Trait: heel bone mineral density

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009270
Description Quantification of the mineral density of the heel bone
Trait category
Other measurement
Mapped term PMID:28869591

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001037
(GBE_INI78)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heel bone mineral density (BMD) T-score, automated heel bone mineral density 14,310
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001037/ScoringFiles/PGS001037.txt.gz
PGS001038
(GBE_INI4106)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Left heel bone mineral density (BMD) T-score, automated heel bone mineral density 9,275
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001038/ScoringFiles/PGS001038.txt.gz
PGS001039
(GBE_INI4125)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Right heel bone mineral density (BMD) T-score, automated heel bone mineral density 9,753
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001039/ScoringFiles/PGS001039.txt.gz
PGS001402
(GBE_INI3148)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heel bone mineral density (BMD) heel bone mineral density 14,251
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001402/ScoringFiles/PGS001402.txt.gz
PGS001403
(GBE_INI4105)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heel bone mineral density (BMD) (L) heel bone mineral density 8,285
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001403/ScoringFiles/PGS001403.txt.gz
PGS001404
(GBE_INI4124)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heel bone mineral density (BMD) (R) heel bone mineral density 9,637
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001404/ScoringFiles/PGS001404.txt.gz
PGS001955
(portability-PLR_log_heel_BMD)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Heel bone mineral density (BMD) heel bone mineral density 73,565
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001955/ScoringFiles/PGS001955.txt.gz
PGS002173
(portability-ldpred2_log_heel_BMD)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Heel bone mineral density (BMD) heel bone mineral density 729,074
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002173/ScoringFiles/PGS002173.txt.gz
PGS002768
(BMD_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Osteoporosis osteoporosis,
heel bone mineral density		 1,091,549
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002768/ScoringFiles/PGS002768.txt.gz
PGS003535
(cont-decay-log_heel_BMD)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Heel bone mineral density (BMD) heel bone mineral density 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003535/ScoringFiles/PGS003535.txt.gz
PGS004411
(X78.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel bone mineral density (BMD) T-score, automated heel bone mineral density 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004411/ScoringFiles/PGS004411.txt.gz
PGS004415
(X3148.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel bone mineral density (BMD) heel bone mineral density 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004415/ScoringFiles/PGS004415.txt.gz
PGS004419
(X4105.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel bone mineral density (BMD) (left) heel bone mineral density 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004419/ScoringFiles/PGS004419.txt.gz
PGS004420
(X4106.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel bone mineral density (BMD) T-score, automated (left) heel bone mineral density 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004420/ScoringFiles/PGS004420.txt.gz
PGS004424
(X4124.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel bone mineral density (BMD) (right) heel bone mineral density 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004424/ScoringFiles/PGS004424.txt.gz
PGS004425
(X4125.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Heel bone mineral density (BMD) T-score, automated (right) heel bone mineral density 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004425/ScoringFiles/PGS004425.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007945 PGS001037
(GBE_INI78)
 PSS007478|
European Ancestry|
12,376 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated — — R²: 0.1881 [0.17936, 0.19685]
Incremental R2 (full-covars): 0.13506
PGS R2 (no covariates): 0.13678 [0.12885, 0.14471]		 age, sex, UKB array type, Genotype PCs —
PPM007943 PGS001037
(GBE_INI78)
 PSS007476|
African Ancestry|
2,253 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated — — R²: 0.0346 [0.02587, 0.04333]
Incremental R2 (full-covars): 0.01755
PGS R2 (no covariates): 0.01827 [0.01182, 0.02472]		 age, sex, UKB array type, Genotype PCs —
PPM007944 PGS001037
(GBE_INI78)
 PSS007477|
East Asian Ancestry|
795 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated — — Incremental R2 (full-covars): 0.06623
R²: 0.09833 [0.07154, 0.12513]
PGS R2 (no covariates): 0.06929 [0.04608, 0.09251]		 age, sex, UKB array type, Genotype PCs —
PPM007946 PGS001037
(GBE_INI78)
 PSS007479|
South Asian Ancestry|
2,312 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated — — R²: 0.10193 [0.08923, 0.11462]
Incremental R2 (full-covars): 0.06757
PGS R2 (no covariates): 0.07119 [0.06021, 0.08216]		 age, sex, UKB array type, Genotype PCs —
PPM007947 PGS001037
(GBE_INI78)
 PSS007480|
European Ancestry|
38,834 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated — — R²: 0.19661 [0.19123, 0.20198]
Incremental R2 (full-covars): 0.1419
PGS R2 (no covariates): 0.14159 [0.13671, 0.14646]		 age, sex, UKB array type, Genotype PCs —
PPM007948 PGS001038
(GBE_INI4106)
 PSS007296|
African Ancestry|
3,560 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (L) — — R²: 0.02571 [0.01812, 0.03331]
Incremental R2 (full-covars): 0.00529
PGS R2 (no covariates): 0.00688 [0.00288, 0.01089]		 age, sex, UKB array type, Genotype PCs —
PPM007949 PGS001038
(GBE_INI4106)
 PSS007297|
East Asian Ancestry|
781 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (L) — — R²: 0.10298 [0.0757, 0.13026]
Incremental R2 (full-covars): 0.08297
PGS R2 (no covariates): 0.082 [0.05709, 0.10691]		 age, sex, UKB array type, Genotype PCs —
PPM007950 PGS001038
(GBE_INI4106)
 PSS007298|
European Ancestry|
10,636 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (L) — — R²: 0.17491 [0.16634, 0.18348]
Incremental R2 (full-covars): 0.11202
PGS R2 (no covariates): 0.11274 [0.10534, 0.12014]		 age, sex, UKB array type, Genotype PCs —
PPM007951 PGS001038
(GBE_INI4106)
 PSS007299|
South Asian Ancestry|
5,043 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (L) — — R²: 0.08123 [0.06963, 0.09282]
Incremental R2 (full-covars): 0.05296
PGS R2 (no covariates): 0.05415 [0.04441, 0.0639]		 age, sex, UKB array type, Genotype PCs —
PPM007952 PGS001038
(GBE_INI4106)
 PSS007300|
European Ancestry|
25,716 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (L) — — R²: 0.17984 [0.17459, 0.18509]
Incremental R2 (full-covars): 0.11708
PGS R2 (no covariates): 0.11589 [0.11134, 0.12043]		 age, sex, UKB array type, Genotype PCs —
PPM007953 PGS001039
(GBE_INI4125)
 PSS007326|
African Ancestry|
3,592 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (R) — — R²: 0.02463 [0.01719, 0.03207]
Incremental R2 (full-covars): 0.00616
PGS R2 (no covariates): 0.00698 [0.00294, 0.01101]		 age, sex, UKB array type, Genotype PCs —
PPM007954 PGS001039
(GBE_INI4125)
 PSS007327|
East Asian Ancestry|
782 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (R) — — R²: 0.09885 [0.072, 0.1257]
Incremental R2 (full-covars): 0.07541
PGS R2 (no covariates): 0.07555 [0.05147, 0.09963]		 age, sex, UKB array type, Genotype PCs —
PPM007955 PGS001039
(GBE_INI4125)
 PSS007328|
European Ancestry|
10,633 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (R) — — R²: 0.1752 [0.16663, 0.18378]
Incremental R2 (full-covars): 0.11145
PGS R2 (no covariates): 0.11271 [0.10531, 0.12011]		 age, sex, UKB array type, Genotype PCs —
PPM007956 PGS001039
(GBE_INI4125)
 PSS007329|
South Asian Ancestry|
5,041 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (R) — — R²: 0.08262 [0.07095, 0.0943]
Incremental R2 (full-covars): 0.05817
PGS R2 (no covariates): 0.05815 [0.0481, 0.06821]		 age, sex, UKB array type, Genotype PCs —
PPM007957 PGS001039
(GBE_INI4125)
 PSS007330|
European Ancestry|
25,728 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (R) — — R²: 0.19359 [0.18823, 0.19894]
Incremental R2 (full-covars): 0.1242
PGS R2 (no covariates): 0.12266 [0.11802, 0.1273]		 age, sex, UKB array type, Genotype PCs —
PPM007080 PGS001402
(GBE_INI3148)
 PSS007241|
African Ancestry|
2,248 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — R²: 0.03461 [0.02588, 0.04334]
Incremental R2 (full-covars): 0.01792
PGS R2 (no covariates): 0.01849 [0.012, 0.02498]		 age, sex, UKB array type, Genotype PCs —
PPM007081 PGS001402
(GBE_INI3148)
 PSS007242|
East Asian Ancestry|
794 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — R²: 0.0956 [0.0691, 0.1221]
Incremental R2 (full-covars): 0.06421
PGS R2 (no covariates): 0.06783 [0.04482, 0.09083]		 age, sex, UKB array type, Genotype PCs —
PPM007082 PGS001402
(GBE_INI3148)
 PSS007243|
European Ancestry|
12,374 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — R²: 0.18897 [0.18022, 0.19773]
Incremental R2 (full-covars): 0.13548
PGS R2 (no covariates): 0.13714 [0.1292, 0.14508]		 age, sex, UKB array type, Genotype PCs —
PPM007083 PGS001402
(GBE_INI3148)
 PSS007244|
South Asian Ancestry|
2,310 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — R²: 0.10415 [0.09135, 0.11695]
Incremental R2 (full-covars): 0.06926
PGS R2 (no covariates): 0.07321 [0.06211, 0.08432]		 age, sex, UKB array type, Genotype PCs —
PPM007084 PGS001402
(GBE_INI3148)
 PSS007245|
European Ancestry|
38,814 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — R²: 0.19926 [0.19386, 0.20465]
Incremental R2 (full-covars): 0.14341
PGS R2 (no covariates): 0.14309 [0.1382, 0.14798]		 age, sex, UKB array type, Genotype PCs —
PPM007100 PGS001403
(GBE_INI4105)
 PSS007291|
African Ancestry|
3,558 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) (L) — — R²: 0.02599 [0.01836, 0.03363]
Incremental R2 (full-covars): 0.00518
PGS R2 (no covariates): 0.00667 [0.00273, 0.01062]		 age, sex, UKB array type, Genotype PCs —
PPM007101 PGS001403
(GBE_INI4105)
 PSS007292|
East Asian Ancestry|
781 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) (L) — — R²: 0.10653 [0.07889, 0.13417]
Incremental R2 (full-covars): 0.08652
PGS R2 (no covariates): 0.08516 [0.05986, 0.11046]		 age, sex, UKB array type, Genotype PCs —
PPM007102 PGS001403
(GBE_INI4105)
 PSS007293|
European Ancestry|
10,626 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) (L) — — R²: 0.17743 [0.16883, 0.18604]
Incremental R2 (full-covars): 0.11194
PGS R2 (no covariates): 0.11269 [0.10529, 0.12009]		 age, sex, UKB array type, Genotype PCs —
PPM007103 PGS001403
(GBE_INI4105)
 PSS007294|
South Asian Ancestry|
5,037 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) (L) — — R²: 0.08239 [0.07073, 0.09405]
Incremental R2 (full-covars): 0.05357
PGS R2 (no covariates): 0.05487 [0.04506, 0.06467]		 age, sex, UKB array type, Genotype PCs —
PPM007104 PGS001403
(GBE_INI4105)
 PSS007295|
European Ancestry|
25,706 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) (L) — — R²: 0.18131 [0.17605, 0.18657]
Incremental R2 (full-covars): 0.11744
PGS R2 (no covariates): 0.11656 [0.11201, 0.12112]		 age, sex, UKB array type, Genotype PCs —
PPM007110 PGS001404
(GBE_INI4124)
 PSS007321|
African Ancestry|
3,586 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) (R) — — R²: 0.02449 [0.01707, 0.03191]
Incremental R2 (full-covars): 0.00554
PGS R2 (no covariates): 0.00662 [0.00269, 0.01055]		 age, sex, UKB array type, Genotype PCs —
PPM007111 PGS001404
(GBE_INI4124)
 PSS007322|
East Asian Ancestry|
782 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) (R) — — R²: 0.09993 [0.07297, 0.12689]
Incremental R2 (full-covars): 0.0765
PGS R2 (no covariates): 0.0766 [0.05238, 0.10082]		 age, sex, UKB array type, Genotype PCs —
PPM007112 PGS001404
(GBE_INI4124)
 PSS007323|
European Ancestry|
10,627 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) (R) — — R²: 0.17605 [0.16746, 0.18463]
Incremental R2 (full-covars): 0.11134
PGS R2 (no covariates): 0.11225 [0.10487, 0.11964]		 age, sex, UKB array type, Genotype PCs —
PPM007113 PGS001404
(GBE_INI4124)
 PSS007324|
South Asian Ancestry|
5,032 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) (R) — — R²: 0.08461 [0.07282, 0.0964]
Incremental R2 (full-covars): 0.05881
PGS R2 (no covariates): 0.05872 [0.04862, 0.06882]		 age, sex, UKB array type, Genotype PCs —
PPM007114 PGS001404
(GBE_INI4124)
 PSS007325|
European Ancestry|
25,715 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) (R) — — R²: 0.196 [0.19063, 0.20138]
Incremental R2 (full-covars): 0.12507
PGS R2 (no covariates): 0.12352 [0.11887, 0.12817]		 age, sex, UKB array type, Genotype PCs —
PPM010515 PGS001955
(portability-PLR_log_heel_BMD)
 PSS009446|
European Ancestry|
11,484 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.4537 [0.4391, 0.4682] sex, age, birth date, deprivation index, 16 PCs —
PPM010516 PGS001955
(portability-PLR_log_heel_BMD)
 PSS009220|
European Ancestry|
2,146 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.4397 [0.4048, 0.4734] sex, age, birth date, deprivation index, 16 PCs —
PPM010519 PGS001955
(portability-PLR_log_heel_BMD)
 PSS008326|
South Asian Ancestry|
1,972 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.3477 [0.3081, 0.3861] sex, age, birth date, deprivation index, 16 PCs —
PPM010520 PGS001955
(portability-PLR_log_heel_BMD)
 PSS008103|
East Asian Ancestry|
820 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.3057 [0.2415, 0.3672] sex, age, birth date, deprivation index, 16 PCs —
PPM010521 PGS001955
(portability-PLR_log_heel_BMD)
 PSS007890|
African Ancestry|
790 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.1895 [0.1204, 0.2567] sex, age, birth date, deprivation index, 16 PCs —
PPM010522 PGS001955
(portability-PLR_log_heel_BMD)
 PSS008994|
African Ancestry|
1,406 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.1746 [0.1231, 0.2252] sex, age, birth date, deprivation index, 16 PCs —
PPM010517 PGS001955
(portability-PLR_log_heel_BMD)
 PSS008774|
European Ancestry|
3,461 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.3929 [0.3643, 0.4208] sex, age, birth date, deprivation index, 16 PCs —
PPM010518 PGS001955
(portability-PLR_log_heel_BMD)
 PSS008548|
Greater Middle Eastern Ancestry|
506 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.2944 [0.211, 0.3736] sex, age, birth date, deprivation index, 16 PCs —
PPM012231 PGS002173
(portability-ldpred2_log_heel_BMD)
 PSS009446|
European Ancestry|
11,484 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.4429 [0.428, 0.4575] sex, age, birth date, deprivation index, 16 PCs —
PPM012232 PGS002173
(portability-ldpred2_log_heel_BMD)
 PSS009220|
European Ancestry|
2,146 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.4242 [0.3886, 0.4584] sex, age, birth date, deprivation index, 16 PCs —
PPM012233 PGS002173
(portability-ldpred2_log_heel_BMD)
 PSS008774|
European Ancestry|
3,461 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.384 [0.3551, 0.4121] sex, age, birth date, deprivation index, 16 PCs —
PPM012234 PGS002173
(portability-ldpred2_log_heel_BMD)
 PSS008548|
Greater Middle Eastern Ancestry|
506 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.3123 [0.2297, 0.3904] sex, age, birth date, deprivation index, 16 PCs —
PPM012235 PGS002173
(portability-ldpred2_log_heel_BMD)
 PSS008326|
South Asian Ancestry|
1,972 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.338 [0.2981, 0.3767] sex, age, birth date, deprivation index, 16 PCs —
PPM012236 PGS002173
(portability-ldpred2_log_heel_BMD)
 PSS008103|
East Asian Ancestry|
820 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.285 [0.22, 0.3474] sex, age, birth date, deprivation index, 16 PCs —
PPM012237 PGS002173
(portability-ldpred2_log_heel_BMD)
 PSS007890|
African Ancestry|
790 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.1699 [0.1005, 0.2377] sex, age, birth date, deprivation index, 16 PCs —
PPM012238 PGS002173
(portability-ldpred2_log_heel_BMD)
 PSS008994|
African Ancestry|
1,406 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Heel bone mineral density (BMD) — — Partial Correlation (partial-r): 0.1647 [0.113, 0.2154] sex, age, birth date, deprivation index, 16 PCs —
PPM014968 PGS002768
(BMD_prscs)
 PSS009939|
European Ancestry|
39,444 individuals
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Reported Trait: Osteoporosis OR: 1.31 [1.25, 1.38] — — age, sex, 10 PCs, technical covariates —
PPM017631 PGS003535
(cont-decay-log_heel_BMD)
 PSS010647|
European Ancestry|
3,384 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Heel bone mineral density (BMD) — — partial-R2: 0.15 sex, age, deprivation index, PC1-16 —
PPM017799 PGS003535
(cont-decay-log_heel_BMD)
 PSS010227|
European Ancestry|
1,383 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Heel bone mineral density (BMD) — — partial-R2: 0.17 sex, age, deprivation index, PC1-16 —
PPM017883 PGS003535
(cont-decay-log_heel_BMD)
 PSS010479|
South Asian Ancestry|
1,965 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Heel bone mineral density (BMD) — — partial-R2: 0.11 sex, age, deprivation index, PC1-16 —
PPM017967 PGS003535
(cont-decay-log_heel_BMD)
 PSS010395|
East Asian Ancestry|
811 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Heel bone mineral density (BMD) — — partial-R2: 0.07 sex, age, deprivation index, PC1-16 —
PPM018051 PGS003535
(cont-decay-log_heel_BMD)
 PSS010311|
African Ancestry|
786 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Heel bone mineral density (BMD) — — partial-R2: 0.02 sex, age, deprivation index, PC1-16 —
PPM018135 PGS003535
(cont-decay-log_heel_BMD)
 PSS010731|
African Ancestry|
1,397 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Heel bone mineral density (BMD) — — partial-R2: 0.03 sex, age, deprivation index, PC1-16 —
PPM017463 PGS003535
(cont-decay-log_heel_BMD)
 PSS010899|
European Ancestry|
11,350 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Heel bone mineral density (BMD) — — partial-R2: 0.2 sex, age, deprivation index, PC1-16 —
PPM017547 PGS003535
(cont-decay-log_heel_BMD)
 PSS010815|
European Ancestry|
2,145 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Heel bone mineral density (BMD) — — partial-R2: 0.19 sex, age, deprivation index, PC1-16 —
PPM017715 PGS003535
(cont-decay-log_heel_BMD)
 PSS010563|
Greater Middle Eastern Ancestry|
487 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Heel bone mineral density (BMD) — — partial-R2: 0.1 sex, age, deprivation index, PC1-16 —
PPM020526 PGS004411
(X78.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated — — PGS R2 (no covariates): 0.30125 — —
PPM020530 PGS004415
(X3148.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel bone mineral density (BMD) — — PGS R2 (no covariates): 0.30248 — —
PPM020534 PGS004419
(X4105.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel bone mineral density (BMD) (left) — — PGS R2 (no covariates): 0.2483 — —
PPM020535 PGS004420
(X4106.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (left) — — PGS R2 (no covariates): 0.24744 — —
PPM020539 PGS004424
(X4124.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel bone mineral density (BMD) (right) — — PGS R2 (no covariates): 0.24863 — —
PPM020540 PGS004425
(X4125.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Heel bone mineral density (BMD) T-score, automated (right) — — PGS R2 (no covariates): 0.24814 — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008774 — — 3,461 individuals — European Italy (South Europe) UKB —
PSS007241 — — 2,248 individuals — African unspecified — UKB —
PSS007242 — — 794 individuals — East Asian — UKB —
PSS007243 — — 12,374 individuals — European non-white British ancestry UKB —
PSS007244 — — 2,310 individuals — South Asian — UKB —
PSS007245 — — 38,814 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS007890 — — 790 individuals — African American or Afro-Caribbean Carribean UKB —
PSS008994 — — 1,406 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008548 — — 506 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS010815 — — 2,145 individuals,
39.0 % Male samples
 Mean = 54.3 years
Sd = 7.2 years		 European Polish UKB —
PSS009446 — — 11,484 individuals — European UK (+ Ireland) UKB —
PSS010563 — — 487 individuals,
65.0 % Male samples
 Mean = 51.1 years
Sd = 7.6 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010311 — — 786 individuals,
35.0 % Male samples
 Mean = 52.2 years
Sd = 8.1 years		 African American or Afro-Caribbean Caribbean UKB —
PSS009939 — — 39,444 individuals — European
(Finnish)		 — FinnGen —
PSS007291 — — 3,558 individuals — African unspecified — UKB —
PSS007292 — — 781 individuals — East Asian — UKB —
PSS007293 — — 10,626 individuals — European non-white British ancestry UKB —
PSS007294 — — 5,037 individuals — South Asian — UKB —
PSS007295 — — 25,706 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS007296 — — 3,560 individuals — African unspecified — UKB —
PSS007297 — — 781 individuals — East Asian — UKB —
PSS007298 — — 10,636 individuals — European non-white British ancestry UKB —
PSS007299 — — 5,043 individuals — South Asian — UKB —
PSS007300 — — 25,716 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS009220 — — 2,146 individuals — European Poland (NE Europe) UKB —
PSS008326 — — 1,972 individuals — South Asian India (South Asia) UKB —
PSS010731 — — 1,397 individuals,
49.0 % Male samples
 Mean = 51.9 years
Sd = 8.1 years		 African unspecified Nigerian UKB —
PSS010479 — — 1,965 individuals,
55.0 % Male samples
 Mean = 52.7 years
Sd = 8.2 years		 South Asian Indian UKB —
PSS010227 — — 1,383 individuals,
46.0 % Male samples
 Mean = 57.7 years
Sd = 7.1 years		 European Ashkenazi UKB —
PSS011364 — — 56,192 individuals — European — UKB —
PSS007321 — — 3,586 individuals — African unspecified — UKB —
PSS007322 — — 782 individuals — East Asian — UKB —
PSS007323 — — 10,627 individuals — European non-white British ancestry UKB —
PSS007324 — — 5,032 individuals — South Asian — UKB —
PSS007325 — — 25,715 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS007326 — — 3,592 individuals — African unspecified — UKB —
PSS007327 — — 782 individuals — East Asian — UKB —
PSS007328 — — 10,633 individuals — European non-white British ancestry UKB —
PSS007329 — — 5,041 individuals — South Asian — UKB —
PSS007330 — — 25,728 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS008103 — — 820 individuals — East Asian China (East Asia) UKB —
PSS010647 — — 3,384 individuals,
46.0 % Male samples
 Mean = 54.5 years
Sd = 8.2 years		 European Italian UKB —
PSS010899 — — 11,350 individuals,
46.0 % Male samples
 Mean = 56.9 years
Sd = 7.8 years		 European white British UKB —
PSS007476 — — 2,253 individuals — African unspecified — UKB —
PSS007477 — — 795 individuals — East Asian — UKB —
PSS007478 — — 12,376 individuals — European non-white British ancestry UKB —
PSS007479 — — 2,312 individuals — South Asian — UKB —
PSS007480 — — 38,834 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS010395 — — 811 individuals,
35.0 % Male samples
 Mean = 51.9 years
Sd = 7.5 years		 East Asian Chinese UKB —