Trait: urinary potassium measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0010952
Description A quantitative measurement of the total amount of potassium present in a sample of urine.
Trait category
Other measurement
Synonym urine potassium measurement
Mapped terms 3 mapped terms
  • NCIt:C61047
  • ORCID:0000-0001-8222-008X
  • PMID:33462484

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000693
(snpnet.Potassium_in_urine)
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Potassium in urine [mmol/L] urinary potassium measurement 2,423
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000693/ScoringFiles/PGS000693.txt.gz - Check Terms/Licenses
PGS001974
(portability-PLR_log_potassium_urine)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Potassium in urine urinary potassium measurement 21,512
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001974/ScoringFiles/PGS001974.txt.gz
PGS002192
(portability-ldpred2_log_potassium_urine)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Potassium in urine urinary potassium measurement 881,567
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002192/ScoringFiles/PGS002192.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM001421 PGS000693
(snpnet.Potassium_in_urine)
 PSS000739|
African Ancestry|
5,786 individuals
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Reported Trait: Potassium in urine [mmol/L] — — R²: 0.03001
Spearman's ρ: 0.011		 Age, sex, PCs(1-40) —
PPM001456 PGS000693
(snpnet.Potassium_in_urine)
 PSS000740|
East Asian Ancestry|
1,045 individuals
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Reported Trait: Potassium in urine [mmol/L] — — R²: 0.01859
Spearman's ρ: 0.038		 Age, sex, PCs(1-40) —
PPM001491 PGS000693
(snpnet.Potassium_in_urine)
 PSS000741|
European Ancestry|
22,839 individuals
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Reported Trait: Potassium in urine [mmol/L] — — R²: 0.04847
Spearman's ρ: 0.036		 Age, sex, PCs(1-40) —
PPM001589 PGS000693
(snpnet.Potassium_in_urine)
 PSS000835|
European Ancestry|
2,117 individuals
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Reported Trait: Potassium in urine [mmol/L] — — Spearman's ρ: 0.065 Age, sex —
PPM001526 PGS000693
(snpnet.Potassium_in_urine)
 PSS000742|
South Asian Ancestry|
6,998 individuals
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Reported Trait: Potassium in urine [mmol/L] — — R²: 0.06035
Spearman's ρ: 0.027		 Age, sex, PCs(1-40) —
PPM001561 PGS000693
(snpnet.Potassium_in_urine)
 PSS000743|
European Ancestry|
62,013 individuals
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Reported Trait: Potassium in urine [mmol/L] — — R²: 0.04727
Spearman's ρ: 0.042		 Age, sex, PCs(1-40) —
PPM007390 PGS000693
(snpnet.Potassium_in_urine)
 PSS007056|
African Ancestry|
6,238 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.		 Reported Trait: Potassium in urine — — R²: 0.01656 [0.01041, 0.02271]
Incremental R2 (full-covars): 1e-05
PGS R2 (no covariates): 0.0 [-0.00009, 0.0001]		 age, sex, UKB array type, Genotype PCs —
PPM007391 PGS000693
(snpnet.Potassium_in_urine)
 PSS007057|
East Asian Ancestry|
1,642 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.		 Reported Trait: Potassium in urine — — R²: 0.02067 [0.00733, 0.03401]
Incremental R2 (full-covars): 6e-05
PGS R2 (no covariates): 0.00061 [-0.00173, 0.00295]		 age, sex, UKB array type, Genotype PCs —
PPM007392 PGS000693
(snpnet.Potassium_in_urine)
 PSS007058|
European Ancestry|
24,108 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.		 Reported Trait: Potassium in urine — — R²: 0.02543 [0.02157, 0.02928]
Incremental R2 (full-covars): 6e-05
PGS R2 (no covariates): 0.00097 [0.0002, 0.00175]		 age, sex, UKB array type, Genotype PCs —
PPM007393 PGS000693
(snpnet.Potassium_in_urine)
 PSS007059|
South Asian Ancestry|
7,464 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.		 Reported Trait: Potassium in urine — — R²: 0.03366 [0.02581, 0.04151]
Incremental R2 (full-covars): 6e-05
PGS R2 (no covariates): 0.00101 [-0.00039, 0.00242]		 age, sex, UKB array type, Genotype PCs —
PPM007394 PGS000693
(snpnet.Potassium_in_urine)
 PSS007060|
European Ancestry|
65,536 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
|Ext.		 Reported Trait: Potassium in urine — — R²: 0.02071 [0.01858, 0.02283]
Incremental R2 (full-covars): 7e-05
PGS R2 (no covariates): 0.00149 [0.0009, 0.00207]		 age, sex, UKB array type, Genotype PCs —
PPM010667 PGS001974
(portability-PLR_log_potassium_urine)
 PSS009463|
European Ancestry|
19,363 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0706 [0.0565, 0.0846] sex, age, birth date, deprivation index, 16 PCs —
PPM010668 PGS001974
(portability-PLR_log_potassium_urine)
 PSS009237|
European Ancestry|
3,970 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0851 [0.0541, 0.116] sex, age, birth date, deprivation index, 16 PCs —
PPM010669 PGS001974
(portability-PLR_log_potassium_urine)
 PSS008791|
European Ancestry|
6,432 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0709 [0.0465, 0.0952] sex, age, birth date, deprivation index, 16 PCs —
PPM010671 PGS001974
(portability-PLR_log_potassium_urine)
 PSS008343|
South Asian Ancestry|
6,020 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0626 [0.0373, 0.0877] sex, age, birth date, deprivation index, 16 PCs —
PPM010672 PGS001974
(portability-PLR_log_potassium_urine)
 PSS008120|
East Asian Ancestry|
1,743 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0368 [-0.0104, 0.0839] sex, age, birth date, deprivation index, 16 PCs —
PPM010673 PGS001974
(portability-PLR_log_potassium_urine)
 PSS007907|
African Ancestry|
2,382 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0381 [-0.0022, 0.0783] sex, age, birth date, deprivation index, 16 PCs —
PPM010674 PGS001974
(portability-PLR_log_potassium_urine)
 PSS009011|
African Ancestry|
3,772 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0225 [-0.0095, 0.0545] sex, age, birth date, deprivation index, 16 PCs —
PPM010670 PGS001974
(portability-PLR_log_potassium_urine)
 PSS008565|
Greater Middle Eastern Ancestry|
1,146 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0884 [0.0302, 0.1461] sex, age, birth date, deprivation index, 16 PCs —
PPM012383 PGS002192
(portability-ldpred2_log_potassium_urine)
 PSS009463|
European Ancestry|
19,363 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0895 [0.0755, 0.1035] sex, age, birth date, deprivation index, 16 PCs —
PPM012384 PGS002192
(portability-ldpred2_log_potassium_urine)
 PSS009237|
European Ancestry|
3,970 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0989 [0.068, 0.1297] sex, age, birth date, deprivation index, 16 PCs —
PPM012385 PGS002192
(portability-ldpred2_log_potassium_urine)
 PSS008791|
European Ancestry|
6,432 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0851 [0.0607, 0.1093] sex, age, birth date, deprivation index, 16 PCs —
PPM012387 PGS002192
(portability-ldpred2_log_potassium_urine)
 PSS008343|
South Asian Ancestry|
6,020 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0781 [0.0529, 0.1032] sex, age, birth date, deprivation index, 16 PCs —
PPM012388 PGS002192
(portability-ldpred2_log_potassium_urine)
 PSS008120|
East Asian Ancestry|
1,743 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0486 [0.0014, 0.0956] sex, age, birth date, deprivation index, 16 PCs —
PPM012389 PGS002192
(portability-ldpred2_log_potassium_urine)
 PSS007907|
African Ancestry|
2,382 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0379 [-0.0024, 0.0782] sex, age, birth date, deprivation index, 16 PCs —
PPM012386 PGS002192
(portability-ldpred2_log_potassium_urine)
 PSS008565|
Greater Middle Eastern Ancestry|
1,146 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.1133 [0.0553, 0.1706] sex, age, birth date, deprivation index, 16 PCs —
PPM012390 PGS002192
(portability-ldpred2_log_potassium_urine)
 PSS009011|
African Ancestry|
3,772 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Potassium in urine — — Partial Correlation (partial-r): 0.0304 [-0.0016, 0.0623] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008791 — — 6,432 individuals — European Italy (South Europe) UKB —
PSS000835 — — 2,117 individuals — European Participants self-identifying as white MESA —
PSS007907 — — 2,382 individuals — African American or Afro-Caribbean Carribean UKB —
PSS008565 — — 1,146 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009463 — — 19,363 individuals — European UK (+ Ireland) UKB —
PSS000739 — — 5,786 individuals — African unspecified — UKB —
PSS000740 — — 1,045 individuals — East Asian — UKB —
PSS000741 — — 22,839 individuals — European Non-British White UKB —
PSS000742 — — 6,998 individuals — South Asian — UKB —
PSS000743 — — 62,013 individuals — European
(British)		 — UKB —
PSS009237 — — 3,970 individuals — European Poland (NE Europe) UKB —
PSS008343 — — 6,020 individuals — South Asian India (South Asia) UKB —
PSS007056 — — 6,238 individuals — African unspecified — UKB —
PSS007057 — — 1,642 individuals — East Asian — UKB —
PSS007058 — — 24,108 individuals — European non-white British ancestry UKB —
PSS007059 — — 7,464 individuals — South Asian — UKB —
PSS007060 — — 65,536 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS009011 — — 3,772 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008120 — — 1,743 individuals — East Asian China (East Asia) UKB —