Trait: hippocampus fimbria volume

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009402
Description Volume of hippocampus fimbria volume.
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003675
(L_fimbria_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left fimbria volume hippocampus fimbria volume 25,282
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003675/ScoringFiles/PGS003675.txt.gz
PGS003676
(R_fimbria_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right fimbria volume hippocampus fimbria volume 39,045
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003676/ScoringFiles/PGS003676.txt.gz
PGS003677
(L_fimbria_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left fimbria volume hippocampus fimbria volume 19,944
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003677/ScoringFiles/PGS003677.txt.gz
PGS003678
(R_fimbria_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right fimbria volume hippocampus fimbria volume 70,659
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003678/ScoringFiles/PGS003678.txt.gz
PGS003679
(L_fimbria_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left fimbria volume hippocampus fimbria volume 59,016
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003679/ScoringFiles/PGS003679.txt.gz
PGS003680
(R_fimbria_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right fimbria volume hippocampus fimbria volume 13,970
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003680/ScoringFiles/PGS003680.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM018303 PGS003675
(L_fimbria_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left fimbria volume — — R²: 0.01168 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018324 PGS003676
(R_fimbria_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right fimbria volume — — R²: 0.00509 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018347 PGS003677
(L_fimbria_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left fimbria volume — — R²: 0.0137 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018368 PGS003678
(R_fimbria_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right fimbria volume — — R²: 0.0032 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018391 PGS003679
(L_fimbria_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left fimbria volume — — R²: 0.00564 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018412 PGS003680
(R_fimbria_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right fimbria volume — — R²: 0.00362 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS010958 — — 1,999 individuals — East Asian — CHIMGEN —