Trait: sitting height measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0011011
Description Quantification of some aspect of height, when assuming a sitting position.
Trait category
Other measurement
Mapped term PMID:33623009

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000969
(GBE_INI20015)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Sitting height sitting height measurement 36,345
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000969/ScoringFiles/PGS000969.txt.gz
PGS002005
(portability-PLR_sitting_height)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Sitting height sitting height measurement 118,423
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002005/ScoringFiles/PGS002005.txt.gz
PGS002224
(portability-ldpred2_sitting_height)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Sitting height sitting height measurement 910,252
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002224/ScoringFiles/PGS002224.txt.gz
PGS003569
(cont-decay-sitting_height)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Sitting height sitting height measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003569/ScoringFiles/PGS003569.txt.gz
PGS003896
(INI20015)
 PGP000502 |
Tanigawa Y et al. AJHG (2023)
 Sitting height sitting height measurement 44,543
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003896/ScoringFiles/PGS003896.txt.gz
PGS004408
(X20015.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Sitting height sitting height measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004408/ScoringFiles/PGS004408.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007665 PGS000969
(GBE_INI20015)
 PSS004888|
European Ancestry|
24,825 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Sitting height — — R²: 0.55998 [0.5518, 0.56815]
Incremental R2 (full-covars): 0.12693
PGS R2 (no covariates): 0.13335 [0.12549, 0.14121]		 age, sex, UKB array type, Genotype PCs —
PPM007666 PGS000969
(GBE_INI20015)
 PSS004889|
South Asian Ancestry|
7,645 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Sitting height — — R²: 0.52117 [0.50586, 0.53647]
Incremental R2 (full-covars): 0.06153
PGS R2 (no covariates): 0.07384 [0.0627, 0.08499]		 age, sex, UKB array type, Genotype PCs —
PPM007667 PGS000969
(GBE_INI20015)
 PSS004890|
European Ancestry|
67,301 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Sitting height — — R²: 0.56224 [0.55729, 0.5672]
Incremental R2 (full-covars): 0.12957
PGS R2 (no covariates): 0.1276 [0.1229, 0.1323]		 age, sex, UKB array type, Genotype PCs —
PPM007663 PGS000969
(GBE_INI20015)
 PSS004886|
African Ancestry|
6,403 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Sitting height — — R²: 0.3682 [0.34957, 0.38684]
Incremental R2 (full-covars): 0.01039
PGS R2 (no covariates): 0.02603 [0.01839, 0.03367]		 age, sex, UKB array type, Genotype PCs —
PPM007664 PGS000969
(GBE_INI20015)
 PSS004887|
East Asian Ancestry|
1,698 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Sitting height — — R²: 0.49052 [0.45671, 0.52434]
Incremental R2 (full-covars): 0.04748
PGS R2 (no covariates): 0.07798 [0.05358, 0.10237]		 age, sex, UKB array type, Genotype PCs —
PPM010914 PGS002005
(portability-PLR_sitting_height)
 PSS009490|
European Ancestry|
19,908 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.5055 [0.4951, 0.5158] sex, age, birth date, deprivation index, 16 PCs —
PPM010915 PGS002005
(portability-PLR_sitting_height)
 PSS009264|
European Ancestry|
4,122 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.487 [0.4633, 0.51] sex, age, birth date, deprivation index, 16 PCs —
PPM010916 PGS002005
(portability-PLR_sitting_height)
 PSS008818|
European Ancestry|
6,623 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.4655 [0.4464, 0.4842] sex, age, birth date, deprivation index, 16 PCs —
PPM010917 PGS002005
(portability-PLR_sitting_height)
 PSS008592|
Greater Middle Eastern Ancestry|
1,175 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.4025 [0.353, 0.4497] sex, age, birth date, deprivation index, 16 PCs —
PPM010918 PGS002005
(portability-PLR_sitting_height)
 PSS008370|
South Asian Ancestry|
6,123 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.3897 [0.3682, 0.4108] sex, age, birth date, deprivation index, 16 PCs —
PPM010919 PGS002005
(portability-PLR_sitting_height)
 PSS008146|
East Asian Ancestry|
1,800 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.3397 [0.298, 0.3802] sex, age, birth date, deprivation index, 16 PCs —
PPM010920 PGS002005
(portability-PLR_sitting_height)
 PSS007934|
African Ancestry|
2,443 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.24 [0.2021, 0.2772] sex, age, birth date, deprivation index, 16 PCs —
PPM010921 PGS002005
(portability-PLR_sitting_height)
 PSS009038|
African Ancestry|
3,857 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.2113 [0.1808, 0.2413] sex, age, birth date, deprivation index, 16 PCs —
PPM012641 PGS002224
(portability-ldpred2_sitting_height)
 PSS008592|
Greater Middle Eastern Ancestry|
1,175 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.3911 [0.3411, 0.4389] sex, age, birth date, deprivation index, 16 PCs —
PPM012638 PGS002224
(portability-ldpred2_sitting_height)
 PSS009490|
European Ancestry|
19,908 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.4963 [0.4858, 0.5067] sex, age, birth date, deprivation index, 16 PCs —
PPM012639 PGS002224
(portability-ldpred2_sitting_height)
 PSS009264|
European Ancestry|
4,122 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.4829 [0.4591, 0.506] sex, age, birth date, deprivation index, 16 PCs —
PPM012640 PGS002224
(portability-ldpred2_sitting_height)
 PSS008818|
European Ancestry|
6,623 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.4602 [0.441, 0.479] sex, age, birth date, deprivation index, 16 PCs —
PPM012642 PGS002224
(portability-ldpred2_sitting_height)
 PSS008370|
South Asian Ancestry|
6,123 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.3797 [0.358, 0.4009] sex, age, birth date, deprivation index, 16 PCs —
PPM012643 PGS002224
(portability-ldpred2_sitting_height)
 PSS008146|
East Asian Ancestry|
1,800 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.3372 [0.2954, 0.3778] sex, age, birth date, deprivation index, 16 PCs —
PPM012645 PGS002224
(portability-ldpred2_sitting_height)
 PSS009038|
African Ancestry|
3,857 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.1914 [0.1607, 0.2217] sex, age, birth date, deprivation index, 16 PCs —
PPM012644 PGS002224
(portability-ldpred2_sitting_height)
 PSS007934|
African Ancestry|
2,443 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Sitting height — — Partial Correlation (partial-r): 0.2361 [0.1982, 0.2734] sex, age, birth date, deprivation index, 16 PCs —
PPM017497 PGS003569
(cont-decay-sitting_height)
 PSS010937|
European Ancestry|
19,923 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sitting height — — partial-R2: 0.25 sex, age, deprivation index, PC1-16 —
PPM017581 PGS003569
(cont-decay-sitting_height)
 PSS010853|
European Ancestry|
4,111 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sitting height — — partial-R2: 0.23 sex, age, deprivation index, PC1-16 —
PPM017665 PGS003569
(cont-decay-sitting_height)
 PSS010685|
European Ancestry|
6,461 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sitting height — — partial-R2: 0.22 sex, age, deprivation index, PC1-16 —
PPM017833 PGS003569
(cont-decay-sitting_height)
 PSS010265|
European Ancestry|
2,335 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sitting height — — partial-R2: 0.21 sex, age, deprivation index, PC1-16 —
PPM018085 PGS003569
(cont-decay-sitting_height)
 PSS010349|
African Ancestry|
2,430 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sitting height — — partial-R2: 0.06 sex, age, deprivation index, PC1-16 —
PPM018169 PGS003569
(cont-decay-sitting_height)
 PSS010769|
African Ancestry|
3,828 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sitting height — — partial-R2: 0.03 sex, age, deprivation index, PC1-16 —
PPM017749 PGS003569
(cont-decay-sitting_height)
 PSS010601|
Greater Middle Eastern Ancestry|
1,148 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sitting height — — partial-R2: 0.15 sex, age, deprivation index, PC1-16 —
PPM017917 PGS003569
(cont-decay-sitting_height)
 PSS010517|
South Asian Ancestry|
6,072 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sitting height — — partial-R2: 0.15 sex, age, deprivation index, PC1-16 —
PPM018001 PGS003569
(cont-decay-sitting_height)
 PSS010433|
East Asian Ancestry|
1,788 individuals
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Reported Trait: Sitting height — — partial-R2: 0.11 sex, age, deprivation index, PC1-16 —
PPM018799 PGS003896
(INI20015)
 PSS011147|
European Ancestry|
67,606 individuals
 PGP000502 |
Tanigawa Y et al. AJHG (2023)
 Reported Trait: Sitting height — — R²: 0.56702 [0.56211, 0.57193]
PGS R2 (no covariates): 0.13337 [0.12861, 0.13814]
Incremental R2 (full-covars): 0.13166		 age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) —
PPM018800 PGS003896
(INI20015)
 PSS011102|
European Ancestry|
2,883 individuals
 PGP000502 |
Tanigawa Y et al. AJHG (2023)
 Reported Trait: Sitting height — — R²: 0.56319 [0.53933, 0.58705]
PGS R2 (no covariates): 0.14822 [0.12435, 0.17208]
Incremental R2 (full-covars): 0.12786		 age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) —
PPM018801 PGS003896
(INI20015)
 PSS011114|
South Asian Ancestry|
1,448 individuals
 PGP000502 |
Tanigawa Y et al. AJHG (2023)
 Reported Trait: Sitting height — — R²: 0.47658 [0.43993, 0.51322]
PGS R2 (no covariates): 0.06813 [0.04346, 0.09279]
Incremental R2 (full-covars): 0.05017		 age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) —
PPM018802 PGS003896
(INI20015)
 PSS011159|
African Ancestry|
1,191 individuals
 PGP000502 |
Tanigawa Y et al. AJHG (2023)
 Reported Trait: Sitting height — — R²: 0.36181 [0.31873, 0.40489]
PGS R2 (no covariates): 0.01877 [0.00368, 0.03386]
Incremental R2 (full-covars): 0.00631		 age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) —
PPM018803 PGS003896
(INI20015)
 PSS011172|
Multi-ancestry (excluding European)|
7,967 individuals
 PGP000502 |
Tanigawa Y et al. AJHG (2023)
 Reported Trait: Sitting height — — R²: 0.56286 [0.5485, 0.57722]
PGS R2 (no covariates): 0.1462 [0.1319, 0.16049]
Incremental R2 (full-covars): 0.10616		 age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18) —
PPM020523 PGS004408
(X20015.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Sitting height — — PGS R2 (no covariates): 0.28011 — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011147 — — 67,606 individuals — European
(white British ancestry)		 — UKB —
PSS009038 — — 3,857 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008146 — — 1,800 individuals — East Asian China (East Asia) UKB —
PSS011159 — — 1,191 individuals — African unspecified — UKB —
PSS010937 — — 19,923 individuals,
46.0 % Male samples
 Mean = 56.9 years
Sd = 7.9 years		 European white British UKB —
PSS010685 — — 6,461 individuals,
45.0 % Male samples
 Mean = 54.5 years
Sd = 8.4 years		 European Italian UKB —
PSS011172 — — 7,967 individuals — East Asian, Other admixed ancestry East Asian, Other admixed ancestry UKB —
PSS010433 — — 1,788 individuals,
33.0 % Male samples
 Mean = 52.4 years
Sd = 7.8 years		 East Asian Chinese UKB —
PSS008818 — — 6,623 individuals — European Italy (South Europe) UKB —
PSS007934 — — 2,443 individuals — African American or Afro-Caribbean Carribean UKB —
PSS010853 — — 4,111 individuals,
38.0 % Male samples
 Mean = 54.3 years
Sd = 7.5 years		 European Polish UKB —
PSS010601 — — 1,148 individuals,
60.0 % Male samples
 Mean = 52.0 years
Sd = 8.0 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS008592 — — 1,175 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009490 — — 19,908 individuals — European UK (+ Ireland) UKB —
PSS010349 — — 2,430 individuals,
36.0 % Male samples
 Mean = 52.5 years
Sd = 8.1 years		 African American or Afro-Caribbean Caribbean UKB —
PSS004886 — — 6,403 individuals — African unspecified — UKB —
PSS004887 — — 1,698 individuals — East Asian — UKB —
PSS004888 — — 24,825 individuals — European non-white British ancestry UKB —
PSS004889 — — 7,645 individuals — South Asian — UKB —
PSS004890 — — 67,301 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS011102 — — 2,883 individuals — European
(non-white British ancestry)		 — UKB —
PSS011364 — — 56,192 individuals — European — UKB —
PSS011114 — — 1,448 individuals — South Asian — UKB —
PSS009264 — — 4,122 individuals — European Poland (NE Europe) UKB —
PSS008370 — — 6,123 individuals — South Asian India (South Asia) UKB —
PSS010769 — — 3,828 individuals,
46.0 % Male samples
 Mean = 51.9 years
Sd = 8.1 years		 African unspecified Nigerian UKB —
PSS010517 — — 6,072 individuals,
54.0 % Male samples
 Mean = 53.3 years
Sd = 8.4 years		 South Asian Indian UKB —
PSS010265 — — 2,335 individuals,
45.0 % Male samples
 Mean = 58.1 years
Sd = 7.1 years		 European Ashkenazi UKB —