Trait Information | |
Identifier | OBA_1000110 |
Description | The mass density of a bone tissue. [AUTO: patterns/patterns/entity_attribute] | Trait category |
Other measurement
|
Synonyms |
2 synonyms
|
Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
---|---|---|---|---|---|---|
PGS000121 (2018_BMD62_GRS.FN) |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Bone mineral density (BMD) | bone density | 62 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000121/ScoringFiles/PGS000121.txt.gz |
PGS000122 (2018_BMD33_GRS.FN) |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Bone mineral density (BMD) | bone density | 33 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000122/ScoringFiles/PGS000122.txt.gz |
PGS002315 (bmd_HEEL_TSCOREz.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Bone mineral density (BMD) | bone density | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002315/ScoringFiles/PGS002315.txt.gz |
PGS002387 (bmd_HEEL_TSCOREz.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Bone mineral density (BMD) | bone density | 25,831 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002387/ScoringFiles/PGS002387.txt.gz |
PGS002436 (bmd_HEEL_TSCOREz.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Bone mineral density (BMD) | bone density | 53,472 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002436/ScoringFiles/PGS002436.txt.gz |
PGS002485 (bmd_HEEL_TSCOREz.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Bone mineral density (BMD) | bone density | 171,392 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002485/ScoringFiles/PGS002485.txt.gz |
PGS002534 (bmd_HEEL_TSCOREz.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Bone mineral density (BMD) | bone density | 11,440 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002534/ScoringFiles/PGS002534.txt.gz |
PGS002583 (bmd_HEEL_TSCOREz.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Bone mineral density (BMD) | bone density | 7,908 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002583/ScoringFiles/PGS002583.txt.gz |
PGS002632 (bmd_HEEL_TSCOREz.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Bone mineral density (BMD) | bone density | 432,286 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002632/ScoringFiles/PGS002632.txt.gz |
PGS002681 (bmd_HEEL_TSCOREz.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Bone mineral density (BMD) | bone density | 984,276 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002681/ScoringFiles/PGS002681.txt.gz |
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|---|
PPM000368 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000215| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Vertebral fracture | HR: 1.25 [1.02, 1.56] | — | — | Age | — |
PPM000376 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000216| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Wrist fracture | HR: 1.48 [1.07, 2.06] | — | — | Age | — |
PPM000377 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000216| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Wrist fracture | HR: 1.5 [1.08, 2.09] | — | — | Age, sex, prior fracture or fall | — |
PPM000378 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000216| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Wrist fracture | HR: 1.41 [1.01, 1.96] | — | — | Age, sex, prior fracture or fall, femoral neck bone mineral density | — |
PPM000360 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000213| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Hip fracture | HR: 1.21 [0.91, 1.59] | — | — | Age | — |
PPM000352 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000214| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Total fracture | HR: 1.19 [1.03, 1.37] | — | — | Age | — |
PPM000362 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000213| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Hip fracture | HR: 1.03 [0.77, 1.36] | — | — | Age, sex, prior fracture or fall, femoral neck bone mineral density | — |
PPM000354 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000214| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Total fracture | HR: 1.13 [0.98, 1.29] | — | — | Age, sex, prior fracture or fall, femoral neck bone mineral density | — |
PPM000367 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000215| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Vertebral fracture | HR: 1.28 [1.02, 1.59] | — | — | — | — |
PPM000359 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000213| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Hip fracture | HR: 1.23 [0.92, 1.63] | — | — | — | — |
PPM000351 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000214| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Total fracture | HR: 1.2 [1.04, 1.38] | — | — | — | — |
PPM000350 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000212| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Lumbar spine BMD | β: -0.037 (0.007) | — | — | — | — |
PPM000349 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000212| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Femoral neck BMD | β: -0.019 (0.004) | — | — | — | — |
PPM000375 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000216| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Wrist fracture | HR: 1.51 [1.08, 2.1] | — | — | — | — |
PPM000369 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000215| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Vertebral fracture | HR: 1.24 [1.0, 1.54] | — | — | Age, sex, prior fracture or fall | — |
PPM000361 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000213| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Hip fracture | HR: 1.19 [0.91, 1.57] | — | — | Age, sex, prior fracture or fall | — |
PPM000353 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000214| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Total fracture | HR: 1.18 [1.03, 1.36] | — | — | Age, sex, prior fracture or fall | — |
PPM000370 | PGS000121 (2018_BMD62_GRS.FN) |
PSS000215| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Vertebral fracture | HR: 1.14 [0.92, 1.42] | — | — | Age, sex, prior fracture or fall, femoral neck bone mineral density | — |
PPM000372 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000215| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Vertebral fracture | HR: 1.36 [1.04, 1.78] | — | — | Age | — |
PPM000380 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000216| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Wrist fracture | HR: 1.62 [1.08, 2.43] | — | — | Age | — |
PPM000374 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000215| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Vertebral fracture | HR: 1.28 [0.97, 1.68] | — | — | Age, sex, prior fracture or fall, femoral neck bone mineral density | — |
PPM000364 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000213| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Hip fracture | HR: 1.11 [0.78, 1.57] | — | — | Age | — |
PPM000356 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000214| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Total fracture | HR: 1.26 [1.06, 1.5] | — | — | Age | — |
PPM000366 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000213| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Hip fracture | HR: 1.01 [0.65, 1.35] | — | — | Age, sex, prior fracture or fall, femoral neck bone mineral density | — |
PPM000358 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000214| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Total fracture | HR: 1.23 [1.02, 1.46] | — | — | Age, sex, prior fracture or fall, femoral neck bone mineral density | — |
PPM000371 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000215| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Vertebral fracture | HR: 1.39 [1.06, 1.82] | — | — | — | — |
PPM000363 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000213| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Hip fracture | HR: 1.09 [0.77, 1.54] | — | — | — | — |
PPM000355 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000214| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Total fracture | HR: 1.26 [1.06, 1.5] | — | — | — | — |
PPM000379 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000216| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Wrist fracture | HR: 1.65 [1.09, 2.48] | — | — | — | — |
PPM000381 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000216| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Wrist fracture | HR: 1.6 [1.06, 2.4] | — | — | Age, sex, prior fracture or fall | — |
PPM000373 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000215| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Vertebral fracture | HR: 1.35 [1.03, 1.78] | — | — | Age, sex, prior fracture or fall | — |
PPM000365 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000213| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Hip fracture | HR: 1.06 [0.74, 1.51] | — | — | Age, sex, prior fracture or fall | — |
PPM000357 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000214| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Total fracture | HR: 1.24 [1.04, 1.47] | — | — | Age, sex, prior fracture or fall | — |
PPM000382 | PGS000122 (2018_BMD33_GRS.FN) |
PSS000216| European Ancestry| 1,459 individuals |
PGP000056 | Ho-Le TP et al. J Bone Miner Res (2016) |
Reported Trait: Wrist fracture | HR: 1.53 [1.01, 2.31] | — | — | Age, sex, prior fracture or fall, femoral neck bone mineral density | — |
PPM013129 | PGS002315 (bmd_HEEL_TSCOREz.BOLT-LMM) |
PSS009704| East Asian Ancestry| 889 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.087 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013080 | PGS002315 (bmd_HEEL_TSCOREz.BOLT-LMM) |
PSS009703| African Ancestry| 5,639 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0299 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013178 | PGS002315 (bmd_HEEL_TSCOREz.BOLT-LMM) |
PSS009705| European Ancestry| 42,030 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.2324 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013227 | PGS002315 (bmd_HEEL_TSCOREz.BOLT-LMM) |
PSS009706| South Asian Ancestry| 7,588 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.1529 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013368 | PGS002387 (bmd_HEEL_TSCOREz.P+T.0.0001) |
PSS009703| African Ancestry| 5,639 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0014 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013417 | PGS002387 (bmd_HEEL_TSCOREz.P+T.0.0001) |
PSS009704| East Asian Ancestry| 889 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0509 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013515 | PGS002387 (bmd_HEEL_TSCOREz.P+T.0.0001) |
PSS009706| South Asian Ancestry| 7,588 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0961 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013466 | PGS002387 (bmd_HEEL_TSCOREz.P+T.0.0001) |
PSS009705| European Ancestry| 42,030 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.1523 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013564 | PGS002436 (bmd_HEEL_TSCOREz.P+T.0.001) |
PSS009703| African Ancestry| 5,639 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0008 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013613 | PGS002436 (bmd_HEEL_TSCOREz.P+T.0.001) |
PSS009704| East Asian Ancestry| 889 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0318 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013662 | PGS002436 (bmd_HEEL_TSCOREz.P+T.0.001) |
PSS009705| European Ancestry| 42,030 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.1546 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013711 | PGS002436 (bmd_HEEL_TSCOREz.P+T.0.001) |
PSS009706| South Asian Ancestry| 7,588 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0589 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013760 | PGS002485 (bmd_HEEL_TSCOREz.P+T.0.01) |
PSS009703| African Ancestry| 5,639 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013809 | PGS002485 (bmd_HEEL_TSCOREz.P+T.0.01) |
PSS009704| East Asian Ancestry| 889 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.01 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013858 | PGS002485 (bmd_HEEL_TSCOREz.P+T.0.01) |
PSS009705| European Ancestry| 42,030 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.1186 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013907 | PGS002485 (bmd_HEEL_TSCOREz.P+T.0.01) |
PSS009706| South Asian Ancestry| 7,588 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0253 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013956 | PGS002534 (bmd_HEEL_TSCOREz.P+T.1e-06) |
PSS009703| African Ancestry| 5,639 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0195 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014005 | PGS002534 (bmd_HEEL_TSCOREz.P+T.1e-06) |
PSS009704| East Asian Ancestry| 889 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.046 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014054 | PGS002534 (bmd_HEEL_TSCOREz.P+T.1e-06) |
PSS009705| European Ancestry| 42,030 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.1395 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014103 | PGS002534 (bmd_HEEL_TSCOREz.P+T.1e-06) |
PSS009706| South Asian Ancestry| 7,588 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0891 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014152 | PGS002583 (bmd_HEEL_TSCOREz.P+T.5e-08) |
PSS009703| African Ancestry| 5,639 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0203 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014201 | PGS002583 (bmd_HEEL_TSCOREz.P+T.5e-08) |
PSS009704| East Asian Ancestry| 889 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0426 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014250 | PGS002583 (bmd_HEEL_TSCOREz.P+T.5e-08) |
PSS009705| European Ancestry| 42,030 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.1328 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014299 | PGS002583 (bmd_HEEL_TSCOREz.P+T.5e-08) |
PSS009706| South Asian Ancestry| 7,588 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0836 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014348 | PGS002632 (bmd_HEEL_TSCOREz.PolyFun-pred) |
PSS009703| African Ancestry| 5,639 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0416 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See bmd_HEEL_TSCOREz.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
PPM014397 | PGS002632 (bmd_HEEL_TSCOREz.PolyFun-pred) |
PSS009704| East Asian Ancestry| 889 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0991 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See bmd_HEEL_TSCOREz.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
PPM014446 | PGS002632 (bmd_HEEL_TSCOREz.PolyFun-pred) |
PSS009705| European Ancestry| 42,030 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.2504 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See bmd_HEEL_TSCOREz.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
PPM014495 | PGS002632 (bmd_HEEL_TSCOREz.PolyFun-pred) |
PSS009706| South Asian Ancestry| 7,588 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.1707 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See bmd_HEEL_TSCOREz.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
PPM014544 | PGS002681 (bmd_HEEL_TSCOREz.SBayesR) |
PSS009703| African Ancestry| 5,639 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0298 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014593 | PGS002681 (bmd_HEEL_TSCOREz.SBayesR) |
PSS009704| East Asian Ancestry| 889 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.0805 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014642 | PGS002681 (bmd_HEEL_TSCOREz.SBayesR) |
PSS009705| European Ancestry| 42,030 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.228 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014691 | PGS002681 (bmd_HEEL_TSCOREz.SBayesR) |
PSS009706| South Asian Ancestry| 7,588 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Bone Mineral Density | — | — | Incremental R2 (full model vs. covariates alone): 0.1583 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS000212 | — | — | 902 individuals, 0.0 % Male samples |
Mean = 70.1 years Sd = 7.0 years |
European | — | DOES | — |
PSS000212 | — | — | 557 individuals, 100.0 % Male samples |
Mean = 69.5 years Sd = 5.9 years |
European | — | DOES | — |
PSS000213 | — | — | [ ,
0.0 % Male samples |
Mean = 70.1 years Sd = 7.0 years |
European | — | DOES | — |
PSS000213 | — | — | [ ,
100.0 % Male samples |
Mean = 69.5 years Sd = 5.9 years |
European | — | DOES | — |
PSS000214 | — | — | [ ,
0.0 % Male samples |
Mean = 70.1 years Sd = 7.0 years |
European | — | DOES | — |
PSS000214 | — | — | [ ,
100.0 % Male samples |
Mean = 69.5 years Sd = 5.9 years |
European | — | DOES | — |
PSS000215 | — | — | [ ,
0.0 % Male samples |
Mean = 70.1 years Sd = 7.0 years |
European | — | DOES | — |
PSS000215 | — | — | [ ,
100.0 % Male samples |
Mean = 69.5 years Sd = 5.9 years |
European | — | DOES | — |
PSS000216 | — | — | [ ,
0.0 % Male samples |
Mean = 70.1 years Sd = 7.0 years |
European | — | DOES | — |
PSS000216 | — | — | [ ,
100.0 % Male samples |
Mean = 69.5 years Sd = 5.9 years |
European | — | DOES | — |
PSS009703 | — | — | 5,639 individuals | — | African unspecified | — | UKB | — |
PSS009704 | — | — | 889 individuals | — | East Asian | — | UKB | — |
PSS009705 | — | — | 42,030 individuals | — | European | Non-British European | UKB | — |
PSS009706 | — | — | 7,588 individuals | — | South Asian | — | UKB | — |