| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0007660 |
| Description | Quantification of some aspect of neuroticism or neurotic behaviour, such as severity or frequency of neurotic behaviour. This is usually assessed via a standardised questionnaire. | Trait category |
Other measurement
|
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS001996 (portability-PLR_neuroticism) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Neuroticism score | neuroticism measurement | 54,715 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001996/ScoringFiles/PGS001996.txt.gz |
| PGS002213 (portability-ldpred2_neuroticism) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Neuroticism score | neuroticism measurement | 950,183 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002213/ScoringFiles/PGS002213.txt.gz |
| PGS002342 (mental_NEUROTICISM.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Neuroticism | neuroticism measurement | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002342/ScoringFiles/PGS002342.txt.gz |
| PGS002414 (mental_NEUROTICISM.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Neuroticism | neuroticism measurement | 3,578 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002414/ScoringFiles/PGS002414.txt.gz |
| PGS002463 (mental_NEUROTICISM.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Neuroticism | neuroticism measurement | 16,660 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002463/ScoringFiles/PGS002463.txt.gz |
| PGS002512 (mental_NEUROTICISM.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Neuroticism | neuroticism measurement | 103,865 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002512/ScoringFiles/PGS002512.txt.gz |
| PGS002561 (mental_NEUROTICISM.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Neuroticism | neuroticism measurement | 469 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002561/ScoringFiles/PGS002561.txt.gz |
| PGS002610 (mental_NEUROTICISM.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Neuroticism | neuroticism measurement | 196 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002610/ScoringFiles/PGS002610.txt.gz |
| PGS002659 (mental_NEUROTICISM.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Neuroticism | neuroticism measurement | 546,323 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002659/ScoringFiles/PGS002659.txt.gz |
| PGS002708 (mental_NEUROTICISM.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Neuroticism | neuroticism measurement | 989,963 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002708/ScoringFiles/PGS002708.txt.gz |
| PGS003565 (cont-decay-neuroticism) |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Neuroticism score | neuroticism measurement | 979,739 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003565/ScoringFiles/PGS003565.txt.gz |
| PGS004430 (X20127.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
Neuroticism score | neuroticism measurement | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004430/ScoringFiles/PGS004430.txt.gz |
| PGS004608 (neuroticism) |
PGP000584 | Forthman KL et al. J Psychiatr Res (2023) |
Neuroticism | neuroticism measurement | 1,000,537 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004608/ScoringFiles/PGS004608.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM010843 | PGS001996 (portability-PLR_neuroticism) |
PSS009479| European Ancestry| 16,206 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.1882 [0.1733, 0.203] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010844 | PGS001996 (portability-PLR_neuroticism) |
PSS009253| European Ancestry| 2,941 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.1696 [0.1341, 0.2046] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010845 | PGS001996 (portability-PLR_neuroticism) |
PSS008807| European Ancestry| 5,081 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.1732 [0.1464, 0.1998] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010846 | PGS001996 (portability-PLR_neuroticism) |
PSS008581| Greater Middle Eastern Ancestry| 632 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.1655 [0.0874, 0.2416] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010847 | PGS001996 (portability-PLR_neuroticism) |
PSS008359| South Asian Ancestry| 3,839 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.1307 [0.0994, 0.1618] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010848 | PGS001996 (portability-PLR_neuroticism) |
PSS008136| East Asian Ancestry| 1,138 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.1278 [0.0697, 0.185] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010849 | PGS001996 (portability-PLR_neuroticism) |
PSS007923| African Ancestry| 1,756 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.0778 [0.0308, 0.1243] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010850 | PGS001996 (portability-PLR_neuroticism) |
PSS009027| African Ancestry| 2,505 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.0476 [0.0083, 0.0867] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012551 | PGS002213 (portability-ldpred2_neuroticism) |
PSS009479| European Ancestry| 16,206 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.204 [0.1892, 0.2188] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012552 | PGS002213 (portability-ldpred2_neuroticism) |
PSS009253| European Ancestry| 2,941 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.184 [0.1487, 0.2188] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012553 | PGS002213 (portability-ldpred2_neuroticism) |
PSS008807| European Ancestry| 5,081 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.1899 [0.1632, 0.2163] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012554 | PGS002213 (portability-ldpred2_neuroticism) |
PSS008581| Greater Middle Eastern Ancestry| 632 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.1919 [0.1144, 0.2671] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012555 | PGS002213 (portability-ldpred2_neuroticism) |
PSS008359| South Asian Ancestry| 3,839 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.1475 [0.1163, 0.1783] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012557 | PGS002213 (portability-ldpred2_neuroticism) |
PSS007923| African Ancestry| 1,756 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.0769 [0.03, 0.1235] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012558 | PGS002213 (portability-ldpred2_neuroticism) |
PSS009027| African Ancestry| 2,505 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.0485 [0.0092, 0.0876] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012556 | PGS002213 (portability-ldpred2_neuroticism) |
PSS008136| East Asian Ancestry| 1,138 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Neuroticism score | — | — | Partial Correlation (partial-r): 0.1161 [0.0578, 0.1735] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM013107 | PGS002342 (mental_NEUROTICISM.BOLT-LMM) |
PSS009811| African Ancestry| 4,454 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0025 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013156 | PGS002342 (mental_NEUROTICISM.BOLT-LMM) |
PSS009812| East Asian Ancestry| 603 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0099 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013205 | PGS002342 (mental_NEUROTICISM.BOLT-LMM) |
PSS009813| European Ancestry| 34,276 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0309 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013254 | PGS002342 (mental_NEUROTICISM.BOLT-LMM) |
PSS009814| South Asian Ancestry| 4,984 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0238 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013395 | PGS002414 (mental_NEUROTICISM.P+T.0.0001) |
PSS009811| African Ancestry| 4,454 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013444 | PGS002414 (mental_NEUROTICISM.P+T.0.0001) |
PSS009812| East Asian Ancestry| 603 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0037 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013493 | PGS002414 (mental_NEUROTICISM.P+T.0.0001) |
PSS009813| European Ancestry| 34,276 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0064 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013542 | PGS002414 (mental_NEUROTICISM.P+T.0.0001) |
PSS009814| South Asian Ancestry| 4,984 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0028 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013591 | PGS002463 (mental_NEUROTICISM.P+T.0.001) |
PSS009811| African Ancestry| 4,454 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013689 | PGS002463 (mental_NEUROTICISM.P+T.0.001) |
PSS009813| European Ancestry| 34,276 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0077 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013738 | PGS002463 (mental_NEUROTICISM.P+T.0.001) |
PSS009814| South Asian Ancestry| 4,984 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0021 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013640 | PGS002463 (mental_NEUROTICISM.P+T.0.001) |
PSS009812| East Asian Ancestry| 603 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.006 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013934 | PGS002512 (mental_NEUROTICISM.P+T.0.01) |
PSS009814| South Asian Ancestry| 4,984 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0006 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013787 | PGS002512 (mental_NEUROTICISM.P+T.0.01) |
PSS009811| African Ancestry| 4,454 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013836 | PGS002512 (mental_NEUROTICISM.P+T.0.01) |
PSS009812| East Asian Ancestry| 603 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013885 | PGS002512 (mental_NEUROTICISM.P+T.0.01) |
PSS009813| European Ancestry| 34,276 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0043 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013983 | PGS002561 (mental_NEUROTICISM.P+T.1e-06) |
PSS009811| African Ancestry| 4,454 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0005 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014032 | PGS002561 (mental_NEUROTICISM.P+T.1e-06) |
PSS009812| East Asian Ancestry| 603 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0079 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014081 | PGS002561 (mental_NEUROTICISM.P+T.1e-06) |
PSS009813| European Ancestry| 34,276 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0029 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014130 | PGS002561 (mental_NEUROTICISM.P+T.1e-06) |
PSS009814| South Asian Ancestry| 4,984 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0029 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014179 | PGS002610 (mental_NEUROTICISM.P+T.5e-08) |
PSS009811| African Ancestry| 4,454 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0012 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014228 | PGS002610 (mental_NEUROTICISM.P+T.5e-08) |
PSS009812| East Asian Ancestry| 603 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0079 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014326 | PGS002610 (mental_NEUROTICISM.P+T.5e-08) |
PSS009814| South Asian Ancestry| 4,984 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0018 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014277 | PGS002610 (mental_NEUROTICISM.P+T.5e-08) |
PSS009813| European Ancestry| 34,276 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0017 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014375 | PGS002659 (mental_NEUROTICISM.PolyFun-pred) |
PSS009811| African Ancestry| 4,454 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0024 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See mental_NEUROTICISM.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014424 | PGS002659 (mental_NEUROTICISM.PolyFun-pred) |
PSS009812| East Asian Ancestry| 603 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0099 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See mental_NEUROTICISM.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014473 | PGS002659 (mental_NEUROTICISM.PolyFun-pred) |
PSS009813| European Ancestry| 34,276 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0296 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See mental_NEUROTICISM.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014522 | PGS002659 (mental_NEUROTICISM.PolyFun-pred) |
PSS009814| South Asian Ancestry| 4,984 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0145 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See mental_NEUROTICISM.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014669 | PGS002708 (mental_NEUROTICISM.SBayesR) |
PSS009813| European Ancestry| 34,276 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0284 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014571 | PGS002708 (mental_NEUROTICISM.SBayesR) |
PSS009811| African Ancestry| 4,454 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0039 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014620 | PGS002708 (mental_NEUROTICISM.SBayesR) |
PSS009812| East Asian Ancestry| 603 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0089 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014718 | PGS002708 (mental_NEUROTICISM.SBayesR) |
PSS009814| South Asian Ancestry| 4,984 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Neuroticism | — | — | Incremental R2 (full model vs. covariates alone): 0.0227 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM017493 | PGS003565 (cont-decay-neuroticism) |
PSS010932| European Ancestry| 16,317 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Neuroticism score | — | — | partial-R2: 0.05 | sex, age, deprivation index, PC1-16 | — |
| PPM017577 | PGS003565 (cont-decay-neuroticism) |
PSS010848| European Ancestry| 2,942 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Neuroticism score | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
| PPM017661 | PGS003565 (cont-decay-neuroticism) |
PSS010680| European Ancestry| 4,958 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Neuroticism score | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
| PPM017745 | PGS003565 (cont-decay-neuroticism) |
PSS010596| Greater Middle Eastern Ancestry| 633 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Neuroticism score | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
| PPM017829 | PGS003565 (cont-decay-neuroticism) |
PSS010260| European Ancestry| 1,892 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Neuroticism score | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
| PPM017913 | PGS003565 (cont-decay-neuroticism) |
PSS010512| South Asian Ancestry| 3,839 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Neuroticism score | — | — | partial-R2: 0.02 | sex, age, deprivation index, PC1-16 | — |
| PPM017997 | PGS003565 (cont-decay-neuroticism) |
PSS010428| East Asian Ancestry| 1,139 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Neuroticism score | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM018081 | PGS003565 (cont-decay-neuroticism) |
PSS010344| African Ancestry| 1,756 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Neuroticism score | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM018165 | PGS003565 (cont-decay-neuroticism) |
PSS010764| African Ancestry| 2,505 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Neuroticism score | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM020545 | PGS004430 (X20127.score) |
PSS011364| European Ancestry| 56,192 individuals |
PGP000561 | Jung H et al. Commun Biol (2024) |
Reported Trait: Neuroticism score | — | — | PGS R2 (no covariates): 0.15544 | — | — |
| PPM020770 | PGS004608 (neuroticism) |
PSS011400| Multi-ancestry (including European)| 486 individuals |
PGP000584 | Forthman KL et al. J Psychiatr Res (2023) |
Reported Trait: Repetitive negative thinking | — | — | R²: 0.0275 p-value (inferior to): 0.001 |
Age, sex, PCs of predictor features from behavioral and neuropsychological tasks | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS008136 | — | — | 1,138 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS010932 | — | — | 16,317 individuals, 47.0 % Male samples |
Mean = 56.7 years Sd = 7.9 years |
European | white British | UKB | — |
| PSS010680 | — | — | 4,958 individuals, 45.0 % Male samples |
Mean = 54.4 years Sd = 8.3 years |
European | Italian | UKB | — |
| PSS010428 | — | — | 1,139 individuals, 34.0 % Male samples |
Mean = 52.4 years Sd = 7.7 years |
East Asian | Chinese | UKB | — |
| PSS008807 | — | — | 5,081 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS007923 | — | — | 1,756 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS011400 | — | — | 321 individuals | — | European | — | T1000 | — |
| PSS011400 | — | — | 90 individuals | — | Native American | — | T1000 | — |
| PSS011400 | — | — | 31 individuals | — | African unspecified | — | T1000 | — |
| PSS011400 | — | — | 20 individuals | — | Hispanic or Latin American | — | T1000 | — |
| PSS011400 | — | — | 4 individuals | — | Asian unspecified | — | T1000 | — |
| PSS011400 | — | — | 20 individuals | — | Not reported | — | T1000 | — |
| PSS008581 | — | — | 632 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS010848 | — | — | 2,942 individuals, 38.0 % Male samples |
Mean = 54.8 years Sd = 7.4 years |
European | Polish | UKB | — |
| PSS009479 | — | — | 16,206 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS010596 | — | — | 633 individuals, 57.0 % Male samples |
Mean = 53.3 years Sd = 8.0 years |
Greater Middle Eastern (Middle Eastern, North African or Persian) | Iranian | UKB | — |
| PSS009811 | — | — | 4,454 individuals | — | African unspecified | — | UKB | — |
| PSS009812 | — | — | 603 individuals | — | East Asian | — | UKB | — |
| PSS009813 | — | — | 34,276 individuals | — | European | Non-British European | UKB | — |
| PSS009814 | — | — | 4,984 individuals | — | South Asian | — | UKB | — |
| PSS010344 | — | — | 1,756 individuals, 36.0 % Male samples |
Mean = 52.4 years Sd = 8.0 years |
African American or Afro-Caribbean | Caribbean | UKB | — |
| PSS011364 | — | — | 56,192 individuals | — | European | — | UKB | — |
| PSS009253 | — | — | 2,941 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS008359 | — | — | 3,839 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS010764 | — | — | 2,505 individuals, 46.0 % Male samples |
Mean = 52.1 years Sd = 8.0 years |
African unspecified | Nigerian | UKB | — |
| PSS010512 | — | — | 3,839 individuals, 55.0 % Male samples |
Mean = 52.9 years Sd = 8.4 years |
South Asian | Indian | UKB | — |
| PSS010260 | — | — | 1,892 individuals, 46.0 % Male samples |
Mean = 57.9 years Sd = 7.1 years |
European | Ashkenazi | UKB | — |
| PSS009027 | — | — | 2,505 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |