Experimental Factor Ontology (EFO) Information | |
Identifier | EFO_0009589 |
Description | Quantification of whether an individual feels or felt worried. | Trait category |
Other measurement
|
Mapped term | PMID:29500382 |
Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
---|---|---|---|---|---|---|
PGS001021 (GBE_BIN1980) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Feelings of worry or anxiety | worry measurement, anxiety measurement |
9,747 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001021/ScoringFiles/PGS001021.txt.gz |
PGS001022 (GBE_BIN2000) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Worry too long after an embarrassing experience | worry measurement | 7,714 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001022/ScoringFiles/PGS001022.txt.gz |
PGS001920 (portability-PLR_foreboding_feelings) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Recent feelings of foreboding | worry measurement | 2,894 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001920/ScoringFiles/PGS001920.txt.gz |
PGS002136 (portability-ldpred2_foreboding_feelings) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Recent feelings of foreboding | worry measurement | 733,839 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002136/ScoringFiles/PGS002136.txt.gz |
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|---|
PPM007868 | PGS001021 (GBE_BIN1980) |
PSS003642| African Ancestry| 6,104 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Worrier / anxious feelings | — | AUROC: 0.60438 [0.59021, 0.61855] | R²: 0.04352 Incremental AUROC (full-covars): -0.00571 PGS R2 (no covariates): 0.00129 PGS AUROC (no covariates): 0.51656 [0.50201, 0.53111] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM007869 | PGS001021 (GBE_BIN1980) |
PSS003643| East Asian Ancestry| 1,544 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Worrier / anxious feelings | — | AUROC: 0.58907 [0.5608, 0.61733] | R²: 0.03544 Incremental AUROC (full-covars): 0.01078 PGS R2 (no covariates): 0.0074 PGS AUROC (no covariates): 0.54082 [0.51208, 0.56956] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM007870 | PGS001021 (GBE_BIN1980) |
PSS003644| European Ancestry| 24,170 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Worrier / anxious feelings | — | AUROC: 0.6078 [0.60064, 0.61496] | R²: 0.04664 Incremental AUROC (full-covars): 0.01418 PGS R2 (no covariates): 0.01254 PGS AUROC (no covariates): 0.55518 [0.54786, 0.56249] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM007871 | PGS001021 (GBE_BIN1980) |
PSS003645| South Asian Ancestry| 7,170 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Worrier / anxious feelings | — | AUROC: 0.59978 [0.58669, 0.61287] | R²: 0.03875 Incremental AUROC (full-covars): -0.00373 PGS R2 (no covariates): 0.00244 PGS AUROC (no covariates): 0.5253 [0.51187, 0.53873] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM007872 | PGS001021 (GBE_BIN1980) |
PSS003646| European Ancestry| 65,798 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Worrier / anxious feelings | — | AUROC: 0.6164 [0.61209, 0.62072] | R²: 0.05295 Incremental AUROC (full-covars): 0.0259 PGS R2 (no covariates): 0.01465 PGS AUROC (no covariates): 0.55972 [0.5553, 0.56414] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM007873 | PGS001022 (GBE_BIN2000) |
PSS003647| African Ancestry| 6,089 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Worry too long after embarrassment | — | AUROC: 0.56572 [0.55125, 0.58019] | R²: 0.01766 Incremental AUROC (full-covars): -0.00878 PGS R2 (no covariates): 0.00047 PGS AUROC (no covariates): 0.50946 [0.49481, 0.52411] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM007874 | PGS001022 (GBE_BIN2000) |
PSS003648| East Asian Ancestry| 1,530 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Worry too long after embarrassment | — | AUROC: 0.56492 [0.5358, 0.59403] | R²: 0.01813 Incremental AUROC (full-covars): -0.0008 PGS R2 (no covariates): 0.00097 PGS AUROC (no covariates): 0.52058 [0.49125, 0.5499] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM007875 | PGS001022 (GBE_BIN2000) |
PSS003649| European Ancestry| 23,849 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Worry too long after embarrassment | — | AUROC: 0.58127 [0.57406, 0.58848] | R²: 0.02677 Incremental AUROC (full-covars): 0.01383 PGS R2 (no covariates): 0.00912 PGS AUROC (no covariates): 0.54606 [0.53877, 0.55335] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM007876 | PGS001022 (GBE_BIN2000) |
PSS003650| South Asian Ancestry| 6,993 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Worry too long after embarrassment | — | AUROC: 0.56486 [0.55147, 0.57825] | R²: 0.01811 Incremental AUROC (full-covars): 0.00478 PGS R2 (no covariates): 0.00488 PGS AUROC (no covariates): 0.53067 [0.51717, 0.54417] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM007877 | PGS001022 (GBE_BIN2000) |
PSS003651| European Ancestry| 64,908 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Worry too long after embarrassment | — | AUROC: 0.59904 [0.5947, 0.60337] | R²: 0.03927 Incremental AUROC (full-covars): 0.01689 PGS R2 (no covariates): 0.01075 PGS AUROC (no covariates): 0.55091 [0.5465, 0.55532] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM010239 | PGS001920 (portability-PLR_foreboding_feelings) |
PSS009407| European Ancestry| 6,430 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.0282 [0.0037, 0.0526] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010240 | PGS001920 (portability-PLR_foreboding_feelings) |
PSS009181| European Ancestry| 1,238 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.0479 [-0.0082, 0.1038] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010241 | PGS001920 (portability-PLR_foreboding_feelings) |
PSS008735| European Ancestry| 2,246 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.0291 [-0.0125, 0.0705] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010242 | PGS001920 (portability-PLR_foreboding_feelings) |
PSS008509| Greater Middle Eastern Ancestry| 198 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): -0.0194 [-0.1661, 0.128] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010243 | PGS001920 (portability-PLR_foreboding_feelings) |
PSS008287| South Asian Ancestry| 807 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.1152 [0.0457, 0.1837] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010244 | PGS001920 (portability-PLR_foreboding_feelings) |
PSS008064| East Asian Ancestry| 421 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): -0.0358 [-0.1333, 0.0623] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010245 | PGS001920 (portability-PLR_foreboding_feelings) |
PSS007851| African Ancestry| 370 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.1352 [0.0308, 0.2367] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010246 | PGS001920 (portability-PLR_foreboding_feelings) |
PSS008955| African Ancestry| 507 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): -0.0521 [-0.1403, 0.0369] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011939 | PGS002136 (portability-ldpred2_foreboding_feelings) |
PSS009407| European Ancestry| 6,430 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.0695 [0.0451, 0.0939] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011940 | PGS002136 (portability-ldpred2_foreboding_feelings) |
PSS009181| European Ancestry| 1,238 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.0131 [-0.0431, 0.0692] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011941 | PGS002136 (portability-ldpred2_foreboding_feelings) |
PSS008735| European Ancestry| 2,246 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.0387 [-0.0029, 0.0801] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011942 | PGS002136 (portability-ldpred2_foreboding_feelings) |
PSS008509| Greater Middle Eastern Ancestry| 198 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.0313 [-0.1163, 0.1776] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011943 | PGS002136 (portability-ldpred2_foreboding_feelings) |
PSS008287| South Asian Ancestry| 807 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.1037 [0.0341, 0.1724] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011944 | PGS002136 (portability-ldpred2_foreboding_feelings) |
PSS008064| East Asian Ancestry| 421 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.0664 [-0.0318, 0.1632] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011945 | PGS002136 (portability-ldpred2_foreboding_feelings) |
PSS007851| African Ancestry| 370 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): 0.1369 [0.0325, 0.2383] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011946 | PGS002136 (portability-ldpred2_foreboding_feelings) |
PSS008955| African Ancestry| 507 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Recent feelings of foreboding | — | — | Partial Correlation (partial-r): -0.0109 [-0.0997, 0.078] | sex, age, birth date, deprivation index, 16 PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS003644 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
PSS003645 | — | — | [
|
— | South Asian | — | UKB | — |
PSS003646 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
PSS003647 | — | — | [
|
— | African unspecified | — | UKB | — |
PSS003648 | — | — | [
|
— | East Asian | — | UKB | — |
PSS003649 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
PSS003650 | — | — | [
|
— | South Asian | — | UKB | — |
PSS003651 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
PSS007851 | — | — | 370 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
PSS008509 | — | — | 198 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
PSS008287 | — | — | 807 individuals | — | South Asian | India (South Asia) | UKB | — |
PSS008955 | — | — | 507 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
PSS009181 | — | — | 1,238 individuals | — | European | Poland (NE Europe) | UKB | — |
PSS008735 | — | — | 2,246 individuals | — | European | Italy (South Europe) | UKB | — |
PSS009407 | — | — | 6,430 individuals | — | European | UK (+ Ireland) | UKB | — |
PSS008064 | — | — | 421 individuals | — | East Asian | China (East Asia) | UKB | — |
PSS003642 | — | — | [
|
— | African unspecified | — | UKB | — |
PSS003643 | — | — | [
|
— | East Asian | — | UKB | — |