Trait: hair colour measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007822
Description quantification of some aspect of hair colour, such as whether greying occurs, how advanced greying is or qualification to what colour family hair belongs
Trait category
Other measurement
Mapped term PMID:26926045

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001092
(GBE_BIN_FC5001747)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hair color, black hair colour measurement 1,649
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001092/ScoringFiles/PGS001092.txt.gz
PGS001093
(GBE_BIN_FC1001747)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hair color, blonde hair colour measurement 6,970
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001093/ScoringFiles/PGS001093.txt.gz
PGS001094
(GBE_BIN_FC7001747)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hair color, brown hair colour measurement 4,024
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001094/ScoringFiles/PGS001094.txt.gz
PGS001095
(GBE_BIN_FC4001747)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hair color, dark brown hair colour measurement 5,662
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001095/ScoringFiles/PGS001095.txt.gz
PGS001096
(GBE_BIN_FC3001747)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hair color, light brown hair colour measurement 2,127
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001096/ScoringFiles/PGS001096.txt.gz
PGS001097
(GBE_BIN_FC6001747)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hair color, other hair colour measurement 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001097/ScoringFiles/PGS001097.txt.gz
PGS001098
(GBE_BIN_FC2001747)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hair color, red hair colour measurement 1,621
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001098/ScoringFiles/PGS001098.txt.gz
PGS001896
(portability-PLR_darker_hair0)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hair color (natural, before greying) hair colour measurement 31,036
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001896/ScoringFiles/PGS001896.txt.gz
PGS002002
(portability-PLR_red_hair)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hair color (natural, before greying) hair colour measurement 2,755
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002002/ScoringFiles/PGS002002.txt.gz
PGS002109
(portability-ldpred2_darker_hair0)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hair color (natural, before greying) hair colour measurement 393,500
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002109/ScoringFiles/PGS002109.txt.gz
PGS002220
(portability-ldpred2_red_hair)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hair color (natural, before greying) hair colour measurement 21,400
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002220/ScoringFiles/PGS002220.txt.gz
PGS002330
(pigment_HAIR.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hair color hair colour measurement 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002330/ScoringFiles/PGS002330.txt.gz
PGS002402
(pigment_HAIR.P+T.0.0001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hair color hair colour measurement 18,096
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002402/ScoringFiles/PGS002402.txt.gz
PGS002451
(pigment_HAIR.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hair color hair colour measurement 35,360
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002451/ScoringFiles/PGS002451.txt.gz
PGS002500
(pigment_HAIR.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hair color hair colour measurement 128,235
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002500/ScoringFiles/PGS002500.txt.gz
PGS002549
(pigment_HAIR.P+T.1e-06)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hair color hair colour measurement 10,216
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002549/ScoringFiles/PGS002549.txt.gz
PGS002598
(pigment_HAIR.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hair color hair colour measurement 8,312
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002598/ScoringFiles/PGS002598.txt.gz
PGS002647
(pigment_HAIR.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hair color hair colour measurement 143,829
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002647/ScoringFiles/PGS002647.txt.gz
PGS002696
(pigment_HAIR.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hair color hair colour measurement 924,497
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002696/ScoringFiles/PGS002696.txt.gz
PGS003496
(cont-decay-darker_hair0)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Hair color (natural, before greying) hair colour measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003496/ScoringFiles/PGS003496.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM008203 PGS001092
(GBE_BIN_FC5001747)
 PSS003969|
African Ancestry|
6,395 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) black — AUROC: 0.73806 [0.72041, 0.75572] R²: 0.15759
Incremental AUROC (full-covars): -0.00158
PGS R2 (no covariates): 0.06773
PGS AUROC (no covariates): 0.64443 [0.62282, 0.66604]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008204 PGS001092
(GBE_BIN_FC5001747)
 PSS003970|
East Asian Ancestry|
1,668 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) black — AUROC: 0.64698 [0.61512, 0.67883] R²: 0.06317
Incremental AUROC (full-covars): -0.01356
PGS R2 (no covariates): 0.00159
PGS AUROC (no covariates): 0.51653 [0.48088, 0.55219]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008205 PGS001092
(GBE_BIN_FC5001747)
 PSS003971|
European Ancestry|
24,865 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) black — AUROC: 0.86644 [0.85917, 0.87371] R²: 0.31811
Incremental AUROC (full-covars): 0.10937
PGS R2 (no covariates): 0.25773
PGS AUROC (no covariates): 0.83509 [0.82689, 0.84329]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008206 PGS001092
(GBE_BIN_FC5001747)
 PSS003972|
South Asian Ancestry|
7,652 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) black — AUROC: 0.73447 [0.7223, 0.74664] R²: 0.19134
Incremental AUROC (full-covars): -0.00772
PGS R2 (no covariates): 0.03493
PGS AUROC (no covariates): 0.59358 [0.57931, 0.60784]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008207 PGS001092
(GBE_BIN_FC5001747)
 PSS003973|
European Ancestry|
67,286 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) black — AUROC: 0.88391 [0.87857, 0.88926] R²: 0.30488
Incremental AUROC (full-covars): 0.14967
PGS R2 (no covariates): 0.21551
PGS AUROC (no covariates): 0.83054 [0.82335, 0.83772]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008208 PGS001093
(GBE_BIN_FC1001747)
 PSS003747|
European Ancestry|
24,865 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) blonde — AUROC: 0.8629 [0.85606, 0.86974] R²: 0.35705
Incremental AUROC (full-covars): 0.14577
PGS R2 (no covariates): 0.35919
PGS AUROC (no covariates): 0.86449 [0.85779, 0.87119]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008209 PGS001093
(GBE_BIN_FC1001747)
 PSS003748|
South Asian Ancestry|
7,652 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) blonde — AUROC: 0.72231 [0.56379, 0.88083] R²: 0.07035
Incremental AUROC (full-covars): -0.06225
PGS R2 (no covariates): 0.01842
PGS AUROC (no covariates): 0.60036 [0.44104, 0.75968]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008210 PGS001093
(GBE_BIN_FC1001747)
 PSS003749|
European Ancestry|
67,286 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) blonde — AUROC: 0.84642 [0.84221, 0.85062] R²: 0.32199
Incremental AUROC (full-covars): 0.28973
PGS R2 (no covariates): 0.32399
PGS AUROC (no covariates): 0.84754 [0.84337, 0.85171]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008211 PGS001094
(GBE_BIN_FC7001747)
 PSS004004|
African Ancestry|
6,395 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) brown — AUROC: 0.71768 [0.69956, 0.7358] R²: 0.12623
Incremental AUROC (full-covars): -0.03583
PGS R2 (no covariates): 0.03239
PGS AUROC (no covariates): 0.39864 [0.37618, 0.42109]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008212 PGS001094
(GBE_BIN_FC7001747)
 PSS004005|
East Asian Ancestry|
1,668 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) brown — AUROC: 0.65007 [0.61813, 0.68201] R²: 0.07693
Incremental AUROC (full-covars): -0.01602
PGS R2 (no covariates): 0.00012
PGS AUROC (no covariates): 0.49459 [0.45931, 0.52988]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008213 PGS001094
(GBE_BIN_FC7001747)
 PSS004006|
European Ancestry|
24,865 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) brown — AUROC: 0.63987 [0.63123, 0.64851] R²: 0.07778
Incremental AUROC (full-covars): 0.06751
PGS R2 (no covariates): 0.06909
PGS AUROC (no covariates): 0.62444 [0.61553, 0.63335]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008214 PGS001094
(GBE_BIN_FC7001747)
 PSS004007|
South Asian Ancestry|
7,652 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) brown — AUROC: 0.71561 [0.70281, 0.7284] R²: 0.16063
Incremental AUROC (full-covars): -0.03646
PGS R2 (no covariates): 0.02063
PGS AUROC (no covariates): 0.42996 [0.41544, 0.44447]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008215 PGS001094
(GBE_BIN_FC7001747)
 PSS004008|
European Ancestry|
67,286 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) brown — AUROC: 0.69817 [0.69293, 0.70341] R²: 0.14719
Incremental AUROC (full-covars): 0.16012
PGS R2 (no covariates): 0.14428
PGS AUROC (no covariates): 0.69511 [0.68976, 0.70046]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008216 PGS001095
(GBE_BIN_FC4001747)
 PSS003934|
African Ancestry|
6,395 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) dark brown — AUROC: 0.65156 [0.63203, 0.67109] R²: 0.05774
Incremental AUROC (full-covars): -0.10551
PGS R2 (no covariates): 0.06147
PGS AUROC (no covariates): 0.36004 [0.33679, 0.38329]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008217 PGS001095
(GBE_BIN_FC4001747)
 PSS003935|
East Asian Ancestry|
1,668 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) dark brown — AUROC: 0.61634 [0.58316, 0.64951] R²: 0.04892
Incremental AUROC (full-covars): -0.04911
PGS R2 (no covariates): 0.00247
PGS AUROC (no covariates): 0.46704 [0.43121, 0.50287]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008218 PGS001095
(GBE_BIN_FC4001747)
 PSS003936|
European Ancestry|
24,865 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) dark brown — AUROC: 0.73384 [0.7277, 0.73998] R²: 0.17609
Incremental AUROC (full-covars): 0.13518
PGS R2 (no covariates): 0.18215
PGS AUROC (no covariates): 0.73591 [0.72979, 0.74203]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008219 PGS001095
(GBE_BIN_FC4001747)
 PSS003937|
South Asian Ancestry|
7,652 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) dark brown — AUROC: 0.6651 [0.65094, 0.67927] R²: 0.08302
Incremental AUROC (full-covars): -0.08617
PGS R2 (no covariates): 0.02576
PGS AUROC (no covariates): 0.41252 [0.3978, 0.42725]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008220 PGS001095
(GBE_BIN_FC4001747)
 PSS003938|
European Ancestry|
67,286 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) dark brown — AUROC: 0.77552 [0.77202, 0.77902] R²: 0.26416
Incremental AUROC (full-covars): 0.24306
PGS R2 (no covariates): 0.26448
PGS AUROC (no covariates): 0.77588 [0.77238, 0.77938]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008221 PGS001096
(GBE_BIN_FC3001747)
 PSS003894|
African Ancestry|
6,395 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) light brown — AUROC: 0.74239 [0.6665, 0.81828] R²: 0.10516
Incremental AUROC (full-covars): 0.00443
PGS R2 (no covariates): 0.03054
PGS AUROC (no covariates): 0.59019 [0.48973, 0.69066]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008222 PGS001096
(GBE_BIN_FC3001747)
 PSS003895|
East Asian Ancestry|
1,668 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) light brown — AUROC: 0.7191 [0.5714, 0.86681] R²: 0.05082
Incremental AUROC (full-covars): 0.01726
PGS R2 (no covariates): 7e-05
PGS AUROC (no covariates): 0.5472 [0.40687, 0.68753]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008223 PGS001096
(GBE_BIN_FC3001747)
 PSS003896|
European Ancestry|
24,865 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) light brown — AUROC: 0.64374 [0.63684, 0.65063] R²: 0.08084
Incremental AUROC (full-covars): 0.08241
PGS R2 (no covariates): 0.08583
PGS AUROC (no covariates): 0.6467 [0.63984, 0.65355]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008224 PGS001096
(GBE_BIN_FC3001747)
 PSS003897|
South Asian Ancestry|
7,652 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) light brown — AUROC: 0.6965 [0.65927, 0.73373] R²: 0.0697
Incremental AUROC (full-covars): 0.04422
PGS R2 (no covariates): 0.04452
PGS AUROC (no covariates): 0.64901 [0.60792, 0.69011]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008225 PGS001096
(GBE_BIN_FC3001747)
 PSS003898|
European Ancestry|
67,286 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) light brown — AUROC: 0.63678 [0.63262, 0.64093] R²: 0.07841
Incremental AUROC (full-covars): 0.10619
PGS R2 (no covariates): 0.0774
PGS AUROC (no covariates): 0.63449 [0.63034, 0.63865]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008226 PGS001097
(GBE_BIN_FC6001747)
 PSS003984|
African Ancestry|
6,395 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) other — AUROC: 0.68416 [0.60178, 0.76653] R²: 0.04963
Incremental AUROC (full-covars): 0.00247
PGS R2 (no covariates): 0.00135
PGS AUROC (no covariates): 0.53686 [0.45932, 0.6144]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008227 PGS001097
(GBE_BIN_FC6001747)
 PSS003985|
East Asian Ancestry|
1,668 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) other — AUROC: 0.85339 [0.78314, 0.92364] R²: 0.12305
Incremental AUROC (full-covars): -0.00248
PGS R2 (no covariates): 0.00835
PGS AUROC (no covariates): 0.40595 [0.19292, 0.61897]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008228 PGS001097
(GBE_BIN_FC6001747)
 PSS003986|
European Ancestry|
24,865 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) other — AUROC: 0.65979 [0.63012, 0.68946] R²: 0.03266
Incremental AUROC (full-covars): 0.01921
PGS R2 (no covariates): 0.0114
PGS AUROC (no covariates): 0.59367 [0.56236, 0.62499]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008229 PGS001097
(GBE_BIN_FC6001747)
 PSS003987|
South Asian Ancestry|
7,652 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) other — AUROC: 0.77253 [0.71966, 0.82541] R²: 0.09785
Incremental AUROC (full-covars): 0.00187
PGS R2 (no covariates): 0.00125
PGS AUROC (no covariates): 0.52534 [0.46064, 0.59004]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008230 PGS001097
(GBE_BIN_FC6001747)
 PSS003988|
European Ancestry|
67,286 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) other — AUROC: 0.66009 [0.64226, 0.67793] R²: 0.03193
Incremental AUROC (full-covars): 0.02994
PGS R2 (no covariates): 0.01286
PGS AUROC (no covariates): 0.59773 [0.57827, 0.61719]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008231 PGS001098
(GBE_BIN_FC2001747)
 PSS003840|
African Ancestry|
6,395 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) red — AUROC: 0.66297 [0.41942, 0.90653] R²: 0.03161
Incremental AUROC (full-covars): -0.14372
PGS R2 (no covariates): 0.01304
PGS AUROC (no covariates): 0.33718 [0.05268, 0.62169]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008232 PGS001098
(GBE_BIN_FC2001747)
 PSS003841|
European Ancestry|
24,865 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) red — AUROC: 0.95374 [0.94735, 0.96013] R²: 0.57916
Incremental AUROC (full-covars): 0.27252
PGS R2 (no covariates): 0.58427
PGS AUROC (no covariates): 0.95332 [0.94681, 0.95982]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008233 PGS001098
(GBE_BIN_FC2001747)
 PSS003843|
European Ancestry|
67,286 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hair colour (natural, before greying) red — AUROC: 0.96093 [0.95755, 0.96431] R²: 0.60335
Incremental AUROC (full-covars): 0.3903
PGS R2 (no covariates): 0.60185
PGS AUROC (no covariates): 0.96068 [0.95728, 0.96408]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM010051 PGS001896
(portability-PLR_darker_hair0)
 PSS009392|
European Ancestry|
18,840 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.5035 [0.4927, 0.514] sex, age, birth date, deprivation index, 16 PCs —
PPM010052 PGS001896
(portability-PLR_darker_hair0)
 PSS009166|
European Ancestry|
3,985 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.4762 [0.4517, 0.4999] sex, age, birth date, deprivation index, 16 PCs —
PPM010053 PGS001896
(portability-PLR_darker_hair0)
 PSS008720|
European Ancestry|
6,455 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.4084 [0.3879, 0.4286] sex, age, birth date, deprivation index, 16 PCs —
PPM010054 PGS001896
(portability-PLR_darker_hair0)
 PSS008494|
Greater Middle Eastern Ancestry|
1,131 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.2787 [0.2235, 0.3321] sex, age, birth date, deprivation index, 16 PCs —
PPM010055 PGS001896
(portability-PLR_darker_hair0)
 PSS008272|
South Asian Ancestry|
6,130 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.1041 [0.0792, 0.1288] sex, age, birth date, deprivation index, 16 PCs —
PPM010056 PGS001896
(portability-PLR_darker_hair0)
 PSS008049|
East Asian Ancestry|
1,782 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.0247 [-0.0221, 0.0713] sex, age, birth date, deprivation index, 16 PCs —
PPM010057 PGS001896
(portability-PLR_darker_hair0)
 PSS007836|
African Ancestry|
2,414 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.0902 [0.0504, 0.1298] sex, age, birth date, deprivation index, 16 PCs —
PPM010058 PGS001896
(portability-PLR_darker_hair0)
 PSS008940|
African Ancestry|
3,832 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.0274 [-0.0044, 0.0591] sex, age, birth date, deprivation index, 16 PCs —
PPM010892 PGS002002
(portability-PLR_red_hair)
 PSS009260|
European Ancestry|
4,046 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.3044 [0.2761, 0.3322] sex, age, birth date, deprivation index, 16 PCs —
PPM010893 PGS002002
(portability-PLR_red_hair)
 PSS008814|
European Ancestry|
6,570 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.29 [0.2676, 0.312] sex, age, birth date, deprivation index, 16 PCs —
PPM010894 PGS002002
(portability-PLR_red_hair)
 PSS008588|
Greater Middle Eastern Ancestry|
1,135 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.2119 [0.1551, 0.2673] sex, age, birth date, deprivation index, 16 PCs —
PPM010895 PGS002002
(portability-PLR_red_hair)
 PSS008366|
South Asian Ancestry|
6,131 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.0255 sex, age, birth date, deprivation index, 16 PCs —
PPM010896 PGS002002
(portability-PLR_red_hair)
 PSS007930|
African Ancestry|
2,419 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): -0.0053 [-0.0453, 0.0347] sex, age, birth date, deprivation index, 16 PCs —
PPM010897 PGS002002
(portability-PLR_red_hair)
 PSS009034|
African Ancestry|
3,836 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): -0.0153 [-0.0471, 0.0164] sex, age, birth date, deprivation index, 16 PCs —
PPM010891 PGS002002
(portability-PLR_red_hair)
 PSS009486|
European Ancestry|
19,713 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.4238 [0.4123, 0.4352] sex, age, birth date, deprivation index, 16 PCs —
PPM011727 PGS002109
(portability-ldpred2_darker_hair0)
 PSS009392|
European Ancestry|
18,840 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.4937 [0.4828, 0.5044] sex, age, birth date, deprivation index, 16 PCs —
PPM011728 PGS002109
(portability-ldpred2_darker_hair0)
 PSS009166|
European Ancestry|
3,985 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.4622 [0.4373, 0.4863] sex, age, birth date, deprivation index, 16 PCs —
PPM011729 PGS002109
(portability-ldpred2_darker_hair0)
 PSS008720|
European Ancestry|
6,455 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.3957 [0.3749, 0.4161] sex, age, birth date, deprivation index, 16 PCs —
PPM011730 PGS002109
(portability-ldpred2_darker_hair0)
 PSS008494|
Greater Middle Eastern Ancestry|
1,131 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.2705 [0.2152, 0.3242] sex, age, birth date, deprivation index, 16 PCs —
PPM011731 PGS002109
(portability-ldpred2_darker_hair0)
 PSS008272|
South Asian Ancestry|
6,130 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.1004 [0.0755, 0.1251] sex, age, birth date, deprivation index, 16 PCs —
PPM011732 PGS002109
(portability-ldpred2_darker_hair0)
 PSS008049|
East Asian Ancestry|
1,782 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.0167 [-0.03, 0.0634] sex, age, birth date, deprivation index, 16 PCs —
PPM011733 PGS002109
(portability-ldpred2_darker_hair0)
 PSS007836|
African Ancestry|
2,414 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.1104 [0.0706, 0.1498] sex, age, birth date, deprivation index, 16 PCs —
PPM011734 PGS002109
(portability-ldpred2_darker_hair0)
 PSS008940|
African Ancestry|
3,832 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.0397 [0.0079, 0.0713] sex, age, birth date, deprivation index, 16 PCs —
PPM012607 PGS002220
(portability-ldpred2_red_hair)
 PSS009486|
European Ancestry|
19,713 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.4428 [0.4315, 0.454] sex, age, birth date, deprivation index, 16 PCs —
PPM012608 PGS002220
(portability-ldpred2_red_hair)
 PSS009260|
European Ancestry|
4,046 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.3315 [0.3037, 0.3587] sex, age, birth date, deprivation index, 16 PCs —
PPM012609 PGS002220
(portability-ldpred2_red_hair)
 PSS008814|
European Ancestry|
6,570 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.3267 [0.3049, 0.3481] sex, age, birth date, deprivation index, 16 PCs —
PPM012610 PGS002220
(portability-ldpred2_red_hair)
 PSS008588|
Greater Middle Eastern Ancestry|
1,135 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.319 [0.2653, 0.3708] sex, age, birth date, deprivation index, 16 PCs —
PPM012611 PGS002220
(portability-ldpred2_red_hair)
 PSS008366|
South Asian Ancestry|
6,131 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): 0.041 [0.016, 0.066] sex, age, birth date, deprivation index, 16 PCs —
PPM012612 PGS002220
(portability-ldpred2_red_hair)
 PSS007930|
African Ancestry|
2,419 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): -0.0113 [-0.0513, 0.0287] sex, age, birth date, deprivation index, 16 PCs —
PPM012613 PGS002220
(portability-ldpred2_red_hair)
 PSS009034|
African Ancestry|
3,836 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hair colour (natural, before greying) — — Partial Correlation (partial-r): -0.0283 [-0.06, 0.0034] sex, age, birth date, deprivation index, 16 PCs —
PPM013095 PGS002330
(pigment_HAIR.BOLT-LMM)
 PSS009763|
African Ancestry|
6,421 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0109 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013144 PGS002330
(pigment_HAIR.BOLT-LMM)
 PSS009764|
East Asian Ancestry|
916 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0005 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013193 PGS002330
(pigment_HAIR.BOLT-LMM)
 PSS009765|
European Ancestry|
42,940 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.3021 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013242 PGS002330
(pigment_HAIR.BOLT-LMM)
 PSS009766|
South Asian Ancestry|
7,961 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0213 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013383 PGS002402
(pigment_HAIR.P+T.0.0001)
 PSS009763|
African Ancestry|
6,421 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0059 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013432 PGS002402
(pigment_HAIR.P+T.0.0001)
 PSS009764|
East Asian Ancestry|
916 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013481 PGS002402
(pigment_HAIR.P+T.0.0001)
 PSS009765|
European Ancestry|
42,940 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.1814 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013530 PGS002402
(pigment_HAIR.P+T.0.0001)
 PSS009766|
South Asian Ancestry|
7,961 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.014 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013579 PGS002451
(pigment_HAIR.P+T.0.001)
 PSS009763|
African Ancestry|
6,421 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0054 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013628 PGS002451
(pigment_HAIR.P+T.0.001)
 PSS009764|
East Asian Ancestry|
916 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013677 PGS002451
(pigment_HAIR.P+T.0.001)
 PSS009765|
European Ancestry|
42,940 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.1777 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013726 PGS002451
(pigment_HAIR.P+T.0.001)
 PSS009766|
South Asian Ancestry|
7,961 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0137 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013775 PGS002500
(pigment_HAIR.P+T.0.01)
 PSS009763|
African Ancestry|
6,421 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0026 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013824 PGS002500
(pigment_HAIR.P+T.0.01)
 PSS009764|
East Asian Ancestry|
916 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0011 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013873 PGS002500
(pigment_HAIR.P+T.0.01)
 PSS009765|
European Ancestry|
42,940 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.1522 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013922 PGS002500
(pigment_HAIR.P+T.0.01)
 PSS009766|
South Asian Ancestry|
7,961 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0025 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013971 PGS002549
(pigment_HAIR.P+T.1e-06)
 PSS009763|
African Ancestry|
6,421 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0073 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014020 PGS002549
(pigment_HAIR.P+T.1e-06)
 PSS009764|
East Asian Ancestry|
916 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014069 PGS002549
(pigment_HAIR.P+T.1e-06)
 PSS009765|
European Ancestry|
42,940 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.1828 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014118 PGS002549
(pigment_HAIR.P+T.1e-06)
 PSS009766|
South Asian Ancestry|
7,961 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.014 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014167 PGS002598
(pigment_HAIR.P+T.5e-08)
 PSS009763|
African Ancestry|
6,421 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0074 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014216 PGS002598
(pigment_HAIR.P+T.5e-08)
 PSS009764|
East Asian Ancestry|
916 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014265 PGS002598
(pigment_HAIR.P+T.5e-08)
 PSS009765|
European Ancestry|
42,940 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.1815 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014314 PGS002598
(pigment_HAIR.P+T.5e-08)
 PSS009766|
South Asian Ancestry|
7,961 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0135 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014363 PGS002647
(pigment_HAIR.PolyFun-pred)
 PSS009763|
African Ancestry|
6,421 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0219 age, sex, age*sex, assessment center, genotyping array, 10 PCs See pigment_HAIR.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014412 PGS002647
(pigment_HAIR.PolyFun-pred)
 PSS009764|
East Asian Ancestry|
916 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0095 age, sex, age*sex, assessment center, genotyping array, 10 PCs See pigment_HAIR.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014461 PGS002647
(pigment_HAIR.PolyFun-pred)
 PSS009765|
European Ancestry|
42,940 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.3269 age, sex, age*sex, assessment center, genotyping array, 10 PCs See pigment_HAIR.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014510 PGS002647
(pigment_HAIR.PolyFun-pred)
 PSS009766|
South Asian Ancestry|
7,961 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0303 age, sex, age*sex, assessment center, genotyping array, 10 PCs See pigment_HAIR.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014559 PGS002696
(pigment_HAIR.SBayesR)
 PSS009763|
African Ancestry|
6,421 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0012 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014608 PGS002696
(pigment_HAIR.SBayesR)
 PSS009764|
East Asian Ancestry|
916 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.002 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014657 PGS002696
(pigment_HAIR.SBayesR)
 PSS009765|
European Ancestry|
42,940 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.2525 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014706 PGS002696
(pigment_HAIR.SBayesR)
 PSS009766|
South Asian Ancestry|
7,961 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hair Color — — Incremental R2 (full model vs. covariates alone): 0.0161 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM017508 PGS003496
(cont-decay-darker_hair0)
 PSS010841|
European Ancestry|
3,986 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hair colour (natural, before greying) — — partial-R2: 0.24 sex, age, deprivation index, PC1-16 —
PPM017592 PGS003496
(cont-decay-darker_hair0)
 PSS010673|
European Ancestry|
6,316 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hair colour (natural, before greying) — — partial-R2: 0.12 sex, age, deprivation index, PC1-16 —
PPM017760 PGS003496
(cont-decay-darker_hair0)
 PSS010253|
European Ancestry|
2,281 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hair colour (natural, before greying) — — partial-R2: 0.16 sex, age, deprivation index, PC1-16 —
PPM017844 PGS003496
(cont-decay-darker_hair0)
 PSS010505|
South Asian Ancestry|
6,130 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hair colour (natural, before greying) — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM018096 PGS003496
(cont-decay-darker_hair0)
 PSS010757|
African Ancestry|
3,832 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hair colour (natural, before greying) — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017424 PGS003496
(cont-decay-darker_hair0)
 PSS010925|
European Ancestry|
18,819 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hair colour (natural, before greying) — — partial-R2: 0.28 sex, age, deprivation index, PC1-16 —
PPM017676 PGS003496
(cont-decay-darker_hair0)
 PSS010589|
Greater Middle Eastern Ancestry|
1,132 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hair colour (natural, before greying) — — partial-R2: 0.09 sex, age, deprivation index, PC1-16 —
PPM017928 PGS003496
(cont-decay-darker_hair0)
 PSS010421|
East Asian Ancestry|
1,785 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hair colour (natural, before greying) — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM018012 PGS003496
(cont-decay-darker_hair0)
 PSS010337|
African Ancestry|
2,414 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Hair colour (natural, before greying) — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009034 — — 3,836 individuals — African unspecified Nigeria (West Africa) UKB —
PSS009166 — — 3,985 individuals — European Poland (NE Europe) UKB —
PSS008272 — — 6,130 individuals — South Asian India (South Asia) UKB —
PSS010925 — — 18,819 individuals,
46.0 % Male samples
 Mean = 56.9 years
Sd = 7.9 years		 European white British UKB —
PSS010673 — — 6,316 individuals,
45.0 % Male samples
 Mean = 54.5 years
Sd = 8.4 years		 European Italian UKB —
PSS009763 — — 6,421 individuals — African unspecified — UKB —
PSS009764 — — 916 individuals — East Asian — UKB —
PSS009765 — — 42,940 individuals — European Non-British European UKB —
PSS009766 — — 7,961 individuals — South Asian — UKB —
PSS010757 — — 3,832 individuals,
46.0 % Male samples
 Mean = 51.9 years
Sd = 8.1 years		 African unspecified Nigerian UKB —
PSS010421 — — 1,785 individuals,
33.0 % Male samples
 Mean = 52.4 years
Sd = 7.8 years		 East Asian Chinese UKB —
PSS003934 — —
[
  • 712 cases
  • , 5,683 controls
]
 — African unspecified — UKB —
PSS003935 — —
[
  • 295 cases
  • , 1,373 controls
]
 — East Asian — UKB —
PSS003936 — —
[
  • 9,961 cases
  • , 14,904 controls
]
 — European non-white British ancestry UKB —
PSS003937 — —
[
  • 1,887 cases
  • , 5,765 controls
]
 — South Asian — UKB —
PSS003938 — —
[
  • 25,313 cases
  • , 41,973 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS008940 — — 3,832 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008814 — — 6,570 individuals — European Italy (South Europe) UKB —
PSS008049 — — 1,782 individuals — East Asian China (East Asia) UKB —
PSS007930 — — 2,419 individuals — African American or Afro-Caribbean Carribean UKB —
PSS010841 — — 3,986 individuals,
37.0 % Male samples
 Mean = 54.4 years
Sd = 7.6 years		 European Polish UKB —
PSS010589 — — 1,132 individuals,
59.0 % Male samples
 Mean = 52.1 years
Sd = 8.0 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010337 — — 2,414 individuals,
36.0 % Male samples
 Mean = 52.4 years
Sd = 8.0 years		 African American or Afro-Caribbean Caribbean UKB —
PSS003840 — —
[
  • 5 cases
  • , 6,390 controls
]
 — African unspecified — UKB —
PSS003969 — —
[
  • 5,590 cases
  • , 805 controls
]
 — African unspecified — UKB —
PSS003970 — —
[
  • 1,360 cases
  • , 308 controls
]
 — East Asian — UKB —
PSS003971 — —
[
  • 1,986 cases
  • , 22,879 controls
]
 — European non-white British ancestry UKB —
PSS003972 — —
[
  • 5,499 cases
  • , 2,153 controls
]
 — South Asian — UKB —
PSS003973 — —
[
  • 2,842 cases
  • , 64,444 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS003841 — —
[
  • 1,124 cases
  • , 23,741 controls
]
 — European non-white British ancestry UKB —
PSS003843 — —
[
  • 3,058 cases
  • , 64,228 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS008720 — — 6,455 individuals — European Italy (South Europe) UKB —
PSS008588 — — 1,135 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009486 — — 19,713 individuals — European UK (+ Ireland) UKB —
PSS003984 — —
[
  • 55 cases
  • , 6,340 controls
]
 — African unspecified — UKB —
PSS003985 — —
[
  • 8 cases
  • , 1,660 controls
]
 — East Asian — UKB —
PSS003986 — —
[
  • 314 cases
  • , 24,551 controls
]
 — European non-white British ancestry UKB —
PSS003987 — —
[
  • 76 cases
  • , 7,576 controls
]
 — South Asian — UKB —
PSS003988 — —
[
  • 856 cases
  • , 66,430 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS007836 — — 2,414 individuals — African American or Afro-Caribbean Carribean UKB —
PSS003747 — —
[
  • 2,765 cases
  • , 22,100 controls
]
 — European non-white British ancestry UKB —
PSS003748 — —
[
  • 11 cases
  • , 7,641 controls
]
 — South Asian — UKB —
PSS003749 — —
[
  • 7,914 cases
  • , 59,372 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004004 — —
[
  • 753 cases
  • , 5,642 controls
]
 — African unspecified — UKB —
PSS004005 — —
[
  • 307 cases
  • , 1,361 controls
]
 — East Asian — UKB —
PSS004006 — —
[
  • 18,755 cases
  • , 6,110 controls
]
 — European non-white British ancestry UKB —
PSS004007 — —
[
  • 2,087 cases
  • , 5,565 controls
]
 — South Asian — UKB —
PSS004008 — —
[
  • 52,905 cases
  • , 14,381 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS009392 — — 18,840 individuals — European UK (+ Ireland) UKB —
PSS008494 — — 1,131 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009260 — — 4,046 individuals — European Poland (NE Europe) UKB —
PSS008366 — — 6,131 individuals — South Asian India (South Asia) UKB —
PSS010253 — — 2,281 individuals,
45.0 % Male samples
 Mean = 58.0 years
Sd = 7.1 years		 European Ashkenazi UKB —
PSS010505 — — 6,130 individuals,
54.0 % Male samples
 Mean = 53.2 years
Sd = 8.4 years		 South Asian Indian UKB —
PSS003894 — —
[
  • 41 cases
  • , 6,354 controls
]
 — African unspecified — UKB —
PSS003895 — —
[
  • 12 cases
  • , 1,656 controls
]
 — East Asian — UKB —
PSS003896 — —
[
  • 8,887 cases
  • , 15,978 controls
]
 — European non-white British ancestry UKB —
PSS003897 — —
[
  • 201 cases
  • , 7,451 controls
]
 — South Asian — UKB —
PSS003898 — —
[
  • 27,978 cases
  • , 39,308 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)