Trait: emotional symptom measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007803
Description quantification of some aspect of emotional problem symptoms, such as their existence and severity, u... sually via a standardised questionnaire such as the emotional symptoms subscale of the Strengths and Difficulties Questionnaire or interview with a qualified mental health professionalShow more
Trait category
Other measurement
Child trait(s) 5 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "emotional symptom measurement" and any child terms of this trait in the EFO hierarchy by default.
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Polygenic Score ID & Name
PGS Publication ID (PGP)
Reported Trait
Mapped Trait(s) (Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS001016
(GBE_BIN1950)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Sensitivity / hurt feelingsfeeling emotionally hurt measurement7,922
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001016/ScoringFiles/PGS001016.txt.gz
PGS001017
(GBE_BIN2010)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Suffer from 'nerves'feeling nervous measurement3,348
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001017/ScoringFiles/PGS001017.txt.gz
PGS001018
(GBE_BIN_FC10006160)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Attending social / leisure activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity)social interaction measurement2,912
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001018/ScoringFiles/PGS001018.txt.gz
PGS001019
(GBE_BIN_FC20006160)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Attending social / leisure activities (regular attendance at a gym or sports club)social interaction measurement11,361
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001019/ScoringFiles/PGS001019.txt.gz
PGS001020
(GBE_BIN_FC50006160)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Attending social / leisure activities (regular attendance at an adult education class)social interaction measurement220
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001020/ScoringFiles/PGS001020.txt.gz
PGS001021
(GBE_BIN1980)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Feelings of worry or anxietyworry measurement,
anxiety measurement		9,747
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001021/ScoringFiles/PGS001021.txt.gz
PGS001022
(GBE_BIN2000)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Worry too long after an embarrassing experienceworry measurement7,714
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001022/ScoringFiles/PGS001022.txt.gz
PGS001396
(GBE_QT_FC1002060)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Frequency of unenthusiasm / disinterest in last 2 weeksemotional symptom measurement2,431
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001396/ScoringFiles/PGS001396.txt.gz
PGS001920
(portability-PLR_foreboding_feelings)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Recent feelings of forebodingworry measurement2,894
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001920/ScoringFiles/PGS001920.txt.gz
PGS002136
(portability-ldpred2_foreboding_feelings)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Recent feelings of forebodingworry measurement733,839
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002136/ScoringFiles/PGS002136.txt.gz
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
Evaluated Score
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM007245PGS001396
(GBE_QT_FC1002060)
PSS007581|
African Ancestry|
5,837 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Freq. of unenthusiasm / disinterest in last 2 weeks——R²: 0.00813 [0.00379, 0.01248]
Incremental R2 (full-covars): -0.00053
PGS R2 (no covariates): 0.00015 [-0.00044, 0.00073]		age, sex, UKB array type, Genotype PCs—
PPM007246PGS001396
(GBE_QT_FC1002060)
PSS007582|
East Asian Ancestry|
1,496 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Freq. of unenthusiasm / disinterest in last 2 weeks——R²: 0.02489 [0.01031, 0.03947]
Incremental R2 (full-covars): -0.00242
PGS R2 (no covariates): 0.0007 [-0.00181, 0.00321]		age, sex, UKB array type, Genotype PCs—
PPM007247PGS001396
(GBE_QT_FC1002060)
PSS007583|
European Ancestry|
23,872 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Freq. of unenthusiasm / disinterest in last 2 weeks——R²: 0.023 [0.01932, 0.02668]
Incremental R2 (full-covars): 0.00212
PGS R2 (no covariates): 0.00251 [0.00127, 0.00376]		age, sex, UKB array type, Genotype PCs—
PPM007248PGS001396
(GBE_QT_FC1002060)
PSS007584|
South Asian Ancestry|
6,548 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Freq. of unenthusiasm / disinterest in last 2 weeks——R²: 0.00941 [0.00515, 0.01366]
Incremental R2 (full-covars): -0.00072
PGS R2 (no covariates): 0.0 [-0.00005, 0.00005]		age, sex, UKB array type, Genotype PCs—
PPM007249PGS001396
(GBE_QT_FC1002060)
PSS007585|
European Ancestry|
65,413 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Freq. of unenthusiasm / disinterest in last 2 weeks——R²: 0.01367 [0.01193, 0.01541]
Incremental R2 (full-covars): 0.00193
PGS R2 (no covariates): 0.00206 [0.00138, 0.00274]		age, sex, UKB array type, Genotype PCs—
PPM007843PGS001016
(GBE_BIN1950)
PSS003637|
African Ancestry|
6,118 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sensitivity / hurt feelings—AUROC: 0.59163 [0.57735, 0.60591]R²: 0.0326
Incremental AUROC (full-covars): -0.01552
PGS R2 (no covariates): 7e-05
PGS AUROC (no covariates): 0.49648 [0.48187, 0.5111]		age, sex, UKB array type, Genotype PCsFull Model & PGS R2 is estimated using Nagelkerke's method
PPM007844PGS001016
(GBE_BIN1950)
PSS003638|
East Asian Ancestry|
1,534 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sensitivity / hurt feelings—AUROC: 0.61857 [0.59048, 0.64665]R²: 0.06515
Incremental AUROC (full-covars): 0.00123
PGS R2 (no covariates): 0.00285
PGS AUROC (no covariates): 0.52442 [0.49546, 0.55337]		age, sex, UKB array type, Genotype PCsFull Model & PGS R2 is estimated using Nagelkerke's method
PPM007845PGS001016
(GBE_BIN1950)
PSS003639|
European Ancestry|
24,064 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sensitivity / hurt feelings—AUROC: 0.60838 [0.60128, 0.61549]R²: 0.04732
Incremental AUROC (full-covars): 0.01171
PGS R2 (no covariates): 0.00998
PGS AUROC (no covariates): 0.54753 [0.54024, 0.55481]		age, sex, UKB array type, Genotype PCsFull Model & PGS R2 is estimated using Nagelkerke's method
PPM007846PGS001016
(GBE_BIN1950)
PSS003640|
South Asian Ancestry|
7,159 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sensitivity / hurt feelings—AUROC: 0.60244 [0.58913, 0.61576]R²: 0.03988
Incremental AUROC (full-covars): 0.00657
PGS R2 (no covariates): 0.00436
PGS AUROC (no covariates): 0.53424 [0.5206, 0.54787]		age, sex, UKB array type, Genotype PCsFull Model & PGS R2 is estimated using Nagelkerke's method
PPM007847PGS001016
(GBE_BIN1950)
PSS003641|
European Ancestry|
65,709 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Sensitivity / hurt feelings—AUROC: 0.62016 [0.61586, 0.62446]R²: 0.0571
Incremental AUROC (full-covars): 0.01553
PGS R2 (no covariates): 0.00873
PGS AUROC (no covariates): 0.54593 [0.5415, 0.55036]		age, sex, UKB array type, Genotype PCsFull Model & PGS R2 is estimated using Nagelkerke's method
PPM007848PGS001017
(GBE_BIN2010)
PSS003652|
African Ancestry|
5,987 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Suffer from 'nerves'—AUROC: 0.51358 [0.49307, 0.53409]R²: 0.00091
Incremental AUROC (full-covars): -0.01868
PGS R2 (no covariates): 0.0002
PGS AUROC (no covariates): 0.49271 [0.47201, 0.51341]		age, sex, UKB array type, Genotype PCsFull Model & PGS R2 is estimated using Nagelkerke's method
PPM007849PGS001017
(GBE_BIN2010)
PSS003653|
East Asian Ancestry|
1,473 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Suffer from 'nerves'—AUROC: 0.56758 [0.53117, 0.604]R²: 0.01953
Incremental AUROC (full-covars): -0.01086
PGS R2 (no covariates): 0.00022
PGS AUROC (no covariates): 0.51056 [0.47283, 0.54828]		age, sex, UKB array type, Genotype PCsFull Model & PGS R2 is estimated using Nagelkerke's method
PPM007850PGS001017
(GBE_BIN2010)
PSS003654|
European Ancestry|
23,768 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Suffer from 'nerves'—AUROC: 0.56488 [0.556, 0.57377]R²: 0.01344
Incremental AUROC (full-covars): 0.00629
PGS R2 (no covariates): 0.00341
PGS AUROC (no covariates): 0.53323 [0.52425, 0.54221]		age, sex, UKB array type, Genotype PCsFull Model & PGS R2 is estimated using Nagelkerke's method
PPM007851PGS001017
(GBE_BIN2010)
PSS003655|
South Asian Ancestry|
6,958 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Suffer from 'nerves'—AUROC: 0.58706 [0.57106, 0.60305]R²: 0.02294
Incremental AUROC (full-covars): -0.00056
PGS R2 (no covariates): 0.00138
PGS AUROC (no covariates): 0.52168 [0.50524, 0.53812]		age, sex, UKB array type, Genotype PCsFull Model & PGS R2 is estimated using Nagelkerke's method
PPM007852PGS001017
(GBE_BIN2010)
PSS003656|
European Ancestry|
65,185 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Suffer from 'nerves'—AUROC: 0.55991 [0.55463, 0.56519]R²: 0.01151
Incremental AUROC (full-covars): 0.01586
PGS R2 (no covariates): 0.00563
PGS AUROC (no covariates): 0.5416 [0.53628, 0.54693]		age, sex, UKB array type, Genotype PCsFull Model & PGS R2 is estimated using Nagelkerke's method
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS003637——
[
  • 2,629 cases
  • , 3,489 controls
]
—African unspecified—UKB—
PSS003638——
[
  • 681 cases
  • , 853 controls
]
—East Asian—UKB—
PSS003639——
[
  • 13,147 cases
  • , 10,917 controls
]
—Europeannon-white British ancestryUKB—
PSS003640——
[
  • 4,355 cases
  • , 2,804 controls
]
—South Asian—UKB—
PSS003641——
[
  • 37,128 cases
  • , 28,581 controls
]
—Europeanwhite British ancestryUKBTesting cohort (heldout set)
PSS003642——
[
  • 2,702 cases
  • , 3,402 controls
]
—African unspecified—UKB—
PSS003643——
[
  • 746 cases
  • , 798 controls
]
—East Asian—UKB—
PSS003644——
[
  • 13,973 cases
  • , 10,197 controls
]
—Europeannon-white British ancestryUKB—
PSS003645——
[
  • 3,970 cases
  • , 3,200 controls
]
—South Asian—UKB—
PSS003646——
[
  • 37,860 cases
  • , 27,938 controls
]
—Europeanwhite British ancestryUKBTesting cohort (heldout set)
PSS003647——
[
  • 2,619 cases
  • , 3,470 controls
]
—African unspecified—UKB—
PSS003648——
[
  • 605 cases
  • , 925 controls
]
—East Asian—UKB—
PSS003649——
[
  • 11,647 cases
  • , 12,202 controls
]
—Europeannon-white British ancestryUKB—
PSS003650——
[
  • 3,557 cases
  • , 3,436 controls
]
—South Asian—UKB—
PSS003651——
[
  • 31,708 cases
  • , 33,200 controls
]
—Europeanwhite British ancestryUKBTesting cohort (heldout set)
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