Trait: inflammatory bowel disease

Experimental Factor Ontology (EFO) Information
Identifier EFO_0003767
Description A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type. [NCIT: C3138]
Trait categories
Digestive system disorder
Immune system disorder
Synonyms 6 synonyms
  • Bowel Diseases, Inflammatory
  • IBD
  • INFLAMM BOWEL DIS
  • Inflammatory Bowel Diseases
  • autoimmune bowel disorder
  • inflammatory bowel disease
Mapped terms 22 mapped terms
  • DOID:0050589
  • ICD9:558.9
  • MEDGEN:43877
  • MESH:D015212
  • MONDO:0005265
  • MeSH:D015212
  • MedDRA:10021184
  • MedDRA:10021972
  • NANDO:2100259
  • NCIT:C3138
  • NCIt:C3138
  • OMIM:608448
  • OMIM:611081
  • OMIM:612244
  • OMIM:612245
  • OMIM:612261
  • OMIM:612278
  • OMIM:618077
  • OMIMPS:266600
  • SCTID:24526004
  • SNOMEDCT:24526004
  • UMLS:C0021390
Child trait(s) 3 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "inflammatory bowel disease" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000017
(GPS_IBD)
 PGP000006 |
Khera AV et al. Nat Genet (2018)
 Inflammatory bowel disease inflammatory bowel disease 6,907,112
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000017/ScoringFiles/PGS000017.txt.gz - Check Terms/Licenses
PGS001288
(GBE_HC95)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Inflammatory bowel disease inflammatory bowel disease 195
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001288/ScoringFiles/PGS001288.txt.gz
PGS001306
(GBE_HC201)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ulcerative colitis ulcerative colitis 179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001306/ScoringFiles/PGS001306.txt.gz
PGS001307
(GBE_HC1102)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ulcerative colitis (time-to-event) ulcerative colitis 809
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001307/ScoringFiles/PGS001307.txt.gz
PGS001330
(GBE_HC1101)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Crohn's disease [regional enteritis] (time-to-event) Crohn's disease 220
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001330/ScoringFiles/PGS001330.txt.gz
PGS001331
(GBE_HC322)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Crohn's disease Crohn's disease 257
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001331/ScoringFiles/PGS001331.txt.gz
PGS001369
(GBE_HC1090)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Acute appendicitis (time-to-event) appendicitis 4
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001369/ScoringFiles/PGS001369.txt.gz
PGS001785
(1kgeur_gbmi_leaveUKBBout_AcApp_pst_eff_a1_b0.5_phiauto)
 PGP000262 |
Wang Y et al. Cell Genom (2023)
 Acute appendicitis appendicitis 911,334
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001785/ScoringFiles/PGS001785.txt.gz
PGS001855
(portability-PLR_555.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ulcerative colitis ulcerative colitis 1,505
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001855/ScoringFiles/PGS001855.txt.gz
PGS002066
(portability-ldpred2_555.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ulcerative colitis ulcerative colitis 566,637
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002066/ScoringFiles/PGS002066.txt.gz
PGS003981
(dbslmm.auto.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,103,311
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003981/ScoringFiles/PGS003981.txt.gz
PGS003997
(lassosum.auto.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 8,406
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003997/ScoringFiles/PGS003997.txt.gz
PGS004013
(lassosum.CV.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 22,690
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004013/ScoringFiles/PGS004013.txt.gz
PGS004023
(ldpred2.auto.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,018,068
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004023/ScoringFiles/PGS004023.txt.gz
PGS004038
(ldpred2.CV.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,018,068
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004038/ScoringFiles/PGS004038.txt.gz
PGS004051
(megaprs.auto.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 784,928
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004051/ScoringFiles/PGS004051.txt.gz
PGS004067
(megaprs.CV.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 784,928
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004067/ScoringFiles/PGS004067.txt.gz
PGS004081
(prscs.auto.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,073,268
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004081/ScoringFiles/PGS004081.txt.gz
PGS004097
(prscs.CV.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,073,268
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004097/ScoringFiles/PGS004097.txt.gz
PGS004105
(pt_clump.auto.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 139
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004105/ScoringFiles/PGS004105.txt.gz
PGS004121
(pt_clump_nested.CV.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 774
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004121/ScoringFiles/PGS004121.txt.gz
PGS004135
(sbayesr.auto.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 912,746
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004135/ScoringFiles/PGS004135.txt.gz
PGS004151
(UKBB_EnsPGS.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,102,205
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004151/ScoringFiles/PGS004151.txt.gz
PGS004253
(uc_ldpred2)
 PGP000545 |
Middha P et al. Nat Commun (2024)
 Ulcerative colitis ulcerative colitis 744,575
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004253/ScoringFiles/PGS004253.txt.gz
PGS004254
(cd_ldpred2)
 PGP000545 |
Middha P et al. Nat Commun (2024)
 Crohn's disease Crohn's disease 744,682
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004254/ScoringFiles/PGS004254.txt.gz
PGS004270
(GenoBoost_inflammatory_bowel_disease_0)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Inflammatory bowel disease inflammatory bowel disease 20
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004270/ScoringFiles/PGS004270.txt.gz
PGS004271
(GenoBoost_inflammatory_bowel_disease_1)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Inflammatory bowel disease inflammatory bowel disease 20
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004271/ScoringFiles/PGS004271.txt.gz
PGS004272
(GenoBoost_inflammatory_bowel_disease_2)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Inflammatory bowel disease inflammatory bowel disease 100
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004272/ScoringFiles/PGS004272.txt.gz
PGS004273
(GenoBoost_inflammatory_bowel_disease_3)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Inflammatory bowel disease inflammatory bowel disease 110
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004273/ScoringFiles/PGS004273.txt.gz
PGS004274
(GenoBoost_inflammatory_bowel_disease_4)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Inflammatory bowel disease inflammatory bowel disease 40
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004274/ScoringFiles/PGS004274.txt.gz
PGS004876
(INTERVENE_MegaPRS_Appendicitis)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Appendicitis appendicitis 601,835
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004876/ScoringFiles/PGS004876.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000026 PGS000017
(GPS_IBD)
 PSS000016|
European Ancestry|
288,978 individuals
 PGP000006 |
Khera AV et al. Nat Genet (2018)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.63 [0.62, 0.64] Nagelkerke’s R2 (estimate of variance explained by the PGS after covariate adjustment): 0.021 age; sex; Ancestry PC 1-4; genotyping chip —
PPM012874 PGS000017
(GPS_IBD)
 PSS009588|
European Ancestry|
1,433 individuals
 PGP000288 |
Garcia-Etxebarria K et al. Sci Rep (2022)
|Ext.		 Reported Trait: Inflammatory Bowel Disease — AUROC: 0.69 [0.66, 0.72] — — —
PPM008938 PGS001288
(GBE_HC95)
 PSS004741|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.64251 [0.54711, 0.73791] R²: 0.05914
Incremental AUROC (full-covars): 0.00245
PGS R2 (no covariates): 0.00027
PGS AUROC (no covariates): 0.52101 [0.42335, 0.61867]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008939 PGS001288
(GBE_HC95)
 PSS004742|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.89429 [0.79091, 0.99767] R²: 0.2051
Incremental AUROC (full-covars): -0.0033
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.48687 [0.28135, 0.6924]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008940 PGS001288
(GBE_HC95)
 PSS004743|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.63478 [0.60168, 0.66787] R²: 0.02287
Incremental AUROC (full-covars): 0.02492
PGS R2 (no covariates): 0.0102
PGS AUROC (no covariates): 0.58475 [0.55242, 0.61708]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008941 PGS001288
(GBE_HC95)
 PSS004744|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.66934 [0.62525, 0.71343] R²: 0.03759
Incremental AUROC (full-covars): 0.004
PGS R2 (no covariates): 0.00311
PGS AUROC (no covariates): 0.55448 [0.50125, 0.6077]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008942 PGS001288
(GBE_HC95)
 PSS004745|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.59461 [0.57544, 0.61378] R²: 0.01221
Incremental AUROC (full-covars): 0.06405
PGS R2 (no covariates): 0.01191
PGS AUROC (no covariates): 0.59586 [0.5768, 0.61492]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009024 PGS001306
(GBE_HC201)
 PSS004339|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Ulcerative colitis — AUROC: 0.62904 [0.5093, 0.74878] R²: 0.04535
Incremental AUROC (full-covars): -0.00864
PGS R2 (no covariates): 0.00044
PGS AUROC (no covariates): 0.51081 [0.37987, 0.64174]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009025 PGS001306
(GBE_HC201)
 PSS004340|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Ulcerative colitis — AUROC: 0.89429 [0.79357, 0.99502] R²: 0.20499
Incremental AUROC (full-covars): -0.0033
PGS R2 (no covariates): 2e-05
PGS AUROC (no covariates): 0.49111 [0.35854, 0.62368]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009026 PGS001306
(GBE_HC201)
 PSS004341|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Ulcerative colitis — AUROC: 0.66162 [0.6277, 0.69554] R²: 0.03336
Incremental AUROC (full-covars): 0.04247
PGS R2 (no covariates): 0.02036
PGS AUROC (no covariates): 0.63006 [0.5958, 0.66432]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009027 PGS001306
(GBE_HC201)
 PSS004342|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Ulcerative colitis — AUROC: 0.67522 [0.62537, 0.72506] R²: 0.03696
Incremental AUROC (full-covars): 0.01011
PGS R2 (no covariates): 0.00545
PGS AUROC (no covariates): 0.56552 [0.50815, 0.62289]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009028 PGS001306
(GBE_HC201)
 PSS004343|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Ulcerative colitis — AUROC: 0.6157 [0.59481, 0.63659] PGS R2 (no covariates): 0.0193
R²: 0.01676
Incremental AUROC (full-covars): 0.08728
PGS AUROC (no covariates): 0.62452 [0.60374, 0.6453]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009029 PGS001307
(GBE_HC1102)
 PSS004119|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE ulcerative colitis — AUROC: 0.62873 [0.51002, 0.74744] R²: 0.04344
Incremental AUROC (full-covars): -0.00895
PGS R2 (no covariates): 0.00027
PGS AUROC (no covariates): 0.50641 [0.39121, 0.62161]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009030 PGS001307
(GBE_HC1102)
 PSS004120|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE ulcerative colitis — AUROC: 0.89582 [0.79576, 0.99588] R²: 0.20607
Incremental AUROC (full-covars): -0.00177
PGS R2 (no covariates): 0.00203
PGS AUROC (no covariates): 0.55433 [0.4473, 0.66136]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009031 PGS001307
(GBE_HC1102)
 PSS004121|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE ulcerative colitis — AUROC: 0.65578 [0.62353, 0.68804] R²: 0.03272
Incremental AUROC (full-covars): 0.04212
PGS R2 (no covariates): 0.0169
PGS AUROC (no covariates): 0.6106 [0.57717, 0.64402]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009032 PGS001307
(GBE_HC1102)
 PSS004122|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE ulcerative colitis — AUROC: 0.66008 [0.61042, 0.70974] R²: 0.03192
Incremental AUROC (full-covars): 0.00203
PGS R2 (no covariates): 0.0036
PGS AUROC (no covariates): 0.55808 [0.506, 0.61016]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009033 PGS001307
(GBE_HC1102)
 PSS004123|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE ulcerative colitis — AUROC: 0.63965 [0.62036, 0.65895] R²: 0.02376
Incremental AUROC (full-covars): 0.1085
PGS R2 (no covariates): 0.02383
PGS AUROC (no covariates): 0.63847 [0.61861, 0.65833]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009137 PGS001330
(GBE_HC1101)
 PSS004114|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE crohn's disease [regional enteritis] — AUROC: 0.66243 [0.55234, 0.77252] R²: 0.05286
Incremental AUROC (full-covars): -0.02175
PGS R2 (no covariates): 0.00138
PGS AUROC (no covariates): 0.46272 [0.36718, 0.55826]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009138 PGS001330
(GBE_HC1101)
 PSS004115|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE crohn's disease [regional enteritis] — AUROC: 0.86369 [0.7806, 0.94678] R²: 0.13339
Incremental AUROC (full-covars): 0.0
PGS R2 (no covariates): 0.14319
PGS AUROC (no covariates): 0.10664 [0.0, 0.28372]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009139 PGS001330
(GBE_HC1101)
 PSS004116|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE crohn's disease [regional enteritis] — AUROC: 0.60269 [0.55209, 0.65328] R²: 0.01102
Incremental AUROC (full-covars): 0.02413
PGS R2 (no covariates): 0.00621
PGS AUROC (no covariates): 0.57593 [0.52318, 0.62867]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009140 PGS001330
(GBE_HC1101)
 PSS004117|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE crohn's disease [regional enteritis] — AUROC: 0.69933 [0.63548, 0.76318] R²: 0.0344
Incremental AUROC (full-covars): 0.00201
PGS R2 (no covariates): 0.00147
PGS AUROC (no covariates): 0.53846 [0.46042, 0.6165]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009141 PGS001330
(GBE_HC1101)
 PSS004118|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE crohn's disease [regional enteritis] — AUROC: 0.55852 [0.52842, 0.58862] R²: 0.00474
Incremental AUROC (full-covars): 0.07412
PGS R2 (no covariates): 0.00669
PGS AUROC (no covariates): 0.5714 [0.54073, 0.60207]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009142 PGS001331
(GBE_HC322)
 PSS004442|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Crohns disease — AUROC: 0.65892 [0.54485, 0.77299] R²: 0.05502
Incremental AUROC (full-covars): -0.02526
PGS R2 (no covariates): 4e-05
PGS AUROC (no covariates): 0.49152 [0.37858, 0.60446]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009143 PGS001331
(GBE_HC322)
 PSS004444|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Crohns disease — AUROC: 0.61269 [0.55802, 0.66736] R²: 0.01161
Incremental AUROC (full-covars): 0.02705
PGS R2 (no covariates): 0.00677
PGS AUROC (no covariates): 0.57919 [0.52051, 0.63786]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009144 PGS001331
(GBE_HC322)
 PSS004445|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Crohns disease — AUROC: 0.71 [0.64649, 0.7735] R²: 0.03928
Incremental AUROC (full-covars): 0.01378
PGS R2 (no covariates): 0.00366
PGS AUROC (no covariates): 0.56349 [0.47905, 0.64793]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009145 PGS001331
(GBE_HC322)
 PSS004446|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Crohns disease — AUROC: 0.56362 [0.53297, 0.59427] R²: 0.00529
Incremental AUROC (full-covars): 0.06267
PGS R2 (no covariates): 0.0063
PGS AUROC (no covariates): 0.57326 [0.54246, 0.60406]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005205 PGS001369
(GBE_HC1090)
 PSS004099|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE acute appendicitis — AUROC: 0.62041 [0.53518, 0.70564] R²: 0.03016
Incremental AUROC (full-covars): -0.00198
PGS R2 (no covariates): 0.00105
PGS AUROC (no covariates): 0.47489 [0.37525, 0.57453]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005206 PGS001369
(GBE_HC1090)
 PSS004100|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE acute appendicitis — AUROC: 0.8493 [0.77779, 0.9208] R²: 0.14577
Incremental AUROC (full-covars): 0.00105
PGS R2 (no covariates): 0.00332
PGS AUROC (no covariates): 0.51032 [0.33889, 0.68176]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005207 PGS001369
(GBE_HC1090)
 PSS004101|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE acute appendicitis — AUROC: 0.56849 [0.52835, 0.60862] R²: 0.00702
Incremental AUROC (full-covars): -0.00219
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.49616 [0.45378, 0.53854]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005208 PGS001369
(GBE_HC1090)
 PSS004102|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE acute appendicitis — AUROC: 0.72977 [0.65912, 0.80042] Incremental AUROC (full-covars): 0.00039
PGS R2 (no covariates): 0.00096
R²: 0.05613
PGS AUROC (no covariates): 0.5334 [0.44427, 0.62254]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005209 PGS001369
(GBE_HC1090)
 PSS004103|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE acute appendicitis — AUROC: 0.57413 [0.55138, 0.59688] R²: 0.00617
Incremental AUROC (full-covars): 0.00987
PGS R2 (no covariates): 0.00332
PGS AUROC (no covariates): 0.55036 [0.52746, 0.57326]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009289 PGS001785
(1kgeur_gbmi_leaveUKBBout_AcApp_pst_eff_a1_b0.5_phiauto)
 PSS007708|
European Ancestry|
359,031 individuals
 PGP000262 |
Wang Y et al. Cell Genom (2023)
 Reported Trait: Acute appendicitis — AUROC: 0.584 Nagelkerke's R2 (covariates regressed out): 0.00406 sex,age,age2,age*sex,age^2*sex, 20PCs —
PPM009730 PGS001855
(portability-PLR_555.2)
 PSS009330|
European Ancestry|
16,188 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0625 [0.0471, 0.0778] sex, age, birth date, deprivation index, 16 PCs —
PPM009732 PGS001855
(portability-PLR_555.2)
 PSS008658|
European Ancestry|
5,477 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0453 [0.0188, 0.0717] sex, age, birth date, deprivation index, 16 PCs —
PPM009733 PGS001855
(portability-PLR_555.2)
 PSS008432|
Greater Middle Eastern Ancestry|
1,007 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0175 [-0.0449, 0.0799] sex, age, birth date, deprivation index, 16 PCs —
PPM009734 PGS001855
(portability-PLR_555.2)
 PSS008212|
South Asian Ancestry|
5,337 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0407 [0.0139, 0.0676] sex, age, birth date, deprivation index, 16 PCs —
PPM009735 PGS001855
(portability-PLR_555.2)
 PSS007994|
East Asian Ancestry|
1,630 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0382 [-0.0107, 0.0868] sex, age, birth date, deprivation index, 16 PCs —
PPM009736 PGS001855
(portability-PLR_555.2)
 PSS007777|
African Ancestry|
2,105 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.031 [-0.0119, 0.0738] sex, age, birth date, deprivation index, 16 PCs —
PPM009737 PGS001855
(portability-PLR_555.2)
 PSS008881|
African Ancestry|
3,465 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): -0.0003 [-0.0337, 0.0331] sex, age, birth date, deprivation index, 16 PCs —
PPM009731 PGS001855
(portability-PLR_555.2)
 PSS009104|
European Ancestry|
3,520 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0367 [0.0036, 0.0698] sex, age, birth date, deprivation index, 16 PCs —
PPM011390 PGS002066
(portability-ldpred2_555.2)
 PSS009330|
European Ancestry|
16,188 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0641 [0.0487, 0.0794] sex, age, birth date, deprivation index, 16 PCs —
PPM011391 PGS002066
(portability-ldpred2_555.2)
 PSS009104|
European Ancestry|
3,520 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0466 [0.0135, 0.0796] sex, age, birth date, deprivation index, 16 PCs —
PPM011392 PGS002066
(portability-ldpred2_555.2)
 PSS008658|
European Ancestry|
5,477 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0426 [0.0161, 0.0691] sex, age, birth date, deprivation index, 16 PCs —
PPM011393 PGS002066
(portability-ldpred2_555.2)
 PSS008432|
Greater Middle Eastern Ancestry|
1,007 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0056 [-0.0568, 0.068] sex, age, birth date, deprivation index, 16 PCs —
PPM011395 PGS002066
(portability-ldpred2_555.2)
 PSS007994|
East Asian Ancestry|
1,630 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0398 [-0.009, 0.0885] sex, age, birth date, deprivation index, 16 PCs —
PPM011396 PGS002066
(portability-ldpred2_555.2)
 PSS007777|
African Ancestry|
2,105 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0272 [-0.0157, 0.0701] sex, age, birth date, deprivation index, 16 PCs —
PPM011397 PGS002066
(portability-ldpred2_555.2)
 PSS008881|
African Ancestry|
3,465 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0058 [-0.0276, 0.0392] sex, age, birth date, deprivation index, 16 PCs —
PPM011394 PGS002066
(portability-ldpred2_555.2)
 PSS008212|
South Asian Ancestry|
5,337 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ulcerative colitis — — Partial Correlation (partial-r): 0.0388 [0.0119, 0.0656] sex, age, birth date, deprivation index, 16 PCs —
PPM021728 PGS002066
(portability-ldpred2_555.2)
 PSS011762|
European Ancestry|
8,417 individuals
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
|Ext.		 Reported Trait: Ulcerative colitis OR: 1.11 [0.97, 1.28] AUROC: 0.57 — — —
PPM019233 PGS003981
(dbslmm.auto.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.33244
β: 0.28701		 AUROC: 0.58 — 0 beta = log(or)/sd_pgs
PPM019234 PGS003981
(dbslmm.auto.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.89729
β: 0.64043		 AUROC: 0.67 — 0 beta = log(or)/sd_pgs
PPM019235 PGS003981
(dbslmm.auto.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.82983
β: 0.60422		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019236 PGS003981
(dbslmm.auto.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.51174
β: 0.41326		 AUROC: 0.61 — 0 beta = log(or)/sd_pgs
PPM019237 PGS003981
(dbslmm.auto.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.62008
β: 0.48247		 AUROC: 0.63 — 0 beta = log(or)/sd_pgs
PPM019238 PGS003981
(dbslmm.auto.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.8704
β: 0.62615		 AUROC: 0.67 — 0 beta = log(or)/sd_pgs
PPM019287 PGS003997
(lassosum.auto.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.35075
β: 0.30066		 AUROC: 0.58 — 0 beta = log(or)/sd_pgs
PPM019288 PGS003997
(lassosum.auto.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.94603
β: 0.66579		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019289 PGS003997
(lassosum.auto.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.83801
β: 0.60869		 AUROC: 0.67 — 0 beta = log(or)/sd_pgs
PPM019290 PGS003997
(lassosum.auto.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.53922
β: 0.43128		 AUROC: 0.62 — 0 beta = log(or)/sd_pgs
PPM019291 PGS003997
(lassosum.auto.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.73594
β: 0.55155		 AUROC: 0.65 — 0 beta = log(or)/sd_pgs
PPM019292 PGS003997
(lassosum.auto.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.84612
β: 0.61309		 AUROC: 0.67 — 0 beta = log(or)/sd_pgs
PPM019281 PGS004013
(lassosum.CV.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.37266
β: 0.31675		 AUROC: 0.58 — 0 beta = log(or)/sd_pgs
PPM019282 PGS004013
(lassosum.CV.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.95504
β: 0.67041		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019283 PGS004013
(lassosum.CV.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.88804
β: 0.63554		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019284 PGS004013
(lassosum.CV.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.53614
β: 0.42927		 AUROC: 0.62 — 0 beta = log(or)/sd_pgs
PPM019285 PGS004013
(lassosum.CV.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.72939
β: 0.54777		 AUROC: 0.65 — 0 beta = log(or)/sd_pgs
PPM019286 PGS004013
(lassosum.CV.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.8643
β: 0.62289		 AUROC: 0.67 — 0 beta = log(or)/sd_pgs
PPM019252 PGS004023
(ldpred2.auto.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.98269
β: 0.68445		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019253 PGS004023
(ldpred2.auto.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.96487
β: 0.67543		 AUROC: 0.69 — 0 beta = log(or)/sd_pgs
PPM019254 PGS004023
(ldpred2.auto.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.53961
β: 0.43153		 AUROC: 0.62 — 0 beta = log(or)/sd_pgs
PPM019255 PGS004023
(ldpred2.auto.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.7204
β: 0.54256		 AUROC: 0.64 — 0 beta = log(or)/sd_pgs
PPM019256 PGS004023
(ldpred2.auto.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.95616
β: 0.67098		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019251 PGS004023
(ldpred2.auto.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.37223
β: 0.31644		 AUROC: 0.58 — 0 beta = log(or)/sd_pgs
PPM019215 PGS004038
(ldpred2.CV.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.3661
β: 0.31196		 AUROC: 0.58 — 0 beta = log(or)/sd_pgs
PPM019216 PGS004038
(ldpred2.CV.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 2.00709
β: 0.69669		 AUROC: 0.69 — 0 beta = log(or)/sd_pgs
PPM019217 PGS004038
(ldpred2.CV.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.946
β: 0.66578		 AUROC: 0.69 — 0 beta = log(or)/sd_pgs
PPM019218 PGS004038
(ldpred2.CV.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.55477
β: 0.44133		 AUROC: 0.62 — 0 beta = log(or)/sd_pgs
PPM019219 PGS004038
(ldpred2.CV.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.71999
β: 0.54232		 AUROC: 0.64 — 0 beta = log(or)/sd_pgs
PPM019220 PGS004038
(ldpred2.CV.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.96885
β: 0.67745		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019257 PGS004051
(megaprs.auto.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.36888
β: 0.314		 AUROC: 0.58 — 0 beta = log(or)/sd_pgs
PPM019258 PGS004051
(megaprs.auto.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 2.00653
β: 0.69641		 AUROC: 0.69 — 0 beta = log(or)/sd_pgs
PPM019259 PGS004051
(megaprs.auto.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.90388
β: 0.64389		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019260 PGS004051
(megaprs.auto.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.53763
β: 0.43024		 AUROC: 0.62 — 0 beta = log(or)/sd_pgs
PPM019261 PGS004051
(megaprs.auto.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.63845
β: 0.49375		 AUROC: 0.63 — 0 beta = log(or)/sd_pgs
PPM019262 PGS004051
(megaprs.auto.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.9624
β: 0.67417		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019263 PGS004067
(megaprs.CV.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.38476
β: 0.32553		 AUROC: 0.59 — 0 beta = log(or)/sd_pgs
PPM019264 PGS004067
(megaprs.CV.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 2.01137
β: 0.69881		 AUROC: 0.69 — 0 beta = log(or)/sd_pgs
PPM019265 PGS004067
(megaprs.CV.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.90373
β: 0.64382		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019266 PGS004067
(megaprs.CV.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.53272
β: 0.42704		 AUROC: 0.62 — 0 beta = log(or)/sd_pgs
PPM019267 PGS004067
(megaprs.CV.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.64423
β: 0.49727		 AUROC: 0.63 — 0 beta = log(or)/sd_pgs
PPM019268 PGS004067
(megaprs.CV.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.9918
β: 0.68904		 AUROC: 0.69 — 0 beta = log(or)/sd_pgs
PPM019275 PGS004081
(prscs.auto.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.33947
β: 0.29227		 AUROC: 0.58 — 0 beta = log(or)/sd_pgs
PPM019276 PGS004081
(prscs.auto.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.93798
β: 0.66165		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019277 PGS004081
(prscs.auto.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.81701
β: 0.59719		 AUROC: 0.67 — 0 beta = log(or)/sd_pgs
PPM019278 PGS004081
(prscs.auto.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.52897
β: 0.4246		 AUROC: 0.62 — 0 beta = log(or)/sd_pgs
PPM019279 PGS004081
(prscs.auto.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.64491
β: 0.49768		 AUROC: 0.63 — 0 beta = log(or)/sd_pgs
PPM019280 PGS004081
(prscs.auto.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.87137
β: 0.62667		 AUROC: 0.67 — 0 beta = log(or)/sd_pgs
PPM019269 PGS004097
(prscs.CV.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.33762
β: 0.29089		 AUROC: 0.58 — 0 beta = log(or)/sd_pgs
PPM019270 PGS004097
(prscs.CV.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.9368
β: 0.66104		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019271 PGS004097
(prscs.CV.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.81277
β: 0.59485		 AUROC: 0.67 — 0 beta = log(or)/sd_pgs
PPM019272 PGS004097
(prscs.CV.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.53892
β: 0.43108		 AUROC: 0.62 — 0 beta = log(or)/sd_pgs
PPM019273 PGS004097
(prscs.CV.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.64559
β: 0.4981		 AUROC: 0.63 — 0 beta = log(or)/sd_pgs
PPM019274 PGS004097
(prscs.CV.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.86814
β: 0.62494		 AUROC: 0.67 — 0 beta = log(or)/sd_pgs
PPM019221 PGS004105
(pt_clump.auto.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.24143
β: 0.21627		 AUROC: 0.56 — 0 beta = log(or)/sd_pgs
PPM019222 PGS004105
(pt_clump.auto.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.63002
β: 0.48859		 AUROC: 0.63 — 0 beta = log(or)/sd_pgs
PPM019223 PGS004105
(pt_clump.auto.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.40101
β: 0.33719		 AUROC: 0.6 — 0 beta = log(or)/sd_pgs
PPM019224 PGS004105
(pt_clump.auto.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.35946
β: 0.30709		 AUROC: 0.58 — 0 beta = log(or)/sd_pgs
PPM019225 PGS004105
(pt_clump.auto.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.34635
β: 0.29739		 AUROC: 0.59 — 0 beta = log(or)/sd_pgs
PPM019226 PGS004105
(pt_clump.auto.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.59062
β: 0.46412		 AUROC: 0.63 — 0 beta = log(or)/sd_pgs
PPM019227 PGS004121
(pt_clump_nested.CV.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.27323
β: 0.24156		 AUROC: 0.56 — 0 beta = log(or)/sd_pgs
PPM019228 PGS004121
(pt_clump_nested.CV.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.74769
β: 0.55829		 AUROC: 0.65 — 0 beta = log(or)/sd_pgs
PPM019229 PGS004121
(pt_clump_nested.CV.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.51461
β: 0.41516		 AUROC: 0.61 — 0 beta = log(or)/sd_pgs
PPM019230 PGS004121
(pt_clump_nested.CV.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.38976
β: 0.32913		 AUROC: 0.59 — 0 beta = log(or)/sd_pgs
PPM019231 PGS004121
(pt_clump_nested.CV.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.49325
β: 0.40096		 AUROC: 0.62 — 0 beta = log(or)/sd_pgs
PPM019232 PGS004121
(pt_clump_nested.CV.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.68525
β: 0.52191		 AUROC: 0.65 — 0 beta = log(or)/sd_pgs
PPM019245 PGS004135
(sbayesr.auto.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.33765
β: 0.29091		 AUROC: 0.58 — 0 beta = log(or)/sd_pgs
PPM019247 PGS004135
(sbayesr.auto.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.8584
β: 0.61972		 AUROC: 0.67 — 0 beta = log(or)/sd_pgs
PPM019248 PGS004135
(sbayesr.auto.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.53371
β: 0.42769		 AUROC: 0.61 — 0 beta = log(or)/sd_pgs
PPM019249 PGS004135
(sbayesr.auto.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.68556
β: 0.5221		 AUROC: 0.65 — 0 beta = log(or)/sd_pgs
PPM019250 PGS004135
(sbayesr.auto.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.91118
β: 0.64772		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019246 PGS004135
(sbayesr.auto.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.982
β: 0.68411		 AUROC: 0.68 — 0 beta = log(or)/sd_pgs
PPM019239 PGS004151
(UKBB_EnsPGS.GCST004131.IBD)
 PSS011220|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.39728
β: 0.33453		 AUROC: 0.59 — 0 beta = log(or)/sd_pgs
PPM019240 PGS004151
(UKBB_EnsPGS.GCST004131.IBD)
 PSS011231|
European Ancestry|
396,819 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 2.06398
β: 0.72464		 AUROC: 0.69 — 0 beta = log(or)/sd_pgs
PPM019241 PGS004151
(UKBB_EnsPGS.GCST004131.IBD)
 PSS011244|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.99477
β: 0.69053		 AUROC: 0.69 — 0 beta = log(or)/sd_pgs
PPM019242 PGS004151
(UKBB_EnsPGS.GCST004131.IBD)
 PSS011260|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.58122
β: 0.4582		 AUROC: 0.62 — 0 beta = log(or)/sd_pgs
PPM019243 PGS004151
(UKBB_EnsPGS.GCST004131.IBD)
 PSS011288|
South Asian Ancestry|
9,326 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 1.76291
β: 0.56697		 AUROC: 0.65 — 0 beta = log(or)/sd_pgs
PPM019244 PGS004151
(UKBB_EnsPGS.GCST004131.IBD)
 PSS011273|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Inflammatory bowel disease OR: 2.04212
β: 0.71399		 AUROC: 0.69 — 0 beta = log(or)/sd_pgs
PPM020320 PGS004253
(uc_ldpred2)
 PSS011334|
European Ancestry|
21,335 individuals
 PGP000545 |
Middha P et al. Nat Commun (2024)
 Reported Trait: Ulcerative colitis OR: 1.75 [1.59, 1.92] AUROC: 0.65 [0.62, 0.68] — age, sex, 10 PCs —
PPM020319 PGS004253
(uc_ldpred2)
 PSS011335|
European Ancestry|
5,735 individuals
 PGP000545 |
Middha P et al. Nat Commun (2024)
 Reported Trait: Ulcerative colitis OR: 1.84 [1.76, 1.93] AUROC: 0.66 [0.64, 0.68] — age at diagnosis/enrollment, sex, genotyping array, 10 PCs —
PPM020321 PGS004254
(cd_ldpred2)
 PSS011333|
European Ancestry|
5,285 individuals
 PGP000545 |
Middha P et al. Nat Commun (2024)
 Reported Trait: Crohn's disease OR: 1.83 [1.72, 1.95] AUROC: 0.72 [0.69, 0.74] — age at diagnosis/enrollment, sex, genotyping array, 10 PCs —
PPM020322 PGS004254
(cd_ldpred2)
 PSS011332|
European Ancestry|
22,296 individuals
 PGP000545 |
Middha P et al. Nat Commun (2024)
 Reported Trait: Crohn's disease OR: 2.18 [2.05, 2.32] AUROC: 0.72 [0.7, 0.73] — age, sex, 10 PCs —
PPM020338 PGS004270
(GenoBoost_inflammatory_bowel_disease_0)
 PSS011341|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.57093 Covariate-adjusted pseudo-R2: 0.00624
AUPRC: 0.01652		 age, sex, PC1-10 —
PPM020339 PGS004271
(GenoBoost_inflammatory_bowel_disease_1)
 PSS011341|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.57758 Covariate-adjusted pseudo-R2: 0.00673
AUPRC: 0.01694		 age, sex, PC1-10 —
PPM020340 PGS004272
(GenoBoost_inflammatory_bowel_disease_2)
 PSS011341|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.58326 Covariate-adjusted pseudo-R2: 0.00796
AUPRC: 0.0168		 age, sex, PC1-10 —
PPM020341 PGS004273
(GenoBoost_inflammatory_bowel_disease_3)
 PSS011341|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.58873 Covariate-adjusted pseudo-R2: 0.00874
AUPRC: 0.01624		 age, sex, PC1-10 —
PPM020342 PGS004274
(GenoBoost_inflammatory_bowel_disease_4)
 PSS011341|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Inflammatory bowel disease — AUROC: 0.5879 Covariate-adjusted pseudo-R2: 0.00872
AUPRC: 0.01705		 age, sex, PC1-10 —
PPM021188 PGS004876
(INTERVENE_MegaPRS_Appendicitis)
 PSS011551|
European Ancestry|
38,191 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident Appendicitis HR: 1.04 [0.96, 1.14] C-index: 0.58 [0.55, 0.61] — PCs 1-10 —
PPM021189 PGS004876
(INTERVENE_MegaPRS_Appendicitis)
 PSS011550|
European Ancestry|
69,715 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident Appendicitis HR: 1.07 [1.02, 1.12] C-index: 0.54 [0.53, 0.56] — PCs 1-10 —
PPM021190 PGS004876
(INTERVENE_MegaPRS_Appendicitis)
 PSS011549|
European Ancestry|
29,427 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident Appendicitis HR: 1.1 [1.01, 1.19] C-index: 0.56 [0.53, 0.58] — PCs 1-10 —
PPM021191 PGS004876
(INTERVENE_MegaPRS_Appendicitis)
 PSS011547|
European Ancestry|
44,188 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident Appendicitis HR: 1.06 [0.97, 1.16] — — PCs 1-10 —
PPM021192 PGS004876
(INTERVENE_MegaPRS_Appendicitis)
 PSS011548|
European Ancestry|
7,018 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident Appendicitis HR: 1.1 [1.01, 1.2] C-index: 0.57 [0.54, 0.59] — PCs 1-10 —
PPM021193 PGS004876
(INTERVENE_MegaPRS_Appendicitis)
 PSS011546|
European Ancestry|
412,090 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident Appendicitis HR: 1.07 [1.06, 1.08] C-index: 0.53 [0.52, 0.53] — PCs 1-10 —
PPM021194 PGS004876
(INTERVENE_MegaPRS_Appendicitis)
 PSS011545|
European Ancestry|
199,868 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident Appendicitis HR: 1.05 [1.03, 1.07] C-index: 0.54 [0.53, 0.54] — PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011273 — —
[
  • 1,335 cases
  • , 88,939 controls
]
 — European — UKB —
PSS008658 — — 5,477 individuals — European Italy (South Europe) UKB —
PSS011288 — —
[
  • 168 cases
  • , 9,158 controls
]
 — South Asian — UKB —
PSS011332 — —
[
  • 1,420 cases
  • , 20,876 controls
]
 — European — BioVU —
PSS011333 — —
[
  • 394 cases
  • , 4,891 controls
]
 — European — UKB —
PSS011334 — —
[
  • 459 cases
  • , 20,876 controls
]
 — European — BioVU —
PSS007777 — — 2,105 individuals — African American or Afro-Caribbean Carribean UKB —
PSS004442 — —
[
  • 20 cases
  • , 6,477 controls
]
 — African unspecified — UKB —
PSS011335 — —
[
  • 844 cases
  • , 4,891 controls
]
 — European — UKB —
PSS004444 — —
[
  • 105 cases
  • , 24,800 controls
]
 — European non-white British ancestry UKB —
PSS004445 — —
[
  • 42 cases
  • , 7,789 controls
]
 — South Asian — UKB —
PSS009588 — —
[
  • 498 cases
  • , 935 controls
]
 — European — BV —
PSS004446 — —
[
  • 361 cases
  • , 67,064 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS008432 — — 1,007 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009330 — — 16,188 individuals — European UK (+ Ireland) UKB —
PSS011341 — —
[
  • 763 cases
  • , 66,665 controls
]
,
46.0 % Male samples
 — European
(White British)		 — UKB —
PSS004339 — —
[
  • 27 cases
  • , 6,470 controls
]
 — African unspecified — UKB —
PSS004340 — —
[
  • 5 cases
  • , 1,699 controls
]
 — East Asian — UKB —
PSS004341 — —
[
  • 239 cases
  • , 24,666 controls
]
 — European non-white British ancestry UKB —
PSS004342 — —
[
  • 103 cases
  • , 7,728 controls
]
 — South Asian — UKB —
PSS004343 — —
[
  • 720 cases
  • , 66,705 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS011545 — —
[
  • 13,442 cases
  • , 186,426 controls
]
 — European — EB —
PSS011546 — —
[
  • 31,397 cases
  • , 380,693 controls
]
 — European — FinnGen —
PSS011547 — —
[
  • 453 cases
  • , 43,735 controls
]
 — European — G&H —
PSS011548 — —
[
  • 519 cases
  • , 6,499 controls
]
 — European — GS:SFHS —
PSS011549 — —
[
  • 586 cases
  • , 28,841 controls
]
 — European — GEL —
PSS011550 — —
[
  • 1,768 cases
  • , 67,947 controls
]
 — European — HUNT —
PSS011551 — —
[
  • 527 cases
  • , 37,664 controls
]
 — European — MGBB —
PSS000016 Inflammatory bowel disease ascertainment was based on report in an interview with a trained nurse, or an ICD-9 code of 555.X or ICD-10 code of K51.X in hospitalization records. —
[
  • 5,853 cases
  • , 283,125 controls
]
 — European — UKB UKB Phase 2
PSS004099 — —
[
  • 35 cases
  • , 6,462 controls
]
 — African unspecified — UKB —
PSS004100 — —
[
  • 9 cases
  • , 1,695 controls
]
 — East Asian — UKB —
PSS004741 — —
[
  • 36 cases
  • , 6,461 controls
]
 — African unspecified — UKB —
PSS004742 — —
[
  • 5 cases
  • , 1,699 controls
]
 — East Asian — UKB —
PSS004743 — —
[
  • 284 cases
  • , 24,621 controls
]
 — European non-white British ancestry UKB —
PSS004744 — —
[
  • 125 cases
  • , 7,706 controls
]
 — South Asian — UKB —
PSS004745 — —
[
  • 892 cases
  • , 66,533 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004101 — —
[
  • 190 cases
  • , 24,715 controls
]
 — European non-white British ancestry UKB —
PSS004102 — —
[
  • 37 cases
  • , 7,794 controls
]
 — South Asian — UKB —
PSS004103 — —
[
  • 612 cases
  • , 66,813 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS008212 — — 5,337 individuals — South Asian India (South Asia) UKB —
PSS009104 — — 3,520 individuals — European Poland (NE Europe) UKB —
PSS011762 — — 8,417 individuals — European — BBofA —
PSS011220 — —
[
  • 197,177 cases
  • , 2,097 controls
]
 — European — EB —
PSS004114 — —
[
  • 20 cases
  • , 6,477 controls
]
 — African unspecified — UKB —
PSS004115 — —
[
  • 2 cases
  • , 1,702 controls
]
 — East Asian — UKB —
PSS004116 — —
[
  • 117 cases
  • , 24,788 controls
]
 — European non-white British ancestry UKB —
PSS004117 — —
[
  • 48 cases
  • , 7,783 controls
]
 — South Asian — UKB —
PSS004118 — —
[
  • 393 cases
  • , 67,032 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004119 — —
[
  • 27 cases
  • , 6,470 controls
]
 — African unspecified — UKB —
PSS004120 — —
[
  • 5 cases
  • , 1,699 controls
]
 — East Asian — UKB —
PSS004121 — —
[
  • 260 cases
  • , 24,645 controls
]
 — European non-white British ancestry UKB —
PSS004122 — —
[
  • 113 cases
  • , 7,718 controls
]
 — South Asian — UKB —
PSS004123 — —
[
  • 788 cases
  • , 66,637 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS011231 K11_IBD_STRICT, ICD10: K50|K51, ICD9: 555|556 —
[
  • 389,004 cases
  • , 7,815 controls
]
 — European — FinnGen —
PSS011244 — —
[
  • 43,591 cases
  • , 466 controls
]
 — South Asian — G&H —
PSS008881 — — 3,465 individuals — African unspecified Nigeria (West Africa) UKB —
PSS007708 — —
[
  • 2,985 cases
  • , 356,045 controls
]
 — European — UKB —
PSS011260 — —
[
  • 65,096 cases
  • , 1,769 controls
]
 — European — HUNT —
PSS007994 — — 1,630 individuals — East Asian China (East Asia) UKB —