Trait: bipolar disorder

Trait Information
Identifier MONDO_0004985
Description A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression. [NCIT: C34423]
Trait category
Neurological disorder
Synonyms 17 synonyms
  • MAFD
  • bipolar affective disorder
  • bipolar depression
  • bipolar disorder
  • bipolar disorder manic phase
  • depressive-manic psych.
  • major affective disorder
  • major bipolar affective disorder
  • manic bipolar I disorder
  • manic bipolar affective disorder
  • manic depression
  • manic depressive disorder
  • manic disorder
  • manic-depression
  • manic-depressive illness
  • manic-depressive psychosis
  • mixed bipolar disorder
Mapped terms 13 mapped terms
  • DOID:3312
  • ICD10CM:F31
  • ICD10WHO:F31
  • ICD9:296.40
  • ICD9:296.60
  • ICD9:296.80
  • ICD9:296.89
  • MEDGEN:2649
  • MESH:D001714
  • NCIT:C34423
  • NIFSTD:birnlex_12754
  • SCTID:13746004
  • UMLS:C0005586
Child trait(s) 2 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "bipolar disorder" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002786
(BD_SDPR)
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Bipolar disorder bipolar disorder 948,996
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002786/ScoringFiles/PGS002786.txt.gz
PGS002787
(BD1_SDPR)
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Type 1 bipolar disorder bipolar I disorder 937,511
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002787/ScoringFiles/PGS002787.txt.gz
PGS002788
(BD2_SDPR)
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Type 2 bipolar disorder bipolar II disorder 935,292
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002788/ScoringFiles/PGS002788.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM015111 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (reading) — — partial R²: 0.00032 age, PCs1-3 —
PPM015112 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 6e-05 age, PCs1-3 —
PPM015408 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Posterior corona radiata R — — partial R²: 0.00088 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015054 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (anxious/depressed) — — partial R²: 1e-05 age, PCs1-3 —
PPM015055 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (withdrawn) — — partial R²: 5e-05 age, PCs1-3 —
PPM015056 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (somatic symptoms) — — partial R²: 0.00037 age, PCs1-3 —
PPM015057 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (social problems) — — partial R²: 0.00045 age, PCs1-3 —
PPM015058 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (thought problems) — — partial R²: 1.31e-06 age, PCs1-3 —
PPM015059 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (attention problems) — — partial R²: 4e-05 age, PCs1-3 —
PPM015060 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (rule breaking) — — partial R²: 0.00029 age, PCs1-3 —
PPM015061 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (aggressive behaviour) — — partial R²: 9e-05 age, PCs1-3 —
PPM015062 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (internalising) — — partial R²: 4e-05 age, PCs1-3 —
PPM015063 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (externalising) — — partial R²: 0.00015 age, PCs1-3 —
PPM015064 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (total problems) — — partial R²: 4e-05 age, PCs1-3 —
PPM015065 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 depression) — — partial R²: 0.00012 age, PCs1-3 —
PPM015066 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 anxety disorder) — — partial R²: 2e-05 age, PCs1-3 —
PPM015067 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 somatic problem) — — partial R²: 0.00028 age, PCs1-3 —
PPM015068 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 adhd) — — partial R²: 4e-05 age, PCs1-3 —
PPM015070 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 conduct) — — partial R²: 4e-05 age, PCs1-3 —
PPM015071 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Sluggish cognitive tempo) — — partial R²: 0.00037 age, PCs1-3 —
PPM015072 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Obsessive compulsive disorder) — — partial R²: 0.0005 age, PCs1-3 —
PPM015073 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (stress) — — partial R²: 3e-05 age, PCs1-3 —
PPM015074 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture vocabulary) — — partial R²: 0.00014 age, PCs1-3 —
PPM015075 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Flanker test) — — partial R²: 7e-05 age, PCs1-3 —
PPM015076 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (list sorting) — — partial R²: 0.00061 age, PCs1-3 —
PPM015077 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (card sorting) — — partial R²: 0.00037 age, PCs1-3 —
PPM015078 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (pattern comparison) — — partial R²: 0.00251 age, PCs1-3 —
PPM015079 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture sequence) — — partial R²: 0.00023 age, PCs1-3 —
PPM015080 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (reading) — — partial R²: 4e-05 age, PCs1-3 —
PPM015082 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Crystallized composite) — — partial R²: 7.85e-06 age, PCs1-3 —
PPM015083 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Cognitive total) — — partial R²: 0.00087 age, PCs1-3 —
PPM015084 PGS002786
(BD_SDPR)
 PSS009953|
European Ancestry|
68,614 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 7e-05 age, PCs1-10 the observed partial R² were higher than random R²s
PPM015085 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (anxious/depressed) — — partial R²: 0.00119 age, PCs1-3 —
PPM015086 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (withdrawn) — — partial R²: 0.00051 age, PCs1-3 —
PPM015087 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (somatic symptoms) — — partial R²: 0.00027 age, PCs1-3 —
PPM015088 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (social problems) — — partial R²: 0.00079 age, PCs1-3 —
PPM015089 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (thought problems) — — partial R²: 0.0005 age, PCs1-3 —
PPM015090 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (attention problems) — — partial R²: 7e-05 age, PCs1-3 —
PPM015091 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (rule breaking) — — partial R²: 0.00077 age, PCs1-3 —
PPM015093 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (internalising) — — partial R²: 0.00101 age, PCs1-3 —
PPM015094 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (externalising) — — partial R²: 0.00034 age, PCs1-3 —
PPM015095 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (total problems) — — partial R²: 0.00092 age, PCs1-3 —
PPM015096 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 depression) — — partial R²: 0.00196 age, PCs1-3 —
PPM015097 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 anxety disorder) — — partial R²: 0.00198 age, PCs1-3 —
PPM015098 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 somatic problem) — — partial R²: 1.76e-06 age, PCs1-3 —
PPM015099 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 adhd) — — partial R²: 7.78e-07 age, PCs1-3 —
PPM015100 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 opppsit) — — partial R²: 0.00022 age, PCs1-3 —
PPM015101 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 conduct) — — partial R²: 0.00032 age, PCs1-3 —
PPM015102 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Sluggish cognitive tempo) — — partial R²: 0.00067 age, PCs1-3 —
PPM015104 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (stress) — — partial R²: 0.00101 age, PCs1-3 —
PPM015105 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture vocabulary) — — partial R²: 0.00186 age, PCs1-3 —
PPM015106 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Flanker test) — — partial R²: 8.61e-07 age, PCs1-3 —
PPM015107 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (list sorting) — — partial R²: 2e-05 age, PCs1-3 —
PPM015108 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (card sorting) — — partial R²: 6e-05 age, PCs1-3 —
PPM015109 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (pattern comparison) — — partial R²: 3e-05 age, PCs1-3 —
PPM015113 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Crystallized composite) — — partial R²: 0.00135 age, PCs1-3 —
PPM015114 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Cognitive total) — — partial R²: 0.00016 age, PCs1-3 —
PPM015409 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cingulum (cingulate gyrus) R — — partial R²: 0.00095 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015410 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Splenium of corpus callosum — — partial R²: 0.00099 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015411 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Sagittal stratum — — partial R²: 0.00095 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015412 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Uncinate fasciculus L — — partial R²: 0.0009 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015413 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Forceps major — — partial R²: 0.00092 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015415 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Inferior longitudinal fasciculus L — — partial R²: 0.00108 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015416 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Inferior longitudinal fasciculus R — — partial R²: 0.00128 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015417 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Uncinate fasciculus L — — partial R²: 0.00104 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015418 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Uncinate fasciculus R — — partial R²: 0.00089 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015419 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: ICA component_83 — — partial R²: 0.00095 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015420 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: ICA component_137 — — partial R²: 0.00119 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015421 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: ICA component_176 — — partial R²: 0.00116 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015069 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 opppsit) — — partial R²: 5e-05 age, PCs1-3 —
PPM015081 PGS002786
(BD_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 0.00163 age, PCs1-3 —
PPM015092 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (aggressive behaviour) — — partial R²: 0.00017 age, PCs1-3 —
PPM015103 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Obsessive compulsive disorder) — — partial R²: 0.0005 age, PCs1-3 —
PPM015110 PGS002786
(BD_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture sequence) — — partial R²: 0.00037 age, PCs1-3 —
PPM015115 PGS002786
(BD_SDPR)
 PSS009951|
European Ancestry|
78,561 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 7e-05 age, PCs1-10 the observed partial R² were higher than random R²s
PPM015414 PGS002786
(BD_SDPR)
 PSS009952|
European Ancestry|
10,343 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Inferior fronto-occipital fasciculus R — — partial R²: 0.00105 age, headsize scaling factor, PCs1-10 the observed partial R² were higher than random R²s
PPM015116 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (anxious/depressed) — — partial R²: 3.60e-06 age, PCs1-3 —
PPM015117 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (withdrawn) — — partial R²: 9e-05 age, PCs1-3 —
PPM015118 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (somatic symptoms) — — partial R²: 8e-05 age, PCs1-3 —
PPM015119 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (social problems) — — partial R²: 0.00025 age, PCs1-3 —
PPM015120 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (thought problems) — — partial R²: 5e-05 age, PCs1-3 —
PPM015121 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (attention problems) — — partial R²: 3e-05 age, PCs1-3 —
PPM015122 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (rule breaking) — — partial R²: 0.00015 age, PCs1-3 —
PPM015123 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (aggressive behaviour) — — partial R²: 1e-05 age, PCs1-3 —
PPM015124 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (internalising) — — partial R²: 7.64e-07 age, PCs1-3 —
PPM015125 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (externalising) — — partial R²: 4e-05 age, PCs1-3 —
PPM015126 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (total problems) — — partial R²: 1.57e-09 age, PCs1-3 —
PPM015127 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 depression) — — partial R²: 0.00019 age, PCs1-3 —
PPM015128 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 anxety disorder) — — partial R²: 3.52e-06 age, PCs1-3 —
PPM015129 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 somatic problem) — — partial R²: 0.00014 age, PCs1-3 —
PPM015130 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 adhd) — — partial R²: 2.44e-06 age, PCs1-3 —
PPM015132 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 conduct) — — partial R²: 3.41e-06 age, PCs1-3 —
PPM015133 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Sluggish cognitive tempo) — — partial R²: 3e-05 age, PCs1-3 —
PPM015134 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Obsessive compulsive disorder) — — partial R²: 0.00031 age, PCs1-3 —
PPM015135 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (stress) — — partial R²: 2e-05 age, PCs1-3 —
PPM015136 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture vocabulary) — — partial R²: 3e-05 age, PCs1-3 —
PPM015137 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Flanker test) — — partial R²: 9e-05 age, PCs1-3 —
PPM015138 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (list sorting) — — partial R²: 0.00046 age, PCs1-3 —
PPM015139 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (card sorting) — — partial R²: 0.00067 age, PCs1-3 —
PPM015140 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (pattern comparison) — — partial R²: 0.00164 age, PCs1-3 —
PPM015141 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture sequence) — — partial R²: 0.00045 age, PCs1-3 —
PPM015142 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (reading) — — partial R²: 2e-05 age, PCs1-3 —
PPM015144 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Crystallized composite) — — partial R²: 5e-05 age, PCs1-3 —
PPM015145 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Cognitive total) — — partial R²: 0.00115 age, PCs1-3 —
PPM015146 PGS002787
(BD1_SDPR)
 PSS009953|
European Ancestry|
68,614 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 0.00013 age, PCs1-10 the observed partial R² were higher than random R²s
PPM015147 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (anxious/depressed) — — partial R²: 0.00068 age, PCs1-3 —
PPM015148 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (withdrawn) — — partial R²: 7.61e-07 age, PCs1-3 —
PPM015149 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (somatic symptoms) — — partial R²: 0.00059 age, PCs1-3 —
PPM015150 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (social problems) — — partial R²: 0.00013 age, PCs1-3 —
PPM015151 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (thought problems) — — partial R²: 0.00051 age, PCs1-3 —
PPM015152 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (attention problems) — — partial R²: 2e-05 age, PCs1-3 —
PPM015153 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (rule breaking) — — partial R²: 0.00053 age, PCs1-3 —
PPM015155 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (internalising) — — partial R²: 0.00055 age, PCs1-3 —
PPM015156 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (externalising) — — partial R²: 0.00037 age, PCs1-3 —
PPM015157 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (total problems) — — partial R²: 0.00066 age, PCs1-3 —
PPM015158 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 depression) — — partial R²: 0.00275 age, PCs1-3 —
PPM015159 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 anxety disorder) — — partial R²: 0.00081 age, PCs1-3 —
PPM015160 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 somatic problem) — — partial R²: 0.00012 age, PCs1-3 —
PPM015161 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 adhd) — — partial R²: 1.13e-06 age, PCs1-3 —
PPM015162 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 opppsit) — — partial R²: 0.00032 age, PCs1-3 —
PPM015163 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 conduct) — — partial R²: 0.00024 age, PCs1-3 —
PPM015164 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Sluggish cognitive tempo) — — partial R²: 0.00022 age, PCs1-3 —
PPM015166 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (stress) — — partial R²: 0.00057 age, PCs1-3 —
PPM015167 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture vocabulary) — — partial R²: 0.00079 age, PCs1-3 —
PPM015168 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Flanker test) — — partial R²: 0.00021 age, PCs1-3 —
PPM015169 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (list sorting) — — partial R²: 0.00022 age, PCs1-3 —
PPM015170 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (card sorting) — — partial R²: 4e-05 age, PCs1-3 —
PPM015171 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (pattern comparison) — — partial R²: 0.00016 age, PCs1-3 —
PPM015172 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture sequence) — — partial R²: 7e-05 age, PCs1-3 —
PPM015173 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (reading) — — partial R²: 0.00036 age, PCs1-3 —
PPM015174 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 5.31e-06 age, PCs1-3 —
PPM015175 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Crystallized composite) — — partial R²: 0.00072 age, PCs1-3 —
PPM015176 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Cognitive total) — — partial R²: 0.00027 age, PCs1-3 —
PPM015131 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 opppsit) — — partial R²: 2.94e-06 age, PCs1-3 —
PPM015143 PGS002787
(BD1_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 0.00151 age, PCs1-3 —
PPM015154 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (aggressive behaviour) — — partial R²: 0.00026 age, PCs1-3 —
PPM015165 PGS002787
(BD1_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Obsessive compulsive disorder) — — partial R²: 0.0001 age, PCs1-3 —
PPM015177 PGS002787
(BD1_SDPR)
 PSS009951|
European Ancestry|
78,561 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 0.00012 age, PCs1-10 the observed partial R² were higher than random R²s
PPM015179 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (withdrawn) — — partial R²: 3e-05 age, PCs1-3 —
PPM015180 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (somatic symptoms) — — partial R²: 0.00065 age, PCs1-3 —
PPM015181 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (social problems) — — partial R²: 0.00039 age, PCs1-3 —
PPM015182 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (thought problems) — — partial R²: 0.00024 age, PCs1-3 —
PPM015183 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (attention problems) — — partial R²: 0.00092 age, PCs1-3 —
PPM015185 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (aggressive behaviour) — — partial R²: 0.00217 age, PCs1-3 —
PPM015186 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (internalising) — — partial R²: 0.00055 age, PCs1-3 —
PPM015187 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (externalising) — — partial R²: 0.00192 age, PCs1-3 —
PPM015188 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (total problems) — — partial R²: 0.00114 age, PCs1-3 —
PPM015189 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 depression) — — partial R²: 2.60e-06 age, PCs1-3 —
PPM015190 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 anxety disorder) — — partial R²: 0.00045 age, PCs1-3 —
PPM015191 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 somatic problem) — — partial R²: 0.00071 age, PCs1-3 —
PPM015192 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 adhd) — — partial R²: 0.0006 age, PCs1-3 —
PPM015193 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 opppsit) — — partial R²: 0.00195 age, PCs1-3 —
PPM015194 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 conduct) — — partial R²: 0.00088 age, PCs1-3 —
PPM015196 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Obsessive compulsive disorder) — — partial R²: 0.00097 age, PCs1-3 —
PPM015197 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (stress) — — partial R²: 0.00138 age, PCs1-3 —
PPM015198 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture vocabulary) — — partial R²: 0.00049 age, PCs1-3 —
PPM015199 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Flanker test) — — partial R²: 0.00024 age, PCs1-3 —
PPM015200 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (list sorting) — — partial R²: 0.00036 age, PCs1-3 —
PPM015201 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (card sorting) — — partial R²: 0.00014 age, PCs1-3 —
PPM015202 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (pattern comparison) — — partial R²: 6e-05 age, PCs1-3 —
PPM015203 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture sequence) — — partial R²: 0.00011 age, PCs1-3 —
PPM015204 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (reading) — — partial R²: 1e-05 age, PCs1-3 —
PPM015205 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 0.0003 age, PCs1-3 —
PPM015206 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Crystallized composite) — — partial R²: 6e-05 age, PCs1-3 —
PPM015207 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Cognitive total) — — partial R²: 0.00026 age, PCs1-3 —
PPM015209 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (anxious/depressed) — — partial R²: 0.00163 age, PCs1-3 —
PPM015210 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (withdrawn) — — partial R²: 0.00156 age, PCs1-3 —
PPM015211 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (somatic symptoms) — — partial R²: 0.00085 age, PCs1-3 —
PPM015212 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (social problems) — — partial R²: 0.00123 age, PCs1-3 —
PPM015213 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (thought problems) — — partial R²: 8e-05 age, PCs1-3 —
PPM015214 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (attention problems) — — partial R²: 3e-05 age, PCs1-3 —
PPM015215 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (rule breaking) — — partial R²: 0.00057 age, PCs1-3 —
PPM015216 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (aggressive behaviour) — — partial R²: 5e-05 age, PCs1-3 —
PPM015217 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (internalising) — — partial R²: 0.00197 age, PCs1-3 —
PPM015218 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (externalising) — — partial R²: 0.00016 age, PCs1-3 —
PPM015220 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 depression) — — partial R²: 0.0006 age, PCs1-3 —
PPM015221 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 anxety disorder) — — partial R²: 0.00145 age, PCs1-3 —
PPM015222 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 somatic problem) — — partial R²: 0.00071 age, PCs1-3 —
PPM015223 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 adhd) — — partial R²: 3e-05 age, PCs1-3 —
PPM015224 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 opppsit) — — partial R²: 3e-05 age, PCs1-3 —
PPM015225 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Dsm5 conduct) — — partial R²: 4e-05 age, PCs1-3 —
PPM015226 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Sluggish cognitive tempo) — — partial R²: 0.0001 age, PCs1-3 —
PPM015227 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Obsessive compulsive disorder) — — partial R²: 0.00125 age, PCs1-3 —
PPM015228 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (stress) — — partial R²: 0.00025 age, PCs1-3 —
PPM015230 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Flanker test) — — partial R²: 1.91e-06 age, PCs1-3 —
PPM015231 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (list sorting) — — partial R²: 3.47e-06 age, PCs1-3 —
PPM015232 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (card sorting) — — partial R²: 8.67e-06 age, PCs1-3 —
PPM015233 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (pattern comparison) — — partial R²: 9.91e-06 age, PCs1-3 —
PPM015234 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture sequence) — — partial R²: 7e-05 age, PCs1-3 —
PPM015235 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (reading) — — partial R²: 0.0001 age, PCs1-3 —
PPM015236 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 3e-05 age, PCs1-3 —
PPM015237 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Crystallized composite) — — partial R²: 7e-05 age, PCs1-3 —
PPM015238 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Cognitive total) — — partial R²: 3.27e-06 age, PCs1-3 —
PPM015239 PGS002788
(BD2_SDPR)
 PSS009951|
European Ancestry|
78,561 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 5.36e-06 age, PCs1-10 —
PPM015178 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (anxious/depressed) — — partial R²: 0.00052 age, PCs1-3 —
PPM015184 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (rule breaking) — — partial R²: 0.00084 age, PCs1-3 —
PPM015195 PGS002788
(BD2_SDPR)
 PSS009950|
European Ancestry|
2,524 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (Sluggish cognitive tempo) — — partial R²: 0.00307 age, PCs1-3 —
PPM015208 PGS002788
(BD2_SDPR)
 PSS009953|
European Ancestry|
68,614 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (fluid composite) — — partial R²: 9.85e-06 age, PCs1-10 —
PPM015219 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Psychiatric behavior (total problems) — — partial R²: 0.00068 age, PCs1-3 —
PPM015229 PGS002788
(BD2_SDPR)
 PSS009949|
European Ancestry|
2,198 individuals
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Reported Trait: Cognitive function (Picture vocabulary) — — partial R²: 0.00035 age, PCs1-3 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009949 NIH Toolbox was used to measure cognition in ABCD. Children’s problems and competencies were rated using the parent-reported Children Behavior Checklist (CBCL). Details of the ABCD MRI data acquisition and analysis have been published previously. — 2,198 individuals,
0.0 % Male samples
 Mean = 9.89 years
Sd = 0.61 years		 European — ABCD —
PSS009950 NIH Toolbox was used to measure cognition in ABCD. Children’s problems and competencies were rated using the parent-reported Children Behavior Checklist (CBCL). Details of the ABCD MRI data acquisition and analysis have been published previously. — 2,524 individuals,
100.0 % Male samples
 Mean = 9.92 years
Sd = 0.62 years		 European — ABCD —
PSS009951 Fluid intelligence test — 78,561 individuals,
0.0 % Male samples
 Mean = 57.46 years
Sd = 8.08 years		 European — UKB —
PSS009952 imaging-derived phenotypes (IDPs) generated by an image-processing pipeline developed and ran on behalf of the UKB — 10,343 individuals,
0.0 % Male samples
 Mean = 63.13 years
Sd = 7.3 years		 European — UKB —
PSS009953 Fluid intelligence test — 68,614 individuals,
100.0 % Male samples
 Mean = 58.39 years
Sd = 8.36 years		 European — UKB —