
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003635/ScoringFiles/PGS003635.txt.gz
PGS003636
(R_CA4_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA4 body volume hippocampal CA4 volume 3,322
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003636/ScoringFiles/PGS003636.txt.gz
PGS003637
(L_CA4_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA4 head volume hippocampal CA4 volume 84,284
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003637/ScoringFiles/PGS003637.txt.gz
PGS003638
(L_CA4_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA4 body volume hippocampal CA4 volume 894
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003638/ScoringFiles/PGS003638.txt.gz
PGS003639
(R_CA4_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA4 head volume hippocampal CA4 volume 3,200
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003639/ScoringFiles/PGS003639.txt.gz
PGS003640
(R_CA4_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA4 body volume hippocampal CA4 volume 497
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003640/ScoringFiles/PGS003640.txt.gz
PGS003641
(L_CA4_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA4 head volume hippocampal CA4 volume 48
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003641/ScoringFiles/PGS003641.txt.gz
PGS003642
(L_CA4_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA4 body volume hippocampal CA4 volume 3,644
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003642/ScoringFiles/PGS003642.txt.gz
PGS003643
(R_CA4_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA4 head volume hippocampal CA4 volume 73,791
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003643/ScoringFiles/PGS003643.txt.gz
PGS003644
(R_CA4_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA4 body volume hippocampal CA4 volume 10,113
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003644/ScoringFiles/PGS003644.txt.gz
PGS003657
(L_hippocampus_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampus volume hippocampal volume 753
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003657/ScoringFiles/PGS003657.txt.gz
PGS003658
(R_hippocampus_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampus volume hippocampal volume 1,926
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003658/ScoringFiles/PGS003658.txt.gz
PGS003659
(L_hippocampal_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal body volume hippocampal volume 462
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003659/ScoringFiles/PGS003659.txt.gz
PGS003660
(L_hippocampal_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal head volume hippocampal volume 32,033
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003660/ScoringFiles/PGS003660.txt.gz
PGS003661
(R_hippocampal_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampal body volume hippocampal volume 279
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003661/ScoringFiles/PGS003661.txt.gz
PGS003662
(R_hippocampal_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampal head volume hippocampal volume 8,431
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003662/ScoringFiles/PGS003662.txt.gz
PGS003663
(L_hippocampus_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampus volume hippocampal volume 197
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003663/ScoringFiles/PGS003663.txt.gz
PGS003664
(R_hippocampus_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampus volume hippocampal volume 2,804
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003664/ScoringFiles/PGS003664.txt.gz
PGS003665
(L_hippocampal_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal body volume hippocampal volume 164
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003665/ScoringFiles/PGS003665.txt.gz
PGS003666
(L_hippocampal_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal head volume hippocampal volume 57,883
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003666/ScoringFiles/PGS003666.txt.gz
PGS003667
(R_hippocampal_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampal body volume hippocampal volume 2,784
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003667/ScoringFiles/PGS003667.txt.gz
PGS003668
(R_hippocampal_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampal head volume hippocampal volume 2,502
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003668/ScoringFiles/PGS003668.txt.gz
PGS003669
(L_hippocampus_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampus volume hippocampal volume 37,136
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003669/ScoringFiles/PGS003669.txt.gz
PGS003670
(R_hippocampus_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampus volume hippocampal volume 100,023
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003670/ScoringFiles/PGS003670.txt.gz
PGS003671
(L_hippocampal_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal body volume hippocampal volume 74,820
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003671/ScoringFiles/PGS003671.txt.gz
PGS003672
(L_hippocampal_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal head volume hippocampal volume 201
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003672/ScoringFiles/PGS003672.txt.gz
PGS003673
(R_hippocampal_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampal body volume hippocampal volume 37,159
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003673/ScoringFiles/PGS003673.txt.gz
PGS003674
(R_hippocampal_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampal head volume hippocampal volume 79,660
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003674/ScoringFiles/PGS003674.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM005440 PGS001630
(GBE_INI25019)
 PSS005276|
African Ancestry|
200 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Vol. of hippocampus (L) — — R²: 0.13049 [0.11522, 0.14576]
Incremental R2 (full-covars): -0.00825
PGS R2 (no covariates): 0.0 [-0.00005, 0.00005]		 age, sex, UKB array type, Genotype PCs —
PPM005441 PGS001630
(GBE_INI25019)
 PSS005277|
East Asian Ancestry|
113 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Vol. of hippocampus (L) — — R²: 0.26457 [0.22872, 0.30042]
Incremental R2 (full-covars): 0.01199
PGS R2 (no covariates): 0.0194 [0.00646, 0.03235]		 age, sex, UKB array type, Genotype PCs —
PPM005442 PGS001630
(GBE_INI25019)
 PSS005278|
European Ancestry|
1,739 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Vol. of hippocampus (L) — — R²: 0.14648 [0.13837, 0.1546]
Incremental R2 (full-covars): 0.00716
PGS R2 (no covariates): 0.00755 [0.00541, 0.00969]		 age, sex, UKB array type, Genotype PCs —
PPM005443 PGS001630
(GBE_INI25019)
 PSS005279|
South Asian Ancestry|
328 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Vol. of hippocampus (L) — — R²: 0.2658 [0.24904, 0.28256]
Incremental R2 (full-covars): 0.00259
PGS R2 (no covariates): 0.00435 [0.00144, 0.00725]		 age, sex, UKB array type, Genotype PCs —
PPM005444 PGS001630
(GBE_INI25019)
 PSS005280|
European Ancestry|
5,443 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Vol. of hippocampus (L) — — R²: 0.11388 [0.10937, 0.11839]
Incremental R2 (full-covars): 0.00801
PGS R2 (no covariates): 0.00917 [0.00774, 0.0106]		 age, sex, UKB array type, Genotype PCs —
PPM018305 PGS003603
(L_HATA_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampus-amygdala transition area volume — — R²: 0.0036 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018326 PGS003604
(R_HATA_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampus-amygdala transition area volume — — R²: 0.00789 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018349 PGS003605
(L_HATA_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampus-amygdala transition area volume — — R²: 0.00582 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018370 PGS003606
(R_HATA_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampus-amygdala transition area volume — — R²: 0.00273 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018393 PGS003607
(L_HATA_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampus-amygdala transition area volume — — R²: 0.00383 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018414 PGS003608
(R_HATA_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampus-amygdala transition area volume — — R²: 0.00653 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018289 PGS003609
(L_CA1_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA1 body volume — — R²: 0.01292 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018293 PGS003610
(L_CA1_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA1 head volume — — R²: 0.01741 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018310 PGS003611
(R_CA1_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA1 body volume — — R²: 0.02285 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018314 PGS003612
(R_CA1_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA1 head volume — — R²: 0.01716 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018333 PGS003613
(L_CA1_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA1 body volume — — R²: 0.00563 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018337 PGS003614
(L_CA1_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA1 head volume — — R²: 0.00629 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018354 PGS003615
(R_CA1_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA1 body volume — — R²: 0.00771 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018358 PGS003616
(R_CA1_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA1 head volume — — R²: 0.01234 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018377 PGS003617
(L_CA1_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA1 body volume — — R²: 0.00468 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018381 PGS003618
(L_CA1_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA1 head volume — — R²: 0.00364 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018398 PGS003619
(R_CA1_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA1 body volume — — R²: 0.00624 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018402 PGS003620
(R_CA1_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA1 head volume — — R²: 0.00515 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018299 PGS003621
(L_CA3_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA3 body volume — — R²: 0.01029 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018304 PGS003622
(L_CA3_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA3 head volume — — R²: 0.01199 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018320 PGS003623
(R_CA3_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA3 body volume — — R²: 0.00959 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018325 PGS003624
(R_CA3_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA3 head volume — — R²: 0.00758 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018343 PGS003625
(L_CA3_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA3 body volume — — R²: 0.00528 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018348 PGS003626
(L_CA3_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA3 head volume — — R²: 0.00737 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018364 PGS003627
(R_CA3_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA3 body volume — — R²: 0.00824 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018369 PGS003628
(R_CA3_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA3 head volume — — R²: 0.0063 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018387 PGS003629
(L_CA3_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA3 body volume — — R²: 0.00577 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018392 PGS003630
(L_CA3_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA3 head volume — — R²: 0.00652 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018408 PGS003631
(R_CA3_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA3 body volume — — R²: 0.00404 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018413 PGS003632
(R_CA3_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA3 head volume — — R²: 0.00322 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018301 PGS003633
(L_CA4_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA4 head volume — — R²: 0.01738 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018302 PGS003634
(L_CA4_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA4 body volume — — R²: 0.01659 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018322 PGS003635
(R_CA4_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA4 head volume — — R²: 0.00944 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018323 PGS003636
(R_CA4_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA4 body volume — — R²: 0.01436 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018345 PGS003637
(L_CA4_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA4 head volume — — R²: 0.00534 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018346 PGS003638
(L_CA4_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA4 body volume — — R²: 0.00901 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018366 PGS003639
(R_CA4_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA4 head volume — — R²: 0.00383 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018367 PGS003640
(R_CA4_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA4 body volume — — R²: 0.0079 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018389 PGS003641
(L_CA4_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA4 head volume — — R²: 0.00336 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018390 PGS003642
(L_CA4_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left CA4 body volume — — R²: 0.01072 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018410 PGS003643
(R_CA4_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA4 head volume — — R²: 0.00344 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018411 PGS003644
(R_CA4_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right CA4 body volume — — R²: 0.01166 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018285 PGS003657
(L_hippocampus_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampus volume — — R²: 0.02795 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018286 PGS003658
(R_hippocampus_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampus volume — — R²: 0.02214 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018306 PGS003659
(L_hippocampal_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampal body volume — — R²: 0.02046 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018307 PGS003660
(L_hippocampal_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampal head volume — — R²: 0.01933 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018327 PGS003661
(R_hippocampal_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampal body volume — — R²: 0.02106 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018328 PGS003662
(R_hippocampal_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampal head volume — — R²: 0.01873 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018329 PGS003663
(L_hippocampus_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampus volume — — R²: 0.01226 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018330 PGS003664
(R_hippocampus_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampus volume — — R²: 0.01279 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018350 PGS003665
(L_hippocampal_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampal body volume — — R²: 0.0115 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018351 PGS003666
(L_hippocampal_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampal head volume — — R²: 0.0106 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018371 PGS003667
(R_hippocampal_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampal body volume — — R²: 0.01402 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018372 PGS003668
(R_hippocampal_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampal head volume — — R²: 0.01353 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018373 PGS003669
(L_hippocampus_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampus volume — — R²: 0.00569 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018374 PGS003670
(R_hippocampus_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampus volume — — R²: 0.00659 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018394 PGS003671
(L_hippocampal_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampal body volume — — R²: 0.00439 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018395 PGS003672
(L_hippocampal_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampal head volume — — R²: 0.00649 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018415 PGS003673
(R_hippocampal_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampal body volume — — R²: 0.00706 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018416 PGS003674
(R_hippocampal_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampal head volume — — R²: 0.00511 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS005276 — — 200 individuals — African unspecified — UKB —
PSS005277 — — 113 individuals — East Asian — UKB —
PSS005278 — — 1,739 individuals — European non-white British ancestry UKB —
PSS005279 — — 328 individuals — South Asian — UKB —
PSS005280 — — 5,443 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS010958 — — 1,999 individuals — East Asian — CHIMGEN —