Trait: physical activity measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0008002
Description quantification of some aspect of physical activity such as frequency or intensity
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001073
(GBE_INI874)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Duration of walks physical activity measurement 1,323
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001073/ScoringFiles/PGS001073.txt.gz
PGS001074
(GBE_BIN_FC30006164)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Types of physical activity in last 4 weeks (other exercises) physical activity measurement 3,846
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001074/ScoringFiles/PGS001074.txt.gz
PGS001075
(GBE_INI924)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Usual walking pace physical activity measurement 7,535
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001075/ScoringFiles/PGS001075.txt.gz
PGS001397
(GBE_INI971)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Frequency of walking for pleasure in last 4 weeks physical activity measurement 1,276
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001397/ScoringFiles/PGS001397.txt.gz
PGS002254
(PRS_reported)
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Physical activity (self-reported) physical activity measurement,
self-reported trait		 1,142,416
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002254/ScoringFiles/PGS002254.txt.gz
PGS002255
(PRS_measured)
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Physical activity (measured) physical activity measurement 1,140,182
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002255/ScoringFiles/PGS002255.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM008123 PGS001073
(GBE_INI874)
 PSS007481|
African Ancestry|
5,343 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Duration of walks — — R²: 0.00426 [0.0011, 0.00741]
Incremental R2 (full-covars): 0.0008
PGS R2 (no covariates): 0.00083 [-0.00057, 0.00222]		 age, sex, UKB array type, Genotype PCs —
PPM008124 PGS001073
(GBE_INI874)
 PSS007482|
East Asian Ancestry|
1,441 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Duration of walks — — R²: 0.01101 [0.00118, 0.02084]
Incremental R2 (full-covars): 0.00099
PGS R2 (no covariates): 0.00149 [-0.00216, 0.00515]		 age, sex, UKB array type, Genotype PCs —
PPM008125 PGS001073
(GBE_INI874)
 PSS007483|
European Ancestry|
22,129 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Duration of walks — — R²: 0.01036 [0.00786, 0.01287]
Incremental R2 (full-covars): 0.00144
PGS R2 (no covariates): 0.00174 [0.0007, 0.00277]		 age, sex, UKB array type, Genotype PCs —
PPM008126 PGS001073
(GBE_INI874)
 PSS007484|
South Asian Ancestry|
6,613 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Duration of walks — — R²: 0.00724 [0.0035, 0.01099]
Incremental R2 (full-covars): 0.00071
PGS R2 (no covariates): 0.00148 [-0.00022, 0.00318]		 age, sex, UKB array type, Genotype PCs —
PPM008127 PGS001073
(GBE_INI874)
 PSS007485|
European Ancestry|
58,299 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Duration of walks — — R²: 0.00463 [0.00361, 0.00565]
Incremental R2 (full-covars): 0.00051
PGS R2 (no covariates): 0.00069 [0.00029, 0.00109]		 age, sex, UKB array type, Genotype PCs —
PPM008128 PGS001074
(GBE_BIN_FC30006164)
 PSS003889|
African Ancestry|
3,437 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Types of physical activity in last 4 weeks (other exercises) — AUROC: 0.58685 [0.56691, 0.60678] R²: 0.02734
Incremental AUROC (full-covars): -0.01455
PGS R2 (no covariates): 0.00052
PGS AUROC (no covariates): 0.51078 [0.49041, 0.53114]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008129 PGS001074
(GBE_BIN_FC30006164)
 PSS003890|
East Asian Ancestry|
925 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Types of physical activity in last 4 weeks (other exercises) — AUROC: 0.53885 [0.4931, 0.58459] R²: 0.01025
Incremental AUROC (full-covars): -0.02118
PGS R2 (no covariates): 0.00013
PGS AUROC (no covariates): 0.49787 [0.45183, 0.54391]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008130 PGS001074
(GBE_BIN_FC30006164)
 PSS003891|
European Ancestry|
14,151 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Types of physical activity in last 4 weeks (other exercises) — AUROC: 0.62614 [0.61244, 0.63984] R²: 0.04034
Incremental AUROC (full-covars): 0.00763
PGS R2 (no covariates): 0.0082
PGS AUROC (no covariates): 0.5561 [0.54163, 0.57057]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008131 PGS001074
(GBE_BIN_FC30006164)
 PSS003892|
South Asian Ancestry|
3,751 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Types of physical activity in last 4 weeks (other exercises) — AUROC: 0.56075 [0.54088, 0.58063] R²: 0.01505
Incremental AUROC (full-covars): -0.00611
PGS R2 (no covariates): 0.00193
PGS AUROC (no covariates): 0.52395 [0.50376, 0.54414]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008132 PGS001074
(GBE_BIN_FC30006164)
 PSS003893|
European Ancestry|
37,995 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Types of physical activity in last 4 weeks (other exercises) — AUROC: 0.59585 [0.58652, 0.60518] R²: 0.0232
Incremental AUROC (full-covars): 0.00711
PGS R2 (no covariates): 0.0069
PGS AUROC (no covariates): 0.55343 [0.54397, 0.56289]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008133 PGS001075
(GBE_INI924)
 PSS007491|
African Ancestry|
6,309 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Usual walking pace — — R²: 0.02106 [0.01415, 0.02796]
Incremental R2 (full-covars): -0.00129
PGS R2 (no covariates): 0.00166 [-0.00032, 0.00363]		 age, sex, UKB array type, Genotype PCs —
PPM008134 PGS001075
(GBE_INI924)
 PSS007492|
East Asian Ancestry|
1,628 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Usual walking pace — — R²: 0.01729 [0.00505, 0.02954]
Incremental R2 (full-covars): -0.00194
PGS R2 (no covariates): 0.00179 [-0.00221, 0.00578]		 age, sex, UKB array type, Genotype PCs —
PPM008135 PGS001075
(GBE_INI924)
 PSS007493|
European Ancestry|
24,676 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Usual walking pace — — R²: 0.04293 [0.038, 0.04785]
Incremental R2 (full-covars): 0.00907
PGS R2 (no covariates): 0.01048 [0.00796, 0.01299]		 age, sex, UKB array type, Genotype PCs —
PPM008136 PGS001075
(GBE_INI924)
 PSS007494|
South Asian Ancestry|
7,430 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Usual walking pace — — Incremental R2 (full-covars): 0.00199
R²: 0.02131 [0.01498, 0.02763]
PGS R2 (no covariates): 0.00337 [0.00081, 0.00594]		 age, sex, UKB array type, Genotype PCs —
PPM008137 PGS001075
(GBE_INI924)
 PSS007495|
European Ancestry|
67,077 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Usual walking pace — — R²: 0.04297 [0.03998, 0.04597]
Incremental R2 (full-covars): 0.01231
PGS R2 (no covariates): 0.01271 [0.01103, 0.01439]		 age, sex, UKB array type, Genotype PCs —
PPM007230 PGS001397
(GBE_INI971)
 PSS007501|
African Ancestry|
3,349 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Freq. of walking for pleasure in last 4 weeks — — R²: 0.04503 [0.03518, 0.05487]
Incremental R2 (full-covars): -0.00108
PGS R2 (no covariates): 0.0 [-0.00004, 0.00004]		 age, sex, UKB array type, Genotype PCs —
PPM007231 PGS001397
(GBE_INI971)
 PSS007502|
East Asian Ancestry|
912 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Freq. of walking for pleasure in last 4 weeks — — R²: 0.0431 [0.02428, 0.06193]
Incremental R2 (full-covars): -0.00157
PGS R2 (no covariates): 0.00024 [-0.00122, 0.00169]		 age, sex, UKB array type, Genotype PCs —
PPM007232 PGS001397
(GBE_INI971)
 PSS007503|
European Ancestry|
17,807 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Freq. of walking for pleasure in last 4 weeks — — R²: 0.02317 [0.01948, 0.02686]
Incremental R2 (full-covars): 0.0015
PGS R2 (no covariates): 0.00162 [0.00062, 0.00261]		 age, sex, UKB array type, Genotype PCs —
PPM007233 PGS001397
(GBE_INI971)
 PSS007504|
South Asian Ancestry|
4,428 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Freq. of walking for pleasure in last 4 weeks — — R²: 0.04215 [0.03345, 0.05086]
Incremental R2 (full-covars): 0.00033
PGS R2 (no covariates): 0.00052 [-0.00049, 0.00153]		 age, sex, UKB array type, Genotype PCs —
PPM007234 PGS001397
(GBE_INI971)
 PSS007505|
European Ancestry|
49,163 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Freq. of walking for pleasure in last 4 weeks — — R²: 0.01064 [0.0091, 0.01218]
Incremental R2 (full-covars): 0.00095
PGS R2 (no covariates): 0.00098 [0.00051, 0.00146]		 age, sex, UKB array type, Genotype PCs —
PPM012823 PGS002254
(PRS_reported)
 PSS009569|
European Ancestry|
11,528 individuals
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Reported Trait: Daily leisure-time physical activity (MET score) β: 0.1717 (0.0323) — ΔR2 (%): 0.25 age, sex, and four genetic principal components —
PPM012824 PGS002254
(PRS_reported)
 PSS009571|
European Ancestry|
4,061 individuals
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Reported Trait: Daily leisure-time physical activity (MET score) β: 0.0355 (0.0113) — ΔR2 (%): 0.24 age, sex, and four genetic principal components —
PPM021392 PGS002254
(PRS_reported)
 PSS011726|
European Ancestry|
47,148 individuals
 PGP000653 |
Tynkkynen NP et al. Eur J Epidemiol (2023)
|Ext.		 Reported Trait: Self-reported leisure time physical activity β: 0.282 [0.211, 0.354] — R²: 0.014 Age, sex, 10 PCs —
PPM021393 PGS002254
(PRS_reported)
 PSS011726|
European Ancestry|
47,148 individuals
 PGP000653 |
Tynkkynen NP et al. Eur J Epidemiol (2023)
|Ext.		 Reported Trait: Waist circumference β: -0.003 [-0.004, -0.002] — R²: 0.137 Age, sex, 10 PCs —
PPM021394 PGS002254
(PRS_reported)
 PSS011726|
European Ancestry|
47,148 individuals
 PGP000653 |
Tynkkynen NP et al. Eur J Epidemiol (2023)
|Ext.		 Reported Trait: Body mass index β: -0.002 [-0.004, -0.001] — R²: 0.026 Age, sex, 10 PCs —
PPM021395 PGS002254
(PRS_reported)
 PSS011726|
European Ancestry|
47,148 individuals
 PGP000653 |
Tynkkynen NP et al. Eur J Epidemiol (2023)
|Ext.		 Reported Trait: HDL cholesterol β: 0.004 [0.002, 0.006] — R²: 0.134 Age, sex, 10 PCs —
PPM021396 PGS002254
(PRS_reported)
 PSS011725|
European Ancestry|
24,960 individuals
 PGP000653 |
Tynkkynen NP et al. Eur J Epidemiol (2023)
|Ext.		 Reported Trait: Stroke HR: 0.94 [0.903, 0.978] — — — —
PPM021397 PGS002254
(PRS_reported)
 PSS011725|
European Ancestry|
24,960 individuals
 PGP000653 |
Tynkkynen NP et al. Eur J Epidemiol (2023)
|Ext.		 Reported Trait: Hypertensive diseases HR: 0.97 [0.951, 0.99] — — — —
PPM021398 PGS002254
(PRS_reported)
 PSS011725|
European Ancestry|
24,960 individuals
 PGP000653 |
Tynkkynen NP et al. Eur J Epidemiol (2023)
|Ext.		 Reported Trait: Type 2 diabetes HR: 0.935 [0.902, 0.97] — — — —
PPM012825 PGS002255
(PRS_measured)
 PSS009569|
European Ancestry|
11,528 individuals
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Reported Trait: Daily leisure-time physical activity (MET score) β: 0.0908 (0.0321) — ΔR2 (%): 0.07 age, sex, and four genetic principal components —
PPM012826 PGS002255
(PRS_measured)
 PSS009571|
European Ancestry|
4,061 individuals
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Reported Trait: Daily leisure-time physical activity (MET score) β: 0.0405 (0.0112) — ΔR2 (%): 0.32 age, sex, and four genetic principal components —
PPM012827 PGS002255
(PRS_measured)
 PSS009570|
European Ancestry|
765 individuals
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Reported Trait: Daily moderate-to-vigorous physical activity β: 2.497 (1.093) — ΔR2 (%): 0.9 age, sex, and four genetic principal components —
PPM012828 PGS002255
(PRS_measured)
 PSS009571|
European Ancestry|
4,061 individuals
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Reported Trait: Daily moderate-to-vigorous physical activity β: 0.162 (0.0335) — ΔR2 (%): 0.62 age, sex, and four genetic principal components —
PPM012829 PGS002255
(PRS_measured)
 PSS009570|
European Ancestry|
765 individuals
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Reported Trait: Daily steps β: 369.8 (123.3) — ΔR2 (%): 1.44 age, sex, and four genetic principal components —
PPM012830 PGS002255
(PRS_measured)
 PSS009571|
European Ancestry|
4,061 individuals
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Reported Trait: Daily steps β: 365.82 (64.04) — ΔR2 (%): 0.96 age, sex, and four genetic principal components —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007484 — — 6,613 individuals — South Asian — UKB —
PSS007485 — — 58,299 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS007491 — — 6,309 individuals — African unspecified — UKB —
PSS007492 — — 1,628 individuals — East Asian — UKB —
PSS007493 — — 24,676 individuals — European non-white British ancestry UKB —
PSS007494 — — 7,430 individuals — South Asian — UKB —
PSS007495 — — 67,077 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS007501 — — 3,349 individuals — African unspecified — UKB —
PSS007502 — — 912 individuals — East Asian — UKB —
PSS007503 — — 17,807 individuals — European non-white British ancestry UKB —
PSS007504 — — 4,428 individuals — South Asian — UKB —
PSS007505 — — 49,163 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS011725 — — 24,960 individuals,
46.5 % Male samples
 Mean = 59.1 years
Sd = 14.6 years		 European — HUNT —
PSS011726 — — 47,148 individuals,
45.9 % Male samples
 Mean = 52.9 years
Sd = 15.8 years		 European — HUNT —
PSS009569 — — 11,528 individuals,
46.0 % Male samples
 Mean = 44.0 years European
(Finnish)		 — FTC —
PSS009570 — — 765 individuals,
46.0 % Male samples
 Mean = 73.0 years European
(Finnish)		 — NR MOBILETWIN Study
PSS009571 — — 4,061 individuals,
48.0 % Male samples
 Mean = 46.0 years European
(Finnish)		 — NFBC —
PSS003889 — —
[
  • 2,279 cases
  • , 1,158 controls
]
 — African unspecified — UKB —
PSS003890 — —
[
  • 728 cases
  • , 197 controls
]
 — East Asian — UKB —
PSS003891 — —
[
  • 12,417 cases
  • , 1,734 controls
]
 — European non-white British ancestry UKB —
PSS003892 — —
[
  • 2,623 cases
  • , 1,128 controls
]
 — South Asian — UKB —
PSS003893 — —
[
  • 34,031 cases
  • , 3,964 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS007481 — — 5,343 individuals — African unspecified — UKB —
PSS007482 — — 1,441 individuals — East Asian — UKB —
PSS007483 — — 22,129 individuals — European non-white British ancestry UKB —