Trait: grip strength measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0006941
Description quantification of the force applied by the hand to pull on or suspend from objects
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
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Polygenic Score ID & Name
PGS Publication ID (PGP)
Reported Trait
Mapped Trait(s) (Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS001119
(GBE_INI46)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Left hand grip strengthgrip strength measurement13,767
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001119/ScoringFiles/PGS001119.txt.gz
PGS001120
(GBE_INI47)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Right hand grip strengthgrip strength measurement12,644
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001120/ScoringFiles/PGS001120.txt.gz
PGS001927
(portability-PLR_hand_grip_strength)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Hand grip strength (mean of both)grip strength measurement73,846
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001927/ScoringFiles/PGS001927.txt.gz
PGS002143
(portability-ldpred2_hand_grip_strength)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Hand grip strength (mean of both)grip strength measurement966,283
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002143/ScoringFiles/PGS002143.txt.gz
PGS003513
(cont-decay-hand_grip_strength)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Hand grip strength (mean of both)grip strength measurement979,739
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003513/ScoringFiles/PGS003513.txt.gz
PGS004428
(X46.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Hand grip strength (left)grip strength measurement1,059,939
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004428/ScoringFiles/PGS004428.txt.gz
PGS004429
(X47.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Hand grip strength (right)grip strength measurement1,059,939
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004429/ScoringFiles/PGS004429.txt.gz
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
Evaluated Score
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM008333PGS001119
(GBE_INI46)
PSS007346|
African Ancestry|
6,406 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Hand grip strength (L): 0.46137 [0.44358, 0.47915]
Incremental R2 (full-covars): -0.00082
PGS R2 (no covariates): 0.00155 [-0.00036, 0.00346]
age, sex, UKB array type, Genotype PCs
PPM008334PGS001119
(GBE_INI46)
PSS007347|
East Asian Ancestry|
1,696 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Hand grip strength (L): 0.51785 [0.48497, 0.55073]
Incremental R2 (full-covars): 0.00522
PGS R2 (no covariates): 0.01076 [0.00104, 0.02048]
age, sex, UKB array type, Genotype PCs
PPM008335PGS001119
(GBE_INI46)
PSS007348|
European Ancestry|
24,787 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Hand grip strength (L): 0.54413 [0.53578, 0.55248]
Incremental R2 (full-covars): 0.01167
PGS R2 (no covariates): 0.01075 [0.0082, 0.01329]
age, sex, UKB array type, Genotype PCs
PPM008336PGS001119
(GBE_INI46)
PSS007349|
South Asian Ancestry|
7,727 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Hand grip strength (L): 0.48797 [0.47214, 0.50381]
Incremental R2 (full-covars): 0.00538
PGS R2 (no covariates): 0.00871 [0.00462, 0.01281]
age, sex, UKB array type, Genotype PCs
PPM008337PGS001119
(GBE_INI46)
PSS007350|
European Ancestry|
67,154 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Hand grip strength (L): 0.57766 [0.57281, 0.5825]
Incremental R2 (full-covars): 0.01506
PGS R2 (no covariates): 0.01441 [0.01262, 0.0162]
age, sex, UKB array type, Genotype PCs
PPM008338PGS001120
(GBE_INI47)
PSS007351|
African Ancestry|
6,401 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Hand grip strength (R): 0.46894 [0.45127, 0.48662]
Incremental R2 (full-covars): 0.00206
PGS R2 (no covariates): 0.00239 [0.00002, 0.00476]
age, sex, UKB array type, Genotype PCs
PPM008339PGS001120
(GBE_INI47)
PSS007352|
East Asian Ancestry|
1,696 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Hand grip strength (R): 0.52807 [0.49557, 0.56056]
Incremental R2 (full-covars): 0.00381
PGS R2 (no covariates): 0.00613 [-0.00124, 0.01351]
age, sex, UKB array type, Genotype PCs
PPM008340PGS001120
(GBE_INI47)
PSS007353|
European Ancestry|
24,789 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Hand grip strength (R): 0.55224 [0.54398, 0.5605]
Incremental R2 (full-covars): 0.01267
PGS R2 (no covariates): 0.01229 [0.00957, 0.01501]
age, sex, UKB array type, Genotype PCs
PPM008341PGS001120
(GBE_INI47)
PSS007354|
South Asian Ancestry|
7,741 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Hand grip strength (R): 0.48203 [0.46611, 0.49796]
Incremental R2 (full-covars): 0.00822
PGS R2 (no covariates): 0.00897 [0.00481, 0.01312]
age, sex, UKB array type, Genotype PCs
PPM008342PGS001120
(GBE_INI47)
PSS007355|
European Ancestry|
67,185 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Hand grip strength (R): 0.57637 [0.57152, 0.58123]
Incremental R2 (full-covars): 0.01651
PGS R2 (no covariates): 0.01531 [0.01347, 0.01715]
age, sex, UKB array type, Genotype PCs
PPM010291PGS001927
(portability-PLR_hand_grip_strength)
PSS009413|
European Ancestry|
19,855 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hand grip strength (mean of both)Partial Correlation (partial-r): 0.2515 [0.2384, 0.2645]sex, age, birth date, deprivation index, 16 PCs
PPM010292PGS001927
(portability-PLR_hand_grip_strength)
PSS009187|
European Ancestry|
4,105 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hand grip strength (mean of both)Partial Correlation (partial-r): 0.2485 [0.2195, 0.2771]sex, age, birth date, deprivation index, 16 PCs
PPM010293PGS001927
(portability-PLR_hand_grip_strength)
PSS008741|
European Ancestry|
6,598 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hand grip strength (mean of both)Partial Correlation (partial-r): 0.2292 [0.2062, 0.252]sex, age, birth date, deprivation index, 16 PCs
PPM010294PGS001927
(portability-PLR_hand_grip_strength)
PSS008515|
Greater Middle Eastern Ancestry|
1,168 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hand grip strength (mean of both)Partial Correlation (partial-r): 0.1973 [0.1411, 0.2523]sex, age, birth date, deprivation index, 16 PCs
PPM010295PGS001927
(portability-PLR_hand_grip_strength)
PSS008293|
South Asian Ancestry|
6,223 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Hand grip strength (mean of both)Partial Correlation (partial-r): 0.1688 [0.1445, 0.1929]sex, age, birth date, deprivation index, 16 PCs
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS0073466,406 individualsAfrican unspecifiedUKB
PSS0073471,696 individualsEast AsianUKB
PSS00734824,787 individualsEuropeannon-white British ancestryUKB
PSS0073497,727 individualsSouth AsianUKB
PSS00735067,154 individualsEuropeanwhite British ancestryUKBTesting cohort (heldout set)
PSS0073516,401 individualsAfrican unspecifiedUKB
PSS0073521,696 individualsEast AsianUKB
PSS00735324,789 individualsEuropeannon-white British ancestryUKB
PSS0073547,741 individualsSouth AsianUKB
PSS00735567,185 individualsEuropeanwhite British ancestryUKBTesting cohort (heldout set)
PSS0078572,448 individualsAfrican American or Afro-CaribbeanCarribeanUKB
PSS0080701,799 individualsEast AsianChina (East Asia)UKB
PSS0082936,223 individualsSouth AsianIndia (South Asia)UKB
PSS0085151,168 individualsGreater Middle Eastern (Middle Eastern, North African or Persian)Iran (Middle East)UKB
PSS0087416,598 individualsEuropeanItaly (South Europe)UKB
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