| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0000701 |
| Description | Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs. [NCIT: C3371] | Trait category |
Other disease
|
| Synonyms |
16 synonyms
|
| Mapped terms |
18 mapped terms
|
| Child trait(s) |
21 child traits
|
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS000119 (BCC32) |
PGP000055 | Fritsche LG et al. PLoS Genet (2019) |
Basal cell carcinoma | basal cell carcinoma | 32 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000119/ScoringFiles/PGS000119.txt.gz |
| PGS000339 (PRS22_CM) |
PGP000106 | Law MH et al. Hum Mol Genet (2020) |
Cutaneous melanoma | cutaneous melanoma | 22 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000339/ScoringFiles/PGS000339.txt.gz | |
| PGS000341 (GRS33_SSc) |
PGP000110 | Bossini-Castillo L et al. Ann Rheum Dis (2020) |
Systemic sclerosis | systemic scleroderma | 33 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000341/ScoringFiles/PGS000341.txt.gz | |
| PGS000398 (PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Skin cancer | skin carcinoma | 1,103,220 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000398/ScoringFiles/PGS000398.txt.gz | |
| PGS000399 (PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Skin cancer | skin carcinoma | 6 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000399/ScoringFiles/PGS000399.txt.gz | |
| PGS000400 (PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Skin cancer | skin carcinoma | 95 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000400/ScoringFiles/PGS000400.txt.gz | |
| PGS000401 (PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Skin cancer | skin carcinoma | 1,111,490 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000401/ScoringFiles/PGS000401.txt.gz | |
| PGS000402 (PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Skin cancer | skin carcinoma | 389 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000402/ScoringFiles/PGS000402.txt.gz | |
| PGS000403 (PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Skin cancer | skin carcinoma | 16,316 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000403/ScoringFiles/PGS000403.txt.gz | |
| PGS000404 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Skin cancer | skin carcinoma | 80 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000404/ScoringFiles/PGS000404.txt.gz | |
| PGS000405 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Skin cancer | skin carcinoma | 1,119,238 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000405/ScoringFiles/PGS000405.txt.gz | |
| PGS000406 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Skin cancer | skin carcinoma | 292 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000406/ScoringFiles/PGS000406.txt.gz | |
| PGS000407 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Skin cancer | skin carcinoma | 3,166 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000407/ScoringFiles/PGS000407.txt.gz | |
| PGS000433 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 108 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000433/ScoringFiles/PGS000433.txt.gz | |
| PGS000434 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 1,111,490 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000434/ScoringFiles/PGS000434.txt.gz | |
| PGS000435 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 446 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000435/ScoringFiles/PGS000435.txt.gz | |
| PGS000436 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 16,626 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000436/ScoringFiles/PGS000436.txt.gz | |
| PGS000437 (PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 63 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000437/ScoringFiles/PGS000437.txt.gz | |
| PGS000438 (PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 1,111,490 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000438/ScoringFiles/PGS000438.txt.gz | |
| PGS000439 (PRSWEB_PHECODE172.2_C44_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 467 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000439/ScoringFiles/PGS000439.txt.gz | |
| PGS000440 (PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 2,111 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000440/ScoringFiles/PGS000440.txt.gz | |
| PGS000441 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 77 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000441/ScoringFiles/PGS000441.txt.gz | |
| PGS000442 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 1,119,238 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000442/ScoringFiles/PGS000442.txt.gz | |
| PGS000443 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 177 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000443/ScoringFiles/PGS000443.txt.gz | |
| PGS000444 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Other non-epithelial skin cancer | skin cancer | 7,231 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000444/ScoringFiles/PGS000444.txt.gz | |
| PGS000445 (PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 19 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000445/ScoringFiles/PGS000445.txt.gz | |
| PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 1,111,490 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000446/ScoringFiles/PGS000446.txt.gz | |
| PGS000447 (PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 72 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000447/ScoringFiles/PGS000447.txt.gz | |
| PGS000448 (PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 183 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000448/ScoringFiles/PGS000448.txt.gz | |
| PGS000449 (PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 1,073,162 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000449/ScoringFiles/PGS000449.txt.gz | |
| PGS000450 (PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 8 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000450/ScoringFiles/PGS000450.txt.gz | |
| PGS000451 (PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 2,231 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000451/ScoringFiles/PGS000451.txt.gz | |
| PGS000452 (PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 28 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000452/ScoringFiles/PGS000452.txt.gz | |
| PGS000453 (PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 28 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000453/ScoringFiles/PGS000453.txt.gz | |
| PGS000454 (PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 27 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000454/ScoringFiles/PGS000454.txt.gz | |
| PGS000455 (PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 28 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000455/ScoringFiles/PGS000455.txt.gz | |
| PGS000456 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 30 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000456/ScoringFiles/PGS000456.txt.gz | |
| PGS000457 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 30 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000457/ScoringFiles/PGS000457.txt.gz | |
| PGS000458 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 23 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000458/ScoringFiles/PGS000458.txt.gz | |
| PGS000459 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Basal cell carcinoma | basal cell carcinoma | 24 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000459/ScoringFiles/PGS000459.txt.gz | |
| PGS000469 (PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Carcinoma in situ of skin | skin carcinoma in situ | 1,119,238 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000469/ScoringFiles/PGS000469.txt.gz | |
| PGS000470 (PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Carcinoma in situ of skin | skin carcinoma in situ | 5 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000470/ScoringFiles/PGS000470.txt.gz | |
| PGS000471 (PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Carcinoma in situ of skin | skin carcinoma in situ | 7 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000471/ScoringFiles/PGS000471.txt.gz | |
| PGS000730 (PRS_BCC) |
PGP000138 | Fontanillas P et al. Nat Commun (2021) |
Basal cell carcinoma | basal cell carcinoma | 47 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000730/ScoringFiles/PGS000730.txt.gz |
| PGS000738 (CONFIRMED_PGS) |
PGP000145 | Roberts GHL et al. Am J Hum Genet (2019) |
Vitiligo | Vitiligo | 48 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000738/ScoringFiles/PGS000738.txt.gz |
| PGS000760 (VIT) |
PGP000164 | Khan Z et al. Nat Commun (2021) |
Vitiligo | Vitiligo | 42 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000760/ScoringFiles/PGS000760.txt.gz | |
| PGS000766 (PRS56_CM) |
PGP000172 | Bakshi A et al. J Natl Cancer Inst (2021) |
Cutaneous melanoma | cutaneous melanoma | 56 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000766/ScoringFiles/PGS000766.txt.gz |
| PGS000927 (GBE_HC1158) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Other dermatitis (time-to-event) | dermatitis | 242 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000927/ScoringFiles/PGS000927.txt.gz |
| PGS000944 (GBE_HC261) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Eczema, dermatitis | Eczematoid dermatitis, dermatitis |
598 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000944/ScoringFiles/PGS000944.txt.gz |
| PGS000963 (GBE_HC1184) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Follicular cysts of skin and subcutaneous tissue (time-to-event) | Follicular Cyst | 264 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000963/ScoringFiles/PGS000963.txt.gz |
| PGS001011 (GBE_HC534) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Viral warts (time-to-event) | common wart | 5 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001011/ScoringFiles/PGS001011.txt.gz |
| PGS001040 (GBE_cancer1060) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Non melanoma skin cancer | non-melanoma skin carcinoma | 1,610 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001040/ScoringFiles/PGS001040.txt.gz |
| PGS001041 (GBE_cancer1003) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Skin cancer | skin carcinoma | 1,298 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001041/ScoringFiles/PGS001041.txt.gz |
| PGS001131 (GBE_HC530) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Zoster [herpes zoster] (time-to-event) | Herpes Zoster | 82 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001131/ScoringFiles/PGS001131.txt.gz |
| PGS001140 (GBE_HC1190) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Seborrheic keratosis (time-to-event) | seborrheic keratosis | 1,368 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001140/ScoringFiles/PGS001140.txt.gz |
| PGS001257 (GBE_INI1737) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Childhood sunburn | sunburn | 519 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001257/ScoringFiles/PGS001257.txt.gz |
| PGS001312 (GBE_HC38) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Psoriasis | psoriasis | 204 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001312/ScoringFiles/PGS001312.txt.gz |
| PGS001313 (GBE_HC1159) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Psoriasis (time-to-event) | psoriasis | 578 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001313/ScoringFiles/PGS001313.txt.gz |
| PGS001536 (GBE_HC1188) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Vitiligo (time-to-event) | Vitiligo | 77 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001536/ScoringFiles/PGS001536.txt.gz |
| PGS001773 (PRS_atopicDermatitis) |
PGP000253 | Simard M et al. J Allergy Clin Immunol (2020) |
Moderate-to-severe atopic dermatitis | atopic eczema | 25 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001773/ScoringFiles/PGS001773.txt.gz |
| PGS001803 (portability-PLR_172) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Skin cancer | skin carcinoma | 4,371 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001803/ScoringFiles/PGS001803.txt.gz |
| PGS001869 (portability-PLR_681) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Superficial cellulitis and abscess | cellulitis | 131 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001869/ScoringFiles/PGS001869.txt.gz |
| PGS001871 (portability-PLR_696.4) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Psoriasis | psoriasis | 264 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001871/ScoringFiles/PGS001871.txt.gz |
| PGS001872 (portability-PLR_697) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Sarcoidosis | skin sarcoidosis | 79 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001872/ScoringFiles/PGS001872.txt.gz |
| PGS001874 (portability-PLR_706.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Sebaceous cyst | Epidermal Inclusion Cyst | 563 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001874/ScoringFiles/PGS001874.txt.gz |
| PGS002014 (portability-ldpred2_172) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Skin cancer | skin carcinoma | 534,399 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002014/ScoringFiles/PGS002014.txt.gz |
| PGS002081 (portability-ldpred2_681) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Superficial cellulitis and abscess | cellulitis | 640,921 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002081/ScoringFiles/PGS002081.txt.gz |
| PGS002083 (portability-ldpred2_696.4) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Psoriasis | psoriasis | 71,744 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002083/ScoringFiles/PGS002083.txt.gz |
| PGS002084 (portability-ldpred2_697) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Sarcoidosis | skin sarcoidosis | 403,417 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002084/ScoringFiles/PGS002084.txt.gz |
| PGS002085 (portability-ldpred2_702.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Seborrheic keratosis | seborrheic keratosis | 481,233 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002085/ScoringFiles/PGS002085.txt.gz |
| PGS002087 (portability-ldpred2_706.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Sebaceous cyst | Epidermal Inclusion Cyst | 206,669 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002087/ScoringFiles/PGS002087.txt.gz |
| PGS002293 (PRS62_psoriasis) |
PGP000323 | Shen M et al. J Am Acad Dermatol (2022) |
Psoriasis | psoriasis | 62 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002293/ScoringFiles/PGS002293.txt.gz |
| PGS002320 (disease_DERMATOLOGY.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Dermatologic diseases | skin disease | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002320/ScoringFiles/PGS002320.txt.gz |
| PGS002344 (disease_PSORIASIS.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Psoriasis | psoriasis | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002344/ScoringFiles/PGS002344.txt.gz |
| PGS002392 (disease_DERMATOLOGY.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Dermatologic diseases | skin disease | 3,539 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002392/ScoringFiles/PGS002392.txt.gz |
| PGS002416 (disease_PSORIASIS.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Psoriasis | psoriasis | 6,879 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002416/ScoringFiles/PGS002416.txt.gz |
| PGS002441 (disease_DERMATOLOGY.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Dermatologic diseases | skin disease | 14,624 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002441/ScoringFiles/PGS002441.txt.gz |
| PGS002465 (disease_PSORIASIS.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Psoriasis | psoriasis | 21,483 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002465/ScoringFiles/PGS002465.txt.gz |
| PGS002490 (disease_DERMATOLOGY.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Dermatologic diseases | skin disease | 88,324 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002490/ScoringFiles/PGS002490.txt.gz |
| PGS002514 (disease_PSORIASIS.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Psoriasis | psoriasis | 96,453 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002514/ScoringFiles/PGS002514.txt.gz |
| PGS002539 (disease_DERMATOLOGY.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Dermatologic diseases | skin disease | 540 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002539/ScoringFiles/PGS002539.txt.gz |
| PGS002563 (disease_PSORIASIS.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Psoriasis | psoriasis | 1,348 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002563/ScoringFiles/PGS002563.txt.gz |
| PGS002588 (disease_DERMATOLOGY.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Dermatologic diseases | skin disease | 240 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002588/ScoringFiles/PGS002588.txt.gz |
| PGS002612 (disease_PSORIASIS.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Psoriasis | psoriasis | 643 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002612/ScoringFiles/PGS002612.txt.gz |
| PGS002637 (disease_DERMATOLOGY.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Dermatologic diseases | skin disease | 164,178 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002637/ScoringFiles/PGS002637.txt.gz |
| PGS002661 (disease_PSORIASIS.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Psoriasis | psoriasis | 283,128 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002661/ScoringFiles/PGS002661.txt.gz |
| PGS002686 (disease_DERMATOLOGY.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Dermatologic diseases | skin disease | 815,851 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002686/ScoringFiles/PGS002686.txt.gz |
| PGS002710 (disease_PSORIASIS.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Psoriasis | psoriasis | 566,839 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002710/ScoringFiles/PGS002710.txt.gz |
| PGS002755 (Atopic_dermatitis_prscs) |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Atopic dermatitis | atopic eczema | 1,090,702 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002755/ScoringFiles/PGS002755.txt.gz |
| PGS003382 (best_SKCM) |
PGP000413 | Namba S et al. Cancer Res (2022) |
Skin cutaneous melanoma | cutaneous melanoma | 672 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003382/ScoringFiles/PGS003382.txt.gz |
| PGS003416 (MTAGPRS) |
PGP000429 | Seviiri M et al. Nat Commun (2022) |
Basal cell carcinoma (MTAG) | basal cell carcinoma | 462 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003416/ScoringFiles/PGS003416.txt.gz |
| PGS003417 (UKBPRS) |
PGP000429 | Seviiri M et al. Nat Commun (2022) |
Basal cell carcinoma | basal cell carcinoma | 273 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003417/ScoringFiles/PGS003417.txt.gz |
| PGS003459 (PRS_CO) |
PGP000451 | Al-Janabi A et al. J Invest Dermatol (2023) |
Atopic eczema or atopic disease | atopic eczema, allergic disease |
170 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003459/ScoringFiles/PGS003459.txt.gz |
| PGS003486 (PRS_AE) |
PGP000451 | Al-Janabi A et al. J Invest Dermatol (2023) |
Atopic eczema | atopic eczema | 71 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003486/ScoringFiles/PGS003486.txt.gz |
| PGS003745 (PRS57_SM) |
PGP000470 | Xin J et al. EBioMedicine (2023) |
Skin Melanoma | cutaneous melanoma | 57 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003745/ScoringFiles/PGS003745.txt.gz | |
| PGS004247 (PRS65_melanoma) |
PGP000542 | Kim ES et al. NPJ Precis Oncol (2023) |
Melanoma | cutaneous melanoma | 65 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004247/ScoringFiles/PGS004247.txt.gz |
| PGS004260 (GenoBoost_psoriasis_0) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Psoriasis | psoriasis | 900 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004260/ScoringFiles/PGS004260.txt.gz |
| PGS004261 (GenoBoost_psoriasis_1) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Psoriasis | psoriasis | 800 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004261/ScoringFiles/PGS004261.txt.gz |
| PGS004262 (GenoBoost_psoriasis_2) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Psoriasis | psoriasis | 200 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004262/ScoringFiles/PGS004262.txt.gz |
| PGS004263 (GenoBoost_psoriasis_3) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Psoriasis | psoriasis | 800 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004263/ScoringFiles/PGS004263.txt.gz |
| PGS004264 (GenoBoost_psoriasis_4) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Psoriasis | psoriasis | 110 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004264/ScoringFiles/PGS004264.txt.gz |
| PGS004315 (GRS-ALL) |
PGP000547 | Bui A et al. Front Genet (2023) |
Psoriasis | psoriasis | 88 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004315/ScoringFiles/PGS004315.txt.gz |
| PGS004316 (GRS-HLA) |
PGP000547 | Bui A et al. Front Genet (2023) |
Psoriasis | psoriasis | 11 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004316/ScoringFiles/PGS004316.txt.gz |
| PGS004317 (GRS-noHLA) |
PGP000547 | Bui A et al. Front Genet (2023) |
Psoriasis | psoriasis | 77 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004317/ScoringFiles/PGS004317.txt.gz |
| PGS004324 (PRS6314_PN) |
PGP000558 | Vasavda C et al. J Invest Dermatol (2023) |
Prurigo nodularis | prurigo nodularis | 6,314 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004324/ScoringFiles/PGS004324.txt.gz | |
| PGS004587 (PRS23_AD) |
PGP000566 | Gu X et al. Ecotoxicol Environ Saf (2023) |
Atopic dermatitis | atopic eczema | 23 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004587/ScoringFiles/PGS004587.txt.gz |
| PGS004592 (PRS_KC) |
PGP000571 | Liyanage UE et al. J Eur Acad Dermatol Venereol (2022) |
Keratinocyte cancer | keratinocyte carcinoma | 78 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004592/ScoringFiles/PGS004592.txt.gz |
| PGS004903 (PRS_ALL) |
PGP000633 | Al-Janabi A et al. J Allergy Clin Immunol (2023) |
Atopic dermatitis | atopic eczema | 38 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004903/ScoringFiles/PGS004903.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM000344 | PGS000119 (BCC32) |
PSS000207| European Ancestry| 20,468 individuals |
PGP000055 | Fritsche LG et al. PLoS Genet (2019) |
Reported Trait: Skin cancer | OR: 1.32 [1.27, 1.36] | AUROC: 0.58 [0.56, 0.58] | — | age, sex, batch, PC1-4 | — |
| PPM000341 | PGS000119 (BCC32) |
PSS000209| European Ancestry| 20,468 individuals |
PGP000055 | Fritsche LG et al. PLoS Genet (2019) |
Reported Trait: Basal cell carcinoma | OR: 1.65 [1.56, 1.75] | AUROC: 0.64 [0.62, 0.66] | — | age, sex, batch, PC1-4 | — |
| PPM000347 | PGS000119 (BCC32) |
PSS000211| European Ancestry| 149,857 individuals |
PGP000055 | Fritsche LG et al. PLoS Genet (2019) |
Reported Trait: Skin cancer | OR: 1.4 [1.42, 1.48] | — | — | age, sex, genotyping array, first 4 genotype PCs | — |
| PPM000922 | PGS000339 (PRS22_CM) |
PSS000464| European Ancestry| 1,885 individuals |
PGP000106 | Law MH et al. Hum Mol Genet (2020) |
Reported Trait: Cutaneous melanoma in multiplex melanoma families | — | — | Difference of PRS (deltaPRS; unaffected melanoma family members vs. unrelated controls): 0.347 (0.104) | PCs (1-10) | *Sample overlap between the controls used in this analysis and score development |
| PPM000921 | PGS000339 (PRS22_CM) |
PSS000463| European Ancestry| 3,066 individuals |
PGP000106 | Law MH et al. Hum Mol Genet (2020) |
Reported Trait: Cutaneous melanoma in multiplex melanoma families | — | — | Difference of PRS (deltaPRS; melanoma family cases vs. unrelated controls): 0.505 (0.036) | PCs (1-10) | *Sample overlap between the controls used in this analysis and score development |
| PPM000970 | PGS000341 (GRS33_SSc) |
PSS000489| European Ancestry| 339 individuals |
PGP000110 | Bossini-Castillo L et al. Ann Rheum Dis (2020) |
Reported Trait: Systemic sclerosis | — | AUROC: 0.787 [0.73, 0.84] | — | Systemic sclerosis status, age and immune cell counts of: memory B cells, resting NK cells, M0 macrophages and activated dendritic cells | *Some overlap with score development and testing samples |
| PPM000969 | PGS000341 (GRS33_SSc) |
PSS000489| European Ancestry| 339 individuals |
PGP000110 | Bossini-Castillo L et al. Ann Rheum Dis (2020) |
Reported Trait: Systemic sclerosis | — | AUROC: 0.722 | — | Systemic sclerosis status and immune cell counts of: memory B cells, resting NK cells, M0 macrophages and activated dendritic cells | *Some overlap with score development and testing samples |
| PPM000968 | PGS000341 (GRS33_SSc) |
PSS000489| European Ancestry| 339 individuals |
PGP000110 | Bossini-Castillo L et al. Ann Rheum Dis (2020) |
Reported Trait: Systemic sclerosis | — | AUROC: 0.644 | — | — | *Some overlap with score development and testing samples |
| PPM001083 | PGS000398 (PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608) |
PSS000548| European Ancestry| 17,607 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Skin cancer | OR: 1.042 [1.003, 1.082] β: 0.0407 (0.0195) |
AUROC: 0.51 [0.499, 0.521] | Nagelkerke's Pseudo-R²: 0.00028 Brier score: 0.148 Odds Ratio (OR, top 1% vs. Rest): 1.7 [1.22, 2.38] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608 |
| PPM001084 | PGS000399 (PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608) |
PSS000548| European Ancestry| 17,607 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Skin cancer | OR: 1.158 [1.116, 1.202] β: 0.147 (0.0189) |
AUROC: 0.513 [0.503, 0.523] | Nagelkerke's Pseudo-R²: 0.00545 Brier score: 0.148 Odds Ratio (OR, top 1% vs. Rest): 1.56 [1.12, 2.16] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608 |
| PPM001085 | PGS000400 (PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608) |
PSS000548| European Ancestry| 17,607 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Skin cancer | OR: 1.342 [1.291, 1.395] β: 0.294 (0.0197) |
AUROC: 0.581 [0.57, 0.592] | Nagelkerke's Pseudo-R²: 0.0201 Brier score: 0.146 Odds Ratio (OR, top 1% vs. Rest): 2.2 [1.63, 2.98] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608 |
| PPM001086 | PGS000401 (PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608) |
PSS000548| European Ancestry| 17,607 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Skin cancer | OR: 1.342 [1.291, 1.396] β: 0.294 (0.0199) |
AUROC: 0.581 [0.57, 0.591] | Nagelkerke's Pseudo-R²: 0.0202 Brier score: 0.146 Odds Ratio (OR, top 1% vs. Rest): 2.25 [1.67, 3.03] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608 |
| PPM001087 | PGS000402 (PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608) |
PSS000548| European Ancestry| 17,607 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Skin cancer | OR: 1.366 [1.314, 1.421] β: 0.312 (0.0198) |
AUROC: 0.586 [0.576, 0.597] | Nagelkerke's Pseudo-R²: 0.0224 Brier score: 0.146 Odds Ratio (OR, top 1% vs. Rest): 2.23 [1.64, 3.03] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608 |
| PPM001088 | PGS000403 (PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608) |
PSS000548| European Ancestry| 17,607 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Skin cancer | OR: 1.359 [1.307, 1.413] β: 0.307 (0.0199) |
AUROC: 0.584 [0.573, 0.594] | Nagelkerke's Pseudo-R²: 0.0219 Brier score: 0.146 Odds Ratio (OR, top 1% vs. Rest): 1.65 [1.2, 2.27] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608 |
| PPM001089 | PGS000404 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608) |
PSS000548| European Ancestry| 17,607 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Skin cancer | OR: 1.369 [1.317, 1.422] β: 0.314 (0.0196) |
AUROC: 0.584 [0.574, 0.594] | Nagelkerke's Pseudo-R²: 0.0226 Brier score: 0.146 Odds Ratio (OR, top 1% vs. Rest): 2.3 [1.72, 3.09] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608 |
| PPM001090 | PGS000405 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608) |
PSS000548| European Ancestry| 17,607 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Skin cancer | OR: 1.338 [1.287, 1.391] β: 0.291 (0.0199) |
AUROC: 0.58 [0.57, 0.591] | Nagelkerke's Pseudo-R²: 0.0192 Brier score: 0.146 Odds Ratio (OR, top 1% vs. Rest): 2.42 [1.81, 3.24] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608 |
| PPM001091 | PGS000406 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608) |
PSS000548| European Ancestry| 17,607 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Skin cancer | OR: 1.392 [1.339, 1.447] β: 0.331 (0.0199) |
AUROC: 0.591 [0.581, 0.602] | Nagelkerke's Pseudo-R²: 0.0249 Brier score: 0.146 Odds Ratio (OR, top 1% vs. Rest): 2.51 [1.89, 3.34] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608 |
| PPM001092 | PGS000407 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608) |
PSS000548| European Ancestry| 17,607 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Skin cancer | OR: 1.38 [1.328, 1.434] β: 0.322 (0.0197) |
AUROC: 0.586 [0.575, 0.597] | Nagelkerke's Pseudo-R²: 0.0245 Brier score: 0.146 Odds Ratio (OR, top 1% vs. Rest): 2.26 [1.69, 3.03] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608 |
| PPM001118 | PGS000433 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.367 [1.31, 1.426] β: 0.312 (0.0215) |
AUROC: 0.584 [0.572, 0.598] | Nagelkerke's Pseudo-R²: 0.0215 Brier score: 0.137 Odds Ratio (OR, top 1% vs. Rest): 2.73 [2.01, 3.72] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608 |
| PPM001119 | PGS000434 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.361 [1.304, 1.42] β: 0.308 (0.0217) |
AUROC: 0.586 [0.573, 0.598] | Nagelkerke's Pseudo-R²: 0.0208 Brier score: 0.137 Odds Ratio (OR, top 1% vs. Rest): 1.99 [1.43, 2.78] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608 |
| PPM001120 | PGS000435 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.357 [1.301, 1.415] β: 0.305 (0.0215) |
AUROC: 0.584 [0.572, 0.597] | Nagelkerke's Pseudo-R²: 0.0201 Brier score: 0.137 Odds Ratio (OR, top 1% vs. Rest): 2.7 [1.99, 3.66] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608 |
| PPM001121 | PGS000436 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.361 [1.305, 1.42] β: 0.308 (0.0216) |
AUROC: 0.584 [0.571, 0.596] | Nagelkerke's Pseudo-R²: 0.021 Brier score: 0.137 Odds Ratio (OR, top 1% vs. Rest): 2.22 [1.61, 3.06] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608 |
| PPM001122 | PGS000437 (PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.352 [1.296, 1.409] β: 0.301 (0.0213) |
AUROC: 0.579 [0.566, 0.592] | Nagelkerke's Pseudo-R²: 0.0206 Brier score: 0.137 Odds Ratio (OR, top 1% vs. Rest): 2.21 [1.6, 3.06] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608 |
| PPM001123 | PGS000438 (PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.31 [1.256, 1.367] β: 0.27 (0.0216) |
AUROC: 0.575 [0.562, 0.587] | Nagelkerke's Pseudo-R²: 0.0162 Brier score: 0.137 Odds Ratio (OR, top 1% vs. Rest): 1.79 [1.28, 2.51] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608 |
| PPM001124 | PGS000439 (PRSWEB_PHECODE172.2_C44_PT_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.348 [1.293, 1.407] β: 0.299 (0.0216) |
AUROC: 0.583 [0.57, 0.595] | Nagelkerke's Pseudo-R²: 0.0197 Brier score: 0.137 Odds Ratio (OR, top 1% vs. Rest): 2.17 [1.57, 3.01] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_PT_MGI_20200608 |
| PPM001125 | PGS000440 (PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.351 [1.296, 1.409] β: 0.301 (0.0215) |
AUROC: 0.581 [0.569, 0.592] | Nagelkerke's Pseudo-R²: 0.0201 Brier score: 0.137 Odds Ratio (OR, top 1% vs. Rest): 2.55 [1.87, 3.46] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608 |
| PPM001126 | PGS000441 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.39 [1.333, 1.449] β: 0.329 (0.0214) |
AUROC: 0.586 [0.574, 0.599] | Nagelkerke's Pseudo-R²: 0.0241 Brier score: 0.136 Odds Ratio (OR, top 1% vs. Rest): 2.65 [1.94, 3.62] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608 |
| PPM001127 | PGS000442 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.357 [1.301, 1.417] β: 0.306 (0.0217) |
AUROC: 0.584 [0.572, 0.595] | Nagelkerke's Pseudo-R²: 0.0201 Brier score: 0.137 Odds Ratio (OR, top 1% vs. Rest): 2.35 [1.71, 3.22] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608 |
| PPM001128 | PGS000443 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.41 [1.352, 1.471] β: 0.344 (0.0216) |
AUROC: 0.591 [0.579, 0.603] | Nagelkerke's Pseudo-R²: 0.0259 Brier score: 0.136 Odds Ratio (OR, top 1% vs. Rest): 2.89 [2.14, 3.92] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608 |
| PPM001129 | PGS000444 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608) |
PSS000546| European Ancestry| 15,898 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Other non-epithelial cancer of skin | OR: 1.399 [1.341, 1.46] β: 0.336 (0.0216) |
AUROC: 0.59 [0.578, 0.601] | Nagelkerke's Pseudo-R²: 0.025 Brier score: 0.136 Odds Ratio (OR, top 1% vs. Rest): 3.5 [2.63, 4.65] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608 |
| PPM001130 | PGS000445 (PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.334 [1.264, 1.409] β: 0.289 (0.0278) |
AUROC: 0.571 [0.555, 0.587] | Nagelkerke's Pseudo-R²: 0.0184 Brier score: 0.108 Odds Ratio (OR, top 1% vs. Rest): 2.54 [1.72, 3.74] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608 |
| PPM001131 | PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.291 [1.221, 1.366] β: 0.256 (0.0286) |
AUROC: 0.575 [0.559, 0.591] | Nagelkerke's Pseudo-R²: 0.0139 Brier score: 0.109 Odds Ratio (OR, top 1% vs. Rest): 1.42 [0.871, 2.33] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608 |
| PPM018452 | PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Skin colour | β: -0.02375 | — | R²: 0.01374 | — | — |
| PPM018453 | PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Freckles | β: 0.04205 | — | R²: 0.02091 | — | — |
| PPM018454 | PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Ease suntan | β: -0.0266 | — | R²: 0.01362 | — | — |
| PPM018455 | PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Ease sunburn | β: 0.04289 | — | R²: 0.01118 | — | — |
| PPM018456 | PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Phototype score | β: -0.62656 | — | R²: 0.03377 | — | — |
| PPM018457 | PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Fitzpatrick scale | β: -0.02673 | — | R²: 0.0294 | — | — |
| PPM018458 | PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Red hair | β: 1.77173 | — | R²: 0.05421 pseudo R²: 0.05421 |
— | — |
| PPM001132 | PGS000447 (PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.398 [1.322, 1.477] β: 0.335 (0.0282) |
AUROC: 0.591 [0.575, 0.607] | Nagelkerke's Pseudo-R²: 0.0237 Brier score: 0.108 Odds Ratio (OR, top 1% vs. Rest): 2.5 [1.68, 3.71] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608 |
| PPM001133 | PGS000448 (PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.411 [1.335, 1.491] β: 0.344 (0.0282) |
AUROC: 0.587 [0.57, 0.604] | Nagelkerke's Pseudo-R²: 0.0254 Brier score: 0.108 Odds Ratio (OR, top 1% vs. Rest): 2.93 [2.03, 4.25] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608 |
| PPM001134 | PGS000449 (PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.093 [1.034, 1.155] β: 0.0888 (0.0282) |
AUROC: 0.525 [0.509, 0.54] | Nagelkerke's Pseudo-R²: 0.00141 Brier score: 0.109 Odds Ratio (OR, top 1% vs. Rest): 1.65 [1.04, 2.61] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608 |
| PPM001135 | PGS000450 (PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.079 [1.022, 1.139] β: 0.0759 (0.0278) |
AUROC: 0.504 [0.489, 0.52] | Nagelkerke's Pseudo-R²: 0.00145 Brier score: 0.109 Odds Ratio (OR, top 1% vs. Rest): 1.42 [0.882, 2.3] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608 |
| PPM001136 | PGS000451 (PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.144 [1.084, 1.208] β: 0.135 (0.0278) |
AUROC: 0.521 [0.506, 0.536] | Nagelkerke's Pseudo-R²: 0.00396 Brier score: 0.109 Odds Ratio (OR, top 1% vs. Rest): 2.44 [1.65, 3.62] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608 |
| PPM001137 | PGS000452 (PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.663 [1.57, 1.761] β: 0.508 (0.0293) |
AUROC: 0.632 [0.616, 0.647] | Nagelkerke's Pseudo-R²: 0.0487 Brier score: 0.106 Odds Ratio (OR, top 1% vs. Rest): 3.61 [2.53, 5.15] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608 |
| PPM001138 | PGS000453 (PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608) |
PSS000568| European Ancestry| 60,018 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.511 [1.47, 1.554] β: 0.413 (0.0142) |
AUROC: 0.611 [0.604, 0.619] | Nagelkerke's Pseudo-R²: 0.0301 Brier score: 0.0813 Odds Ratio (OR, top 1% vs. Rest): 2.8 [2.33, 3.36] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608 |
| PPM001139 | PGS000454 (PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.661 [1.568, 1.759] β: 0.507 (0.0293) |
AUROC: 0.632 [0.616, 0.647] | Nagelkerke's Pseudo-R²: 0.0489 Brier score: 0.106 Odds Ratio (OR, top 1% vs. Rest): 3.79 [2.68, 5.35] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608 |
| PPM001140 | PGS000455 (PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608) |
PSS000568| European Ancestry| 60,018 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.511 [1.47, 1.554] β: 0.413 (0.0142) |
AUROC: 0.611 [0.604, 0.619] | Nagelkerke's Pseudo-R²: 0.0301 Brier score: 0.0813 Odds Ratio (OR, top 1% vs. Rest): 2.8 [2.33, 3.36] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608 |
| PPM001141 | PGS000456 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.633 [1.541, 1.729] β: 0.49 (0.0293) |
AUROC: 0.63 [0.615, 0.646] | Nagelkerke's Pseudo-R²: 0.0456 Brier score: 0.106 Odds Ratio (OR, top 1% vs. Rest): 3.95 [2.79, 5.58] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608 |
| PPM001142 | PGS000457 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608) |
PSS000568| European Ancestry| 60,018 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.535 [1.493, 1.579] β: 0.429 (0.0144) |
AUROC: 0.617 [0.609, 0.625] | Nagelkerke's Pseudo-R²: 0.0322 Brier score: 0.0813 Odds Ratio (OR, top 1% vs. Rest): 3.11 [2.6, 3.71] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608 |
| PPM001143 | PGS000458 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608) |
PSS000544| European Ancestry| 11,322 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.634 [1.542, 1.732] β: 0.491 (0.0296) |
AUROC: 0.628 [0.612, 0.644] | Nagelkerke's Pseudo-R²: 0.0457 Brier score: 0.106 Odds Ratio (OR, top 1% vs. Rest): 4.03 [2.86, 5.69] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608 |
| PPM001144 | PGS000459 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608) |
PSS000568| European Ancestry| 60,018 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Basal cell carcinoma | OR: 1.528 [1.485, 1.572] β: 0.424 (0.0144) |
AUROC: 0.615 [0.608, 0.623] | Nagelkerke's Pseudo-R²: 0.0314 Brier score: 0.0813 Odds Ratio (OR, top 1% vs. Rest): 3.05 [2.55, 3.64] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608 |
| PPM001154 | PGS000469 (PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608) |
PSS000547| European Ancestry| 5,500 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Carcinoma in situ of skin | OR: 1.09 [1.001, 1.188] β: 0.0865 (0.0437) |
AUROC: 0.524 [0.499, 0.549] | Nagelkerke's Pseudo-R²: 0.00141 Brier score: 0.0939 Odds Ratio (OR, top 1% vs. Rest): 1.48 [0.703, 3.1] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608 |
| PPM001155 | PGS000470 (PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608) |
PSS000547| European Ancestry| 5,500 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Carcinoma in situ of skin | OR: 1.308 [1.208, 1.417] β: 0.269 (0.0407) |
AUROC: 0.557 [0.531, 0.582] | Nagelkerke's Pseudo-R²: 0.0154 Brier score: 0.093 Odds Ratio (OR, top 1% vs. Rest): 2.45 [1.34, 4.45] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608 |
| PPM001156 | PGS000471 (PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608) |
PSS000547| European Ancestry| 5,500 individuals |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Reported Trait: Carcinoma in situ of skin | OR: 1.401 [1.297, 1.513] β: 0.337 (0.0393) |
AUROC: 0.569 [0.541, 0.595] | Nagelkerke's Pseudo-R²: 0.0255 Brier score: 0.0923 Odds Ratio (OR, top 1% vs. Rest): 3.77 [2.24, 6.34] |
age, sex, batch PCs 1-4 | Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608 |
| PPM001670 | PGS000730 (PRS_BCC) |
PSS000871| European Ancestry| 88,924 individuals |
PGP000138 | Fontanillas P et al. Nat Commun (2021) |
Reported Trait: Basal cell carcinoma | OR: 1.57 [1.55, 1.6] | AUROC: 0.624 | — | — | — |
| PPM001761 | PGS000738 (CONFIRMED_PGS) |
PSS000907| European Ancestry| 4,008 individuals |
PGP000145 | Roberts GHL et al. Am J Hum Genet (2019) |
Reported Trait: Vitiligo | — | — | Odds Ratio (OR, top 20% vs remaining 80% of score distribution): 4.87 [4.21, 5.64] | — | — |
| PPM001762 | PGS000738 (CONFIRMED_PGS) |
PSS000907| European Ancestry| 4,008 individuals |
PGP000145 | Roberts GHL et al. Am J Hum Genet (2019) |
Reported Trait: Vitiligo | — | — | Odds Ratio (OR, top 10% vs remaining 90% of score distribution): 5.26 [4.42, 6.29] | — | — |
| PPM001763 | PGS000738 (CONFIRMED_PGS) |
PSS000907| European Ancestry| 4,008 individuals |
PGP000145 | Roberts GHL et al. Am J Hum Genet (2019) |
Reported Trait: Vitiligo | — | — | Odds Ratio (OR, top 10% vs remaining 95% of score distribution): 6.2 [4.96, 7.79] | — | — |
| PPM001764 | PGS000738 (CONFIRMED_PGS) |
PSS000907| European Ancestry| 4,008 individuals |
PGP000145 | Roberts GHL et al. Am J Hum Genet (2019) |
Reported Trait: Vitiligo | — | — | Odds Ratio (OR, top 1% vs remaining 99% of score distribution): 8.79 [5.85, 13.78] | — | — |
| PPM018437 | PGS000738 (CONFIRMED_PGS) |
PSS010969| European Ancestry| 4,945 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Fitzpatrick scale | β: 0.02234 | — | R²: 0.02897 | — | — |
| PPM018438 | PGS000738 (CONFIRMED_PGS) |
PSS010968| European Ancestry| 4,702 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Red hair | β: 0.69478 | — | pseudo R²: 0.03857 | — | — |
| PPM018435 | PGS000738 (CONFIRMED_PGS) |
PSS010977| European Ancestry| 4,987 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Freckles | β: -0.04382 | — | R²: 0.02103 | — | — |
| PPM018436 | PGS000738 (CONFIRMED_PGS) |
PSS010974| European Ancestry| 4,979 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Phototype score | β: 0.4039 | — | R²: 0.03252 | — | — |
| PPM001935 | PGS000760 (VIT) |
PSS000970| European Ancestry| 1,584 individuals |
PGP000164 | Khan Z et al. Nat Commun (2021) |
Reported Trait: anti-PD-L1 induced hypothyroidism in cancer patients | HR: 1.41 [1.22, 1.61] | — | meta-analysis p-value: 1.10e-06 | 5 genotype PCs | — |
| PPM001963 | PGS000766 (PRS56_CM) |
PSS000982| European Ancestry| 12,712 individuals |
PGP000172 | Bakshi A et al. J Natl Cancer Inst (2021) |
Reported Trait: Incident cutaneous melanoma | — | — | Hazard Ratio (HR, top 20% vs bottom 20%): 2.51 [1.28, 4.92] | — | Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control. |
| PPM001964 | PGS000766 (PRS56_CM) |
PSS000982| European Ancestry| 12,712 individuals |
PGP000172 | Bakshi A et al. J Natl Cancer Inst (2021) |
Reported Trait: Incident cutaneous melanoma (males) | — | — | Hazard Ratio (HR, top 20% vs bottom 20%): 3.7 [1.37, 9.98] | — | Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control. |
| PPM001965 | PGS000766 (PRS56_CM) |
PSS000982| European Ancestry| 12,712 individuals |
PGP000172 | Bakshi A et al. J Natl Cancer Inst (2021) |
Reported Trait: Incident cutaneous melanoma (males) | — | — | Hazard Ratio (HR, middle 60% vs bottom 20%): 2.61 [1.03, 6.63] | — | Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control. |
| PPM001966 | PGS000766 (PRS56_CM) |
PSS000982| European Ancestry| 12,712 individuals |
PGP000172 | Bakshi A et al. J Natl Cancer Inst (2021) |
Reported Trait: Prevalent cutaneous melanoma | OR: 1.55 [1.42, 1.69] | AUROC: 0.64 [0.62, 0.66] | Odds Ratio (OR, top 20% vs bottom 20%): 3.66 [2.69, 5.05] | Sex, family history | Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control. |
| PPM001967 | PGS000766 (PRS56_CM) |
PSS000982| European Ancestry| 12,712 individuals |
PGP000172 | Bakshi A et al. J Natl Cancer Inst (2021) |
Reported Trait: Prevalent cutaneous melanoma (males) | OR: 1.39 [1.23, 1.57] | — | — | Family history | Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control. |
| PPM001968 | PGS000766 (PRS56_CM) |
PSS000982| European Ancestry| 12,712 individuals |
PGP000172 | Bakshi A et al. J Natl Cancer Inst (2021) |
Reported Trait: Prevalent cutaneous melanoma (females) | OR: 1.72 [1.53, 1.94] | — | — | Family history | Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control. |
| PPM001962 | PGS000766 (PRS56_CM) |
PSS000982| European Ancestry| 12,712 individuals |
PGP000172 | Bakshi A et al. J Natl Cancer Inst (2021) |
Reported Trait: Incident cutaneous melanoma | HR: 1.46 [1.2, 1.77] | C-index: 0.643 [0.584, 0.702] | — | Sex, melanoma family history, treatment (aspirin/placebo), age at enrolment, PRS*treatment | Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control. |
| PPM007462 | PGS000927 (GBE_HC1158) |
PSS004153| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other dermatitis | — | AUROC: 0.61027 [0.57953, 0.64101] | R²: 0.02035 Incremental AUROC (full-covars): 0.00207 PGS R2 (no covariates): 0.00268 PGS AUROC (no covariates): 0.5378 [0.50673, 0.56886] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007463 | PGS000927 (GBE_HC1158) |
PSS004154| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other dermatitis | — | AUROC: 0.57706 [0.52927, 0.62486] | R²: 0.02951 Incremental AUROC (full-covars): 0.01147 PGS R2 (no covariates): 0.00458 PGS AUROC (no covariates): 0.5429 [0.49389, 0.59191] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007464 | PGS000927 (GBE_HC1158) |
PSS004155| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other dermatitis | — | AUROC: 0.54587 [0.53304, 0.5587] | R²: 0.00506 Incremental AUROC (full-covars): 0.01785 PGS R2 (no covariates): 0.00339 PGS AUROC (no covariates): 0.53939 [0.52639, 0.55239] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007465 | PGS000927 (GBE_HC1158) |
PSS004156| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other dermatitis | — | AUROC: 0.58261 [0.56273, 0.60248] | R²: 0.01573 Incremental AUROC (full-covars): 0.00482 PGS R2 (no covariates): 0.00187 PGS AUROC (no covariates): 0.52627 [0.50591, 0.54663] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007466 | PGS000927 (GBE_HC1158) |
PSS004157| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other dermatitis | — | AUROC: 0.56752 [0.56014, 0.57491] | R²: 0.01047 Incremental AUROC (full-covars): 0.01697 PGS R2 (no covariates): 0.00542 PGS AUROC (no covariates): 0.54889 [0.54154, 0.55624] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007546 | PGS000944 (GBE_HC261) |
PSS004384| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Eczema/dermatitis | — | AUROC: 0.62856 [0.58377, 0.67334] | R²: 0.02337 Incremental AUROC (full-covars): 0.00187 PGS R2 (no covariates): 0.00173 PGS AUROC (no covariates): 0.52778 [0.48039, 0.57516] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007547 | PGS000944 (GBE_HC261) |
PSS004385| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Eczema/dermatitis | — | AUROC: 0.59588 [0.52553, 0.66622] | R²: 0.02855 Incremental AUROC (full-covars): 0.02432 PGS R2 (no covariates): 0.0116 PGS AUROC (no covariates): 0.58664 [0.52213, 0.65115] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007548 | PGS000944 (GBE_HC261) |
PSS004386| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Eczema/dermatitis | — | AUROC: 0.56459 [0.54541, 0.58377] | R²: 0.00802 Incremental AUROC (full-covars): 0.01208 PGS R2 (no covariates): 0.00353 PGS AUROC (no covariates): 0.54597 [0.52632, 0.56561] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007549 | PGS000944 (GBE_HC261) |
PSS004387| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Eczema/dermatitis | — | AUROC: 0.56106 [0.52439, 0.59773] | R²: 0.00683 Incremental AUROC (full-covars): -0.0012 PGS R2 (no covariates): 0.00011 PGS AUROC (no covariates): 0.51686 [0.48122, 0.5525] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007550 | PGS000944 (GBE_HC261) |
PSS004388| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Eczema/dermatitis | — | AUROC: 0.57099 [0.55943, 0.58256] | R²: 0.00884 Incremental AUROC (full-covars): 0.02521 PGS R2 (no covariates): 0.00527 PGS AUROC (no covariates): 0.5556 [0.54396, 0.56724] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007639 | PGS000963 (GBE_HC1184) |
PSS004168| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE follicular cysts of skin and subcutaneous tissue | — | AUROC: 0.56399 [0.51489, 0.61308] | R²: 0.01027 Incremental AUROC (full-covars): -0.00108 PGS R2 (no covariates): 0.00011 PGS AUROC (no covariates): 0.51899 [0.4747, 0.56328] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007640 | PGS000963 (GBE_HC1184) |
PSS004169| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE follicular cysts of skin and subcutaneous tissue | — | AUROC: 0.64299 [0.54406, 0.74191] | R²: 0.02377 Incremental AUROC (full-covars): 0.01591 PGS R2 (no covariates): 0.00898 PGS AUROC (no covariates): 0.60189 [0.51478, 0.689] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007641 | PGS000963 (GBE_HC1184) |
PSS004170| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE follicular cysts of skin and subcutaneous tissue | — | AUROC: 0.61353 [0.59056, 0.63651] | R²: 0.02635 Incremental AUROC (full-covars): 0.0691 PGS R2 (no covariates): 0.02281 PGS AUROC (no covariates): 0.59346 [0.56998, 0.61695] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007642 | PGS000963 (GBE_HC1184) |
PSS004171| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE follicular cysts of skin and subcutaneous tissue | — | AUROC: 0.64204 [0.6008, 0.68328] | R²: 0.03504 Incremental AUROC (full-covars): 0.04562 PGS R2 (no covariates): 0.02125 PGS AUROC (no covariates): 0.56287 [0.51348, 0.61226] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007643 | PGS000963 (GBE_HC1184) |
PSS004172| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE follicular cysts of skin and subcutaneous tissue | — | AUROC: 0.6146 [0.60131, 0.6279] | R²: 0.02902 Incremental AUROC (full-covars): 0.06632 PGS R2 (no covariates): 0.02439 PGS AUROC (no covariates): 0.58761 [0.57398, 0.60124] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007818 | PGS001011 (GBE_HC534) |
PSS004521| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE viral warts | — | AUROC: 0.62763 [0.56904, 0.68622] | R²: 0.01913 Incremental AUROC (full-covars): -0.00455 PGS R2 (no covariates): 0.00116 PGS AUROC (no covariates): 0.48242 [0.41987, 0.54497] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007819 | PGS001011 (GBE_HC534) |
PSS004522| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE viral warts | — | AUROC: 0.65545 [0.57671, 0.73418] | R²: 0.03677 Incremental AUROC (full-covars): -0.00026 PGS R2 (no covariates): 1e-05 PGS AUROC (no covariates): 0.50846 [0.40705, 0.60986] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007820 | PGS001011 (GBE_HC534) |
PSS004523| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE viral warts | — | AUROC: 0.56023 [0.54032, 0.58015] | R²: 0.0051 Incremental AUROC (full-covars): 0.01103 PGS R2 (no covariates): 0.00154 PGS AUROC (no covariates): 0.53437 [0.51402, 0.55472] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007821 | PGS001011 (GBE_HC534) |
PSS004524| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE viral warts | — | AUROC: 0.5793 [0.54592, 0.61268] | R²: 0.01114 Incremental AUROC (full-covars): 0.00245 PGS R2 (no covariates): 0.00048 PGS AUROC (no covariates): 0.51036 [0.47743, 0.54328] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007822 | PGS001011 (GBE_HC534) |
PSS004525| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE viral warts | — | AUROC: 0.56004 [0.54811, 0.57198] | R²: 0.00576 Incremental AUROC (full-covars): 0.00636 PGS R2 (no covariates): 0.00167 PGS AUROC (no covariates): 0.53057 [0.51862, 0.54252] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007958 | PGS001040 (GBE_cancer1060) |
PSS007651| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Non-melanoma skin cancer | — | AUROC: 0.80478 [0.72556, 0.884] | R²: 0.07029 Incremental AUROC (full-covars): -0.00066 PGS R2 (no covariates): 0.00133 PGS AUROC (no covariates): 0.54127 [0.39017, 0.69237] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007959 | PGS001040 (GBE_cancer1060) |
PSS007652| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Non-melanoma skin cancer | — | AUROC: 0.86455 [0.80574, 0.92335] | R²: 0.12918 Incremental AUROC (full-covars): -0.00442 PGS R2 (no covariates): 0.00152 PGS AUROC (no covariates): 0.4523 [0.1694, 0.73519] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007960 | PGS001040 (GBE_cancer1060) |
PSS007653| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Non-melanoma skin cancer | — | AUROC: 0.73342 [0.72065, 0.74619] | R²: 0.10751 Incremental AUROC (full-covars): 0.0378 PGS R2 (no covariates): 0.05185 PGS AUROC (no covariates): 0.66327 [0.64889, 0.67765] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007961 | PGS001040 (GBE_cancer1060) |
PSS007654| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Non-melanoma skin cancer | — | AUROC: 0.76366 [0.66832, 0.85901] | R²: 0.06447 Incremental AUROC (full-covars): -0.00934 PGS R2 (no covariates): 0.00078 PGS AUROC (no covariates): 0.47181 [0.35611, 0.58752] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007962 | PGS001040 (GBE_cancer1060) |
PSS007655| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Non-melanoma skin cancer | — | AUROC: 0.70656 [0.69863, 0.7145] | R²: 0.08615 Incremental AUROC (full-covars): 0.04717 PGS R2 (no covariates): 0.03949 PGS AUROC (no covariates): 0.64209 [0.6334, 0.65078] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM018463 | PGS001040 (GBE_cancer1060) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Ease sunburn | β: 0.08836 | — | R²: 0.01475 | — | — |
| PPM018465 | PGS001040 (GBE_cancer1060) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Fitzpatrick scale | β: -0.0689 | — | R²: 0.03786 | — | — |
| PPM018459 | PGS001040 (GBE_cancer1060) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Eye colour | β: -0.11302 | — | R²: 0.0106 | — | — |
| PPM018460 | PGS001040 (GBE_cancer1060) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Skin colour | β: -0.05462 | — | R²: 0.01757 | — | — |
| PPM018461 | PGS001040 (GBE_cancer1060) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Freckles | β: 0.09955 | — | R²: 0.02643 | — | — |
| PPM018462 | PGS001040 (GBE_cancer1060) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Ease suntan | β: -0.06804 | — | R²: 0.01892 | — | — |
| PPM018464 | PGS001040 (GBE_cancer1060) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Phototype score | β: -1.51455 | — | R²: 0.04441 | — | — |
| PPM018466 | PGS001040 (GBE_cancer1060) |
PSS010980| European Ancestry| 4,797 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Blond hair | β: 1.14835 | — | pseudo R²: 0.01006 | — | — |
| PPM007963 | PGS001041 (GBE_cancer1003) |
PSS007621| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Skin cancer | — | AUROC: 0.78777 [0.7126, 0.86293] | R²: 0.06151 Incremental AUROC (full-covars): 0.00386 PGS R2 (no covariates): 0.00103 PGS AUROC (no covariates): 0.5229 [0.37426, 0.67153] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007964 | PGS001041 (GBE_cancer1003) |
PSS007622| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Skin cancer | — | AUROC: 0.83061 [0.75233, 0.9089] | R²: 0.10839 Incremental AUROC (full-covars): 0.0017 PGS R2 (no covariates): 0.00376 PGS AUROC (no covariates): 0.56985 [0.36492, 0.77477] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007965 | PGS001041 (GBE_cancer1003) |
PSS007623| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Skin cancer | — | AUROC: 0.71667 [0.70431, 0.72902] | R²: 0.09613 Incremental AUROC (full-covars): 0.03439 PGS R2 (no covariates): 0.04566 PGS AUROC (no covariates): 0.65086 [0.63722, 0.6645] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007966 | PGS001041 (GBE_cancer1003) |
PSS007624| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Skin cancer | — | AUROC: 0.76232 [0.67332, 0.85131] | R²: 0.07091 Incremental AUROC (full-covars): -0.01012 PGS R2 (no covariates): 6e-05 PGS AUROC (no covariates): 0.49291 [0.37897, 0.60686] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007967 | PGS001041 (GBE_cancer1003) |
PSS007625| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Skin cancer | — | AUROC: 0.6935 [0.68584, 0.70116] | R²: 0.07834 Incremental AUROC (full-covars): 0.04393 PGS R2 (no covariates): 0.03573 PGS AUROC (no covariates): 0.63289 [0.62459, 0.64118] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008383 | PGS001131 (GBE_HC530) |
PSS004516| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE zoster [herpes zoster] | — | AUROC: 0.66564 [0.59848, 0.7328] | R²: 0.02855 Incremental AUROC (full-covars): 0.00653 PGS R2 (no covariates): 0.00463 PGS AUROC (no covariates): 0.5717 [0.50786, 0.63553] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008384 | PGS001131 (GBE_HC530) |
PSS004517| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE zoster [herpes zoster] | — | AUROC: 0.6496 [0.5711, 0.7281] | R²: 0.02884 Incremental AUROC (full-covars): 0.00319 PGS R2 (no covariates): 1e-05 PGS AUROC (no covariates): 0.49296 [0.39896, 0.58695] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008385 | PGS001131 (GBE_HC530) |
PSS004518| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE zoster [herpes zoster] | — | AUROC: 0.61339 [0.59385, 0.63293] | R²: 0.01934 Incremental AUROC (full-covars): 0.00397 PGS R2 (no covariates): 0.00108 PGS AUROC (no covariates): 0.52734 [0.50543, 0.54926] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008386 | PGS001131 (GBE_HC530) |
PSS004519| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE zoster [herpes zoster] | — | AUROC: 0.64482 [0.60407, 0.68558] | R²: 0.02792 Incremental AUROC (full-covars): -0.00388 PGS R2 (no covariates): 0.00012 PGS AUROC (no covariates): 0.49268 [0.44738, 0.53799] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008387 | PGS001131 (GBE_HC530) |
PSS004520| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE zoster [herpes zoster] | — | AUROC: 0.60947 [0.59775, 0.62119] | R²: 0.0198 Incremental AUROC (full-covars): 0.00787 PGS R2 (no covariates): 0.00329 PGS AUROC (no covariates): 0.54558 [0.53361, 0.55755] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008427 | PGS001140 (GBE_HC1190) |
PSS004178| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seborrhoeic keratosis | — | AUROC: 0.69791 [0.62772, 0.7681] | R²: 0.0531 Incremental AUROC (full-covars): 0.01676 PGS R2 (no covariates): 0.01004 PGS AUROC (no covariates): 0.5859 [0.50622, 0.66558] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008428 | PGS001140 (GBE_HC1190) |
PSS004179| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seborrhoeic keratosis | — | AUROC: 0.74674 [0.66312, 0.83035] | R²: 0.10541 Incremental AUROC (full-covars): -0.00457 PGS R2 (no covariates): 0.01744 PGS AUROC (no covariates): 0.62007 [0.51848, 0.72165] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008429 | PGS001140 (GBE_HC1190) |
PSS004180| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seborrhoeic keratosis | — | AUROC: 0.63238 [0.61781, 0.64695] | R²: 0.03162 Incremental AUROC (full-covars): 0.01328 PGS R2 (no covariates): 0.00595 PGS AUROC (no covariates): 0.55636 [0.54088, 0.57185] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008430 | PGS001140 (GBE_HC1190) |
PSS004181| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seborrhoeic keratosis | — | AUROC: 0.65125 [0.6056, 0.6969] | Incremental AUROC (full-covars): 0.00972 R²: 0.03155 PGS R2 (no covariates): 0.00354 PGS AUROC (no covariates): 0.54802 [0.49607, 0.59996] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008431 | PGS001140 (GBE_HC1190) |
PSS004182| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seborrhoeic keratosis | — | AUROC: 0.62735 [0.61905, 0.63565] | R²: 0.03214 Incremental AUROC (full-covars): 0.01502 PGS R2 (no covariates): 0.00744 PGS AUROC (no covariates): 0.56248 [0.55356, 0.57141] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008790 | PGS001257 (GBE_INI1737) |
PSS004876| African Ancestry| 5,650 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Childhood sunburn | — | — | R²: 9e-05 [-0.00037, 0.00054] Incremental R2 (full-covars): -0.00203 PGS R2 (no covariates): 0.0 [-0.00007, 0.00008] |
age, sex, UKB array type, Genotype PCs | — |
| PPM008791 | PGS001257 (GBE_INI1737) |
PSS004877| East Asian Ancestry| 1,297 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Childhood sunburn | — | — | R²: 0.01343 [0.0026, 0.02427] Incremental R2 (full-covars): 0.00126 PGS R2 (no covariates): 0.00125 [-0.0021, 0.0046] |
age, sex, UKB array type, Genotype PCs | — |
| PPM008792 | PGS001257 (GBE_INI1737) |
PSS004878| European Ancestry| 19,358 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Childhood sunburn | — | — | R²: 0.03588 [0.03135, 0.04042] Incremental R2 (full-covars): 0.01262 PGS R2 (no covariates): 0.01397 [0.01107, 0.01686] |
age, sex, UKB array type, Genotype PCs | — |
| PPM008793 | PGS001257 (GBE_INI1737) |
PSS004879| South Asian Ancestry| 6,219 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Childhood sunburn | — | — | R²: 0.00339 [0.00082, 0.00595] Incremental R2 (full-covars): -0.00105 PGS R2 (no covariates): 0.00105 [-0.00038, 0.00249] |
age, sex, UKB array type, Genotype PCs | — |
| PPM008794 | PGS001257 (GBE_INI1737) |
PSS004880| European Ancestry| 50,754 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Childhood sunburn | — | — | R²: 0.00954 [0.00808, 0.011] Incremental R2 (full-covars): 0.00533 PGS R2 (no covariates): 0.00558 [0.00446, 0.0067] |
age, sex, UKB array type, Genotype PCs | — |
| PPM009053 | PGS001312 (GBE_HC38) |
PSS004471| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriasis | — | AUROC: 0.73107 [0.60624, 0.85591] | R²: 0.06593 Incremental AUROC (full-covars): 0.0282 PGS R2 (no covariates): 0.01927 PGS AUROC (no covariates): 0.62557 [0.48848, 0.76266] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009054 | PGS001312 (GBE_HC38) |
PSS004472| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriasis | — | AUROC: 0.88867 [0.80531, 0.97202] | R²: 0.24575 Incremental AUROC (full-covars): 0.01187 PGS R2 (no covariates): 0.00399 PGS AUROC (no covariates): 0.57774 [0.40533, 0.75016] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009055 | PGS001312 (GBE_HC38) |
PSS004473| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriasis | — | AUROC: 0.68424 [0.65757, 0.71091] | R²: 0.05057 Incremental AUROC (full-covars): 0.0981 PGS R2 (no covariates): 0.04137 PGS AUROC (no covariates): 0.66409 [0.63596, 0.69222] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009056 | PGS001312 (GBE_HC38) |
PSS004474| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriasis | — | AUROC: 0.6849 [0.63397, 0.73584] | R²: 0.0448 Incremental AUROC (full-covars): 0.052 PGS R2 (no covariates): 0.02087 PGS AUROC (no covariates): 0.64825 [0.59861, 0.6979] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009057 | PGS001312 (GBE_HC38) |
PSS004475| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriasis | — | AUROC: 0.69754 [0.68165, 0.71343] | R²: 0.05574 Incremental AUROC (full-covars): 0.14505 PGS R2 (no covariates): 0.05226 PGS AUROC (no covariates): 0.69158 [0.6754, 0.70775] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009058 | PGS001313 (GBE_HC1159) |
PSS004158| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE psoriasis | — | AUROC: 0.69906 [0.60273, 0.7954] | R²: 0.04185 Incremental AUROC (full-covars): 0.01899 PGS R2 (no covariates): 0.00732 PGS AUROC (no covariates): 0.62223 [0.54291, 0.70154] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009059 | PGS001313 (GBE_HC1159) |
PSS004159| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE psoriasis | — | AUROC: 0.72306 [0.61623, 0.82989] | R²: 0.09162 Incremental AUROC (full-covars): 0.00222 PGS R2 (no covariates): 0.00378 PGS AUROC (no covariates): 0.48492 [0.37014, 0.5997] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009060 | PGS001313 (GBE_HC1159) |
PSS004160| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE psoriasis | — | AUROC: 0.66545 [0.64532, 0.68558] | R²: 0.04468 Incremental AUROC (full-covars): 0.07449 PGS R2 (no covariates): 0.0337 PGS AUROC (no covariates): 0.64565 [0.62471, 0.66658] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009061 | PGS001313 (GBE_HC1159) |
PSS004161| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE psoriasis | — | AUROC: 0.63418 [0.59417, 0.67419] | R²: 0.0236 Incremental AUROC (full-covars): 0.05154 PGS R2 (no covariates): 0.0123 PGS AUROC (no covariates): 0.60455 [0.56482, 0.64428] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009062 | PGS001313 (GBE_HC1159) |
PSS004162| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE psoriasis | — | AUROC: 0.67543 [0.66285, 0.68801] | R²: 0.05117 Incremental AUROC (full-covars): 0.13853 PGS R2 (no covariates): 0.04966 PGS AUROC (no covariates): 0.6729 [0.66027, 0.68553] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005215 | PGS001536 (GBE_HC1188) |
PSS004173| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE vitiligo | — | AUROC: 0.63509 [0.52563, 0.74454] | R²: 0.01654 Incremental AUROC (full-covars): -0.00281 PGS R2 (no covariates): 0.0 PGS AUROC (no covariates): 0.51169 [0.39527, 0.62811] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005216 | PGS001536 (GBE_HC1188) |
PSS004174| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE vitiligo | — | AUROC: 0.82774 [0.75298, 0.90249] | R²: 0.08055 Incremental AUROC (full-covars): 0.01924 PGS R2 (no covariates): 0.00431 PGS AUROC (no covariates): 0.57823 [0.37976, 0.7767] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005217 | PGS001536 (GBE_HC1188) |
PSS004175| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE vitiligo | — | AUROC: 0.6991 [0.61917, 0.77902] | R²: 0.03993 Incremental AUROC (full-covars): 0.01341 PGS R2 (no covariates): 0.00254 PGS AUROC (no covariates): 0.55625 [0.47549, 0.63701] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005218 | PGS001536 (GBE_HC1188) |
PSS004176| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE vitiligo | — | AUROC: 0.64566 [0.58746, 0.70386] | R²: 0.02575 Incremental AUROC (full-covars): 0.0309 PGS R2 (no covariates): 0.01048 PGS AUROC (no covariates): 0.60302 [0.5391, 0.66694] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005219 | PGS001536 (GBE_HC1188) |
PSS004177| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE vitiligo | — | AUROC: 0.63449 [0.58754, 0.68144] | R²: 0.01686 Incremental AUROC (full-covars): 0.08163 PGS R2 (no covariates): 0.01621 PGS AUROC (no covariates): 0.64193 [0.59907, 0.68478] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009229 | PGS001773 (PRS_atopicDermatitis) |
PSS007661| Multi-ancestry (including European)| 676 individuals |
PGP000253 | Simard M et al. J Allergy Clin Immunol (2020) |
Reported Trait: Moderate-to-severe aotpic dermatitis | — | AUROC: 0.93 | R²: 0.49 | Age, sex, father's ethnicity, mother ethnicity | Nagelkerke's R^2, only unrelated individuals were considered in the analyses |
| PPM009230 | PGS001773 (PRS_atopicDermatitis) |
PSS007661| Multi-ancestry (including European)| 676 individuals |
PGP000253 | Simard M et al. J Allergy Clin Immunol (2020) |
Reported Trait: Food allergy | — | AUROC: 0.75 | — | Age, sex, father's ethnicity, mother ethnicity | Only unrelated individuals were considered in the analyses |
| PPM009231 | PGS001773 (PRS_atopicDermatitis) |
PSS007661| Multi-ancestry (including European)| 676 individuals |
PGP000253 | Simard M et al. J Allergy Clin Immunol (2020) |
Reported Trait: Allergic asthma | — | AUROC: 0.75 | — | Age, sex, father's ethnicity, mother ethnicity | Only unrelated individuals were considered in the analyses |
| PPM009232 | PGS001773 (PRS_atopicDermatitis) |
PSS007661| Multi-ancestry (including European)| 676 individuals |
PGP000253 | Simard M et al. J Allergy Clin Immunol (2020) |
Reported Trait: Allergic rhinitis | — | AUROC: 0.77 | — | Age, sex, father's ethnicity, mother ethnicity | Only unrelated individuals were considered in the analyses |
| PPM009332 | PGS001803 (portability-PLR_172) |
PSS008601| European Ancestry| 6,656 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.0762 [0.0522, 0.1001] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009333 | PGS001803 (portability-PLR_172) |
PSS008379| Greater Middle Eastern Ancestry| 1,200 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.0694 [0.0123, 0.1259] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009334 | PGS001803 (portability-PLR_172) |
PSS008155| South Asian Ancestry| 6,328 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): -0.0135 [-0.0382, 0.0112] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009330 | PGS001803 (portability-PLR_172) |
PSS009273| European Ancestry| 19,990 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.1136 [0.0999, 0.1272] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009331 | PGS001803 (portability-PLR_172) |
PSS009047| European Ancestry| 4,134 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.0962 [0.0659, 0.1264] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009335 | PGS001803 (portability-PLR_172) |
PSS007943| East Asian Ancestry| 1,810 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.0054 [-0.041, 0.0517] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009336 | PGS001803 (portability-PLR_172) |
PSS007725| African Ancestry| 2,483 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): -0.0065 [-0.046, 0.033] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009337 | PGS001803 (portability-PLR_172) |
PSS008827| African Ancestry| 3,924 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.0165 [-0.0149, 0.0479] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009841 | PGS001869 (portability-PLR_681) |
PSS009345| European Ancestry| 19,807 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): 0.0142 | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009842 | PGS001869 (portability-PLR_681) |
PSS009119| European Ancestry| 4,093 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): -0.0247 [-0.0554, 0.006] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009843 | PGS001869 (portability-PLR_681) |
PSS008673| European Ancestry| 6,586 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): -0.004 [-0.0282, 0.0201] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009844 | PGS001869 (portability-PLR_681) |
PSS008447| Greater Middle Eastern Ancestry| 1,189 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): 0.0014 [-0.0559, 0.0587] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009845 | PGS001869 (portability-PLR_681) |
PSS008227| South Asian Ancestry| 6,213 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): 0.0057 [-0.0192, 0.0306] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009846 | PGS001869 (portability-PLR_681) |
PSS008008| East Asian Ancestry| 1,803 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): -0.0207 [-0.0671, 0.0257] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009847 | PGS001869 (portability-PLR_681) |
PSS007792| African Ancestry| 2,440 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): -0.0078 [-0.0476, 0.0321] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009848 | PGS001869 (portability-PLR_681) |
PSS008896| African Ancestry| 3,853 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): -0.0033 [-0.0349, 0.0284] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009857 | PGS001871 (portability-PLR_696.4) |
PSS009347| European Ancestry| 19,615 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.0636 [0.0497, 0.0775] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009858 | PGS001871 (portability-PLR_696.4) |
PSS009121| European Ancestry| 4,059 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.107 [0.0764, 0.1374] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009859 | PGS001871 (portability-PLR_696.4) |
PSS008675| European Ancestry| 6,554 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.0404 [0.0162, 0.0646] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009860 | PGS001871 (portability-PLR_696.4) |
PSS008449| Greater Middle Eastern Ancestry| 1,183 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.0463 [-0.0112, 0.1035] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009861 | PGS001871 (portability-PLR_696.4) |
PSS008229| South Asian Ancestry| 6,161 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.0327 [0.0077, 0.0577] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009862 | PGS001871 (portability-PLR_696.4) |
PSS008010| East Asian Ancestry| 1,784 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.0079 [-0.0388, 0.0545] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009863 | PGS001871 (portability-PLR_696.4) |
PSS007794| African Ancestry| 2,398 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.0357 [-0.0045, 0.0757] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009864 | PGS001871 (portability-PLR_696.4) |
PSS008898| African Ancestry| 3,834 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): -0.0065 [-0.0382, 0.0252] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009865 | PGS001872 (portability-PLR_697) |
PSS009348| European Ancestry| 19,670 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0199 [0.0059, 0.0338] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009866 | PGS001872 (portability-PLR_697) |
PSS009122| European Ancestry| 4,059 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0123 [-0.0186, 0.0431] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009867 | PGS001872 (portability-PLR_697) |
PSS008676| European Ancestry| 6,565 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0166 [-0.0076, 0.0408] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009868 | PGS001872 (portability-PLR_697) |
PSS008450| Greater Middle Eastern Ancestry| 1,186 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0554 [-0.002, 0.1124] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009869 | PGS001872 (portability-PLR_697) |
PSS008230| South Asian Ancestry| 6,194 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.018 [-0.0069, 0.0429] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009871 | PGS001872 (portability-PLR_697) |
PSS008899| African Ancestry| 3,882 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0332 [0.0017, 0.0647] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009870 | PGS001872 (portability-PLR_697) |
PSS007795| African Ancestry| 2,441 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0157 [-0.0242, 0.0555] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009880 | PGS001874 (portability-PLR_706.2) |
PSS009351| European Ancestry| 19,952 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.0461 [0.0323, 0.06] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009881 | PGS001874 (portability-PLR_706.2) |
PSS009125| European Ancestry| 4,124 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.0709 [0.0404, 0.1013] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009882 | PGS001874 (portability-PLR_706.2) |
PSS008679| European Ancestry| 6,646 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.0466 [0.0225, 0.0706] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009883 | PGS001874 (portability-PLR_706.2) |
PSS008453| Greater Middle Eastern Ancestry| 1,194 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.0522 [-0.005, 0.1091] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009884 | PGS001874 (portability-PLR_706.2) |
PSS008233| South Asian Ancestry| 6,311 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.049 [0.0243, 0.0736] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009885 | PGS001874 (portability-PLR_706.2) |
PSS008013| East Asian Ancestry| 1,807 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): -0.0163 [-0.0627, 0.0301] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009886 | PGS001874 (portability-PLR_706.2) |
PSS007798| African Ancestry| 2,471 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): -0.0263 [-0.0659, 0.0133] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009887 | PGS001874 (portability-PLR_706.2) |
PSS008902| African Ancestry| 3,913 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): -0.01 [-0.0414, 0.0214] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010986 | PGS002014 (portability-ldpred2_172) |
PSS009273| European Ancestry| 19,990 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.1242 [0.1105, 0.1378] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010990 | PGS002014 (portability-ldpred2_172) |
PSS008155| South Asian Ancestry| 6,328 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): -0.0147 [-0.0394, 0.01] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010991 | PGS002014 (portability-ldpred2_172) |
PSS007943| East Asian Ancestry| 1,810 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): -0.0041 [-0.0504, 0.0423] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010992 | PGS002014 (portability-ldpred2_172) |
PSS007725| African Ancestry| 2,483 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): -0.0062 [-0.0457, 0.0333] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010993 | PGS002014 (portability-ldpred2_172) |
PSS008827| African Ancestry| 3,924 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.0146 [-0.0168, 0.0459] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010987 | PGS002014 (portability-ldpred2_172) |
PSS009047| European Ancestry| 4,134 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.0876 [0.0572, 0.1178] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010988 | PGS002014 (portability-ldpred2_172) |
PSS008601| European Ancestry| 6,656 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.076 [0.0521, 0.0999] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010989 | PGS002014 (portability-ldpred2_172) |
PSS008379| Greater Middle Eastern Ancestry| 1,200 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin cancer | — | — | Partial Correlation (partial-r): 0.0717 [0.0147, 0.1282] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011509 | PGS002081 (portability-ldpred2_681) |
PSS009345| European Ancestry| 19,807 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): 0.0247 [0.0108, 0.0386] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011510 | PGS002081 (portability-ldpred2_681) |
PSS009119| European Ancestry| 4,093 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): 0.0189 [-0.0118, 0.0496] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011511 | PGS002081 (portability-ldpred2_681) |
PSS008673| European Ancestry| 6,586 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): 0.009 [-0.0152, 0.0332] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011512 | PGS002081 (portability-ldpred2_681) |
PSS008447| Greater Middle Eastern Ancestry| 1,189 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): 0.021 [-0.0364, 0.0782] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011513 | PGS002081 (portability-ldpred2_681) |
PSS008227| South Asian Ancestry| 6,213 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): 0.0082 [-0.0167, 0.0331] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011514 | PGS002081 (portability-ldpred2_681) |
PSS008008| East Asian Ancestry| 1,803 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): -0.0251 [-0.0715, 0.0213] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011516 | PGS002081 (portability-ldpred2_681) |
PSS008896| African Ancestry| 3,853 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): -0.0005 [-0.0321, 0.0312] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011515 | PGS002081 (portability-ldpred2_681) |
PSS007792| African Ancestry| 2,440 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Superficial cellulitis and abscess | — | — | Partial Correlation (partial-r): -0.0119 [-0.0518, 0.0279] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011525 | PGS002083 (portability-ldpred2_696.4) |
PSS009347| European Ancestry| 19,615 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.0632 [0.0493, 0.0771] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011526 | PGS002083 (portability-ldpred2_696.4) |
PSS009121| European Ancestry| 4,059 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.1153 [0.0847, 0.1456] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011527 | PGS002083 (portability-ldpred2_696.4) |
PSS008675| European Ancestry| 6,554 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.041 [0.0168, 0.0652] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011529 | PGS002083 (portability-ldpred2_696.4) |
PSS008229| South Asian Ancestry| 6,161 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.03 [0.005, 0.055] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011530 | PGS002083 (portability-ldpred2_696.4) |
PSS008010| East Asian Ancestry| 1,784 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.0119 [-0.0348, 0.0585] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011531 | PGS002083 (portability-ldpred2_696.4) |
PSS007794| African Ancestry| 2,398 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.0375 [-0.0027, 0.0776] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011532 | PGS002083 (portability-ldpred2_696.4) |
PSS008898| African Ancestry| 3,834 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): -0.0166 [-0.0483, 0.0152] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011528 | PGS002083 (portability-ldpred2_696.4) |
PSS008449| Greater Middle Eastern Ancestry| 1,183 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Psoriasis | — | — | Partial Correlation (partial-r): 0.0458 [-0.0117, 0.1031] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011533 | PGS002084 (portability-ldpred2_697) |
PSS009348| European Ancestry| 19,670 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0184 [0.0044, 0.0324] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011534 | PGS002084 (portability-ldpred2_697) |
PSS009122| European Ancestry| 4,059 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0038 [-0.0271, 0.0346] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011535 | PGS002084 (portability-ldpred2_697) |
PSS008676| European Ancestry| 6,565 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0103 [-0.0139, 0.0345] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011536 | PGS002084 (portability-ldpred2_697) |
PSS008450| Greater Middle Eastern Ancestry| 1,186 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0603 [0.0029, 0.1173] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011537 | PGS002084 (portability-ldpred2_697) |
PSS008230| South Asian Ancestry| 6,194 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0182 [-0.0067, 0.0432] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011538 | PGS002084 (portability-ldpred2_697) |
PSS007795| African Ancestry| 2,441 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0131 [-0.0268, 0.0529] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011539 | PGS002084 (portability-ldpred2_697) |
PSS008899| African Ancestry| 3,882 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sarcoidosis | — | — | Partial Correlation (partial-r): 0.0187 [-0.0128, 0.0502] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011540 | PGS002085 (portability-ldpred2_702.2) |
PSS009349| European Ancestry| 19,837 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Seborrheic keratosis | — | — | Partial Correlation (partial-r): 0.0237 [0.0098, 0.0376] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011541 | PGS002085 (portability-ldpred2_702.2) |
PSS009123| European Ancestry| 4,111 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Seborrheic keratosis | — | — | Partial Correlation (partial-r): 0.03 | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011542 | PGS002085 (portability-ldpred2_702.2) |
PSS008677| European Ancestry| 6,626 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Seborrheic keratosis | — | — | Partial Correlation (partial-r): 0.0128 [-0.0113, 0.0369] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011543 | PGS002085 (portability-ldpred2_702.2) |
PSS008451| Greater Middle Eastern Ancestry| 1,197 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Seborrheic keratosis | — | — | Partial Correlation (partial-r): 0.0512 [-0.006, 0.108] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011544 | PGS002085 (portability-ldpred2_702.2) |
PSS008231| South Asian Ancestry| 6,321 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Seborrheic keratosis | — | — | Partial Correlation (partial-r): -0.0097 [-0.0344, 0.015] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011545 | PGS002085 (portability-ldpred2_702.2) |
PSS008011| East Asian Ancestry| 1,807 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Seborrheic keratosis | — | — | Partial Correlation (partial-r): -0.0149 [-0.0612, 0.0315] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011546 | PGS002085 (portability-ldpred2_702.2) |
PSS007796| African Ancestry| 2,483 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Seborrheic keratosis | — | — | Partial Correlation (partial-r): 0.0158 [-0.0237, 0.0553] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011547 | PGS002085 (portability-ldpred2_702.2) |
PSS008900| African Ancestry| 3,922 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Seborrheic keratosis | — | — | Partial Correlation (partial-r): -0.0283 [-0.0596, 0.0031] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011556 | PGS002087 (portability-ldpred2_706.2) |
PSS009351| European Ancestry| 19,952 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.0513 [0.0374, 0.0651] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011557 | PGS002087 (portability-ldpred2_706.2) |
PSS009125| European Ancestry| 4,124 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.0734 [0.0429, 0.1037] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011558 | PGS002087 (portability-ldpred2_706.2) |
PSS008679| European Ancestry| 6,646 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.0454 [0.0214, 0.0694] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011559 | PGS002087 (portability-ldpred2_706.2) |
PSS008453| Greater Middle Eastern Ancestry| 1,194 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.0444 [-0.0128, 0.1014] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011560 | PGS002087 (portability-ldpred2_706.2) |
PSS008233| South Asian Ancestry| 6,311 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.0351 [0.0103, 0.0597] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011561 | PGS002087 (portability-ldpred2_706.2) |
PSS008013| East Asian Ancestry| 1,807 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): -0.0299 [-0.0762, 0.0165] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011562 | PGS002087 (portability-ldpred2_706.2) |
PSS007798| African Ancestry| 2,471 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): -0.0274 [-0.067, 0.0122] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011563 | PGS002087 (portability-ldpred2_706.2) |
PSS008902| African Ancestry| 3,913 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Sebaceous cyst | — | — | Partial Correlation (partial-r): 0.0023 [-0.0291, 0.0338] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM013020 | PGS002293 (PRS62_psoriasis) |
PSS009651| European Ancestry| 345,672 individuals |
PGP000323 | Shen M et al. J Am Acad Dermatol (2022) |
Reported Trait: Incident psoriasis | HR: 4.625 [2.92, 7.348] | — | Odds Ratio (OR, poor lifestyle and high genetic risk): 4.625 [2.92, 7.348] Population-attributable fraction of genetic risk: 0.13 [0.032, 0.218] |
Age, sex, education, Townsend Index, and region, relatedness, number of alleles included in the polygenic risk score, and first 20 principal components of ancestry | — |
| PPM013085 | PGS002320 (disease_DERMATOLOGY.BOLT-LMM) |
PSS009723| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0005 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013134 | PGS002320 (disease_DERMATOLOGY.BOLT-LMM) |
PSS009724| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013183 | PGS002320 (disease_DERMATOLOGY.BOLT-LMM) |
PSS009725| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0032 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013232 | PGS002320 (disease_DERMATOLOGY.BOLT-LMM) |
PSS009726| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013109 | PGS002344 (disease_PSORIASIS.BOLT-LMM) |
PSS009819| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013158 | PGS002344 (disease_PSORIASIS.BOLT-LMM) |
PSS009820| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013207 | PGS002344 (disease_PSORIASIS.BOLT-LMM) |
PSS009821| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.007 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013256 | PGS002344 (disease_PSORIASIS.BOLT-LMM) |
PSS009822| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0035 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013373 | PGS002392 (disease_DERMATOLOGY.P+T.0.0001) |
PSS009723| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013422 | PGS002392 (disease_DERMATOLOGY.P+T.0.0001) |
PSS009724| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013471 | PGS002392 (disease_DERMATOLOGY.P+T.0.0001) |
PSS009725| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013520 | PGS002392 (disease_DERMATOLOGY.P+T.0.0001) |
PSS009726| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013397 | PGS002416 (disease_PSORIASIS.P+T.0.0001) |
PSS009819| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0005 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013446 | PGS002416 (disease_PSORIASIS.P+T.0.0001) |
PSS009820| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013495 | PGS002416 (disease_PSORIASIS.P+T.0.0001) |
PSS009821| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013544 | PGS002416 (disease_PSORIASIS.P+T.0.0001) |
PSS009822| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013569 | PGS002441 (disease_DERMATOLOGY.P+T.0.001) |
PSS009723| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013618 | PGS002441 (disease_DERMATOLOGY.P+T.0.001) |
PSS009724| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013667 | PGS002441 (disease_DERMATOLOGY.P+T.0.001) |
PSS009725| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013716 | PGS002441 (disease_DERMATOLOGY.P+T.0.001) |
PSS009726| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013593 | PGS002465 (disease_PSORIASIS.P+T.0.001) |
PSS009819| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0003 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013642 | PGS002465 (disease_PSORIASIS.P+T.0.001) |
PSS009820| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013691 | PGS002465 (disease_PSORIASIS.P+T.0.001) |
PSS009821| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013740 | PGS002465 (disease_PSORIASIS.P+T.0.001) |
PSS009822| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013765 | PGS002490 (disease_DERMATOLOGY.P+T.0.01) |
PSS009723| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013814 | PGS002490 (disease_DERMATOLOGY.P+T.0.01) |
PSS009724| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013863 | PGS002490 (disease_DERMATOLOGY.P+T.0.01) |
PSS009725| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013912 | PGS002490 (disease_DERMATOLOGY.P+T.0.01) |
PSS009726| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013789 | PGS002514 (disease_PSORIASIS.P+T.0.01) |
PSS009819| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0003 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013838 | PGS002514 (disease_PSORIASIS.P+T.0.01) |
PSS009820| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013887 | PGS002514 (disease_PSORIASIS.P+T.0.01) |
PSS009821| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013936 | PGS002514 (disease_PSORIASIS.P+T.0.01) |
PSS009822| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013961 | PGS002539 (disease_DERMATOLOGY.P+T.1e-06) |
PSS009723| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014010 | PGS002539 (disease_DERMATOLOGY.P+T.1e-06) |
PSS009724| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0037 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014059 | PGS002539 (disease_DERMATOLOGY.P+T.1e-06) |
PSS009725| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014108 | PGS002539 (disease_DERMATOLOGY.P+T.1e-06) |
PSS009726| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013985 | PGS002563 (disease_PSORIASIS.P+T.1e-06) |
PSS009819| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0004 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014034 | PGS002563 (disease_PSORIASIS.P+T.1e-06) |
PSS009820| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014083 | PGS002563 (disease_PSORIASIS.P+T.1e-06) |
PSS009821| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014132 | PGS002563 (disease_PSORIASIS.P+T.1e-06) |
PSS009822| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014157 | PGS002588 (disease_DERMATOLOGY.P+T.5e-08) |
PSS009723| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014206 | PGS002588 (disease_DERMATOLOGY.P+T.5e-08) |
PSS009724| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0022 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014255 | PGS002588 (disease_DERMATOLOGY.P+T.5e-08) |
PSS009725| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014304 | PGS002588 (disease_DERMATOLOGY.P+T.5e-08) |
PSS009726| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014181 | PGS002612 (disease_PSORIASIS.P+T.5e-08) |
PSS009819| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0007 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014230 | PGS002612 (disease_PSORIASIS.P+T.5e-08) |
PSS009820| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014279 | PGS002612 (disease_PSORIASIS.P+T.5e-08) |
PSS009821| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014328 | PGS002612 (disease_PSORIASIS.P+T.5e-08) |
PSS009822| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014353 | PGS002637 (disease_DERMATOLOGY.PolyFun-pred) |
PSS009723| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0005 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_DERMATOLOGY.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014402 | PGS002637 (disease_DERMATOLOGY.PolyFun-pred) |
PSS009724| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0009 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_DERMATOLOGY.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014451 | PGS002637 (disease_DERMATOLOGY.PolyFun-pred) |
PSS009725| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0032 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_DERMATOLOGY.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014500 | PGS002637 (disease_DERMATOLOGY.PolyFun-pred) |
PSS009726| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0011 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_DERMATOLOGY.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014377 | PGS002661 (disease_PSORIASIS.PolyFun-pred) |
PSS009819| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014426 | PGS002661 (disease_PSORIASIS.PolyFun-pred) |
PSS009820| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014475 | PGS002661 (disease_PSORIASIS.PolyFun-pred) |
PSS009821| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.007 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014524 | PGS002661 (disease_PSORIASIS.PolyFun-pred) |
PSS009822| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0034 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014598 | PGS002686 (disease_DERMATOLOGY.SBayesR) |
PSS009724| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014549 | PGS002686 (disease_DERMATOLOGY.SBayesR) |
PSS009723| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0011 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014647 | PGS002686 (disease_DERMATOLOGY.SBayesR) |
PSS009725| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0016 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014696 | PGS002686 (disease_DERMATOLOGY.SBayesR) |
PSS009726| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Dermatologic diseases | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014622 | PGS002710 (disease_PSORIASIS.SBayesR) |
PSS009820| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014671 | PGS002710 (disease_PSORIASIS.SBayesR) |
PSS009821| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0014 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014720 | PGS002710 (disease_PSORIASIS.SBayesR) |
PSS009822| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014573 | PGS002710 (disease_PSORIASIS.SBayesR) |
PSS009819| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Psoriasis | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014955 | PGS002755 (Atopic_dermatitis_prscs) |
PSS009939| European Ancestry| 39,444 individuals |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Reported Trait: Atopic dermatitis | OR: 1.28 [1.21, 1.34] | — | — | age, sex, 10 PCs, technical covariates | — |
| PPM020709 | PGS002755 (Atopic_dermatitis_prscs) |
PSS011376| European Ancestry| 337,910 individuals |
PGP000566 | Gu X et al. Ecotoxicol Environ Saf (2023) |Ext. |
Reported Trait: Incident atopic dermatitis | — | — | Hazard ratio (HR, high vs low PRS): 1.249 [1.123, 1.391] | sex, age, Townsend index, moderate physical and household income | — |
| PPM020710 | PGS002755 (Atopic_dermatitis_prscs) |
PSS011376| European Ancestry| 337,910 individuals |
PGP000566 | Gu X et al. Ecotoxicol Environ Saf (2023) |Ext. |
Reported Trait: Incident atopic dermatitis with air pollution level | — | — | Hazard ratio (HR, high air pollution and high PRS vs low air pollution and low PRS): 1.978 [1.624, 2.411] | sex, age, Townsend index, moderate physical and household income | — |
| PPM016257 | PGS003382 (best_SKCM) |
PSS010085| European Ancestry| 273,786 individuals |
PGP000413 | Namba S et al. Cancer Res (2022) |
Reported Trait: skin cutaneous melanoma | — | AUROC: 0.682 | R²: 0.0261 | age, sex, top 20 genetic principal components | — |
| PPM017069 | PGS003416 (MTAGPRS) |
PSS010113| European Ancestry| 18,933 individuals |
PGP000429 | Seviiri M et al. Nat Commun (2022) |
Reported Trait: Keratinocyte cancers | OR: 1.66 [1.55, 1.79] | — | — | age, sex, 10 ancesty PCs | — |
| PPM017070 | PGS003417 (UKBPRS) |
PSS010113| European Ancestry| 18,933 individuals |
PGP000429 | Seviiri M et al. Nat Commun (2022) |
Reported Trait: Keratinocyte cancers | OR: 1.56 [1.45, 1.67] | — | — | age, sex, 10 ancesty PCs | — |
| PPM017414 | PGS003459 (PRS_CO) |
PSS010186| European Ancestry| 3,212 individuals |
PGP000451 | Al-Janabi A et al. J Invest Dermatol (2023) |
Reported Trait: Paradoxical eczema in biologic-treated psoriasis | OR: 1.83 [1.17, 2.84] | AUROC: 0.585 | — | PCs 1-2 | — |
| PPM017412 | PGS003486 (PRS_AE) |
PSS010186| European Ancestry| 3,212 individuals |
PGP000451 | Al-Janabi A et al. J Invest Dermatol (2023) |
Reported Trait: Paradoxical eczema in biologic-treated psoriasis | OR: 1.89 [1.08, 3.3] | AUROC: 0.567 | — | PCs 1-2 | — |
| PPM018501 | PGS003745 (PRS57_SM) |
PSS010995| European Ancestry| 448 individuals |
PGP000470 | Xin J et al. EBioMedicine (2023) |
Reported Trait: Skin Melanoma | OR: 1.49 [1.34, 1.66] | — | — | — | — |
| PPM020312 | PGS004247 (PRS65_melanoma) |
PSS011329| European Ancestry| 115,207 individuals |
PGP000542 | Kim ES et al. NPJ Precis Oncol (2023) |
Reported Trait: Melanoma | HR: 1.71 [1.55, 1.89] | — | — | first 10 genetic principal components | — |
| PPM020304 | PGS004247 (PRS65_melanoma) |
PSS011328| European Ancestry| 133,830 individuals |
PGP000542 | Kim ES et al. NPJ Precis Oncol (2023) |
Reported Trait: Melanoma | HR: 1.78 [1.62, 1.96] | — | — | first 10 genetic principal components | — |
| PPM020328 | PGS004260 (GenoBoost_psoriasis_0) |
PSS011347| European Ancestry| 67,428 individuals |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Reported Trait: Psoriasis | — | AUROC: 0.66908 | Covariate-adjusted pseudo-R2: 0.04239 AUPRC: 0.04468 |
age, sex, PC1-10 | — |
| PPM020329 | PGS004261 (GenoBoost_psoriasis_1) |
PSS011347| European Ancestry| 67,428 individuals |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Reported Trait: Psoriasis | — | AUROC: 0.67722 | Covariate-adjusted pseudo-R2: 0.04563 AUPRC: 0.0457 |
age, sex, PC1-10 | — |
| PPM020330 | PGS004262 (GenoBoost_psoriasis_2) |
PSS011347| European Ancestry| 67,428 individuals |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Reported Trait: Psoriasis | — | AUROC: 0.66916 | Covariate-adjusted pseudo-R2: 0.04211 AUPRC: 0.0431 |
age, sex, PC1-10 | — |
| PPM020331 | PGS004263 (GenoBoost_psoriasis_3) |
PSS011347| European Ancestry| 67,428 individuals |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Reported Trait: Psoriasis | — | AUROC: 0.67205 | Covariate-adjusted pseudo-R2: 0.04423 AUPRC: 0.04681 |
age, sex, PC1-10 | — |
| PPM020332 | PGS004264 (GenoBoost_psoriasis_4) |
PSS011347| European Ancestry| 67,428 individuals |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Reported Trait: Psoriasis | — | AUROC: 0.66842 | Covariate-adjusted pseudo-R2: 0.04356 AUPRC: 0.04551 |
age, sex, PC1-10 | — |
| PPM020383 | PGS004315 (GRS-ALL) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Family history of psoriasis | OR: 1.02 [1.0, 1.04] | — | R²: 0.0067 | — | — |
| PPM020384 | PGS004315 (GRS-ALL) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Age of psoriasis onset | OR: 0.71 [0.59, 0.85] | — | R²: 0.023 | — | — |
| PPM020386 | PGS004315 (GRS-ALL) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Age of type1 psoriasis onset | OR: 0.82 [0.59, 0.85] | — | R²: 0.0206 | — | — |
| PPM020388 | PGS004315 (GRS-ALL) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Psoriasis severity | OR: 1.02 [1.0, 1.06] | — | R²: 0.061 | — | — |
| PPM020390 | PGS004315 (GRS-ALL) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Total number of locations ever affected by psoriasis | OR: 1.16 [1.11, 1.21] | — | R²: 0.061 | — | — |
| PPM020393 | PGS004315 (GRS-ALL) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Initial presentation of psoriasis at elbow or knee | OR: 0.97 [0.94, 0.99] | — | — | — | — |
| PPM020396 | PGS004315 (GRS-ALL) |
PSS011348| European Ancestry| 345 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Psoriasis in genital area | β: -0.037 (0.016) | — | — | — | — |
| PPM020385 | PGS004316 (GRS-HLA) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Age of psoriasis onset | OR: 0.46 [0.34, 0.63] | — | R²: 0.0398 | — | — |
| PPM020387 | PGS004316 (GRS-HLA) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Age of type1 psoriasis onset | OR: 0.69 [0.56, 0.86] | — | R²: 0.0216 | — | — |
| PPM020389 | PGS004316 (GRS-HLA) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Psoriasis severity | OR: 1.09 [1.03, 1.15] | — | R²: 0.077 | — | — |
| PPM020391 | PGS004316 (GRS-HLA) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Total number of locations ever affected by psoriasis | OR: 1.34 [1.24, 1.45] | — | R²: 0.077 | — | — |
| PPM020394 | PGS004316 (GRS-HLA) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Initial presentation of psoriasis at elbow or knee | OR: 0.92 [0.88, 0.96] | — | — | — | — |
| PPM020392 | PGS004317 (GRS-noHLA) |
PSS011349| European Ancestry| 654 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Psoriasis in genital area | OR: 0.97 [0.94, 1.0] | — | — | — | — |
| PPM020395 | PGS004317 (GRS-noHLA) |
PSS011348| European Ancestry| 345 individuals |
PGP000547 | Bui A et al. Front Genet (2023) |
Reported Trait: Psoriasis in genital area | β: -0.038 (0.019) | — | — | — | — |
| PPM020437 | PGS004324 (PRS6314_PN) |
PSS011361| European Ancestry| 405,582 individuals |
PGP000558 | Vasavda C et al. J Invest Dermatol (2023) |
Reported Trait: Prurigo nodularis | OR: 1.27 | — | — | race, age, and sex | — |
| PPM020707 | PGS004587 (PRS23_AD) |
PSS011376| European Ancestry| 337,910 individuals |
PGP000566 | Gu X et al. Ecotoxicol Environ Saf (2023) |
Reported Trait: Incident atopic dermatitis | — | — | Hazard ratio (HR, high vs low PRS): 1.153 [1.037, 1.282] | sex, age, Townsend index, moderate physical and household income | — |
| PPM020708 | PGS004587 (PRS23_AD) |
PSS011376| European Ancestry| 337,910 individuals |
PGP000566 | Gu X et al. Ecotoxicol Environ Saf (2023) |
Reported Trait: Incident atopic dermatitis with air pollution level | — | — | Hazard ratio (HR, high air pollution and high PRS vs low air pollution and low PRS): 1.523 [1.259, 1.84] | sex, age, Townsend index, moderate physical and household income | — |
| PPM020722 | PGS004592 (PRS_KC) |
PSS011383| European Ancestry| 998 individuals |
PGP000571 | Liyanage UE et al. J Eur Acad Dermatol Venereol (2022) |
Reported Trait: Keratinocyte cancer | OR: 1.51 [1.3, 1.76] | AUROC: 0.74 | R²: 0.231 | Age, sex, self-reported skin tanning ability, clinical grade of neck elastosis, genotyping batch, first 2 PCs | — |
| PPM020723 | PGS004592 (PRS_KC) |
PSS011383| European Ancestry| 998 individuals |
PGP000571 | Liyanage UE et al. J Eur Acad Dermatol Venereol (2022) |
Reported Trait: Keratinocyte cancer | — | — | Odds ratio (OR, top PRS quintile vs bottom PRS quintile): 3.45 [2.18, 5.5] | Age, sex, self-reported skin tanning ability, clinical grade of neck elastosis, genotyping batch, first 2 PCs | — |
| PPM021335 | PGS004903 (PRS_ALL) |
PSS011691| European Ancestry| 3,212 individuals |
PGP000633 | Al-Janabi A et al. J Allergy Clin Immunol (2023) |
Reported Trait: Paradoxical eczema in individuals with psoriasis | — | — | Coefficient: 4.77 [0.58, 8.96] p: 0.026 |
— | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS004156 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004157 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004158 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004159 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004160 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004161 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004162 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS011691 | — | — | [
|
— | European | — | BSTOP | — |
| PSS004168 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004169 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004170 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004171 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004172 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004173 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004174 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004175 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004176 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004177 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004178 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004179 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004180 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004181 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004182 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS008155 | — | — | 6,328 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS008673 | — | — | 6,586 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS008675 | — | — | 6,554 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS008676 | — | — | 6,565 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS008677 | — | — | 6,626 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS008679 | — | — | 6,646 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS008227 | — | — | 6,213 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS008229 | — | — | 6,161 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS008230 | — | — | 6,194 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS008231 | — | — | 6,321 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS008233 | — | — | 6,311 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS007725 | — | — | 2,483 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS009273 | — | — | 19,990 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS000463 | Unaffected family members from families with increased melaona risk. Recruited families were ranked as low-, medium- or high-risk using a risk index (T) that factored in the number of confirmed cases of melanoma versus number of unaffected family members, ages and year of birth | — | [ ,
46.28 % Male samples |
— | European | Australia | BATS, QFMP | — |
| PSS000464 | Unaffected family members from families with increased melaona risk. Recruited families were ranked as low-, medium- or high-risk using a risk index (T) that factored in the number of confirmed cases of melanoma versus number of unaffected family members, ages and year of birth | — | [ ,
46.37 % Male samples |
— | European | Australia | BATS, QFMP | — |
| PSS000207 | PheCode 172 | — | [ ,
46.9 % Male samples |
Mean = 54.2 years Sd = 15.9 years |
European | — | MGI | — |
| PSS000209 | Basal cell carcinoma: ICD9-173.01,173.11,173.21,173.31,173.41,173.51,173.61,173.71,173.81,173.91 | — | [ ,
46.9 % Male samples |
Mean = 54.2 years Sd = 15.9 years |
European | — | MGI | — |
| PSS000211 | PheCode 172 | — | [ ,
45.9 % Male samples |
Mean = 57.7 years Sd = 8.1 years |
European | White British Subset | UKB | — |
| PSS007792 | — | — | 2,440 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS007794 | — | — | 2,398 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS007795 | — | — | 2,441 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS007796 | — | — | 2,483 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS007798 | — | — | 2,471 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS008827 | — | — | 3,924 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS009345 | — | — | 19,807 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS009347 | — | — | 19,615 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS009348 | — | — | 19,670 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS009349 | — | — | 19,837 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS009351 | — | — | 19,952 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS009651 | — | Median = 10.88 years | 345,672 individuals, 48.0 % Male samples |
Mean = 56.53 years Sd = 8.06 years |
European | — | UKB | — |
| PSS000489 | The diagnosttic criteria for each disease was based on gold-standard clinical guidelines. | — | 339 individuals | — | European (Spanish) |
— | PRECISESADS | — |
| PSS004876 | — | — | 5,650 individuals | — | African unspecified | — | UKB | — |
| PSS004877 | — | — | 1,297 individuals | — | East Asian | — | UKB | — |
| PSS004878 | — | — | 19,358 individuals | — | European | non-white British ancestry | UKB | — |
| PSS004879 | — | — | 6,219 individuals | — | South Asian | — | UKB | — |
| PSS004880 | — | — | 50,754 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS010085 | C43 | — | [
|
— | European (British) |
— | UKB | Controls were samples without any cancer diagnosis or self-reported cancer |
| PSS009939 | — | — | 39,444 individuals | — | European (Finnish) |
— | FinnGen | — |
| PSS004384 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004385 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004386 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004387 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004388 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS000871 | Basal cell carcinoma cases were determined by a baseline survey containing 34 questions regarding personal history of skin cancer(including skin cancer type, age at diagnosis, body location, prescribed treatments and information regarding cancer recurrence) | — | [ ,
38.9 % Male samples |
European | — | 23andMe | — | |
| PSS000544 | PheCode:172.21; ICD9CM:173.01, 173.11, 173.21, 173.31, 173.41, 173.51, 173.61, 173.71, 173.81, 173.91; ICD10CM:C44.01, C44.111, C44.112, C44.119, C44.211, C44.212, C44.219, C44.310, C44.311, C44.319, C44.41, C44.510, C44.511, C44.519, C44.611, C44.612, C44.619, C44.711, C44.712, C44.719, C44.81, C44.91 | — | [
|
— | European | — | MGI | — |
| PSS008379 | — | — | 1,200 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS000546 | PheCode:172.2; ICD9CM:173.00, 173.01, 173.02, 173.09, 173.10, 173.11, 173.12, 173.19, 173.20, 173.21, 173.22, 173.29, 173.30, 173.31, 173.32, 173.39, 173.40, 173.41, 173.42, 173.49, 173.50, 173.51, 173.52, 173.59, 173.60, 173.61, 173.62, 173.69, 173.70, 173.71, 173.72, 173.79, 173.80, 173.81, 173.82, 173.89, 173.90, 173.91, 173.92, 173.99, 209.31, 209.32, 209.33, 209.34, 209.35, 209.36, V10.83; ICD10CM:C44.0, C44.00, C44.01, C44.02, C44.09, C44.1, C44.10, C44.101, C44.102, C44.109, C44.11, C44.111, C44.112, C44.119, C44.12, C44.121, C44.122, C44.129, C44.19, C44.191, C44.192, C44.199, C44.2, C44.20, C44.201, C44.202, C44.209, C44.21, C44.211, C44.212, C44.219, C44.22, C44.221, C44.222, C44.229, C44.29, C44.291, C44.292, C44.299, C44.30, C44.300, C44.301, C44.309, C44.31, C44.310, C44.311, C44.319, C44.320, C44.321, C44.329, C44.39, C44.390, C44.391, C44.399, C44.4, C44.40, C44.41, C44.42, C44.49, C44.500, C44.501, C44.509, C44.51, C44.510, C44.511, C44.519, C44.52, C44.520, C44.521, C44.529, C44.59, C44.590, C44.591, C44.599, C44.6, C44.60, C44.601, C44.602, C44.609, C44.61, C44.611, C44.612, C44.619, C44.62, C44.621, C44.622, C44.629, C44.69, C44.691, C44.692, C44.699, C44.7, C44.70, C44.701, C44.702, C44.709, C44.71, C44.711, C44.712, C44.719, C44.72, C44.721, C44.722, C44.729, C44.79, C44.791, C44.792, C44.799, C44.8, C44.80, C44.81, C44.82, C44.89, C44.9, C44.90, C44.91, C44.92, C44.99, C4A, C4A.0, C4A.1, C4A.10, C4A.11, C4A.12, C4A.2, C4A.20, C4A.21, C4A.22, C4A.3, C4A.30, C4A.31, C4A.39, C4A.4, C4A.5, C4A.51, C4A.52, C4A.59, C4A.6, C4A.60, C4A.61, C4A.62, C4A.7, C4A.70, C4A.71, C4A.72, C4A.8, C4A.9 | — | [
|
— | European | — | MGI | — |
| PSS000547 | PheCode:172.3; ICD9CM:232.0, 232.1, 232.2, 232.3, 232.4, 232.5, 232.6, 232.7, 232.8, 232.9; ICD10CM:D04, D04.0, D04.1, D04.10, D04.11, D04.12, D04.2, D04.20, D04.21, D04.22, D04.3, D04.30, D04.39, D04.4, D04.5, D04.6, D04.60, D04.61, D04.62, D04.7, D04.70, D04.71, D04.72, D04.8, D04.9 | — | [
|
— | European | — | MGI | — |
| PSS000548 | PheCode:172; ICD9CM:172.0, 172.1, 172.2, 172.3, 172.4, 172.5, 172.6, 172.7, 172.8, 172.9, 173.00, 173.01, 173.02, 173.09, 173.10, 173.11, 173.12, 173.19, 173.20, 173.21, 173.22, 173.29, 173.30, 173.31, 173.32, 173.39, 173.40, 173.41, 173.42, 173.49, 173.50, 173.51, 173.52, 173.59, 173.60, 173.61, 173.62, 173.69, 173.70, 173.71, 173.72, 173.79, 173.80, 173.81, 173.82, 173.89, 173.90, 173.91, 173.92, 173.99, 209.31, 209.32, 209.33, 209.34, 209.35, 209.36, 232.0, 232.1, 232.2, 232.3, 232.4, 232.5, 232.6, 232.7, 232.8, 232.9, V10.82, V10.83; ICD10CM:C43, C43.0, C43.1, C43.10, C43.11, C43.12, C43.2, C43.20, C43.21, C43.22, C43.3, C43.30, C43.31, C43.39, C43.4, C43.5, C43.51, C43.52, C43.59, C43.6, C43.60, C43.61, C43.62, C43.7, C43.70, C43.71, C43.72, C43.8, C43.9, C44.0, C44.00, C44.01, C44.02, C44.09, C44.1, C44.10, C44.101, C44.102, C44.109, C44.11, C44.111, C44.112, C44.119, C44.12, C44.121, C44.122, C44.129, C44.19, C44.191, C44.192, C44.199, C44.2, C44.20, C44.201, C44.202, C44.209, C44.21, C44.211, C44.212, C44.219, C44.22, C44.221, C44.222, C44.229, C44.29, C44.291, C44.292, C44.299, C44.30, C44.300, C44.301, C44.309, C44.31, C44.310, C44.311, C44.319, C44.320, C44.321, C44.329, C44.39, C44.390, C44.391, C44.399, C44.4, C44.40, C44.41, C44.42, C44.49, C44.500, C44.501, C44.509, C44.51, C44.510, C44.511, C44.519, C44.52, C44.520, C44.521, C44.529, C44.59, C44.590, C44.591, C44.599, C44.6, C44.60, C44.601, C44.602, C44.609, C44.61, C44.611, C44.612, C44.619, C44.62, C44.621, C44.622, C44.629, C44.69, C44.691, C44.692, C44.699, C44.7, C44.70, C44.701, C44.702, C44.709, C44.71, C44.711, C44.712, C44.719, C44.72, C44.721, C44.722, C44.729, C44.79, C44.791, C44.792, C44.799, C44.8, C44.80, C44.81, C44.82, C44.89, C44.9, C44.90, C44.91, C44.92, C44.99, C4A, C4A.0, C4A.1, C4A.10, C4A.11, C4A.12, C4A.2, C4A.20, C4A.21, C4A.22, C4A.3, C4A.30, C4A.31, C4A.39, C4A.4, C4A.5, C4A.51, C4A.52, C4A.59, C4A.6, C4A.60, C4A.61, C4A.62, C4A.7, C4A.70, C4A.71, C4A.72, C4A.8, C4A.9, D03, D03.0, D03.1, D03.10, D03.11, D03.12, D03.2, D03.20, D03.21, D03.22, D03.3, D03.30, D03.39, D03.4, D03.5, D03.51, D03.52, D03.59, D03.6, D03.60, D03.61, D03.62, D03.7, D03.70, D03.71, D03.72, D03.8, D03.9, D04, D04.0, D04.1, D04.10, D04.11, D04.12, D04.2, D04.20, D04.21, D04.22, D04.3, D04.30, D04.39, D04.4, D04.5, D04.6, D04.60, D04.61, D04.62, D04.7, D04.70, D04.71, D04.72, D04.8, D04.9 | — | [
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— | European | — | MGI | — |
| PSS008896 | — | — | 3,853 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS008898 | — | — | 3,834 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS008899 | — | — | 3,882 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS008900 | — | — | 3,922 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS008902 | — | — | 3,913 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS000568 | PheCode:172.21; ICD9:173, 173.0, 173.1, 173.2, 173.3, 173.4, 173.5, 173.6, 173.7, 173.8, 173.9; ICD10:C44.0, C44.1, C44.2, C44.3, C44.4, C44.5, C44.6, C44.7, C44.8, C44.9 | — | [
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— | European | — | UKB | — |
| PSS011328 | — | — | 133,830 individuals, 0.0 % Male samples |
— | European (British) |
— | UKB | — |
| PSS011329 | — | — | 115,207 individuals, 100.0 % Male samples |
— | European (British) |
— | UKB | — |
| PSS000907 | Cases are individuals with vitiligo. Diagnoses of vitiligo in multiplex-affected subjects and reportedly unaffected family members were verified by manual review of all available phenotype information for each subject. | — | [
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— | European | — | NR | — |
| PSS010113 | — | — | 18,933 individuals | — | European | — | CLSA | — |
| PSS011347 | — | — | [ ,
46.0 % Male samples |
— | European (White British) |
— | UKB | — |
| PSS011348 | — | — | 345 individuals, 52.0 % Male samples |
Mean = 49.0 years Sd = 16.0 years |
European | — | UCSF | — |
| PSS011349 | — | — | 654 individuals, 48.0 % Male samples |
Mean = 41.0 years Sd = 14.0 years |
European | — | NR | — |
| PSS004471 | — | — | [
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— | African unspecified | — | UKB | — |
| PSS004472 | — | — | [
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— | East Asian | — | UKB | — |
| PSS004473 | — | — | [
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— | European | non-white British ancestry | UKB | — |
| PSS004474 | — | — | [
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— | South Asian | — | UKB | — |
| PSS004475 | — | — | [
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— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS008447 | — | — | 1,189 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS008449 | — | — | 1,183 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS008450 | — | — | 1,186 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS007943 | — | — | 1,810 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS008453 | — | — | 1,194 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS008451 | — | — | 1,197 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS011361 | — | — | [
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— | European | — | UKB | — |
| PSS010968 | — | — | [
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— | European | — | NR | GCAT |
| PSS010969 | — | — | [
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— | European | — | NR | GCAT |
| PSS010974 | — | — | [
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— | European | — | NR | GCAT |
| PSS010977 | — | — | 4,987 individuals | — | European | — | NR | GCAT |
| PSS004516 | — | — | [
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— | African unspecified | — | UKB | — |
| PSS010980 | — | — | 4,797 individuals | — | European | — | NR | GCAT |
| PSS004517 | — | — | [
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— | East Asian | — | UKB | — |
| PSS004518 | — | — | [
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— | European | non-white British ancestry | UKB | — |
| PSS004519 | — | — | [
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— | South Asian | — | UKB | — |
| PSS004521 | — | — | [
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— | African unspecified | — | UKB | — |
| PSS004522 | — | — | [
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— | East Asian | — | UKB | — |
| PSS004523 | — | — | [
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— | European | non-white British ancestry | UKB | — |
| PSS004524 | — | — | [
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— | South Asian | — | UKB | — |
| PSS004525 | — | — | [
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— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004520 | — | — | [
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— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS009723 | — | — | 6,503 individuals | — | African unspecified | — | UKB | — |
| PSS009724 | — | — | 922 individuals | — | East Asian | — | UKB | — |
| PSS009725 | — | — | 43,505 individuals | — | European | Non-British European | UKB | — |
| PSS009726 | — | — | 8,098 individuals | — | South Asian | — | UKB | — |
| PSS011376 | — | Median = 12.0 years | 337,910 individuals, 45.6 % Male samples |
Mean = 57.1 years Sd = 8.0 years |
European | — | UKB | — |
| PSS008008 | — | — | 1,803 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS008010 | — | — | 1,784 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS008011 | — | — | 1,807 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS007621 | — | — | [
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— | African unspecified | — | UKB | — |
| PSS007622 | — | — | [
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— | East Asian | — | UKB | — |
| PSS007623 | — | — | [
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— | European | non-white British ancestry | UKB | — |
| PSS007624 | — | — | [
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— | South Asian | — | UKB | — |
| PSS007625 | — | — | [
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— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS008013 | — | — | 1,807 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS011383 | — | — | [ ,
44.0 % Male samples |
— | European | — | NSCS | — |
| PSS009047 | — | — | 4,134 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS010995 | — | — | 448 individuals | Mean = 58.23 years | European | — | TCGA | — |
| PSS007651 | — | — | [
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— | African unspecified | — | UKB | — |
| PSS007652 | — | — | [
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— | East Asian | — | UKB | — |
| PSS007653 | — | — | [
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— | European | non-white British ancestry | UKB | — |
| PSS007654 | — | — | [
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— | South Asian | — | UKB | — |
| PSS007655 | — | — | [
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— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS007661 | For the CHILD Cohort Study, atopic dermatitis (AD) was from physician diagnosis at the one year follow-up. AD severity was defined as mild if there is a single site or no more than 2 sites, minor symptoms (little itching/rubbing), minor crusting and papules, not excoriated or oozing, not needing frequent medical attention; was defined as moderate if symptoms are neither mild nor severe or; was defined as severe if there are multiple sites, with extensive crusting or papules or excoriations or oozing or lichenification, sleep loss, needing frequent medical attention, and is a major concern to parents. In the SLSJ Cohort, atopic dermatitis was self-reported and considered as positive if past or present occurrence was reported. For children, cross validation was done using questionnaires filled by their parents. Moreover, validation in medical records of these self-reported phenotypes were done for a subset of the SLSJ Cohort (n = 217), giving 89% concordance. | — | [ ,
42.0 % Male samples |
Mean = 9.0 years Range = [0.0, 87.0] years |
European, South East Asian, East Asian, South Asian, African American or Afro-Caribbean, Native American, Greater Middle Eastern (Middle Eastern, North African or Persian), Hispanic or Latin American, Not reported | — | CHILD, SLSJ | Also used to evaluate the PRS_atopicDermatitis for other diseases of the atopic march: food allergy, allergic asthma and rhinitis. Only unrelated individuals were selected for analyses. |
| PSS000970 | — | Median = 400.0 days | 1,584 individuals | — | European | — | GNEHGI2020Q2 | — |
| PSS009819 | — | — | 6,503 individuals | — | African unspecified | — | UKB | — |
| PSS009820 | — | — | 922 individuals | — | East Asian | — | UKB | — |
| PSS009821 | — | — | 43,505 individuals | — | European | Non-British European | UKB | — |
| PSS009822 | — | — | 8,098 individuals | — | South Asian | — | UKB | — |
| PSS008601 | — | — | 6,656 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS010186 | Plaque psoriasis patients with at least one exposure to biologic therapy. Cases developed one or more paradoxical eczema adverse events during treatment with one of the following biologics: TNF-alpha inhibitors (adalimumab; etanercept; certolizumab; infliximab), IL-17 inhibitors (brodalumab; secukinumab; ixekizumab), IL-12/23 inhibitors (ustekinumab) and IL-23p19 inhibitors (guselkumab; risankizumab; tildrakizumab). Controls has no recorded eczema events during biologic therapy. Participants may have been exposed to more than one biologic. | — | [
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— | European | — | BSTOP | — |
| PSS009119 | — | — | 4,093 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS009121 | — | — | 4,059 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS009122 | — | — | 4,059 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS009123 | — | — | 4,111 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS000982 | Cases were individuals with cutaneous melanoma. Of the 628 cases, 528 were prevalent melanoma, whilst 98 were incident melanoma cases. Endpoints used were primary invasive cutaneous melanoma and metastatic melanoma with unknown primary location occurring during the trial (incident). Metastatic recurrence was excluded. Incident melanomas were confirmed by expert panel using histopathology, imaging of metastasis or other clinical evidence. If a participant had two events during the trial, the time of the first event was used. Prevalent melanomas occurring pre-trial were self-reported by participants but not confirmed by review of medical records and assumed to be invasive. Age at diagnosis for self-reported melanomas was reported as either before or after 50 years. | Median = 4.7 years | [ ,
45.0 % Male samples |
Mean = 75.0 years Sd = 4.23 years |
European | — | ASPREE | — |
| PSS009125 | — | — | 4,124 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS004153 | — | — | [
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— | African unspecified | — | UKB | — |
| PSS004154 | — | — | [
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— | East Asian | — | UKB | — |
| PSS004155 | — | — | [
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— | European | non-white British ancestry | UKB | — |