| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0007862 |
| Description | quantification of some aspect of reproductive behaviour such as age at first birth or number of children | Trait category |
Other measurement
|
| Mapped term | PMID:27798627 |
| Child trait(s) | 3 child traits |
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS001007 (GBE_INI2139) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Age at first sexual intercourse | age at first sexual intercourse measurement | 9,997 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001007/ScoringFiles/PGS001007.txt.gz |
| PGS001912 (portability-PLR_F_age_first_birth) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Age at first live birth | age at first birth measurement | 15,201 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001912/ScoringFiles/PGS001912.txt.gz |
| PGS001938 (portability-PLR_log_age_first_sex) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Age first had sexual intercourse | age at first sexual intercourse measurement | 64,164 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001938/ScoringFiles/PGS001938.txt.gz |
| PGS002127 (portability-ldpred2_F_age_first_birth) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Age at first live birth | age at first birth measurement | 848,784 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002127/ScoringFiles/PGS002127.txt.gz |
| PGS002156 (portability-ldpred2_log_age_first_sex) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Age first had sexual intercourse | age at first sexual intercourse measurement | 972,919 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002156/ScoringFiles/PGS002156.txt.gz |
| PGS002215 (portability-ldpred2_no_sex) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Age first had sexual intercourse | age at first sexual intercourse measurement | 633,660 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002215/ScoringFiles/PGS002215.txt.gz |
| PGS002309 (repro_NumberChildrenEverBorn_Pooled.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Number of children ever born | number of children ever born measurement | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002309/ScoringFiles/PGS002309.txt.gz |
| PGS002317 (repro_ChildLess.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Childless | reproductive behaviour measurement | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002317/ScoringFiles/PGS002317.txt.gz |
| PGS002381 (repro_NumberChildrenEverBorn_Pooled.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Number of children ever born | number of children ever born measurement | 1,639 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002381/ScoringFiles/PGS002381.txt.gz |
| PGS002389 (repro_ChildLess.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Childless | reproductive behaviour measurement | 1,578 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002389/ScoringFiles/PGS002389.txt.gz |
| PGS002430 (repro_NumberChildrenEverBorn_Pooled.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Number of children ever born | number of children ever born measurement | 11,512 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002430/ScoringFiles/PGS002430.txt.gz |
| PGS002438 (repro_ChildLess.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Childless | reproductive behaviour measurement | 10,891 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002438/ScoringFiles/PGS002438.txt.gz |
| PGS002479 (repro_NumberChildrenEverBorn_Pooled.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Number of children ever born | number of children ever born measurement | 89,453 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002479/ScoringFiles/PGS002479.txt.gz |
| PGS002487 (repro_ChildLess.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Childless | reproductive behaviour measurement | 86,054 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002487/ScoringFiles/PGS002487.txt.gz |
| PGS002528 (repro_NumberChildrenEverBorn_Pooled.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Number of children ever born | number of children ever born measurement | 66 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002528/ScoringFiles/PGS002528.txt.gz |
| PGS002536 (repro_ChildLess.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Childless | reproductive behaviour measurement | 53 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002536/ScoringFiles/PGS002536.txt.gz |
| PGS002577 (repro_NumberChildrenEverBorn_Pooled.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Number of children ever born | number of children ever born measurement | 21 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002577/ScoringFiles/PGS002577.txt.gz |
| PGS002585 (repro_ChildLess.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Childless | reproductive behaviour measurement | 12 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002585/ScoringFiles/PGS002585.txt.gz |
| PGS002626 (repro_NumberChildrenEverBorn_Pooled.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Number of children ever born | number of children ever born measurement | 208,715 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002626/ScoringFiles/PGS002626.txt.gz |
| PGS002634 (repro_ChildLess.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Childless | reproductive behaviour measurement | 176,147 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002634/ScoringFiles/PGS002634.txt.gz |
| PGS002675 (repro_NumberChildrenEverBorn_Pooled.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Number of children ever born | number of children ever born measurement | 981,889 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002675/ScoringFiles/PGS002675.txt.gz |
| PGS002683 (repro_ChildLess.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Childless | reproductive behaviour measurement | 954,898 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002683/ScoringFiles/PGS002683.txt.gz |
| PGS003505 (cont-decay-F_age_first_birth) |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Age at first live birth | age at first birth measurement | 979,739 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003505/ScoringFiles/PGS003505.txt.gz |
| PGS003520 (cont-decay-log_age_first_sex) |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Age first had sexual intercourse | age at first sexual intercourse measurement | 979,739 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003520/ScoringFiles/PGS003520.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM007798 | PGS001007 (GBE_INI2139) |
PSS004951| African Ancestry| 4,771 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | R²: 0.01638 [0.01026, 0.0225] Incremental R2 (full-covars): -0.00625 PGS R2 (no covariates): 0.0 [-0.00008, 0.00008] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007799 | PGS001007 (GBE_INI2139) |
PSS004952| East Asian Ancestry| 1,050 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | R²: 0.02181 [0.00812, 0.0355] Incremental R2 (full-covars): -0.00042 PGS R2 (no covariates): 0.00235 [-0.00223, 0.00693] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007800 | PGS001007 (GBE_INI2139) |
PSS004953| European Ancestry| 21,597 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | R²: 0.05384 [0.04839, 0.0593] Incremental R2 (full-covars): 0.02018 PGS R2 (no covariates): 0.02045 [0.01697, 0.02393] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007801 | PGS001007 (GBE_INI2139) |
PSS004954| South Asian Ancestry| 4,838 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | R²: 0.05962 [0.04945, 0.06979] Incremental R2 (full-covars): 0.00524 PGS R2 (no covariates): 0.00685 [0.00321, 0.01049] |
age, sex, UKB array type, Genotype PCs | — |
| PPM007802 | PGS001007 (GBE_INI2139) |
PSS004955| European Ancestry| 59,599 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | R²: 0.06968 [0.06597, 0.07339] Incremental R2 (full-covars): 0.02181 PGS R2 (no covariates): 0.0245 [0.02219, 0.0268] |
age, sex, UKB array type, Genotype PCs | — |
| PPM010179 | PGS001912 (portability-PLR_F_age_first_birth) |
PSS009371| European Ancestry| 3,989 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.1321 [0.1014, 0.1625] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010180 | PGS001912 (portability-PLR_F_age_first_birth) |
PSS009145| European Ancestry| 768 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.1462 [0.0753, 0.2156] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010181 | PGS001912 (portability-PLR_F_age_first_birth) |
PSS008699| European Ancestry| 1,149 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.0667 [0.0084, 0.1245] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010182 | PGS001912 (portability-PLR_F_age_first_birth) |
PSS008473| Greater Middle Eastern Ancestry| 157 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.0391 [-0.1289, 0.2048] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010183 | PGS001912 (portability-PLR_F_age_first_birth) |
PSS008251| South Asian Ancestry| 1,185 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.0506 [-0.0069, 0.1077] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010185 | PGS001912 (portability-PLR_F_age_first_birth) |
PSS007815| African Ancestry| 509 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): -0.0326 [-0.1209, 0.0561] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010186 | PGS001912 (portability-PLR_F_age_first_birth) |
PSS008919| African Ancestry| 746 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.0133 [-0.0595, 0.0859] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010184 | PGS001912 (portability-PLR_F_age_first_birth) |
PSS008029| East Asian Ancestry| 314 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): -0.0059 [-0.12, 0.1084] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010379 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS009437| European Ancestry| 17,510 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.2244 [0.2103, 0.2384] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010381 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS008765| European Ancestry| 5,704 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.162 [0.1366, 0.1872] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010382 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS008539| Greater Middle Eastern Ancestry| 781 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0725 [0.0014, 0.1428] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010383 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS008317| South Asian Ancestry| 3,788 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.1471 [0.1157, 0.1782] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010384 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS008094| East Asian Ancestry| 1,127 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0776 [0.0188, 0.1359] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010385 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS007881| African Ancestry| 1,805 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0537 [0.0073, 0.0999] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010386 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS008985| African Ancestry| 2,741 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0705 [0.033, 0.1078] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010380 | PGS001938 (portability-PLR_log_age_first_sex) |
PSS009211| European Ancestry| 3,425 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.1979 [0.1654, 0.2299] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011872 | PGS002127 (portability-ldpred2_F_age_first_birth) |
PSS009145| European Ancestry| 768 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.1972 [0.1273, 0.2652] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011871 | PGS002127 (portability-ldpred2_F_age_first_birth) |
PSS009371| European Ancestry| 3,989 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.1829 [0.1527, 0.2128] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011873 | PGS002127 (portability-ldpred2_F_age_first_birth) |
PSS008699| European Ancestry| 1,149 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.1779 [0.1208, 0.2338] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011874 | PGS002127 (portability-ldpred2_F_age_first_birth) |
PSS008473| Greater Middle Eastern Ancestry| 157 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.0501 [-0.118, 0.2154] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011875 | PGS002127 (portability-ldpred2_F_age_first_birth) |
PSS008251| South Asian Ancestry| 1,185 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.0625 [0.0051, 0.1195] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011876 | PGS002127 (portability-ldpred2_F_age_first_birth) |
PSS008029| East Asian Ancestry| 314 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): -0.0711 [-0.1838, 0.0434] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011877 | PGS002127 (portability-ldpred2_F_age_first_birth) |
PSS007815| African Ancestry| 509 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.0076 [-0.081, 0.0961] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011878 | PGS002127 (portability-ldpred2_F_age_first_birth) |
PSS008919| African Ancestry| 746 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age at first live birth | — | — | Partial Correlation (partial-r): 0.0199 [-0.0529, 0.0925] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012097 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS008765| European Ancestry| 5,704 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.1716 [0.1463, 0.1967] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012098 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS008539| Greater Middle Eastern Ancestry| 781 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0837 [0.0127, 0.1539] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012095 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS009437| European Ancestry| 17,510 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.2443 [0.2304, 0.2582] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012096 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS009211| European Ancestry| 3,425 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.2086 [0.1763, 0.2405] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012099 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS008317| South Asian Ancestry| 3,788 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.1587 [0.1274, 0.1897] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012100 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS008094| East Asian Ancestry| 1,127 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0976 [0.0389, 0.1556] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012101 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS007881| African Ancestry| 1,805 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0626 [0.0163, 0.1087] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012102 | PGS002156 (portability-ldpred2_log_age_first_sex) |
PSS008985| African Ancestry| 2,741 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0793 [0.0419, 0.1166] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012567 | PGS002215 (portability-ldpred2_no_sex) |
PSS009481| European Ancestry| 17,730 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0313 [0.0166, 0.046] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012570 | PGS002215 (portability-ldpred2_no_sex) |
PSS008583| Greater Middle Eastern Ancestry| 792 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): -0.0493 [-0.1194, 0.0213] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012571 | PGS002215 (portability-ldpred2_no_sex) |
PSS008361| South Asian Ancestry| 3,837 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): -0.0125 [-0.0442, 0.0192] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012572 | PGS002215 (portability-ldpred2_no_sex) |
PSS008138| East Asian Ancestry| 1,146 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.015 [-0.0434, 0.0734] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012573 | PGS002215 (portability-ldpred2_no_sex) |
PSS007925| African Ancestry| 1,855 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.012 [-0.0338, 0.0578] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012574 | PGS002215 (portability-ldpred2_no_sex) |
PSS009029| African Ancestry| 2,796 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): -0.0112 [-0.0484, 0.026] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012568 | PGS002215 (portability-ldpred2_no_sex) |
PSS009255| European Ancestry| 3,466 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.027 [-0.0064, 0.0603] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012569 | PGS002215 (portability-ldpred2_no_sex) |
PSS008809| European Ancestry| 5,786 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Age first had sexual intercourse | — | — | Partial Correlation (partial-r): 0.0161 [-0.0098, 0.0419] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM013123 | PGS002309 (repro_NumberChildrenEverBorn_Pooled.BOLT-LMM) |
PSS009680| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0011 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013172 | PGS002309 (repro_NumberChildrenEverBorn_Pooled.BOLT-LMM) |
PSS009681| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0082 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013221 | PGS002309 (repro_NumberChildrenEverBorn_Pooled.BOLT-LMM) |
PSS009682| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0032 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013074 | PGS002309 (repro_NumberChildrenEverBorn_Pooled.BOLT-LMM) |
PSS009679| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0005 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013082 | PGS002317 (repro_ChildLess.BOLT-LMM) |
PSS009711| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0026 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013131 | PGS002317 (repro_ChildLess.BOLT-LMM) |
PSS009712| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0066 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013180 | PGS002317 (repro_ChildLess.BOLT-LMM) |
PSS009713| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0058 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013229 | PGS002317 (repro_ChildLess.BOLT-LMM) |
PSS009714| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013362 | PGS002381 (repro_NumberChildrenEverBorn_Pooled.P+T.0.0001) |
PSS009679| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013411 | PGS002381 (repro_NumberChildrenEverBorn_Pooled.P+T.0.0001) |
PSS009680| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0013 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013460 | PGS002381 (repro_NumberChildrenEverBorn_Pooled.P+T.0.0001) |
PSS009681| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0003 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013509 | PGS002381 (repro_NumberChildrenEverBorn_Pooled.P+T.0.0001) |
PSS009682| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013370 | PGS002389 (repro_ChildLess.P+T.0.0001) |
PSS009711| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013419 | PGS002389 (repro_ChildLess.P+T.0.0001) |
PSS009712| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0032 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013468 | PGS002389 (repro_ChildLess.P+T.0.0001) |
PSS009713| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013517 | PGS002389 (repro_ChildLess.P+T.0.0001) |
PSS009714| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0008 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013558 | PGS002430 (repro_NumberChildrenEverBorn_Pooled.P+T.0.001) |
PSS009679| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: #Children | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013607 | PGS002430 (repro_NumberChildrenEverBorn_Pooled.P+T.0.001) |
PSS009680| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: #Children | — | — | Incremental R2 (full model vs. covariates alone): 0.0006 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013656 | PGS002430 (repro_NumberChildrenEverBorn_Pooled.P+T.0.001) |
PSS009681| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: #Children | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013705 | PGS002430 (repro_NumberChildrenEverBorn_Pooled.P+T.0.001) |
PSS009682| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: #Children | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013566 | PGS002438 (repro_ChildLess.P+T.0.001) |
PSS009711| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013664 | PGS002438 (repro_ChildLess.P+T.0.001) |
PSS009713| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013713 | PGS002438 (repro_ChildLess.P+T.0.001) |
PSS009714| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013615 | PGS002438 (repro_ChildLess.P+T.0.001) |
PSS009712| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0008 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013754 | PGS002479 (repro_NumberChildrenEverBorn_Pooled.P+T.0.01) |
PSS009679| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0009 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013852 | PGS002479 (repro_NumberChildrenEverBorn_Pooled.P+T.0.01) |
PSS009681| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0005 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013901 | PGS002479 (repro_NumberChildrenEverBorn_Pooled.P+T.0.01) |
PSS009682| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013803 | PGS002479 (repro_NumberChildrenEverBorn_Pooled.P+T.0.01) |
PSS009680| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0042 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013762 | PGS002487 (repro_ChildLess.P+T.0.01) |
PSS009711| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013811 | PGS002487 (repro_ChildLess.P+T.0.01) |
PSS009712| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0017 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013860 | PGS002487 (repro_ChildLess.P+T.0.01) |
PSS009713| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0005 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013909 | PGS002487 (repro_ChildLess.P+T.0.01) |
PSS009714| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0004 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013950 | PGS002528 (repro_NumberChildrenEverBorn_Pooled.P+T.1e-06) |
PSS009679| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013999 | PGS002528 (repro_NumberChildrenEverBorn_Pooled.P+T.1e-06) |
PSS009680| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0047 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014048 | PGS002528 (repro_NumberChildrenEverBorn_Pooled.P+T.1e-06) |
PSS009681| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014097 | PGS002528 (repro_NumberChildrenEverBorn_Pooled.P+T.1e-06) |
PSS009682| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0004 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013958 | PGS002536 (repro_ChildLess.P+T.1e-06) |
PSS009711| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014007 | PGS002536 (repro_ChildLess.P+T.1e-06) |
PSS009712| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014056 | PGS002536 (repro_ChildLess.P+T.1e-06) |
PSS009713| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014105 | PGS002536 (repro_ChildLess.P+T.1e-06) |
PSS009714| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0006 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014146 | PGS002577 (repro_NumberChildrenEverBorn_Pooled.P+T.5e-08) |
PSS009679| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0006 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014195 | PGS002577 (repro_NumberChildrenEverBorn_Pooled.P+T.5e-08) |
PSS009680| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0023 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014244 | PGS002577 (repro_NumberChildrenEverBorn_Pooled.P+T.5e-08) |
PSS009681| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0003 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014293 | PGS002577 (repro_NumberChildrenEverBorn_Pooled.P+T.5e-08) |
PSS009682| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0004 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014252 | PGS002585 (repro_ChildLess.P+T.5e-08) |
PSS009713| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014154 | PGS002585 (repro_ChildLess.P+T.5e-08) |
PSS009711| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014203 | PGS002585 (repro_ChildLess.P+T.5e-08) |
PSS009712| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0007 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014301 | PGS002585 (repro_ChildLess.P+T.5e-08) |
PSS009714| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014391 | PGS002626 (repro_NumberChildrenEverBorn_Pooled.PolyFun-pred) |
PSS009680| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0011 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See repro_NumberChildrenEverBorn_Pooled.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014440 | PGS002626 (repro_NumberChildrenEverBorn_Pooled.PolyFun-pred) |
PSS009681| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0082 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See repro_NumberChildrenEverBorn_Pooled.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014489 | PGS002626 (repro_NumberChildrenEverBorn_Pooled.PolyFun-pred) |
PSS009682| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.003 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See repro_NumberChildrenEverBorn_Pooled.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014342 | PGS002626 (repro_NumberChildrenEverBorn_Pooled.PolyFun-pred) |
PSS009679| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0005 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See repro_NumberChildrenEverBorn_Pooled.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014399 | PGS002634 (repro_ChildLess.PolyFun-pred) |
PSS009712| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0066 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See repro_ChildLess.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014448 | PGS002634 (repro_ChildLess.PolyFun-pred) |
PSS009713| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0045 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See repro_ChildLess.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014497 | PGS002634 (repro_ChildLess.PolyFun-pred) |
PSS009714| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0022 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See repro_ChildLess.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014350 | PGS002634 (repro_ChildLess.PolyFun-pred) |
PSS009711| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See repro_ChildLess.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014636 | PGS002675 (repro_NumberChildrenEverBorn_Pooled.SBayesR) |
PSS009681| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0075 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014538 | PGS002675 (repro_NumberChildrenEverBorn_Pooled.SBayesR) |
PSS009679| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0011 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014587 | PGS002675 (repro_NumberChildrenEverBorn_Pooled.SBayesR) |
PSS009680| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0017 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014685 | PGS002675 (repro_NumberChildrenEverBorn_Pooled.SBayesR) |
PSS009682| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Number of children ever born | — | — | Incremental R2 (full model vs. covariates alone): 0.0032 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014546 | PGS002683 (repro_ChildLess.SBayesR) |
PSS009711| African Ancestry| 6,193 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0023 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014595 | PGS002683 (repro_ChildLess.SBayesR) |
PSS009712| East Asian Ancestry| 909 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0043 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014644 | PGS002683 (repro_ChildLess.SBayesR) |
PSS009713| European Ancestry| 43,069 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0053 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014693 | PGS002683 (repro_ChildLess.SBayesR) |
PSS009714| South Asian Ancestry| 7,846 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Childless | — | — | Incremental R2 (full model vs. covariates alone): 0.0016 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM017601 | PGS003505 (cont-decay-F_age_first_birth) |
PSS010614| European Ancestry| 2,090 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age at first live birth | — | — | partial-R2: 0.04 | sex, age, deprivation index, PC1-16 | — |
| PPM017433 | PGS003505 (cont-decay-F_age_first_birth) |
PSS010866| European Ancestry| 7,313 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age at first live birth | — | — | partial-R2: 0.05 | sex, age, deprivation index, PC1-16 | — |
| PPM017517 | PGS003505 (cont-decay-F_age_first_birth) |
PSS010782| European Ancestry| 1,431 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age at first live birth | — | — | partial-R2: 0.04 | sex, age, deprivation index, PC1-16 | — |
| PPM017769 | PGS003505 (cont-decay-F_age_first_birth) |
PSS010194| European Ancestry| 857 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age at first live birth | — | — | partial-R2: 0.02 | sex, age, deprivation index, PC1-16 | — |
| PPM017853 | PGS003505 (cont-decay-F_age_first_birth) |
PSS010446| South Asian Ancestry| 2,150 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age at first live birth | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM017937 | PGS003505 (cont-decay-F_age_first_birth) |
PSS010362| East Asian Ancestry| 586 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age at first live birth | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM018021 | PGS003505 (cont-decay-F_age_first_birth) |
PSS010278| African Ancestry| 928 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age at first live birth | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM018105 | PGS003505 (cont-decay-F_age_first_birth) |
PSS010698| African Ancestry| 1,421 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age at first live birth | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM017685 | PGS003505 (cont-decay-F_age_first_birth) |
PSS010530| Greater Middle Eastern Ancestry| 292 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age at first live birth | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM017448 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010883| European Ancestry| 17,510 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.05 | sex, age, deprivation index, PC1-16 | — |
| PPM017532 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010799| European Ancestry| 3,426 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.04 | sex, age, deprivation index, PC1-16 | — |
| PPM017700 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010547| Greater Middle Eastern Ancestry| 781 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM017784 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010211| European Ancestry| 2,080 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
| PPM017868 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010463| South Asian Ancestry| 3,788 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.02 | sex, age, deprivation index, PC1-16 | — |
| PPM017952 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010379| East Asian Ancestry| 1,128 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
| PPM018036 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010295| African Ancestry| 1,805 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM018120 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010715| African Ancestry| 2,741 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
| PPM017616 | PGS003520 (cont-decay-log_age_first_sex) |
PSS010631| European Ancestry| 5,575 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: Age first had sexual intercourse | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS010782 | — | — | 1,431 individuals, 0.0 % Male samples |
Mean = 55.4 years Sd = 7.4 years |
European | Polish | UKB | — |
| PSS009029 | — | — | 2,796 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS010530 | — | — | 292 individuals, 0.0 % Male samples |
Mean = 53.0 years Sd = 8.1 years |
Greater Middle Eastern (Middle Eastern, North African or Persian) | Iranian | UKB | — |
| PSS007881 | — | — | 1,805 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS008138 | — | — | 1,146 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS010278 | — | — | 928 individuals, 0.0 % Male samples |
Mean = 53.9 years Sd = 7.9 years |
African American or Afro-Caribbean | Caribbean | UKB | — |
| PSS010799 | — | — | 3,426 individuals, 38.0 % Male samples |
Mean = 54.2 years Sd = 7.5 years |
European | Polish | UKB | — |
| PSS008919 | — | — | 746 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS010547 | — | — | 781 individuals, 60.0 % Male samples |
Mean = 52.6 years Sd = 7.9 years |
Greater Middle Eastern (Middle Eastern, North African or Persian) | Iranian | UKB | — |
| PSS008539 | — | — | 781 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS009437 | — | — | 17,510 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS008029 | — | — | 314 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS004951 | — | — | 4,771 individuals | — | African unspecified | — | UKB | — |
| PSS004952 | — | — | 1,050 individuals | — | East Asian | — | UKB | — |
| PSS004953 | — | — | 21,597 individuals | — | European | non-white British ancestry | UKB | — |
| PSS004954 | — | — | 4,838 individuals | — | South Asian | — | UKB | — |
| PSS004955 | — | — | 59,599 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS010295 | — | — | 1,805 individuals, 36.0 % Male samples |
Mean = 51.7 years Sd = 7.7 years |
African American or Afro-Caribbean | Caribbean | UKB | — |
| PSS008809 | — | — | 5,786 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS010698 | — | — | 1,421 individuals, 0.0 % Male samples |
Mean = 53.2 years Sd = 8.1 years |
African unspecified | Nigerian | UKB | — |
| PSS010446 | — | — | 2,150 individuals, 0.0 % Male samples |
Mean = 53.4 years Sd = 8.0 years |
South Asian | Indian | UKB | — |
| PSS007925 | — | — | 1,855 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS010194 | — | — | 857 individuals, 0.0 % Male samples |
Mean = 58.5 years Sd = 6.8 years |
European | Ashkenazi | UKB | — |
| PSS008699 | — | — | 1,149 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS009211 | — | — | 3,425 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS008317 | — | — | 3,788 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS010715 | — | — | 2,741 individuals, 48.0 % Male samples |
Mean = 51.1 years Sd = 7.7 years |
African unspecified | Nigerian | UKB | — |
| PSS010463 | — | — | 3,788 individuals, 58.0 % Male samples |
Mean = 52.4 years Sd = 8.3 years |
South Asian | Indian | UKB | — |
| PSS007815 | — | — | 509 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS008583 | — | — | 792 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS009481 | — | — | 17,730 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS009680 | — | — | 909 individuals | — | East Asian | — | UKB | — |
| PSS009681 | — | — | 43,069 individuals | — | European | Non-British European | UKB | — |
| PSS009682 | — | — | 7,846 individuals | — | South Asian | — | UKB | — |
| PSS009679 | — | — | 6,193 individuals | — | African unspecified | — | UKB | — |
| PSS010211 | — | — | 2,080 individuals, 45.0 % Male samples |
Mean = 58.0 years Sd = 7.1 years |
European | Ashkenazi | UKB | — |
| PSS010866 | — | — | 7,313 individuals, 0.0 % Male samples |
Mean = 57.6 years Sd = 7.5 years |
European | white British | UKB | — |
| PSS008473 | — | — | 157 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS008985 | — | — | 2,741 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS009371 | — | — | 3,989 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS010614 | — | — | 2,090 individuals, 0.0 % Male samples |
Mean = 55.5 years Sd = 8.1 years |
European | Italian | UKB | — |
| PSS008094 | — | — | 1,127 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS010362 | — | — | 586 individuals, 0.0 % Male samples |
Mean = 53.5 years Sd = 7.5 years |
East Asian | Chinese | UKB | — |
| PSS009255 | — | — | 3,466 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS009711 | — | — | 6,193 individuals | — | African unspecified | — | UKB | — |
| PSS008361 | — | — | 3,837 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS009712 | — | — | 909 individuals | — | East Asian | — | UKB | — |
| PSS009713 | — | — | 43,069 individuals | — | European | Non-British European | UKB | — |
| PSS009714 | — | — | 7,846 individuals | — | South Asian | — | UKB | — |
| PSS010883 | — | — | 17,510 individuals, 46.0 % Male samples |
Mean = 56.5 years Sd = 7.9 years |
European | white British | UKB | — |
| PSS010631 | — | — | 5,575 individuals, 45.0 % Male samples |
Mean = 54.2 years Sd = 8.3 years |
European | Italian | UKB | — |
| PSS010379 | — | — | 1,128 individuals, 36.0 % Male samples |
Mean = 51.7 years Sd = 7.7 years |
East Asian | Chinese | UKB | — |
| PSS009145 | — | — | 768 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS008251 | — | — | 1,185 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS008765 | — | — | 5,704 individuals | — | European | Italy (South Europe) | UKB | — |