Trait: eating disorder

Experimental Factor Ontology (EFO) Information
Identifier EFO_0005203
Description A broad group of psychological disorders with abnormal eating behaviors leading to physiological effects from overeating or insufficient food intake. [NCIT: C89332]
Trait categories
Metabolic disorder
Neurological disorder
Synonyms 2 synonyms
  • eating disorder
  • feeding and eating disorder
Mapped terms 13 mapped terms
  • DOID:8670
  • ICD10:F50
  • ICD9:307.50
  • ICD9:307.59
  • MEDGEN:4434
  • MONDO:0005451
  • MedDRA:10014062
  • MedDRA:10014066
  • NCIT:C89332
  • NCIt:C89332
  • SCTID:72366004
  • SNOMEDCT:72366004
  • UMLS:C0013473

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002098
(portability-ldpred2_abnormal_appetite)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Recent poor appetite or overeating eating disorder 764,146
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002098/ScoringFiles/PGS002098.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM011640 PGS002098
(portability-ldpred2_abnormal_appetite)
 PSS009381|
European Ancestry|
6,451 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Recent poor appetite or overeating — — Partial Correlation (partial-r): 0.0629 [0.0385, 0.0872] sex, age, birth date, deprivation index, 16 PCs —
PPM011641 PGS002098
(portability-ldpred2_abnormal_appetite)
 PSS009155|
European Ancestry|
1,243 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Recent poor appetite or overeating — — Partial Correlation (partial-r): 0.1194 [0.0638, 0.1743] sex, age, birth date, deprivation index, 16 PCs —
PPM011642 PGS002098
(portability-ldpred2_abnormal_appetite)
 PSS008709|
European Ancestry|
2,260 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Recent poor appetite or overeating — — Partial Correlation (partial-r): 0.0823 [0.0411, 0.1233] sex, age, birth date, deprivation index, 16 PCs —
PPM011644 PGS002098
(portability-ldpred2_abnormal_appetite)
 PSS008261|
South Asian Ancestry|
814 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Recent poor appetite or overeating — — Partial Correlation (partial-r): 0.0558 [-0.0138, 0.1249] sex, age, birth date, deprivation index, 16 PCs —
PPM011645 PGS002098
(portability-ldpred2_abnormal_appetite)
 PSS008039|
East Asian Ancestry|
427 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Recent poor appetite or overeating — — Partial Correlation (partial-r): 0.0486 [-0.0488, 0.1451] sex, age, birth date, deprivation index, 16 PCs —
PPM011646 PGS002098
(portability-ldpred2_abnormal_appetite)
 PSS007825|
African Ancestry|
372 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Recent poor appetite or overeating — — Partial Correlation (partial-r): -0.0014 [-0.1059, 0.1032] sex, age, birth date, deprivation index, 16 PCs —
PPM011647 PGS002098
(portability-ldpred2_abnormal_appetite)
 PSS008929|
African Ancestry|
511 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Recent poor appetite or overeating — — Partial Correlation (partial-r): -0.014 [-0.1023, 0.0746] sex, age, birth date, deprivation index, 16 PCs —
PPM011643 PGS002098
(portability-ldpred2_abnormal_appetite)
 PSS008483|
Greater Middle Eastern Ancestry|
201 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Recent poor appetite or overeating — — Partial Correlation (partial-r): 0.1181 [-0.0282, 0.2595] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008709 — — 2,260 individuals — European Italy (South Europe) UKB —
PSS009381 — — 6,451 individuals — European UK (+ Ireland) UKB —
PSS008261 — — 814 individuals — South Asian India (South Asia) UKB —
PSS008039 — — 427 individuals — East Asian China (East Asia) UKB —
PSS008483 — — 201 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS007825 — — 372 individuals — African American or Afro-Caribbean Carribean UKB —
PSS008929 — — 511 individuals — African unspecified Nigeria (West Africa) UKB —
PSS009155 — — 1,243 individuals — European Poland (NE Europe) UKB —